• Prof. Guy Shakhar

    Dendritic cell behavior:
    The dynamics of antigen sampling, chemokinesis, lymphatic migration
    Antigen presentation by dendritic cells as revealed by intravital imaging
  • Picture of Prof. Yechiel Shai

    Prof. Yechiel Shai

    Membrane-protein interaction and molecular recognition within the membrane milieu. Implication to the function and structure of membrane proteins.
    Assembly and organization of pore forming toxins and ion channels in membranes: Studies with isolated fragments and intact proteins.
    Molecular mechanism of membrane fusion and its inhibition: Studies with HIV and Sendai Virus.
    Molecular basis for cell selectivity by cytolytic antimicrobial peptides.

    Homepage
  • Prof. Dan Shahar

    Physics of electron's spin
    Quantum phase transitions: General transport studies and mesoscopics of the metal-insulator, superconductor-insulator and other transitions.
    Scanning tunneling experiments at ultra-low temperatures
    Fractional and integer quantum Hall effect and related phenomena.
    Experiments on materials at ultra low-temperatures.
  • Picture of Prof. Idit Shachar

    Prof. Idit Shachar

    Analyze the pathway regulateing the survival cascades in Chronic lymphocytic leukemia
    Collaboration with:  Dr Michal Haran, Kaplan Medical center
    Follow the mechanisms controlling homing of immune cells in health and disease.
    Determine the mechanisms regulating peripheral B cell maturation and survival in health and disease.

    Homepage
  • Prof. Michael Sela

    Importance of negligible amounts of a partner in antibody combinations
    An aptamer strategy to target oncogenic signaling in ErbB2 carrying human tumors.
    Collaboration with:  G. Mahlknecht , Y. Yarden G. Mahlknecht
    Synergy of antibodies towards decreasing pancreatic cancer.
    Collaboration with:  R. Maron, B. Schechter, Y. Yarden
    Towards vaccination: Generation of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.
    Collaboration with:  E. Witsch, Y. Yarden
    Mechanism of action of Copolymer 1 (Copaxone), a therapeutic vaccine against multiple sclerosis.
    Collaboration with:  R. Arnon
    Effective synergism by anti ErbB-2 mAb combinations comprising one mAb against the dimerization site of ErbB-2.
    Collaboration with:  Y. Yarden
    Monoclonal antibodies (mAbs) to ErbB-1 and ErbB-2 receptors and their role in potential anti-tumor strategy.
    Collaboration with:  B. Schechter, Y. Yarden
    Synergistic effects of combinations of mAb against distinct epitopes on EGFR/ErbB-1 and ErbB-2 receptors: accelerated receptor aggregation, down regulation and inhibition of tumor growth.
    Collaboration with:  B. Schechter, Y. Yarden
  • Picture of Prof. Menahem Segal

    Prof. Menahem Segal

    Intracellular calcium and structural/functional plasticity in cultured neurons.
    Collaboration with:  Dr. Eduard Korkotian
    Hippocampal plasticity and epilepsy following stress
    Collaboration with:  Dr. Nicola Maggio, Chaim Shiba Medical Center
    Stem cells in the study of Fragile X syndrome
    Collaboration with:  Dr. Dalit Ben Yosef, Ichilov Medical Center

    Homepage
  • Picture of Prof. Adam Schwimmer

    Prof. Adam Schwimmer

    String theory.
    Conformal field theory.
    Dynamics of gauge theory.
  • Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

    The cross-talk between the immune and nervous systems – autoimmunity as a mechanism of tissue repair: Molecular, cellular, physiological and behavioral aspects.
    Immunological aspects of neuronal loss in neurodegenerative and mental disorders (Alzheimer’s, ALS, Huntingdon, Glaucoma).
    Spinal cord injury and repair
    Development of vaccination for neurodegenerative disorders.
    Neurogenesis (stem cells) and inflammation in the CNS.

    Homepage
  • Picture of Prof. Oren Schuldiner

    Prof. Oren Schuldiner

    A genetic dissection of developmental axon regeneration
    Molecular mechanisms of neuronal remodeling during development: Developmental axon pruning in Drosophila
    The role of cell-cell interaction in regulating developmental axon pruning
    The role of intracellular signaling in regulating developmental axon pruning
    The role of trafficking in regulating developmental axon pruning
    Glia and their effect on neuronal growth and remodeling

    Homepage
  • Picture of Prof. Maya Schuldiner

    Prof. Maya Schuldiner

    Uncovering tethers, functions and regulators of membrane contact sites in yeast
    Mitochondria-Peroxisome contact sites
    Peroxisome-Plasma membrane contact sites
    Lipid Droplet-Mitochondria contact sites
    The proteome of contact sites
    Targeting and translocation to Organelles
    Uncovering a role for the Ssh1, the alternative, translocon in yeast
    Deciphering targeting of proteins to mitochondria
    Targeting of membrane proteins to peroxisomes
    Targeting priority of matrix proteins to peroxisomes
    Uncovering new peroxisomal proteins and their functions
    Collaboration with:  Dr. Einat Zalckvar
    Metabolite transport across the peroxisome membrane
    Peroxisome contact sites
    Peroxisome quality control
    Peroxisome targeting
    New peroxisomal enzymes and their functions
    Novel methodologies for systematic exploration of yeast organelle protein functions
    Creation of versatile yeast libraries
    High throughput electron microscopy techniques
    Translocation sensors
    High throughput expansion microscopy in yeast

    Homepage

Pages