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Prof. Sima Lev
Signaling networks in cancer development and metastasisCollaboration with: Thomas Karn, Eytan Ruppin, Gordon Mills, Flavio Maina, Frank Westermann, Yosef YardenTumorigenic signaling networks in triple negative breast cancer (TNBC) subtypesCombination therapy, drug resistance, and cancer stem cellsFerroptosis and TNBC therapyReceptor Tyrosine Kinases (RTKs) (AXL, cMet, EGFR) and non-RTKs (PYK2, FAK) signaling in TNBCEpithelial-Mesenchymal Transition (EMT) & TNBC metastasis
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Prof. Doron Lancet
Bioinformatic tools for disease gene discovery, Origin of life on earthCollaboration with: Prof. Rafi Zidovetzki, University of California Riverside Prof. Philippe Schmitt-Kopplin, Helmholz Center Munich Prof. Daniel Segre, Boston UniversityGene and disease databases, Identification of disease-related mutations by next generation DNA sequencing (NGS), development of software tool for the analysis of NGS resultsComputer simulations of emergence, selection and evolution at the origin of life. Chemical kinetic modeals for mutually catalytic sets, Systems Chemistry
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Prof. Ilan Lampl
Mechanisms of tactile perception in the miceCollaboration with: Heinz Beck, Bonn Alex Binshtok, Hebrew University Nicholas Priebe, AustinConstruction of receptive field properties in the somatosensory cortexstudying functional connectivity in the barrel cortexMechanisms of adaptation in the cortexBalance excitation and inhibition in awake miceInterhemispheric correlationsMultimodal integrationNoise and synchrony in the mammalian cortexDynamic properties and mechanisms of ongoing activity in the cortexPatterns in neuronal activity in the cortex
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Prof. Meir Lahav
Solid State Chemistry in 2- and 3-dimensions. Pyroelectricity. Ice nucleation.Collaboration with: Prof Igor Lubomirsky Dr.David EhreOrganization of molecules at surfaces and interfaces;Chirality, Chemistry and the origin of lifePyroelectricity, Electrofreezing.
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Prof. Valery Krizhanovsky
The role of cellular senescence in aging and age-related diseasesCollaboration with: Uri AlonThe dynamics of senescent cells during agingThe role of senescent cells in lung fibrosis and chronic obstructive pulmonary diseaseThe role of senescent cells in Alzheimer's diseaseAnalysis of senescent cells heterogeneity on transcriptomic, proteomic and metabolomic levelsMechanisms of interaction of senescent cells with their microenvironmentInteraction of senescent cells with the immune systemCellular senescence in cancer development and treatmentCollaboration with: Ittai Ben-Porath, Hebrew UniversitySenescent cells in pre-malignant lesionsTherapy-induced senescence in cancerSenescence during embryonic developmentCollaboration with: Dr. Tal Biron-Shental, Meir HospitalSenescence in syncytiotrophoblast is disrupted during intra-uteral growth restriction (IUGR)
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