Advanced Services|Immunohistochemistry

Single molecule Fluorescent In Situ Hybridization (smFISH)

Using the smFISH protocols, single RNA molecules can be detected and quantified in tissue sections,
whole mount samples and cell cultures.

smFISH illustration

smFISH illustration, courtesy of Binyamin Zuckerman, Ulitsky lab (also see relevant publication). 

We offer:

  • Assistance in designing probes
  • Protocol calibration
  • Troubleshooting
  • Imaging
  • Image analysis tools 

smFISH experiments in our unit can be performed in one of the following methods: