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April 30, 2015
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Date:26MondayFebruary 2018Colloquia
"Bioengineered Silk Proteins for Regenerative Medicine"
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. David Kaplan
Tufts UniversityOrganizer Faculty of ChemistryContact -
Date:26MondayFebruary 2018Lecture
TBA
More information Time 14:00 - 15:00Title Special guest SeminarLocation Max and Lillian Candiotty BuildingLecturer Prof. Angel Progador
The Shraga Segal Dept. of Microbiology, Immunology and Genetics Faculty of Health Sciences, Ben-Gurion University of the NegevOrganizer Department of Immunology and Regenerative BiologyContact -
Date:26MondayFebruary 2018Lecture
Novel innate immune checkpoint reveals the need to better consider the role of receptor splice variants
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Angel Porgador
Professor and Deputy Vice President and Dean for R&D The ShragaSegal Dept. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the NegevOrganizer Department of Immunology and Regenerative BiologyContact -
Date:27TuesdayFebruary 2018Lecture
Algebraic Geometry and Representation Theory Seminar
More information Time 11:15 - 12:30Title Approximability in derived categoriesLocation Jacob Ziskind BuildingLecturer Professor Amnon Neeman
Australian National UniversityOrganizer Faculty of Mathematics and Computer Science , Department of Computer Science and Applied Mathematics , Department of MathematicsContact -
Date:27TuesdayFebruary 2018Lecture
Role of pituicytes, the resident astroglia of the neurohypophysis in neuro-vascular development
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Gil Levkowitz
Dept of Molecular Cell Biology, WISOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The hypothalamo-neurohypophyseal system (HNS) is an evolutio...» The hypothalamo-neurohypophyseal system (HNS) is an evolutionarily conserved neuroendocrine interface through which the brain regulates body homeostasis by means of releasing neuro-hormones (i.e. oxytocin and vasopressin) from the hypothalamus to the blood circulation. The basic components of the HNS are the hypothalamic axonal projections, endothelial blood vessels and astroglial-like cells, termed pituicytes. These three tissue types converge and interact at the ventral forebrain to establish an efficient neuro-vascular interface, which allows the release of neurohormones from the brain to the periphery. In contrast to BBB-containing CNS vessels, neurohypophyseal capillaries are permeable, which enables bypassing the BBB to transfer HNS hormones and blood-borne substances between brain and circulation. I will present our recent molecular and functional analysis that revealed a new role for pituicytes, in establishing a permeable neuro-vascular conduit that bypasses the BBB. -
Date:01ThursdayMarch 2018Lecture
Predator-prey interactions of nematophagous fungi and C. elegans
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Yen-Ping Hsueh
Institute of Molecular Biology, Academia Sinica, TaiwanOrganizer Department of Molecular GeneticsContact -
Date:01ThursdayMarch 2018Colloquia
Physics Colloquium
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer TBA Organizer Faculty of PhysicsContact Abstract Show full text abstract about TBA ...» TBA -
Date:04SundayMarch 2018Lecture
Developing an automatic methodology for identifying 'parent-daughter' cyclones - application for the Mediterranean Basin
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Baruch Ziv
The Open University of IsraelOrganizer Department of Earth and Planetary SciencesContact -
Date:05MondayMarch 201808ThursdayMarch 2018Conference
Frontiers in Parasitology
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Neta Regev-RudzkiHomepage -
Date:05MondayMarch 2018Lecture
Electron-beam-induced current measurements of thin-film solar cells: accessible materials/device properties and pitfalls to be avoided
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Dr. Daniel Abou Ras
Dept. of Nanoscale structures and microscopic analysis, Helmholtz Zentrum, BerlinOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Abstract: The seminar presentation will give an overview of...» Abstract:
The seminar presentation will give an overview of the various insights into materials and device properties provided by electron-beam-induced current (EBIC) measurements. It will be also outlined which specimen preparation and electron-beam parameters are necessary in order to avoid surface roughnesses or high-injection conditions, which may complicate the interpretation of the EBIC analyses.
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Date:05MondayMarch 2018Lecture
Time's Arrow, Rare Events and the Second Law of Thermodynamics
More information Time 14:15 - 14:15Lecturer Christopher Jarzynski
University of MarylandOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about As famously articulated by Sir Arthur Eddington, the second ...» As famously articulated by Sir Arthur Eddington, the second law of thermodynamics implies a directionality to the flow of time: the arrow of time points in the direction of increasing entropy. This observation is something that we understand intuitively in our everyday lives, but with nanoscale systems the situation becomes subtle due to the prominence of statistical fluctuations. At sufficiently small length and time scales, a system may behave in a manner that appears contrary to the second law. Surprisingly, our ability to distinguish the direction of the arrow of time can be quantified and shown to obey a universal law, which holds for both small and large systems. I will show how this law emerges from non-equilibrium fluctuation relations, and I will present experimental results that have verified its validity, using a driven quantum dot.
