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January 12, 2015
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Date:15TuesdayOctober 2024Lecture
PhD Defense Seminar- Yael Wagner
More information Time 11:00 - 11:00Title The role of hydraulics in trees' recovery and survival from severe droughtLocation Nella and Leon Benoziyo Building for Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:29TuesdayOctober 2024Lecture
Special Guest Seminar-Dr. Tamar Ben-Shaanan
More information Time 10:00 - 11:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Tamar Ben-Shaanan
A Hairy story: Pain-sensing innervations trigger hair follicle activation and post-injury hair regenerationOrganizer Department of Molecular NeuroscienceContact Abstract Show full text abstract about Pain is a self-preservation mechanism, providing warning ind...» Pain is a self-preservation mechanism, providing warning indicators associated with tissue damage. These indicators are perceived by nociceptive peripheral innervations with the ability to signal the brain. Nociceptive innervations are also a part of the infrastructure of various organs, yet the imprint their activity has on tissue physiology remains understudied. Here, we applied chemogenetics in mice to locally activate cutaneous TRPV1 innervations in naïve skin and found it triggered accelerated anagen onset. This was preceded by a rapid apoptosis of dermal macrophages mediated by neuropeptide calcitonin gene-related peptide (CGRP), followed by an induction of Osteopontin (Spp1)-expressing dermal fibroblasts. Spp1, an extracellular matrix protein and a hair growth promoting factor, was essential for the TRPV1-triggered induction of new regenerative cycling by dormant hair follicles. Specifically, macrophages responsiveness to CGRP was required for the changes in dermal fibroblasts. Finally, we show that epidermal abrasion induced Spp1-expressing dermal fibroblasts and hair growth via a TRPV1 neuron and CGRP dependent mechanism. Collectively, these data demonstrate a role for pain facilitating innervations in coordinating a cellular mechanism that promotes hair growth and the restoration of this important mechano- and thermo-protective barrier -
Date:31ThursdayOctober 2024Lecture
Precision nanomedicine and bioengineering approaches for cancer therapy
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Ofra Benny
The School of Pharmacy Faculty of Medicine, Ein Karem The Hebrew University of JerusalemOrganizer Moross Integrated Cancer Center (MICC)Contact -
Date:03SundayNovember 2024Lecture
Forensic seismic evidence for precursory mobilization in Gaza leading to the October 7 terrorist attack
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Asaf Inbal
Tel Aviv UniversityOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about Seismic waves excited by human activity frequently obscure s...» Seismic waves excited by human activity frequently obscure signals
due to tectonic processes and are discarded as a nuisance. Seismic
noise-field analysis is, however, a powerful tool for characterizing
anthropogenic activities. In this talk, I will briefly review the
seismological fingerprints of anthropogenic noise sources and then
present a scheme devised to identify precursory activity leading to the
October 7 terrorist attack. The precursory activity in Gaza included
massive mobilization, documented by multiple media outlets. Favorable
conditions arose due to a temporary lack of anthropogenic activity in
Israel, allowing remote seismic stations to record signals due to Gaza
vehicle traffic in the early hours of Oct. 7. Seismogram analysis reveals
a widespread signal that abruptly emerged above the nighttime noise
levels about 20 minutes before the attack began. Statistical analysis
suggests the signal is highly anomalous; tests for significance indicate
that pre-attack inter-station correlations would emerge by chance only
once every 18,000 years. Tripartite array analysis was used to detect
surface waves, locate their sources, and demarcate the extent of preattack
activity within the Gaza Strip. The signal’s amplitude, frequency,
and spatiotemporal distribution appear to be aligned with vehicular
traffic emanating from the south-central region of the Gaza Strip and
extending towards its peripheries in the half-hour window preceding the
invasion. This provides valuable tactical information and suggests
embedding seismic noise-field analysis into decision-making protocols
could enhance preparedness for terrorist attacks. -
Date:04MondayNovember 2024Lecture
Midrasha on Groups Seminar
More information Time 11:15 - 13:00Title Introduction, background, and measure equivalenceLocation Elaine and Bram Goldsmith Building for Mathematics and Computer SciencesLecturer Dr. Guy Salomon
HITOrganizer Department of MathematicsContact Abstract Show full text abstract about I will mostly follow [Fu1] Section 2.1and [Fu2] Section 2 fo...» I will mostly follow [Fu1] Section 2.1and [Fu2] Section 2 for measure equivalence and [Loh2] Section 5.5 for Gromov’s dynamic criterion for quasi-isometry. I’ll also sketch the semester’s plan.
