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April 30, 2015

  • Date:27TuesdayOctober 2015

    Contemplating Music "Humor" - in Hebrew

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    Time
    16:30 - 17:30
    Title
    The Israel Camerata Jerusalem
    Location
    Michael Sela Auditorium
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    Cultural Events
  • Date:28WednesdayOctober 2015

    Proper astronomical image processing - Solving the problems of image coaddition and image subtraction

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    Time
    11:15 - 12:15
    Location
    Dannie N. Heineman Laboratory
    LecturerDr. Barak Zackay
    Organizer
    Nella and Leon Benoziyo Center for Astrophysics
    Contact
    AbstractShow full text abstract about While co-addition and subtraction of astronomical images sta...»
    While co-addition and subtraction of astronomical images stand at the heart of observational astronomy,
    the existing solutions for them lack rigorous argumentation, are not achieving maximal sensitivity and are often slow.
    Moreover, there is no widespread agreement on how they should be done, and often different methods are used for different scientific applications.
    I am going to present rigorous solutions to these problems, deriving them from the most basic statistical principles.
    These solutions are proved optimal, under well defined and practically acceptable assumptions,
    and in many cases improve substantially the performance of the most basic operations in astronomy.
    For coaddition, we present a coadd image that under the assumption of spatially uniform noise is:
    a) sufficient for any further statistical decision or measurement on the entire data set.
    b) improves both survey speed (by 5-20%) and effective spatial resolution of astronomical surveys
    c) improves substantially imaging through turbulence applications such as lucky imaging and speckle interferometry
    d) much faster than many of the currently used coaddition solutions.

    For subtraction, we present a subtraction image that is:
    a) Free of subtraction artifacts, hopefully relieving the transient detection pipelines from machine learning algorithms and human scanning.
    b) optimal for transient detection under the assumption of spatially uniform noise.
    c) sufficient for any further statistical decision including the identification of cosmic rays and other image artifacts.
    d) orders of magnitude faster than existing subtraction methods.
    e) allows accurate statistical analysis of the resulting subtraction image, allowing exact knowledge of a transients significance.

    As you will see, the derivation of these methods requires only structured, basic and predictable statistical tools.
    Therefore the same could be easily done for many other problems in observational astronomy
    Lecture
  • Date:29ThursdayOctober 2015

    Affinity and Biorecognition

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    Time
    All day
    Location
    The David Lopatie Conference Centre
    Chairperson
    Ed Bayer
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    Conference
  • Date:29ThursdayOctober 2015

    DNA Damage Responses and Mutations in Stem Cell Aging

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    Time
    10:00 - 10:00
    Title
    DNA Damage Responses and Mutations in Stem Cell Aging
    Location
    Camelia Botnar Building
    LecturerProf. Lenhard Rudolph, MD
    Scientific Director of Leibniz Institute for Age Research
    Organizer
    Department of Molecular Cell Biology
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    Lecture
  • Date:29ThursdayOctober 2015

    21st Century Alchemy: Engineered Topological Phenomena in Periodically Driven Systems

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerProf. Erez Berg
    WIS
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about Periodically driven quantum systems, such as semiconductors ...»
    Periodically driven quantum systems, such as semiconductors subject to light and cold atoms in optical lattices, provide a novel and versatile platform for realizing topological phenomena. Some of these are analogs of topological insulators and superconductors, attainable also in static systems; others are unique to the periodically driven case. I will describe how periodic driving, disorder, and interactions in a quantum many-body system can conspire to give rise to robust non-equilibrium steady states, with no analogues in static systems.
    Colloquia
  • Date:01SundayNovember 2015

    Chewing rocks – physiology and mechanisms of iron-oxidizing bacteria and their habitats on modern and ancient earth

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    Time
    11:00 - 11:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerAndreas Kappler
    University of Tubingen
    Organizer
    Department of Earth and Planetary Sciences
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    Lecture
  • Date:01SundayNovember 2015

    Switching miRNAs on and off on an evolutionary and physiological time scales

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    Time
    13:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerYonit Hoffman
    Tzachi Pilpel's group, Dept. of Molecular Genetics
    Organizer
    Department of Molecular Genetics
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    Lecture
  • Date:01SundayNovember 2015

    The molecular and phenotypic landscape of host-pathogen interactions

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    Time
    14:00 - 15:00
    Location
    Raoul and Graziella de Picciotto Building for Scientific and Technical Support
    LecturerProf. Roi Avraham
    Organizer
    Department of Immunology and Regenerative Biology
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    Lecture
  • Date:02MondayNovember 201505ThursdayNovember 2015

    SAAC Reviews

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    Time
    All day
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    Academic Events
  • Date:02MondayNovember 2015

    Quantitative fate mapping of hematopoiesis in situ

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    Time
    09:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Organizer
    Department of Systems Immunology
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    Lecture
  • Date:03TuesdayNovember 2015

    Eukaryotic gene regulation as frequency modulation

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    Time
    10:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Organizer
    Department of Systems Immunology
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    Lecture
  • Date:03TuesdayNovember 2015

    Agonizing minds: The Monod-Jacobs explorations of gene and enzyme regulation

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    Time
    10:00 - 11:00
    Location
    Wolfson Building for Biological Research
    LecturerProf. Dan Tawfik
    Dept.of Biological Chemistry-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about This seminar regards the history of science, and specificall...»
    This seminar regards the history of science, and specifically the discoveries of the molecular mechanisms of gene and enzyme regulation by Jacques Monod (1910-1976) and Francois Jacobs (1920-2013).

