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January 01, 2013
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Date:06MondayMarch 2017Colloquia
"Surface studies and matter wave optics experiments with neutral helium beams"
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Bodil Holst
University of BergenOrganizer Faculty of ChemistryContact -
Date:06MondayMarch 2017Lecture
Metabolic regulation of normal and leukaemia stem cells: the role of reactive oxygen species, mitochondria transfer and nitric oxide
More information Time 14:00 - 15:00Title Cancer Research ClubLocation Max and Lillian Candiotty BuildingLecturer Prof. Tsvee Lapidot
Dept. of Immunology, Weizmann InstituteOrganizer Department of Immunology and Regenerative BiologyContact Abstract Show full text abstract about Bone marrow (BM) retained blood forming stem cells are prote...» Bone marrow (BM) retained blood forming stem cells are protected from DNA damaging agents including chemotherapy to prevent lethal infections and hematology failure. Stem cell chemotherapy resistance, requires dynamic interactions with BM stromal and endothelial cells and involves metabolic regulation of ROS, mitochondria transfer, and inhibition of NO. Leukemic stem cells initiate and maintain the disease and are the major target for clinical chemotherapy treatment. These malignant stem cells also reside in the BM and their chemotherapy resistance can lead to lethal leukemia relapse. Metabolic regulation of normal and leukemic stem cells in the bone marrow will be discussed. -
Date:06MondayMarch 2017Cultural Events
Dira Lehaskir - Children's theater
More information Time 17:30 - 17:30Location Michael Sela AuditoriumContact -
Date:07TuesdayMarch 2017Lecture
How did the first protein form(s) evolve?
More information Time 10:00 - 10:30Location Wolfson Building for Biological ResearchLecturer Dr. Maria Luisa Romero Romero
Member - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Short functional peptides are likely to have served as cruci...» Short functional peptides are likely to have served as crucial intermediates between a primordial RNA world and the extant protein world. Our working hypothesis is that relics of these ancestral peptides still exist in the form of key motifs in active sites of present-day proteins. One such motif, probably the most obvious one, is the P-loop (Walker A motif) that typically binds the transferred phosphate moiety of ATP. Overall, our results show that P-loop NTPases could have emerged from a relatively short P-loop containing peptide and that self-assembly played a key role in endowing biochemical function despite limited size and complexity. -
Date:07TuesdayMarch 2017Lecture
Designed by Nature: Reduced Protein Stability Prevents Promiscuous Protein Binding The Case of TEM1-β-Lactamase
More information Time 10:30 - 11:00Location Wolfson Building for Biological ResearchLecturer Ruth Khait
Member - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Protein-protein interactions play important roles in most ce...» Protein-protein interactions play important roles in most cellular processes. Proteins interact through chemical and structural complementarity of their mutual binding sites. Amino acids found in physical proximity form non-covalent interactions that stabilize the complex. Here we studied the evolution of PPI interfaces applying directed in vitro evolution on a random TEM library expressed on yeast surface. Our study focused on two specific questions: 1) How plastic is a well-defined PPI interface? For that purpose the TEM library was softly selected against its high affinity binder BLIP and analyzed by deep sequencing. 2) Is it possible to evolve new PPIs? Here the monomeric TEM library was selected against TEM-WT and other proteins to create new binders. Our results show that PPI interfaces are plastic and easily formed, hence evolution must actively act to prevent promiscuous protein binding. One mechanism which seems to be applied by nature for that purpose is keeping wild type proteins below their potential stability in a way that they are easily destabilized upon mutation. -
Date:07TuesdayMarch 2017Lecture
Mechanisms of calcium accumulation and mineralization in coccolithophores
More information Time 11:15 - 11:15Location Ullmann Building of Life SciencesLecturer Prof. Assaf Gal
Dept. of Plant and Environmental Sciences, The Weizmann Institute of ScienceOrganizer Department of Plant and Environmental SciencesContact -
Date:07TuesdayMarch 2017Lecture
MCB - Students seminar
More information Time 12:15 - 12:15Title TBALocation Wolfson Building for Biological ResearchOrganizer Department of Molecular Cell BiologyContact -
Date:07TuesdayMarch 2017Lecture
MIF as a therapeutic candidate for amyotrophic lateral sclerosis
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Adrian Israelson
Dept of Physiology and Cell Biology Ben-Gurion University of the Negev, Be'er-ShevaOrganizer Department of Brain SciencesContact -
Date:07TuesdayMarch 2017Lecture
“scientific paper writing - a survival guide”
More information Time 15:00 - 16:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Bodil Holst
University of BergenOrganizer Faculty of ChemistryContact Abstract Show full text abstract about author of the book “scientific paper writing - a survival gu...» author of the book “scientific paper writing - a survival guide” -
Date:08WednesdayMarch 2017Lecture
