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ינואר 01, 2013
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Date:06שנימרץ 2017סימפוזיונים
"Surface studies and matter wave optics experiments with neutral helium beams"
More information שעה 11:00 - 12:15מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Bodil Holst
University of Bergenמארגן הפקולטה לכימיהצרו קשר -
Date:06שנימרץ 2017הרצאה
Metabolic regulation of normal and leukaemia stem cells: the role of reactive oxygen species, mitochondria transfer and nitric oxide
More information שעה 14:00 - 15:00כותרת Cancer Research Clubמיקום בניין ע"ש מקס ולילאן קנדיוטימרצה Prof. Tsvee Lapidot
Dept. of Immunology, Weizmann Instituteמארגן המחלקה לאימונולוגיה ורגנרציה ביולוגיתצרו קשר תקציר Show full text abstract about Bone marrow (BM) retained blood forming stem cells are prote...» Bone marrow (BM) retained blood forming stem cells are protected from DNA damaging agents including chemotherapy to prevent lethal infections and hematology failure. Stem cell chemotherapy resistance, requires dynamic interactions with BM stromal and endothelial cells and involves metabolic regulation of ROS, mitochondria transfer, and inhibition of NO. Leukemic stem cells initiate and maintain the disease and are the major target for clinical chemotherapy treatment. These malignant stem cells also reside in the BM and their chemotherapy resistance can lead to lethal leukemia relapse. Metabolic regulation of normal and leukemic stem cells in the bone marrow will be discussed. -
Date:06שנימרץ 2017אירועי תרבות
דירה להשכיר - הצגת ילדים
More information שעה 17:30 - 17:30מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:07שלישימרץ 2017הרצאה
How did the first protein form(s) evolve?
More information שעה 10:00 - 10:30מיקום בניין וולפסון למחקר ביולוגימרצה Dr. Maria Luisa Romero Romero
Member - Dept. of Biomolecular Sciences-WISמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Short functional peptides are likely to have served as cruci...» Short functional peptides are likely to have served as crucial intermediates between a primordial RNA world and the extant protein world. Our working hypothesis is that relics of these ancestral peptides still exist in the form of key motifs in active sites of present-day proteins. One such motif, probably the most obvious one, is the P-loop (Walker A motif) that typically binds the transferred phosphate moiety of ATP. Overall, our results show that P-loop NTPases could have emerged from a relatively short P-loop containing peptide and that self-assembly played a key role in endowing biochemical function despite limited size and complexity. -
Date:07שלישימרץ 2017הרצאה
Designed by Nature: Reduced Protein Stability Prevents Promiscuous Protein Binding The Case of TEM1-β-Lactamase
More information שעה 10:30 - 11:00מיקום בניין וולפסון למחקר ביולוגימרצה Ruth Khait
Member - Dept. of Biomolecular Sciences-WISמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Protein-protein interactions play important roles in most ce...» Protein-protein interactions play important roles in most cellular processes. Proteins interact through chemical and structural complementarity of their mutual binding sites. Amino acids found in physical proximity form non-covalent interactions that stabilize the complex. Here we studied the evolution of PPI interfaces applying directed in vitro evolution on a random TEM library expressed on yeast surface. Our study focused on two specific questions: 1) How plastic is a well-defined PPI interface? For that purpose the TEM library was softly selected against its high affinity binder BLIP and analyzed by deep sequencing. 2) Is it possible to evolve new PPIs? Here the monomeric TEM library was selected against TEM-WT and other proteins to create new binders. Our results show that PPI interfaces are plastic and easily formed, hence evolution must actively act to prevent promiscuous protein binding. One mechanism which seems to be applied by nature for that purpose is keeping wild type proteins below their potential stability in a way that they are easily destabilized upon mutation. -
Date:07שלישימרץ 2017הרצאה
Mechanisms of calcium accumulation and mineralization in coccolithophores
More information שעה 11:15 - 11:15מיקום בניין אולמן למדעי החייםמרצה Prof. Assaf Gal
Dept. of Plant and Environmental Sciences, The Weizmann Institute of Scienceמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:07שלישימרץ 2017הרצאה
MCB - Students seminar
More information שעה 12:15 - 12:15כותרת TBAמיקום בניין וולפסון למחקר ביולוגימארגן המחלקה לביולוגיה מולקולרית של התאצרו קשר -
Date:07שלישימרץ 2017הרצאה
MIF as a therapeutic candidate for amyotrophic lateral sclerosis
More information שעה 12:30 - 12:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Adrian Israelson
Dept of Physiology and Cell Biology Ben-Gurion University of the Negev, Be'er-Shevaמארגן המחלקה למדעי המוחצרו קשר -
Date:07שלישימרץ 2017הרצאה
“scientific paper writing - a survival guide”
More information שעה 15:00 - 16:15מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Bodil Holst
University of Bergenמארגן הפקולטה לכימיהצרו קשר תקציר Show full text abstract about author of the book “scientific paper writing - a survival gu...» author of the book “scientific paper writing - a survival guide” -
Date:08רביעימרץ 2017הרצאה