    The physiological adaptation of microorganism to catabolize a given sugar upon its appearance in the growth medium has been noticed in yeast around 1900. Yet it took nearly half a century, and the relentless minds of Jacques Monod, later joined by Francois Jacob, to unravel the molecular mechanisms that underlie this adaption, or induction as it became known. The anxious, agonizing minds of Jacobs and Monod, their obsession with ‘big questions’, combined with experimental ingenuity, led to the textbook paradigms of the Lac operon and gene regulation, and of allosteric enzyme regulation.



    Lecture
  • Date:03TuesdayNovember 2015

    From design-by-evolution to evolution-by-design – the case of CLL

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    Time
    13:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerDr. Dan Landau
    Broad Institute, Cambridge, MA, USA
    Organizer
    Department of Molecular Genetics
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    Lecture
  • Date:03TuesdayNovember 2015

    Looking at proteins in live cells at atomic resolution: From Science Fiction to Science Reality

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    Time
    14:00 - 15:00
    Location
    Raoul and Graziella de Picciotto Building for Scientific and Technical Support
    LecturerPhilip Selenko
    Organizer
    Department of Immunology and Regenerative Biology
    Contact
    Lecture
  • Date:03TuesdayNovember 2015

    Transmission of mechanical force: the role of the AmotL2 /cadherin complex in normal development and cancer

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    Time
    14:00 - 14:00
    Location
    Wolfson Auditorium
    LecturerProfessor Lars Holmgren
    Department of Oncology-Pathology, Cancer Center Karolinska Institute, Stockholm, Sweden
    Organizer
    Department of Molecular Cell Biology
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    Lecture
  • Date:04WednesdayNovember 2015

    Developmental axon pruning requires destabilization of cell adhesion by JNK signaling

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    Time
    10:00 - 10:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerProf. Oren Schuldiner
    Dept. of Molecular Cell Biology, WIS
    Contact
    Lecture
  • Date:04WednesdayNovember 2015

    G-INCPM-Special Seminar - Prof. Miguel Weil, Head of the Cell Screening Facility for Personalized Medicine, Department of Cell Research and Immunology, Tel-Aviv Univ. - Novel approach for Personalized Medicine of rare diseases

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    Time
    11:00 - 12:30
    Location
    Nancy and Stephen Grand Israel National Center for Personalized Medicine
    LecturerProf. Miguel Weil
    Head of the Cell Screening Facility for Personalized Medicine, Department of Cell Research and Immunology, Tel-Aviv Univ.
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Personalized medicine aims the tailoring of strategies to de...»
    Personalized medicine aims the tailoring of strategies to detect, treat, and prevent disease based on an individual’s genetic fingerprint or makeup. Although several advances have been made in molecular profiling technologies to obtain and analyze vast amount of personal information, this technologies has yet to prove their use for drug-personalized treatment.
    We have developed a novel approach that could solve this existing gap between the identification of disease biomarkers within the acquired personalized biological data and their potential for drug-personalized treatment. We use image based high content analysis (HCA) to identify the disease phenotype in cells from patients with neurodegenerative and rare diseases. This technology obtains the personal biological information from multiple images taken from thousands of cells isolated from skin biopsies of patients allowing us to identify specific disease signatures or disease phenotypes based on the ! individual’s cell biology. These disease signatures will enable us to screen thousands of drugs on patient cells and to isolate potential drugs for personalized treatment. This approach will contribute a great deal to the evolving field of personalized medicine in general and to the field of diagnosis and treatment of incurable neurodegenerative and rare diseases. The Cell Screening Facility for Personalized Medicine (CSFPM) which is part of the new Blavatnik Center for Drug Development (BCDD) at TAU, aims to find potential drugs for treatment of rare diseases like Amyotrophic Lateral Sclerosis (ALS), Familial Dysautonomia (FD), Duchenne Muscular Dystrophy (DMD), Adult Polyglucosan Body Disease (APBD) and others.
    Lecture
  • Date:04WednesdayNovember 2015

    Dira Lehaskir - Children's Theatre

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    Time
    17:30 - 19:00
    Location
    Michael Sela Auditorium
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    Cultural Events
  • Date:05ThursdayNovember 2015

    Magnetic Resonance Seminar

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    Time
    09:30 - 09:30
    Title
    In-cell NMR and EPR methods to derive high-resolution insights into the structure(s) and dynamics of a human amyloid protein in differentmammalian cell types
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Phil Selenko
    Leibniz Institute of Molecular Pharmacology (FMP Berlin)
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about Abstract: Here, I present an overview of the various NMR and...»
    Abstract: Here, I present an overview of the various NMR and EPR methods that we used
    to derive the first full-scale atomic-resolution description of an intrinsically disordered
    human amyloid protein in five different mammalian cell types, including cells of neuronal
    and non-neuronal origins. Furthermore, I present an outlook towards using these tools to
    studying intracellular aggregation processes and preliminary data on different aggregate
    structures that form in response to cellular stress conditions.
    Lecture
  • Date:05ThursdayNovember 2015

    Clathrin-coated pits mature by continuous bending and remodeling of the coat

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    Time
    10:00 - 10:00
    Location
    Max and Lillian Candiotty Building
    LecturerProf. Ori Avinoam
    Organizer
    Department of Immunology and Regenerative Biology
    Contact
    Lecture

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