G-INCPM-Special Seminar - Prof. Yaron Shav-Tal, Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University - "Quantifying mRNA transcription on single alleles in single cells"
More information Time 11:00 - 12:15Location Nancy and Stephen Grand Israel National Center for Personalized MedicineLecturer Prof. Yaron Shav-Tal
Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan UniversityOrganizer Faculty of BiochemistryContact Abstract Show full text abstract about I will describe approaches used to follow and quantify trans...» I will describe approaches used to follow and quantify transcription kinetics from single genes in fixed and living cells, using single-molecule RNA FISH and live-cell imaging. These studies have allowed us to examine transcription at high resolution during the cell cycle and to reveal new levels of regulation. We have also generated a method to tag endogenous genes on the mRNA and protein levels, and this has allowed us to use RNA FISH to differentiate between the transcriptional activity of various alleles of the same gene in single cells, to characterize a cellular response to stress, and to screen for compounds that interfere with the stress response. -
Date:08WednesdayMarch 2017Lecture
"Aspects of Accidental Symmetries"
More information Time 11:00 - 11:00Location Weismann AquariumLecturer Marco Nardecchia
CERNOrganizer Department of Particle Physics and AstrophysicsContact Abstract Show full text abstract about Motivated by the lack of signals of New Physics in indirect ...» Motivated by the lack of signals of New Physics in indirect searches and by the fact that the SM posses various accidental and approximate symmetries, I will talk about extensions at the electroweak scale of the SM that automatically preserve such symmetries. I will finally comment about cosmological as well as phenomenological implications of such a framework. -
Date:08WednesdayMarch 2017Lecture
Root-bacteria chemical interactions in the microfluidic lens
More information Time 11:00 - 11:00Location Ullmann Building of Life SciencesLecturer Hassan Massalha
Prof. Asaph Aharoni's Lab, Dept. of Plant and Environmental Sciences, The Weizmann Institute of ScienceOrganizer Department of Plant and Environmental SciencesContact -
Date:08WednesdayMarch 2017Lecture
Electroweak precision observables in Composite Higgs models: how robust are they?"
More information Time 13:00 - 13:00Location Weismann AquariumLecturer Diptimoy Ghosh, WIS Organizer Department of Particle Physics and AstrophysicsContact -
Date:08WednesdayMarch 2017Cultural Events
The Israel Camerata Jerusalem - Mozart and More
More information Time 20:00 - 20:00Location Michael Sela AuditoriumHomepage Contact -
Date:09ThursdayMarch 2017Lecture
Magnetic Resonance Seminar
More information Time 09:30 - 09:30Title MRI and NMR in 1T permanent magnets: challenges and solutionsLocation Gerhard M.J. Schmidt Lecture HallLecturer Dr. Peter Bendel
CTO, Aspect ImagingOrganizer Department of Chemical and Biological PhysicsContact -
Date:09ThursdayMarch 2017Lecture
Molecular semiconductors for LEDs and solar cells: designing around the Coulomb interaction
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Prof. Richard Friend
Cavendish Laboratory, Cambridge UniversityOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:09ThursdayMarch 2017Colloquia
Physics Colloquium- canceled
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesOrganizer Faculty of PhysicsContact Abstract Show full text abstract about There will be no Physics Colloquium On Thursday, March, 9...» There will be no Physics Colloquium
On Thursday, March, 9th,2017 -
Date:09ThursdayMarch 2017Lecture
Parametric control of actions and its feed-forward nature
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Anatol G. Feldman
Dept of Neuroscience, University of Montreal and The Centre for Interdisciplinary Research in Rehabilitation, MontrealOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The activity of different descending systems can be de-corre...» The activity of different descending systems can be de-correlated from kinematic and kinetic variables describing the motor outcome to reveal that these systems are responsible for parametric shifts in balance in the interaction between the organism and environment. Such shifts also pre-determine the origin (referent) points of spatial frames reference in which actions are produced. Parametric (referent) control can be identified at any level of action production, from the level of a single motorneuron to the level involving motoneurons of multiple muscles of the body. -
Date:10FridayMarch 2017Cultural Events
Nathan's freinds - From Paris with love
More information Time 20:00 - 20:00Location Michael Sela AuditoriumContact -
Date:12SundayMarch 2017Lecture
Motor abundance, compensation and adaptability for upper limb movements after stroke
More information Time 11:00 - 11:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Mindy F. Levin
School of Physical and Occupational Therapy McGill University, Montreal, CanadaOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Following a stroke or damage to the central nervous system, ...» Following a stroke or damage to the central nervous system, deficits in motor planning and execution may ensue, leading to a reduced capacity to use the affected upper limb to meaningfully interact with objects in the environment. A framework of disordered motor control based on reduced threshold control will be presented and considered together with cognitive and perceptual deficits underlying movement deficits.