Pages

February 18, 2016

  • Date:29TuesdayMarch 2016

    Excitation-inhibition interplay in the thalamocortical pathway controls timing of motor actions

    More information
    Time
    12:30 - 12:30
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerProf. Yifat Prut
    Dept of Medical Neurobiology, IMRIC and ELSC,The Hebrew University, Hadassah Medical School, Jerusalem
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Proper performance of voluntary movements requires the integ...»
    Proper performance of voluntary movements requires the integration of both spatial and temporal information about the ensuing movements. The timing of actions is often considered to be dictated by cerebellar output that is relayed to the motor cortex via the motor thalamus. We investigated the mechanisms by which the cerebellar-thalamo-cortical (CTC) system controls temporal properties of motor cortical activity.
    We found that in primates the CTC pathway efficiently recruits motor cortical neurons in primary motor and premotor areas. Cortical responses to CTC activation were dominated by prolonged inhibition mediated by a feedforward mechanism. We further found that cortical cells that integrated CTC input fired transiently and synchronously at movement onset, when the timing of action is dictated. Moreover, when preventing the flow of information in the pathway the phasic firing at movement onset was reduced, but the preferred direction of the cells remained unchanged. These changes in neural firing were correlated with altered motor behavior: the monkeys were able to perform the task but with increased reaction and movement times.
    These results suggest that the CTC system affects cortical firing by changing the excitation-inhibition balance at movement onset in an extensive network of TC-activated motor cortical neurons. In this manner, the temporal pattern of neural firing is shaped, and firing across groups of neurons is synchronized to generate transiently enhanced firing.
    Lecture
  • Date:29TuesdayMarch 2016

    Movie - WINDING about Hayarkon river

    More information
    Time
    16:30 - 18:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:30WednesdayMarch 2016

    ACTION NOW

    More information
    Time
    10:00 - 17:00
    Title
    WANDERING SEMINAR
    Location
    Jacob Ziskind Building
    Organizer
    Faculty of Mathematics and Computer Science
    Contact
    Lecture
  • Date:30WednesdayMarch 2016

    Small Molecule-induced Cell Fate Reprogramming

    More information
    Time
    11:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerProf. HongKui Deng
    Director of Stem Cell Research Center, Peking University, Beijing, China
    Contact
    Lecture
  • Date:31ThursdayMarch 2016

    Cultural changes during the Ghassulian period

    More information
    Time
    All day
    Location
    The David Lopatie Conference Centre
    Chairperson
    Elisabetta Boaretto
    Contact
    Conference
  • Date:31ThursdayMarch 2016

    "Nanostructured Polymer Hybrids"

    More information
    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Ulrich B. Wiesner
    Cornell University
    Organizer
    Faculty of Chemistry
    Contact
    AbstractShow full text abstract about Solutions to global problems including energy conversion and...»
    Solutions to global problems including energy conversion and storage, clean water and human health require increasingly complex, multi-component hybrid materials with unprecedented control over composition, structure, and order down to the nanoscale. This talk will give examples for the rational design of novel functional hybrid materials starting from nanoparticles and moving into their composites with polymers. These materials are often based on the self-assembly of block copolymers as structure directing molecules for polymer-inorganic hybrid materials. Discussion will include formation of synthetic porous materials with amorphous, polycrystalline, and epitaxially grown single-crystal structures. Experiments will be compared to theoretical predictions to provide physical insights into formation principles. The aim of the described work is to understand the underlying fundamental chemical, thermodynamic and kinetic formation principles enabling generalization of results over a wide class of materials systems. Examples will cover the formation of hierarchical structures at equilibrium as well as via processes far away from equilibrium. Targeted applications of the prepared systems will include the development of fluorescent hybrid probes for nanomedicine, nanostructured hybrids for energy conversion and storage devices, as well as the formation of first self-assembled superconductors.
    Colloquia
  • Date:31ThursdayMarch 2016

    On the Discovery of Super-heavy Nuclei

    More information
    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerSigurd Hofmann
    GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany and Institute for Physics, Goethe University, Frankfurt, Germany
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about Scientifically based attempts to synthesize new elements bey...»
    Scientifically based attempts to synthesize new elements beyond uranium started in the middle of the 1930's, when the atomic model was established and the constituents of the atomic nucleus, protons and neutrons, were known. In this talk I will present a short history from early searches for ‘trans-uraniums’ up to the production and safe identification of shell-stabilized ‘Super-Heavy Nu-clei (SHN)’. The nuclear shell model reveals that these nuclei should be located in a region with closed shells for the protons at Z = 114, 120 or 126 and for the neutrons at N = 184. The outstanding aim of experimental investigations is the exploration of this region of spherical SHN. Experimental methods are described, which allowed for the identification of these nuclei. Systematic studies of heavy ion reactions for the synthesis of SHN revealed production cross-sections which reached values down to one picobarn and even below for the heaviest species. The systematics of measured cross-sections can be understood only on the basis of relatively high fission barriers as predicted for nuclei in and around the island of SHN. A key role in answering some of the open questions plays the synthesis of isotopes of element 120. Attempts aiming for synthesizing this element at the velocity filter SHIP will be reported. Finally, plans are presented for the further development of the experimental set-ups. Efforts performed at various laboratories will eventually reveal the change of shell strength as function of proton and neutron number, the location of the most stable nuclei and how long their lifetime will be, the optimum method of their production, and, possibly, the existence of nucleonic arrangements and shapes, which are presently still objects of speculation.