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Date:04MondayNovember 2024Lecture
Midrasha on Groups Seminar
More information Time 14:15 - 16:00Title Dynamical tilings, mean dimension, and shift embeddability for actions of amenable groupsLocation Jacob Ziskind BuildingLecturer Petr Naryshkin
Alfréd Rényi Institute of MathematicsOrganizer Department of MathematicsContact Abstract Show full text abstract about We start by introducing the problem of shift embeddability a...» We start by introducing the problem of shift embeddability and recalling the theorem of Gutman, Qiao, and Tsukamoto, which gives a satisfying answer for actions of Z^d. For actions of arbitrary amenable groups, we define property URPC (which asks for the existence of certain tilings) and show how it is useful for the question at hand. We then describe how it can often be obtained from an a priori much weaker condition. Throughout the talk, we highlight the new ideas that were required to go beyond the case of Z^d.
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Date:05TuesdayNovember 2024Lecture
Seminar for PhD thesis defense
More information Time 11:30 - 11:30Title Epithelial Tissue Regeneration by Compensatory Proliferation After Ionizing Radiation is Controlled by the Apical Caspase 9 Ortholog DroncLocation Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Tslil Braun Organizer Department of Molecular GeneticsContact -
Date:06WednesdayNovember 2024Lecture
Machine Learning and Statistics Seminar
More information Time 11:15 - 12:15Title Spectral TransformersLocation Jacob Ziskind BuildingLecturer Elad Hazan
PrincetonOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about We'll discuss a new technique for sequence modeling for...» We'll discuss a new technique for sequence modeling for prediction tasks with long range dependencies and fast inference/generation. At the heart of the method is a new formulation for state space models (SSMs) based on learning linear dynamical systems with the spectral filtering algorithm.
This gives rise to a novel sequence prediction architecture we call a spectral state space model.
Spectral state space models have two primary advantages. First, they have provable robustness properties as their performance depends on neither the spectrum of the underlying dynamics nor the dimensionality of the problem. Second, these models are constructed with fixed convolutional filters that do not require learning while still outperforming SSMs in both theory and practice.The resulting models are evaluated on synthetic dynamical systems and long-range prediction tasks of various modalities. These evaluations support the theoretical benefits of spectral filtering for tasks requiring very long range memory.
The talk will be self-contained, but here is a link to more information about spectral filtering.
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Date:06WednesdayNovember 2024Lecture
LS Luncheon
More information Time 12:00 - 14:00Title From blind spots to insights: uncovering mechanisms of epiProteome regulationLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Yifat Merbl Contact -
Date:07ThursdayNovember 2024Lecture
Stromal and Immune Plasticity Shape The Metastatic Microenvironment
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Neta Erez
Faculty of Medical & Health Sciences, Tel Aviv University.Organizer Moross Integrated Cancer Center (MICC)Contact -
Date:10SundayNovember 202413WednesdayNovember 2024International Board
the 76th Annual General meeting of the International Board 2024
More information Time All dayLocation The David Lopatie Conference CentreContact -
Date:10SundayNovember 2024Lecture
Special Guest Seminar
More information Time 11:00 - 12:00Title Central simple representations and superelliptic jacobiansLocation Jacob Ziskind BuildingLecturer Yuri Zarkhin
Pennsylvania State UniversityOrganizer Department of MathematicsContact Abstract Show full text abstract about Let p be an odd prime and f(x) a polynomial of degree at le...» Let p be an odd prime and f(x) a polynomial of degree at least 5 with complex coefficients and without repeated roots. Suppose that all the coefficients of f(x) lie in a subfield K such that:
1) K contains a primitive p-th root of unity -
Date:10SundayNovember 2024Lecture
Late Oxygenation of Marine Environments Revealed by Dolomite U-Pb Dating
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Uri Ryb
Hebrew University of JerusalemOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about causal relationships between evolution and oxygenation of th...» causal relationships between evolution and oxygenation of the ocean are
vigorously debated. At the heart of these uncertainties are inconsistencies
among reconstructed timelines for the rise of O2 in marine habitats. Attempts to
reconstruct the timing of marine oxygenation are often based on redox-sensitive
geochemical proxies that are prone to post-depositional alteration. Thus,
developing new proxies, more resistant to such alteration, is an important
direction forward for constraining major changes in atmospheric and marine
oxygen levels. Here, we utilize U–Pb dating in dolomite to reconstruct their
(re)crystallization ages and initial 207Pb/206Pb ratios; we find that they are
systematically younger and lower than expected, respectively. These
observations are explained by the resetting of the U–Pb system long after
deposition, followed by further evolution in a closed system. Initial 207Pb/206Pb
ratios have decreased from expected terrestrial values in the interval between
deposition and (re)crystallization, consistent with U decay, and can therefore be
used to reconstruct the initial 238U/206Pb ratios during deposition. Within our
dataset initial 238U/206Pb ratios remained low in Proterozoic to mid-Paleozoic
samples and increased dramatically in samples from the late-Paleozoic–early-
Mesozoic Eras. This rise is attributed to a higher ratio of U to Pb in seawater that
in turn influenced the fluid composition of carbonate crystallization sites.
