Pages
פברואר 05, 2018
-
Date:13רביעייוני 2018הרצאה
G-INCPM - Special Seminar - Prof. Asaph Aharoni, Dept. of Plant & Environmental Sciences, Faculty of Biochemistry, Weizmann - "The Plant Metabolome in Action"
More information שעה 11:00 - 12:30מיקום המרכז הישראלי הלאומי לרפואה מותאמת אישית על-שם ננסי וסטיבן גרנדמרצה Prof. Asaph Aharoni
Dept. of Plant & Environmental Sciences, Faculty of Biochemistry, Weizmannמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about The regulation of metabolic pathways in plants is constantly...» The regulation of metabolic pathways in plants is constantly tuned in order to suit the needs of development and fitness. Our main research objective is to unravel networks of genes and proteins which coordinate the activity of metabolic pathways, predominantly secondary metabolism, during plant development and stress response. An integrated investigation of several members of the Solanacea family rather than studying a single plant, provided us with unprecedented insights to metabolic biology in these species. Most if not all processes characterized, impact to a certain degree key quality, nutritional and post-harvest traits of these crop plants. Integrating cutting-edge transcriptomics, proteomics and metabolomics tools together with genes co-expression assays were of great value in making several key discoveries. In a recent example, combined co-expression analysis and metabolic profiling in tomato and potato led to the discovery of the multi-step, core pathway leading to the formation of the renowned Solanum alkaloids including the biosynthesis of their precursor, cholesterol. This class of molecules represent important anti-nutritional compounds in these crop plants. In the presentation, I will highlight several advanced technologies and genetic research tools and the invaluable knowledge on core metabolic traits obtained through combining them in a single study. -
Date:13רביעייוני 2018הרצאה
Organic Bio-crystallization: Optically Functional Organic Crystals in Animals Provide Inspiration for New Materials
More information שעה 14:00 - 15:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Dr. Benjamin Palmer
Department of Structural Biology, WISמארגן המחלקה לכימיה מולקולרית ולמדע חומריםצרו קשר -
Date:14חמישייוני 2018הרצאה
A. Screening surface properties of mesoporous carbon-based materials; B. Biomimetic CaCO3 crystallization and stability regulated by L-Asp
More information שעה 09:30 - 10:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Asher Schmidt
Schulich Faculty of Chemistry and Russell Berrie Nanotechnology Institute, Technionמארגן המחלקה לכימיה מולקולרית ולמדע חומריםצרו קשר -
Date:14חמישייוני 2018סימפוזיונים
Making Faces: Universal Inverse Design of Surfaces with Anisotropic Soft Materials
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Dr. Hillel Aharoni
University of Pennsylvaniaמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about Elastic bodies can be programmed to take different shapes in...» Elastic bodies can be programmed to take different shapes in different environments using stimulus-responsive anisotropic materials, where the route of shape changes is encoded in the local direction of material anisotropy at every point. In this talk I tackle the key theoretical question underlying many recent efforts to implement this approach — the inverse design problem — namely, given an arbitrary shape, constructing the anisotropy field that would induce it. I show analytical solutions to certain classes of this problem and a numerical algorithm to construct any surface geometry, and I resolve the problem of properly converting these 2D geometries into their destined 3D shapes. Finally, I team up with an experimental group in realizing this scheme by imprinting our numerical solutions into liquid crystalline elastomer sheets. We show success in experimentally producing flat rubber-like sheets that, upon heating, take an arbitrary preprogrammed desired shape, such as a face. -
Date:14חמישייוני 2018הרצאה
A ubiquitous human carcinogen guiding the early diagnosis of cancer
More information שעה 14:00 - 15:00כותרת Special Guest Seminarמיקום בניין ע"ש מקס ולילאן קנדיוטימרצה Prof. Arthur Grollman
Stony Brook University School of Medicine USAמארגן המחלקה לאימונולוגיה ורגנרציה ביולוגיתצרו קשר תקציר Show full text abstract about Aristolochic acid (AA) is now recognized as a causative agen...» Aristolochic acid (AA) is now recognized as a causative agent of several types of human cancer. Moreover, as a component of Aristolochia, a widely used medicinal herb, it is now clear that people have been exposed to toxic levels of AA for hundreds of years, worldwide. Today, tens of millions of people are at risk of developing AA-induced cancers of the upper urothelium, kidney, liver and biliary tract. In addition, aristolochic acid was proven to be the environmental agent responsible for Balkan endemic nephropathy and its associated urothelial cancer. And, exposure to AA accounts for the high prevalence of upper urothelial cancer in Taiwan, the highest in the world. It has also been shown that AA-induced cancers are accompanied by a unique mutational signature, which can be used to identify AA-induced cancers in individuals who would otherwise be undiagnosed until the later stages of disease. Such analyses have established the foundation for a noninvasive approach for detection of urothelial cancer in patients at risk. -
Date:17ראשוןיוני 201828חמישייוני 2018כנסים
RADIATION TRANSFER AND EXPLOSIVE THERMONUCLEAR BURNING IN SUPERNOVAE
More information שעה 08:00 - 08:00מיקום ספרית הפיסיקה על שם נלה וליאון בנוזיויושב ראש Doron Kushnirמארגן הפקולטה לפיזיקהדף בית -
Date:17ראשוןיוני 201828חמישייוני 2018כנסים
RADIATION TRANSFER AND EXPLOSIVE THERMONUCLEAR BURNING IN SUPERNOVAE
More information שעה 08:00 - 08:00מיקום ספרית הפיסיקה על שם נלה וליאון בנוזיויושב ראש Doron Kushnirמארגן הפקולטה לפיזיקהדף בית -
Date:17ראשוןיוני 2018הרצאה
Molecular Genetics Departmental Seminars 2017-2018
More information שעה 13:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Ronit Suissa מארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:18שנייוני 2018סימפוזיונים
