• Picture of Prof. Yechiel Shai

    Prof. Yechiel Shai

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    Membrane-protein interaction and molecular recognition within the membrane milieu. Implication to the function and structure of membrane proteins.
    Assembly and organization of pore forming toxins and ion channels in membranes: Studies with isolated fragments and intact proteins.
    Molecular mechanism of membrane fusion and its inhibition: Studies with HIV and Sendai Virus.
    Molecular basis for cell selectivity by cytolytic antimicrobial peptides.

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  • Picture of Dr. Ephraim Shahmoon

    Dr. Ephraim Shahmoon

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    Quantum optics theory, quantum science
    Collective light-matter interactions in quantum emitter arrays
    Novel platforms for quantum science and technology
    Quantum fluctuation forces
    Dipole-dipole interactions and QED in confined geometries

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  • Prof. Dan Shahar

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    Physics of electron's spin
    Quantum phase transitions: General transport studies and mesoscopics of the metal-insulator, superconductor-insulator and other transitions.
    Scanning tunneling experiments at ultra-low temperatures
    Fractional and integer quantum Hall effect and related phenomena.
    Experiments on materials at ultra low-temperatures.
  • Picture of Prof. Idit Shachar

    Prof. Idit Shachar

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    Analyze the pathway regulateing the survival cascades in Chronic lymphocytic leukemia
    Collaboration with:  Dr Michal Haran, Kaplan Medical center
    Follow the mechanisms controlling homing of immune cells in health and disease.
    Determine the mechanisms regulating peripheral B cell maturation and survival in health and disease.

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  • Picture of Prof. Philipp Selenko

    Prof. Philipp Selenko

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    Neuronal alpha-synuclein aggregation in Parkinson's disease
    Collaboration with:  Daniella Goldfarb, Hagen Hofmann, Ori Avinoam, Atan Gross, Ami Navon
    Structural Biology, Cell Biology, Neurobiology, Biophysics
    NMR, EPR, smFRET, cryoEM, CLEM, optical microscopy, correlative imaging methods, advanced mammalian cell models.
    Cellular regulation of CPEB4 liquid-liquid phase separation
    Collaboration with:  Daniella Goldfarb, Hagen Hofmann, Koby Levi
    Structural Biology, Cell Biology, Neurobiology, Biophysics
    NMR, EPR, smFRET, cryoEM, CLEM, optical microscopy, correlative imaging methods, advanced mammalian cell models.

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  • Prof. Michael Sela

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    Importance of negligible amounts of a partner in antibody combinations
    An aptamer strategy to target oncogenic signaling in ErbB2 carrying human tumors.
    Collaboration with:  G. Mahlknecht , Y. Yarden G. Mahlknecht
    Synergy of antibodies towards decreasing pancreatic cancer.
    Collaboration with:  R. Maron, B. Schechter, Y. Yarden
    Towards vaccination: Generation of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.
    Collaboration with:  E. Witsch, Y. Yarden
    Mechanism of action of Copolymer 1 (Copaxone), a therapeutic vaccine against multiple sclerosis.
    Collaboration with:  R. Arnon
    Effective synergism by anti ErbB-2 mAb combinations comprising one mAb against the dimerization site of ErbB-2.
    Collaboration with:  Y. Yarden
    Monoclonal antibodies (mAbs) to ErbB-1 and ErbB-2 receptors and their role in potential anti-tumor strategy.
    Collaboration with:  B. Schechter, Y. Yarden
    Synergistic effects of combinations of mAb against distinct epitopes on EGFR/ErbB-1 and ErbB-2 receptors: accelerated receptor aggregation, down regulation and inhibition of tumor growth.
    Collaboration with:  B. Schechter, Y. Yarden
  • Picture of Prof. Rony Seger

    Prof. Rony Seger

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    The nuclear translocation of signaling protein as a drug target for cancer and inflammation
    The nuclear translocation of ERK
    The nuclear translocation of JNK and p38
    Develop peptide inhibitors of the nuclear translocation of ERK/JNK/p38 for the cure of cancer and inflammation
    Development of small molecular weight inhibitors of the nuclear translocation of ERK for the cure of cancer
    The subcellular localisation of AKT
    The mechanisms and roles of MEK nuclear translocation
    ERK1c in the regulation of Golgi fragmentation
    The mechanisms of golgi translocation of ERK1c
    Substrates of ERK1c in the Golgi
    Mechanism of ERK1c-regulated Golgi architecture

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  • Picture of Prof. Menahem Segal

    Prof. Menahem Segal

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    Intracellular calcium and structural/functional plasticity in cultured neurons.
    Collaboration with:  Dr. Eduard Korkotian
    Human Embryonic Stem Cells of Fragile X patients
    Collaboration with:  Prof. Dalit Ben Yosef (TAU)
    Network activity in cultured neurons
    Collaboration with:  Professor Elisha Moses (Physics)

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  • Picture of Prof. Adam Schwimmer

    Prof. Adam Schwimmer

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    String theory.
    Conformal field theory.
    Dynamics of gauge theory.
  • Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

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    The cross-talk between the immune and nervous systems – autoimmunity as a mechanism of tissue repair: Molecular, cellular, physiological and behavioral aspects.
    Immunological aspects of neuronal loss in neurodegenerative and mental disorders (Alzheimer’s, ALS, Huntingdon, Glaucoma).
    Spinal cord injury and repair
    Development of vaccination for neurodegenerative disorders.
    Neurogenesis (stem cells) and inflammation in the CNS.

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