Accordingly, we interpret the temporal shift in initial 238U/206Pb ratios to reflect
a late-Paleozoic increase in oxygenation of marine environments, corroborating
previously documented shifts in some redox-sensitive proxies. This timeline is
consistent with evolution-driven mechanisms for the oxygenation of late
Paleozoic marine environments and with suggestions that Neoproterozoic and
early Paleozoic animals thrived in oceans that overall and on long time scales
were oxygen-limited compared to the modern ocean. -
Date:10SundayNovember 2024Lecture
The Clore Center for Biological Physics
More information Time 13:15 - 14:30Title Two-Part Seminar: Predicting antibiotic resistance & AI-driven scienceLocation Nella and Leon Benoziyo Physics LibraryLecturer Prof. Roy Kishony
Technion -Faculty of Biology, Department of Bioinformatics and Systems BiologyOrganizer Clore Center for Biological PhysicsContact Abstract Show full text abstract about In this two-part talk, I will try to cover two separate line...» In this two-part talk, I will try to cover two separate lines of research: Machine learning of antibiotic resistance and AI-driven Science. In the first half, I will describe our efforts to understand and predict antibiotic resistance at the single patient level. I will describe a series of experimental-computational methodologies for following and identifying recurrent patterns in the evolution of antibiotic resistance in the lab and in the clinic. Combined with machine-learning approaches applied to electronic patient records, these tools lead to predictive diagnostics of antibiotic resistance and algorithms for personalized treatments of microbial infections. In the second part of the talk, we will shift gear and talk about AI-driven science. I will describe and demo “data-to-paper”: a platform that autonomously guides LLMs (like ChatGPT) to perform entire research cycles. Provided with data alone, data-to-paper can raise hypotheses, design research plans, write and debug analysis codes, generate and interpret results, and write complete research papers. Automatic information-tracing through the process creates manuscripts in which results, methods and data are programmatically chained. Our work thereby demonstrates a potential for AI-driven acceleration of scientific discovery while enhancing, rather than jeopardizing, traceability, transparency and verifiability. I will describe the strengths of the approach as well as limitations and challenges.
Prof. Kishony would be available to discuss with students and
postdocs after his seminar (2:15 pm - 3 pm).
So we encourage interested students and postdocs to stay after his talk!
FOR THE LATEST UPDATES AND CONTENT ON SOFT MATTER AND BIOLOGICAL PHYSICS AT THE WEIZMANN, VISIT OUR WEBSITE: https://www.biosoftweizmann.com/
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Date:11MondayNovember 2024Lecture
Midrasha on Groups Seminar
More information Time 11:15 - 12:15Title Reading Alan TuringLocation Jacob Ziskind BuildingLecturer Avi Wigderson
IAS PrincetonOrganizer Department of MathematicsContact Abstract Show full text abstract about I will discuss some well-known and less-known papers of Turi...» I will discuss some well-known and less-known papers of Turing, exemplify the scope of deep, prescient ideas he put forth, and mention follow-up work on these by the Theoretical CS community.
No special background will be assumed.
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Date:11MondayNovember 2024Lecture
Foundations of Computer Science Seminar
More information Time 11:15 - 12:15Title Reading Alan TuringLocation Jacob Ziskind BuildingLecturer Avi Wigderson
IASOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about I will discuss some well-known and less-known papers of Turi...» I will discuss some well-known and less-known papers of Turing, exemplify the scope of deep, prescient ideas he put forth, and mention follow-up work on these by the Theoretical CS community.
No special background will be assumed.
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Date:11MondayNovember 2024Lecture
PhD thesis defense- Avia Mizrachi
More information Time 14:00 - 15:00Title Phenotypic variability and cell fate determination in marine diatoms in response to environmental stressLocation Nella and Leon Benoziyo Building for Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:11MondayNovember 2024Lecture
Midrasha on Groups Seminar
More information Time 14:15 - 16:00Title High-dimensional expansion and soficity of groupsLocation Jacob Ziskind BuildingLecturer Andreas Thom
TU DresdenOrganizer Department of MathematicsContact Abstract Show full text abstract about For d≥4 and p a sufficiently large prime, we construct a lat...» For d≥4 and p a sufficiently large prime, we construct a lattice Γ≤PSp2d(ℚp), such that its universal central extension cannot be sofic if Γ satisfies some weak form of stability in permutations. In the proof, we make use of high-dimensional expansion phenomena and, extending results of Lubotzky, we construct new examples of cosystolic expanders over arbitrary finite abelian groups. This is joint with with Lukas Gohla.
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Date:12TuesdayNovember 2024Lecture
Special Guest Seminar
More information Time 11:00 - 12:00Title EV-DNA Drives Anti-Tumor Immunity and Inhibits MetastasisLocation Max and Lillian Candiotty BuildingLecturer Dr. Inbal Wortzel Organizer Department of Immunology and Regenerative BiologyContact -
Date:13WednesdayNovember 2024Lecture
Piezo2 in sensory neurons controls systemic metabolism by inhibiting adipose thermogenesis
More information Time 10:00 - 11:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Eli Zelzer
Department of Molecular GeneticsContact