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מרץ 17, 2016
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Date:31ראשוןמרץ 2024הרצאה
Science Literacy for All: Implications for Sustainability Education
More information שעה 13:00 - 14:00כותרת IES/SAERI- Sustainability and Energy Research Initiative Seminar Seriesמיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Prof. David Fortus
Department of Science Teaching -WISמארגן ממונה על היוזמה לחקר האנרגיה והקיימותצרו קשר -
Date:31ראשוןמרץ 2024הרצאה
Elucidating sites and mechanisms of GLP-1 action
More information שעה 15:00 - 16:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Prof. Daniel J Drucker
Mt. Sinai Hospital, Lunenfeld Tanenbaum Research Institute University of Toronto, Canada.צרו קשר -
Date:02שלישיאפריל 2024הרצאה
iSCAR Seminar
More information שעה 09:00 - 10:00מיקום בניין ע"ש מקס ולילאן קנדיוטימארגן המחלקה לאימונולוגיה ורגנרציה ביולוגיתצרו קשר -
Date:02שלישיאפריל 2024הרצאה
Studying Ageing and Neurodegenerative Brain with Quantitative MRI
More information שעה 12:30 - 13:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Aviv Mezer
ELSC for Brain Sciences The Hebrew University of Jerusalemמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Aging and neurodegeneration are associated with changes in b...» Aging and neurodegeneration are associated with changes in brain tissue at the molecular level, affecting its organization, density, and composition. These changes can be detected using quantitative MRI (qMRI), which provides physical measures that are sensitive to structural alterations. However, a major challenge in brain research is to relate physical estimates to their underlying biological sources. In this talk, I will discuss the community's efforts to use qMRI to identify biological processes that underlie changes in brain tissue. Specifically, I will highlight approaches for differentiating between changes in the concentration and composition of myelin and iron during aging. By exploring the molecular landscape of the aging and neurodegenerative brain using qMRI, we aim to gain a better understanding of these processes and potentially provide new metrics for evaluating them.
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Date:03רביעיאפריל 2024הרצאה
LS Luncheon
More information שעה 12:00 - 14:00מיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Prof. Igor Ulitsky צרו קשר -
Date:04חמישיאפריל 2024הרצאה
A guide towards recombinant protein expression
More information שעה 09:00 - 10:00כותרת Fluorescence Labeling of Cancer Cells Using Chemically Modified Bacteriaמיקום בניין ע"ש מקס ולילאן קנדיוטימרצה Dr. Tamar Unger
SPU, LSCF dept & CSB deptמארגן המחלקה לתשתיות מחקר מדעי החייםצרו קשר -
Date:04חמישיאפריל 2024הרצאה
M.Sc. Thesis Defense Seminar
More information שעה 11:00 - 12:00כותרת Characterization of bacterial genomic phenomena using long-read sequencingמיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Shai Tamari מארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:04חמישיאפריל 2024סימפוזיונים
Physics Colloquium
More information שעה 11:15 - 12:30כותרת The Rolling Stones, All Down the Lineמיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Prof. Tsvi Tlusti
UNISTמארגן המחלקה לפיזיקה של מערכות מורכבותצרו קשר תקציר Show full text abstract about Draw an arbitrary open curve on the plane and copy it multip...» Draw an arbitrary open curve on the plane and copy it multiple times to form a translationally invariant infinite trajectory. Then, incline the plane slightly and ask yourself: can one chisel a stone that will roll exactly down this infinite trajectory?
We will examine this question in practice and theory. Intriguing links to optics and quantum systems will be discussed. Bringing a tennis ball or a baseball is always recommended.
Eckmann et al. Tumbling downhill along a given curve. Am Math Soc Notices - in press.
Sobolev et al. Solid-body trajectoids shaped to roll along desired pathways. Nature 2023.