    Colloquia
  • Date:31ThursdayMarch 2016

    Spotlight on Science: Aspects of faith and territories

    More information
    Time
    12:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerNira Pereg
    Video Artist
    Organizer
    Department of Life Sciences Core Facilities
    Contact
    Lecture
  • Date:31ThursdayMarch 2016

    Ori Hezkiah - Stand up

    More information
    Time
    21:30 - 21:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:03SundayApril 2016

    Deciphering Jupiter's internal flow using the Juno gravity measurements and an adjoint based dynamical model

    More information
    Time
    11:00 - 11:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerDr. Eli Galanti
    Earth and Planetary Sciences Weizmann Institute of Science
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    Lecture
  • Date:03SundayApril 2016

    To be announced

    More information
    Time
    13:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerSantosh Kumar
    Adi Kimchi's group, Dept. of Molecular Genetics, WIS
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:04MondayApril 2016

    G-INCPM International Workshop 2016

    More information
    Time
    All day
    Location
    The David Lopatie Conference Centre
    Chairperson
    Berta Strulovici
    Contact
    Conference
  • Date:04MondayApril 2016

    A mechanistic model of Macaque V1 cortex

    More information
    Time
    12:30 - 12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Lai-Sang Young
    Courant Institute of Mathematical Sciences New York University
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about I will report on some recent computational modeling work on ...»
    I will report on some recent computational modeling work on the Macaque visual cortex. My co-authors Bob Shapley, Logan Chariker and I have constructed a semi-realistic model of LGN-to-4Ca, the input layer to V1 in the magnocellular pathway. As with most modeling work, our aim was to understand how cortex responds to stimuli. To do that, many authors have postulated transducer functions for specific sets of stimuli. We have chosen to take a fundamentally different route: we have chosen to simulate how cortex works, by simulating cortical dynamics on the level of neuron-to-neuron interactions. Using a single network model, we have been able to reproduce as emergent phenomena a fairly comprehensive set of experimental observations, including orientation selectivity, simple and complex cells, gamma rhythms etc. Specific aims of this project were (1) to reconcile the picture of Hubel & Wiesel with the sparseness of LGN, (2) to address the extent to which cortex is driven by feedforward vs recurrent inputs, (3) to replicate and explain the diversity of neuronal responses seen in real cortex, and (4) to connect all of the above to dynamical interactions in local neuronal populations.
    Lecture
  • Date:04MondayApril 2016

    Hematopoietic Stem cells and Niches under Stress

    More information
    Time
    14:00 - 15:00
    Title
    Department of Immunology Special Guest Seminar
    Location
    Wolfson Building for Biological Research
    LecturerToshio Suda, MD, PhD
    Cancer Science Institute, National University of Singapore
    Organizer
    Department of Systems Immunology
    Contact
    Lecture
  • Date:04MondayApril 2016

    The Israel Camerata Jerusalem

    More information
    Time
    20:00 - 22:00
    Title
    Lider and other art songs
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:05TuesdayApril 2016

    Weizmann Women and Science Award 2015 – Prof. Barbara Liskov

    More information
    Time
    11:00 - 11:00
    Title
    “The Power of abstraction“
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Barbara Liskov
    Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, USA
    Contact
    Lecture
  • Date:05TuesdayApril 2016

    Ecological implications of interplant communication’

    More information
    Time
    11:15 - 11:15
    Location
    Ullmann Building of Life Sciences
    LecturerProf. Ariel Novoplansky
    Mitrani Department of Desert Ecology, Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:05TuesdayApril 2016

    Shaping neural circuits by high order synaptic interactions

    More information
    Time
    12:30 - 12:30
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerDr. Yoram Burak
    Racah Institute of Physics and Safra Center for Brain Sciences, Hebrew University of Jerusalem
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Local brain circuits are believed to exhibit diverse connect...»
    Local brain circuits are believed to exhibit diverse connectivity patterns. It is not yet clear to what extent these patterns are hard-wired genetically, or whether they arise during development under the influence of local plasticity mechanisms. In this talk I will address how spike-timing dependent plasticity (STDP) may affect the global structure of a neural circuit. We recently developed a theoretical framework that allows to address the consequences of STDP in recurrent neural circuits of arbitrary connectivity. I will show that in addition to the local influence of STDP on the synapses that connect pairs of neurons reciprocally, STDP induces non-local interactions between synapses of different neurons. These "high-order" interactions, which were neglected in previous studies, can have a pivotal influence on the global structure of a neural network in steady state. As an example, I will consider in the talk the spontaneous formation of two simple structures: wide synfire chains, in which groups of neurons project to each other sequentially, and self connected assemblies - both of which are important models for generation of structured neural dynamics. I will show that with appropriate choice of the biophysical parameters, these ordered structures can emerge autonomously under the influence of STDP and heterosynaptic competition, without exposing the neural network to any structured external inputs during learning. If time permits, I will also present briefly another recent work, concerned with the coding of an animal's position by grid cells in the entorhinal cortex.
    Lecture
  • Date:05TuesdayApril 2016

    Predicting the evolutionary pathway to virulence of an RNA virus

    More information
    Time
    14:00 - 14:00
    Location
    Helen and Milton A. Kimmelman Building
    LecturerDr. Adi Stern
    Organizer
    Department of Chemical and Structural Biology
    Contact
    Lecture
  • Date:05TuesdayApril 2016

    Cinderella - Children's Theater

    More information
    Time
    17:30 - 19:00
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events

Pages