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פברואר 18, 2016
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Date:29שלישימרץ 2016הרצאה
Excitation-inhibition interplay in the thalamocortical pathway controls timing of motor actions
More information שעה 12:30 - 12:30מיקום בניין לחקר המוח על-שם נלה וליאון בנוזיומרצה Prof. Yifat Prut
Dept of Medical Neurobiology, IMRIC and ELSC,The Hebrew University, Hadassah Medical School, Jerusalemמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Proper performance of voluntary movements requires the integ...» Proper performance of voluntary movements requires the integration of both spatial and temporal information about the ensuing movements. The timing of actions is often considered to be dictated by cerebellar output that is relayed to the motor cortex via the motor thalamus. We investigated the mechanisms by which the cerebellar-thalamo-cortical (CTC) system controls temporal properties of motor cortical activity.
We found that in primates the CTC pathway efficiently recruits motor cortical neurons in primary motor and premotor areas. Cortical responses to CTC activation were dominated by prolonged inhibition mediated by a feedforward mechanism. We further found that cortical cells that integrated CTC input fired transiently and synchronously at movement onset, when the timing of action is dictated. Moreover, when preventing the flow of information in the pathway the phasic firing at movement onset was reduced, but the preferred direction of the cells remained unchanged. These changes in neural firing were correlated with altered motor behavior: the monkeys were able to perform the task but with increased reaction and movement times.
These results suggest that the CTC system affects cortical firing by changing the excitation-inhibition balance at movement onset in an extensive network of TC-activated motor cortical neurons. In this manner, the temporal pattern of neural firing is shaped, and firing across groups of neurons is synchronized to generate transiently enhanced firing.
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Date:29שלישימרץ 2016אירועי תרבות
סרט :פתלתל על נהר הירקון - הכניסה חופשית
More information שעה 16:30 - 18:30מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:30רביעימרץ 2016הרצאה
ACTION NOW
More information שעה 10:00 - 17:00כותרת WANDERING SEMINARמיקום בניין יעקב זיסקינדמארגן הפקולטה למתמטיקה ומדעי המחשבצרו קשר -
Date:30רביעימרץ 2016הרצאה
Small Molecule-induced Cell Fate Reprogramming
More information שעה 11:00 - 11:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Prof. HongKui Deng
Director of Stem Cell Research Center, Peking University, Beijing, Chinaצרו קשר -
Date:31חמישימרץ 2016כנסים
Cultural changes during the Ghassulian period
More information שעה כל היוםמיקום מרכז כנסים על-שם דויד לופאטייושב ראש Elisabetta Boarettoצרו קשר -
Date:31חמישימרץ 2016סימפוזיונים
"Nanostructured Polymer Hybrids"
More information שעה 11:00 - 12:15מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Ulrich B. Wiesner
Cornell Universityמארגן הפקולטה לכימיהצרו קשר תקציר Show full text abstract about Solutions to global problems including energy conversion and...» Solutions to global problems including energy conversion and storage, clean water and human health require increasingly complex, multi-component hybrid materials with unprecedented control over composition, structure, and order down to the nanoscale. This talk will give examples for the rational design of novel functional hybrid materials starting from nanoparticles and moving into their composites with polymers. These materials are often based on the self-assembly of block copolymers as structure directing molecules for polymer-inorganic hybrid materials. Discussion will include formation of synthetic porous materials with amorphous, polycrystalline, and epitaxially grown single-crystal structures. Experiments will be compared to theoretical predictions to provide physical insights into formation principles. The aim of the described work is to understand the underlying fundamental chemical, thermodynamic and kinetic formation principles enabling generalization of results over a wide class of materials systems. Examples will cover the formation of hierarchical structures at equilibrium as well as via processes far away from equilibrium. Targeted applications of the prepared systems will include the development of fluorescent hybrid probes for nanomedicine, nanostructured hybrids for energy conversion and storage devices, as well as the formation of first self-assembled superconductors. -
Date:31חמישימרץ 2016סימפוזיונים
On the Discovery of Super-heavy Nuclei
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Sigurd Hofmann
GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany and Institute for Physics, Goethe University, Frankfurt, Germanyמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about Scientifically based attempts to synthesize new elements bey...» Scientifically based attempts to synthesize new elements beyond uranium started in the middle of the 1930's, when the atomic model was established and the constituents of the atomic nucleus, protons and neutrons, were known. In this talk I will present a short history from early searches for ‘trans-uraniums’ up to the production and safe identification of shell-stabilized ‘Super-Heavy Nu-clei (SHN)’. The nuclear shell model reveals that these nuclei should be located in a region with closed shells for the protons at Z = 114, 120 or 126 and for the neutrons at N = 184. The outstanding aim of experimental investigations is the exploration of this region of spherical SHN. Experimental methods are described, which allowed for the identification of these nuclei. Systematic studies of heavy ion reactions for the synthesis of SHN revealed production cross-sections which reached values down to one picobarn and even below for the heaviest species. The systematics of measured cross-sections can be understood only on the basis of relatively high fission barriers as predicted for nuclei in and around the island of SHN. A key role in answering some of the open questions plays the synthesis of isotopes of element 120. Attempts aiming for synthesizing this element at the velocity filter SHIP will be reported. Finally, plans are presented for the further development of the experimental set-ups. Efforts performed at various laboratories will eventually reveal the change of shell strength as function of proton and neutron number, the location of the most stable nuclei and how long their lifetime will be, the optimum method of their production, and, possibly, the existence of nucleonic arrangements and shapes, which are presently still objects of speculation.