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Date:04חמישיאפריל 2024הרצאה
M.Sc. Thesis Defense Seminar
More information שעה 14:00 - 15:00כותרת Inference of environmental factors across biomes using community-wide DNA compositionמיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Tomer Antman מארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:07ראשוןאפריל 2024הרצאה
Benthic side control on the chemical composition of the ocean
More information שעה 11:00 - 11:00מיקום בניין משפחת זוסמןמרצה Zvi Steiner
GEOMAR Helmholtz Centreמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about The sediment – bottom-water interface is suggested as a key ...» The sediment – bottom-water interface is suggested as a key control on
the chemical composition of the ocean by studies of trace elements in the
ocean water-column, yet data regarding trace element fluxes and
interactions taking place in the top ten cm of abyssal sediments are
scarce. To bridge this gap, I analysed the trace and major element
composition of porewater and sediment of red-clay sediment from the
abyssal North Pacific, and hydrothermally influenced sediment from the
Mid-Atlantic Ridge. The top sediment at both study regions is aerobic,
nevertheless, there is large variability in the porewater concentrations of
many elements at the top five cm. The North Pacific red-clay sediment is
a source of cobalt, nickel, copper, arsenic, vanadium and barium to the
deep-ocean, the magnitude of these fluxes is consistent with fluxes
calculated based on the water-column distribution of most elements, and
are equivalent to the global supply of these elements by rivers. The
hydrothermally influenced sediment is a strong source of copper, zinc
and cobalt up to three km from the vent due to oxidation of sulfide
minerals. Close to the vents, the sediment is high in iron oxyhydroxides
that adsorb the oxyanions vanadate, arsenate and phosphate, acting as
a sink for these elements. The results of this study highlight the
importance of red-clay sediment in shaping the chemical composition of
the ocean, and suggest an important role for hydrothermally influenced
sediment in modulating the contributions of hydrothermal vents to ocean
biogeochemistry. -
Date:07ראשוןאפריל 2024הרצאה
The Clore Center for Biological Physics
More information שעה 13:15 - 14:30כותרת Odd Mechanical Screening: From Metamaterial to Continuum Mechanics of Disordered Solidsמיקום המאיץ ע"ש קופלר במרכז קנדה לפיסיקה גרעיניתמרצה Prof. Michael Moshe
Hebrew University in Jerusalemמארגן מרכז לפיזיקה ביולוגית עש קלורצרו קשר תקציר Show full text abstract about Holes in elastic metamaterials, defects in 2D curved crystal...» Holes in elastic metamaterials, defects in 2D curved crystals, localized plastic deformations in amorphous solids and T1 transitions in epithelial tissue, are typical realizations of stress-relaxation mechanisms in different solid-like structures, interpreted as mechanical screening.
In this talk I will present a mechanical screening theory that generalizes classical theories of solids, and introduces new moduli that are missing from the classical theories. Contrary to its electrostatic analog, the screening theory in solids is richer even in the linear case, with multiple screening regimes, predicting qualitatively new mechanical responses.
The theory is tested in different physical systems, including disordered granular solids that do not have a continuous mechanical description. These materials are shown to violate energy conservation and are best described by Odd-Screening: a screening model that does not derive from an energy function. Experiments reveal a mechanical response that is strictly different from classical solid theory and is completely consistent with our mechanical-screening theory. Finally, I will discuss the relevance of this theory to 3D solids and a new Hexatic-like state in 3D matter.
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Date:08שניאפריל 2024הרצאה
Midrasha on Groups Seminar
More information שעה 11:00 - 12:30כותרת Pushforwards of fractal measures and Diophantine approximation on self-similar setsמיקום גולדסמית-מתמטיקהמרצה Barak Weiss
TAUמארגן המחלקה למתמטיקהדף בית צרו קשר תקציר Show full text abstract about Let u be a Bernoulli measure on a fractal in R^d generated ...» Let
u be a Bernoulli measure on a fractal in R^d generated by a finite collection of contracting similarities with no rotations and with rational coefficients -
Date:08שניאפריל 2024הרצאה
Special Guest Seminar with Dr. Mark Dombrovskiy
More information שעה 13:30 - 14:30כותרת Circuit Mechanisms and Molecular Determinants of a Visuomotor Transformationמיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Mark Dombrovskiy, Ph.D.
University of California, Los Angeles; Howard Hughes Medical Instituteמארגן המחלקה לנוירוביולוגיה מולקולריתצרו קשר -
Date:08שניאפריל 2024הרצאה
Midrasha on Groups Seminar
More information שעה 14:30 - 16:00כותרת A tale of three problemsמיקום בניין יעקב זיסקינדמרצה Alex Lubotzky
Weizmannמארגן המחלקה למתמטיקהצרו קשר תקציר Show full text abstract about In this lecture three fairly elementary problems will be pre...» In this lecture three fairly elementary problems will be presented along with their history.
a. Gromov topological overlapping problem ( a.k.a. topological expanders).
b. The existence of good locally testable error-correcting codes.
c. Are all groups sofic?
While the three problems appear to be unrelated, the following talks will show that they are! The solutions of the first two will be described and a plan of attack on the third.
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Date:09שלישיאפריל 2024הרצאה
PhD defense seminar by Yotam Harnik (Prof. Shalev Itzkovitz Lab)
More information שעה 10:00 - 12:00כותרת Spatial omics of the murine and human small intestineמיקום בניין וולפסון למחקר ביולוגימרצה Yotam Harnik
Prof. Shalev Itzkovitz Labמארגן המחלקה לביולוגיה מולקולרית של התאצרו קשר -
Date:09שלישיאפריל 2024הרצאה
Inheritance of extrachromosomal DNA in cancer cells
More information שעה 10:00 - 11:00מיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Inbar Lifshits
Dept. of Biomolecular Sciences - WISמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Gene amplification contributing to tumorigenesis and thera...»
Gene amplification contributing to tumorigenesis and therapy resistance is frequently observed across many cancer types. Amplifications of up to 100’s of oncogene DNA copies can be found within chromosomes in homogenous staining regions (HSRs), or in extrachromosomal DNA (ecDNA) elements (also known as double-minutes or DMs). Amplified genes can be oncogenes such as MYCN but they can also be genes that contribute to therapy resistance. For example, amplification of dihydrofolate reductase (DHFR) can lead to methotrexate (MTX) resistance. DMs are acentric and therefore randomly segregate into daughter cells, thereby driving intra-tumor heterogeneity and increasing gene copy number under selection. Although DMs appear to tether to chromosomes during mitosis, the mechanism underlying their inheritance is not clear. Previous works described tethering based on a few observations and in a very limited manner. This work aimed to extensively examine DM tethering at specific mitosis stages. In addition, the effect of anti-cancer therapies, including DNA damaging agent and microtubule drugs was examined. Elucidating the mechanism of DM tethering could provide insight into the inheritance of other acentric DNA molecules, including DNA from viral sources.