Shneior Lifson Memorial Lecture: "Proton-Coupled Electron Transfer in Catalysis and Energy Conversion"
More information שעה 11:00 - 12:15מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Sharon Hammes-Schiffer
Department of Chemistry, Yale Universityמארגן הפקולטה לכימיהצרו קשר -
Date:19שלישייוני 2018כנסים
FROM CANCER GENOMICS TO IMMUNOTHERAPY
More information שעה 08:00 - 14:00מיקום אולם ע"ש דולפי ולולה אבנריושב ראש Yardena Samuelsדף בית -
Date:19שלישייוני 2018הרצאה
Chemical and Biological Physics Guest Seminar
More information שעה 09:30 - 09:30כותרת The fascinating photochemistry of Photosystem II unraveled with the use of low temperature EPR spectroscopyמיקום בניין פרלמן למדעי הכימיהמרצה Dr Andrea Pavlou
Molecular Biomimetics, Ångström Laboratory Uppsala University Swedenמארגן המחלקה לפיזיקה כימית וביולוגיתצרו קשר -
Date:19שלישייוני 2018הרצאה
Mechanisms of sparse coding in the dentate gyrus
More information שעה 12:30 - 13:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research Life and Brain Center, University of Bonn Medical Centerמארגן המחלקה למדעי המוחצרו קשר -
Date:19שלישייוני 2018הרצאה
Mini Symposium: Biophysical Characterization by Light Scattering
More information שעה 13:00 - 16:00מיקום בניין הלן ומילטון קימלמןמרצה Dr. Dan Some
Wyatt Technologyמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:20רביעייוני 201821חמישייוני 2018כנסים
The Annual Conference for Science and the Environment
More information שעה 08:00 - 08:00מיקום מרכז כנסים על-שם דויד לופאטייושב ראש Dan Yakirדף בית -
Date:20רביעייוני 2018הרצאה
Developmental Club Series 2017-2018
More information שעה 10:00 - 10:00כותרת Elucidating membrane dynamics across scalesמיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Prof. Ori Avinoam מארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:20רביעייוני 2018הרצאה
Special Guest Seminar
More information שעה 14:00 - 14:00כותרת “Regulation and coordination of intracellular trafficking pathways by molecular switches”מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Nava Segev
Professor, Department of Biochemistry and Molecular Genetics, School of Medicine, University of Illinois at Chicago, USAמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:21חמישייוני 2018הרצאה
New era in cryo electron microscopy reflected in studies of a bacteriophage phage at near atomic resolution
More information שעה 11:00 - 12:00מיקום בניין הלן ומילטון קימלמןמרצה Prof. Elena Orlova
Institute of Structural and Molecular Biology, Birkbeck College, Londonמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר תקציר Show full text abstract about During the last decade electron microscopy become a powerful...» During the last decade electron microscopy become a powerful tool in structural studies of large biological complexes. Cryo electron microscopy enabled us to reveal molecular dynamics of the complexes by analysis of samples in solution. This was made possible by long-standing efforts in sample preparations (cryo-EM imaging), in development of hardware, automation in data collection, methods in image analysis and, eventually, interpretation of results. Here I would like to share my experience in using these approaches in analysis of structural organisation of bacteriophages exemplified by the SPP1 phage. It is important to highlight critical steps in obtaining near-atomic resolution structures of the biocomplexes. We have obtained high resolution structures of main components of the phage such as a capsid and its nano-motor engaged into packaging of genome and its release. -
Date:21חמישייוני 2018סימפוזיונים
Multiple Scale Structures:From Faraday Waves to Soft Quasicrystals
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Ron Lifshitz
Raymond and Beverly Sackler School of Physics & Astronomy Tel Aviv Universityמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about For many years, quasicrystals were observed only as solid-st...» For many years, quasicrystals were observed only as solid-state metallic alloys, yet current research is actively exploring their formation in a variety of soft materials, including systems of macromolecules, nanoparticles, and colloids. Much effort is being invested in understanding the thermodynamic properties of these soft-matter quasicrystals in order to predict and possibly control the structures that form, and hopefully to shed light on the broader, yet unresolved, general questions of quasicrystal formation and stability. I shall give an explanation for the stability of certain soft-matter quasicrystals---inspired by the physics of a different phenomenon known as Faraday waves---and provide a recipe for designing pair potentials that yield so-called -
Date:21חמישייוני 2018הרצאה
What the nose tells the brain
More information שעה 12:30 - 13:30מרצה Prof. Dmitry Rinberg
Dept of Neuroscience & Physiology NYU Neuroscience Instituteמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about All living organisms extract chemical information from the s...» All living organisms extract chemical information from the surrounding world. We know a lot about the genetic, cellular, and anatomical organization of our sense of smell, which has similar organization from insects to mammals. However, we still do not know basic principles of odor coding, organization of the odor parameter space, and how odors are represented in the brain. In humans, odors are sensed by millions of receptor cells using ~350 types of receptor cells. Flies have 60 and mice ~1000 receptor types. An odor evokes a concentration-dependent spatial-temporal pattern of receptor cell activity. We are presented with an immensely complex combinatorial computation. And the central question of my research is to understand how these patterns are read by the brain.
In this talk I will present our recent results on testing a novel model for concentration-invariant odor coding based on temporal ranking of receptor. And then I will discuss our attempt to build a theory of odor space representation in the brain based on this model.
-
Date:21חמישייוני 2018הרצאה
Pelletron meeting - by invitation only
More information שעה 16:00 - 16:00צרו קשר