G-INCPM-Special Seminar - Prof. Yaron Shav-Tal, Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University - "Quantifying mRNA transcription on single alleles in single cells"
More information שעה 11:00 - 12:15מיקום המרכז הישראלי הלאומי לרפואה מותאמת אישית על-שם ננסי וסטיבן גרנדמרצה Prof. Yaron Shav-Tal
Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan Universityמארגן הפקולטה לביוכימיהצרו קשר תקציר Show full text abstract about I will describe approaches used to follow and quantify trans...» I will describe approaches used to follow and quantify transcription kinetics from single genes in fixed and living cells, using single-molecule RNA FISH and live-cell imaging. These studies have allowed us to examine transcription at high resolution during the cell cycle and to reveal new levels of regulation. We have also generated a method to tag endogenous genes on the mRNA and protein levels, and this has allowed us to use RNA FISH to differentiate between the transcriptional activity of various alleles of the same gene in single cells, to characterize a cellular response to stress, and to screen for compounds that interfere with the stress response. -
Date:08רביעימרץ 2017הרצאה
"Aspects of Accidental Symmetries"
More information שעה 11:00 - 11:00מיקום Weismann Aquariumמרצה Marco Nardecchia
CERNמארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהצרו קשר תקציר Show full text abstract about Motivated by the lack of signals of New Physics in indirect ...» Motivated by the lack of signals of New Physics in indirect searches and by the fact that the SM posses various accidental and approximate symmetries, I will talk about extensions at the electroweak scale of the SM that automatically preserve such symmetries. I will finally comment about cosmological as well as phenomenological implications of such a framework. -
Date:08רביעימרץ 2017הרצאה
Root-bacteria chemical interactions in the microfluidic lens
More information שעה 11:00 - 11:00מיקום בניין אולמן למדעי החייםמרצה Hassan Massalha
Prof. Asaph Aharoni's Lab, Dept. of Plant and Environmental Sciences, The Weizmann Institute of Scienceמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:08רביעימרץ 2017הרצאה
Electroweak precision observables in Composite Higgs models: how robust are they?"
More information שעה 13:00 - 13:00מיקום Weismann Aquariumמרצה Diptimoy Ghosh, WIS מארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהצרו קשר -
Date:08רביעימרץ 2017אירועי תרבות
הקאמרטה הישראלית ירושלים - לא רק מוצרט
More information שעה 20:00 - 20:00מיקום אודיטוריום מיכאל סלעדף בית צרו קשר -
Date:09חמישימרץ 2017הרצאה
Magnetic Resonance Seminar
More information שעה 09:30 - 09:30כותרת MRI and NMR in 1T permanent magnets: challenges and solutionsמיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Dr. Peter Bendel
CTO, Aspect Imagingמארגן המחלקה לפיזיקה כימית וביולוגיתצרו קשר -
Date:09חמישימרץ 2017הרצאה
Molecular semiconductors for LEDs and solar cells: designing around the Coulomb interaction
More information שעה 11:00 - 12:00מיקום בניין פרלמן למדעי הכימיהמרצה Prof. Richard Friend
Cavendish Laboratory, Cambridge Universityמארגן המחלקה לכימיה מולקולרית ולמדע חומריםצרו קשר -
Date:09חמישימרץ 2017סימפוזיונים
Physics Colloquium- canceled
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about There will be no Physics Colloquium On Thursday, March, 9...» There will be no Physics Colloquium
On Thursday, March, 9th,2017 -
Date:09חמישימרץ 2017הרצאה
Parametric control of actions and its feed-forward nature
More information שעה 12:30 - 12:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Anatol G. Feldman
Dept of Neuroscience, University of Montreal and The Centre for Interdisciplinary Research in Rehabilitation, Montrealמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about The activity of different descending systems can be de-corre...» The activity of different descending systems can be de-correlated from kinematic and kinetic variables describing the motor outcome to reveal that these systems are responsible for parametric shifts in balance in the interaction between the organism and environment. Such shifts also pre-determine the origin (referent) points of spatial frames reference in which actions are produced. Parametric (referent) control can be identified at any level of action production, from the level of a single motorneuron to the level involving motoneurons of multiple muscles of the body. -
Date:10שישימרץ 2017אירועי תרבות
החברים של נתן -מפריס באהבה
More information שעה 20:00 - 20:00מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:12ראשוןמרץ 2017הרצאה
Motor abundance, compensation and adaptability for upper limb movements after stroke
More information שעה 11:00 - 11:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Mindy F. Levin
School of Physical and Occupational Therapy McGill University, Montreal, Canadaמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Following a stroke or damage to the central nervous system, ...» Following a stroke or damage to the central nervous system, deficits in motor planning and execution may ensue, leading to a reduced capacity to use the affected upper limb to meaningfully interact with objects in the environment. A framework of disordered motor control based on reduced threshold control will be presented and considered together with cognitive and perceptual deficits underlying movement deficits.