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Date:09שלישיאפריל 2024הרצאה
Information processing in spiking networks: Converging assemblies
More information שעה 12:30 - 13:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Eran Stark
Sagol Department of Neurobiology Haifa Universityמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about How information is processed within the brain is a key quest...» How information is processed within the brain is a key question in systems neuroscience. We address the issue in spiking neuronal networks of freely moving mice. I will describe our recent findings and conclusions pertaining to three specific information processing steps: transmission, representation, and storage.
First, using feedforward optogenetic injection of white noise input to a small group of adjacent neocortical excitatory cells, we find that spike transmission to a postsynaptic cell exhibits error correction, improved precision, and temporal coding. The results are consistent with a nonlinear coincidence detection model in the postsynaptic neuron.
Second, by triggering input on animal kinematics, we create an artificial place field in an otherwise-silent pyramidal cell. In hippocampal region CA1 but not in the neocortex, artificial fields exhibit synthetic phase precession that persists for a full cycle. The local conversion of an induced rate code into an emerging phase code is compatible with a dual-oscillator interference model.
Third, by triggering input on spontaneous spiking, we impose self-terminating spike patterns in a group of presynaptic excitatory neurons and a postsynaptic cell. The precise timing of all pre- and postsynaptic spikes has a more substantial impact on long-lasting effective connectivity than that of individual cell pairs, revealing an unexpected plasticity mechanism.
We conclude that intrinsic properties of single neurons support millisecond-timescale operations, and that cortical networks are organized in functional modules which we refer to as “converging assemblies”.
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Date:09שלישיאפריל 2024הרצאה
Beyond Touch: Exploring Audible Aspects of Rodent Whisking
More information שעה 14:00 - 15:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Ben Efron PhD Thesis Defense
Advisor: Prof. Ilan Lamplמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Sensory processing is fundamental for animal adaptation and ...» Sensory processing is fundamental for animal adaptation and survival, linking them to their environments. Understanding the nervous system's integration of sensory information is crucial for comprehending behavior and cognition. This process involves integrating external cues across modalities, along with internal states, cognitive processes, and motor control, leading to complex behaviors and a nuanced understanding of the world. To facilitate research on these processes, we aimed to identify natural behaviors that produce both auditory and somatosensory stimuli, steering clear of artificial stimulus sources. We discovered that whisking, previously considered a unimodal behavior associated solely with tactile sensations, also produces sounds with distinctive acoustic features within the auditory frequency range of mice. We explored the auditory neuronal representation of sounds generated by whisking and their implications for behavioral performance. We demonstrate that sounds produced by whisking elicit diverse neuronal responses in the auditory cortex, encoding the object's identity and the mouse's whisking state, even in the absence of tactile sensations. Furthermore, we show that mice are capable of completing behavioral tasks relying solely on auditory cues generated by whisking against objects.
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Date:09שלישיאפריל 2024הרצאה
What Funga can teach us about DNA repair
More information שעה 14:00 - 15:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Dr. Shay Covo
Department of Plant Pathology and Microbiology Faculty of Agriculture, Food & Environment The Hebrew University of Jerusalemמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:10רביעיאפריל 2024סימפוזיונים
Chemical Exfoliation of Quantum Materials
More information שעה 11:00 - 12:15כותרת Special Colloquiumמיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Leslie M. Schoop
Department of Chemistry, Princeton Universityדף בית צרו קשר תקציר Show full text abstract about A large portion of research in 2D materials is limited to me...» A large portion of research in 2D materials is limited to mechanical exfoliation of van der Waals (vdW) materials. Chemical exfoliation is a relatively under-utilized route for preparing ultra-thin quantum materials, but it accesses 2D materials that cannot be obtained by mechanical “Scotch -taping.'” It is also a way to mass produce 2D materials, as mechanical taping only accesses small amounts, insufficient for industrial applications. However, chemical exfoliation comes with the drawback that it commonly introduces many defects into the 2D sheets. In this talk I will show the challenges of using chemical exfoliation for 2D quantum materials synthesis, to then introduce two systems in which the approach was successful.
I will show that we can use chemical exfoliation to synthesize large qualities of stable and magnetic monolayers of VOCl. Films of these high-quality sheets are shown to possess similar magnetic properties as the bulk crystals. I will also discuss the synthesis of a stable, aqueous ink of superconducting 1T'-WS2 monolayers. Films printed with the ink are superconducting below 7.3 K and show typical behavior of 2D superconductivity. This ink and its dried, printed version, is stable in ambient conditions. It is ideally suited for applications in flexible and printed electronics. Thus, we were able to establish that chemical exfoliation is of use for quantum materials synthesis.