I will also discuss so-called "violations" of the second law. For isothermal processes, these violations occur when W < Delta F, where W is the work performed on the system and Delta F is the free energy change. A natural measure of the magnitude of the violation is given by the dimensionless quantity x = (Delta F - W)/kT. I will derive a simple expression that provides a bound on the probability of observing such violations, as a function of x, and I will argue that this expression provides the tightest possible universal bound. Quantum dots may provide experimental illustrations of the saturation of this bound.
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Date:06TuesdayMarch 2018Lecture
PNA-programmed Self Assemblies for Responsive Systems
More information Time 11:00 - 12:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Nicolas Winssinger
University of GenevaOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:06TuesdayMarch 2018Lecture
Students Seminar
More information Time 11:15 - 12:30Location Wolfson Building for Biological ResearchLecturer Prof. Yardena Samuels Organizer Department of Molecular Cell BiologyContact -
Date:06TuesdayMarch 2018Lecture
Harvesting the desert
More information Time 11:30 - 11:30Lecturer Prof. Aaron Kaplan
Dept. of Plant and Environmental Sciences, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem http://bio.huji.ac.il/staff_in.asp?staff_id=43Organizer Department of Plant and Environmental SciencesContact -
Date:06TuesdayMarch 2018Lecture
“Imaging the Future: How Neuroimaging Might Better People’s Lives”
More information Time 12:30 - 12:30Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. John Gabrieli
McGovern Institute for Brain Research at MITOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The lecture will be directly followed by an open meeting for...» The lecture will be directly followed by an open meeting for all members of the brain imaging community in Israel where we will discuss access to the 7-Tesla magnet that is at the heart of the national center. If you want to scan at 7T, please attend. -
Date:06TuesdayMarch 2018Lecture
“Dynamic recognition in protein-DNA complexes studied by simulations and experiments”
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Carlos Simmerling
Department of Chemistry, Stony Brook UniversityOrganizer Department of Chemical and Structural BiologyContact Abstract Show full text abstract about In contrast to proteins recognizing small-molecule ligands, ...» In contrast to proteins recognizing small-molecule ligands, DNA-dependent enzymes cannot rely solely on interactions in the substrate-binding centre to achieve their exquisite specificity. It is widely believed that substrate recognition by such enzymes involves a series of conformational changes in the enzyme-DNA complex with sequential gates favoring cognate DNA and rejecting nonsubstrates. However, direct evidence for such mechanism is limited to a few systems. We used molecular dynamics simulations to explore the dynamic recognition of oxidative DNA damage by glycosylase enzymes. The resulting energy profiles, supported by biochemical analysis of site-directed mutants disturbing the interactions along the proposed path, show that the glycosylases selectively facilitate recognition by stabilizing several intermediate states, helping the rapidly sliding enzyme avoid full extrusion of every encountered base for interrogation. Lesion recognition through multiple gating intermediates may be a common theme in DNA repair enzymes; we show that human and bacterial enzymes share a common recognition mechansim despite lack of sequence or structural similarity of their glycosylases.
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Date:07WednesdayMarch 2018Lecture
Developmental Club Series 2017-2018
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Orly Reiner Organizer Department of Molecular GeneticsContact -
Date:07WednesdayMarch 2018Lecture
Developmental Club Series 2017-2018
More information Time 10:00 - 10:00Title Human Brain Organoids on a Chip to Model Development and DiseaseLocation Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Orly Reiner Organizer Department of Molecular GeneticsContact -
Date:08ThursdayMarch 2018Lecture
“Tell Me What You See (not the Lennon-McCartney version)”
More information Time 09:00 - 10:00Location Max and Lillian Candiotty BuildingLecturer Dr. Jaim Prilusky
Bioinformatics UnitOrganizer Department of Life Sciences Core FacilitiesContact -
Date:08ThursdayMarch 2018Colloquia
Scaling Down the Laws of Thermodynamics
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Chris Jarzynski
University of MarylandOrganizer Faculty of PhysicsContact Abstract Show full text abstract about Thermodynamics provides a robust conceptual framework and se...» Thermodynamics provides a robust conceptual framework and set of laws that govern the exchange of energy and matter. Although these laws were originally articulated for macroscopic objects, nanoscale systems often exhibit “thermodynamic-like” behavior – biomolecular motors convert chemical fuel into mechanical work, and individual polymer molecules exhibit hysteresis and dissipation when stretched and contracted. To what extent can the laws of thermodynamics be “scaled down” to apply to individual microscopic systems, and what new features emerge at the nanoscale? I will review recent progress toward answering these questions.
The second law of thermodynamics is traditionally stated in terms of inequalities. For microscopic systems these inequalities can be replaced by stronger equalities, known as fluctuation relations, which relate equilib-rium properties to far-from-equilibrium fluctuations. The discovery and experimental validation of these rela-tions has stimulated interest in the feedback control of small systems, the closely related Maxwell demon par-adox, and the interpretation of the thermodynamic arrow of time. These developments have led to new tools for the analysis of non-equilibrium experiments and simulations, and they have refined our understanding of irreversibility and the second law.
I will also discuss challenges and open questions, including how to extend fluctuation relations to quantum systems, and how to formulate the first law of thermodynamics properly, when the interaction energy be-tween the system and its thermal surroundings cannot be neglected.