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Date:31חמישימרץ 2016הרצאה
Spotlight on Science: Aspects of faith and territories
More information שעה 12:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Nira Pereg
Video Artistמארגן המחלקה לתשתיות מחקר מדעי החייםצרו קשר -
Date:31חמישימרץ 2016אירועי תרבות
אורי חזקיה - סטנד אפ
More information שעה 21:30 - 21:30מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:03ראשוןאפריל 2016הרצאה
Deciphering Jupiter's internal flow using the Juno gravity measurements and an adjoint based dynamical model
More information שעה 11:00 - 11:00מיקום בניין משפחת זוסמןמרצה Dr. Eli Galanti
Earth and Planetary Sciences Weizmann Institute of Scienceמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר -
Date:03ראשוןאפריל 2016הרצאה
To be announced
More information שעה 13:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Santosh Kumar
Adi Kimchi's group, Dept. of Molecular Genetics, WISמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:04שניאפריל 2016כנסים
G-INCPM International Workshop 2016
More information שעה כל היוםמיקום מרכז כנסים על-שם דויד לופאטייושב ראש Berta Struloviciצרו קשר -
Date:04שניאפריל 2016הרצאה
A mechanistic model of Macaque V1 cortex
More information שעה 12:30 - 12:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Lai-Sang Young
Courant Institute of Mathematical Sciences New York Universityמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about I will report on some recent computational modeling work on ...» I will report on some recent computational modeling work on the Macaque visual cortex. My co-authors Bob Shapley, Logan Chariker and I have constructed a semi-realistic model of LGN-to-4Ca, the input layer to V1 in the magnocellular pathway. As with most modeling work, our aim was to understand how cortex responds to stimuli. To do that, many authors have postulated transducer functions for specific sets of stimuli. We have chosen to take a fundamentally different route: we have chosen to simulate how cortex works, by simulating cortical dynamics on the level of neuron-to-neuron interactions. Using a single network model, we have been able to reproduce as emergent phenomena a fairly comprehensive set of experimental observations, including orientation selectivity, simple and complex cells, gamma rhythms etc. Specific aims of this project were (1) to reconcile the picture of Hubel & Wiesel with the sparseness of LGN, (2) to address the extent to which cortex is driven by feedforward vs recurrent inputs, (3) to replicate and explain the diversity of neuronal responses seen in real cortex, and (4) to connect all of the above to dynamical interactions in local neuronal populations. -
Date:04שניאפריל 2016הרצאה
Hematopoietic Stem cells and Niches under Stress
More information שעה 14:00 - 15:00כותרת Department of Immunology Special Guest Seminarמיקום בניין וולפסון למחקר ביולוגימרצה Toshio Suda, MD, PhD
Cancer Science Institute, National University of Singaporeמארגן המחלקה לאימונולוגיה מערכתיתצרו קשר -
Date:04שניאפריל 2016אירועי תרבות
הקאמרטה הישראלית ירושלים -אומנות השיר
More information שעה 20:00 - 22:00כותרת Lider and other art songsמיקום אודיטוריום מיכאל סלעצרו קשר -
Date:05שלישיאפריל 2016הרצאה
Weizmann Women and Science Award 2015 – Prof. Barbara Liskov
More information שעה 11:00 - 11:00כותרת “The Power of abstraction“מיקום אולם ע"ש דולפי ולולה אבנרמרצה Prof. Barbara Liskov
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, USAצרו קשר -
Date:05שלישיאפריל 2016הרצאה
Ecological implications of interplant communication’
More information שעה 11:15 - 11:15מיקום בניין אולמן למדעי החייםמרצה Prof. Ariel Novoplansky
Mitrani Department of Desert Ecology, Blaustein Institutes for Desert Research, Ben-Gurion University of the Negevמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:05שלישיאפריל 2016הרצאה
Shaping neural circuits by high order synaptic interactions
More information שעה 12:30 - 12:30מיקום בניין לחקר המוח על-שם נלה וליאון בנוזיומרצה Dr. Yoram Burak
Racah Institute of Physics and Safra Center for Brain Sciences, Hebrew University of Jerusalemמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Local brain circuits are believed to exhibit diverse connect...» Local brain circuits are believed to exhibit diverse connectivity patterns. It is not yet clear to what extent these patterns are hard-wired genetically, or whether they arise during development under the influence of local plasticity mechanisms. In this talk I will address how spike-timing dependent plasticity (STDP) may affect the global structure of a neural circuit. We recently developed a theoretical framework that allows to address the consequences of STDP in recurrent neural circuits of arbitrary connectivity. I will show that in addition to the local influence of STDP on the synapses that connect pairs of neurons reciprocally, STDP induces non-local interactions between synapses of different neurons. These "high-order" interactions, which were neglected in previous studies, can have a pivotal influence on the global structure of a neural network in steady state. As an example, I will consider in the talk the spontaneous formation of two simple structures: wide synfire chains, in which groups of neurons project to each other sequentially, and self connected assemblies - both of which are important models for generation of structured neural dynamics. I will show that with appropriate choice of the biophysical parameters, these ordered structures can emerge autonomously under the influence of STDP and heterosynaptic competition, without exposing the neural network to any structured external inputs during learning. If time permits, I will also present briefly another recent work, concerned with the coding of an animal's position by grid cells in the entorhinal cortex. -
Date:05שלישיאפריל 2016הרצאה
Predicting the evolutionary pathway to virulence of an RNA virus
More information שעה 14:00 - 14:00מיקום בניין הלן ומילטון קימלמןמרצה Dr. Adi Stern מארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:05שלישיאפריל 2016אירועי תרבות
סינדרלה - הצגת ילדים
More information שעה 17:30 - 19:00מיקום אודיטוריום מיכאל סלעצרו קשר
