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אוקטובר 05, 2015
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Date:24ראשוןנובמבר 2024הרצאה
Location matters - a spatial view of cellular interactions
More information שעה 09:00 - 10:00כותרת The Department of Molecular Cell Biology and the Department of Immunology & Regenerative Biology Guest Seminarמיקום בניין וולפסון למחקר ביולוגימרצה Dr. Michal Polonsky
California Institute of Technology (Caltech)מארגן המחלקה לביולוגיה מולקולרית של התאצרו קשר -
Date:24ראשוןנובמבר 2024הרצאה
2024 SPECIAL CLORE SEMINAR
More information שעה 13:15 - 14:30כותרת this year's nobel prizes explainedמיקום מרכז כנסים על-שם דויד לופאטימרצה Prof. Eran Hornstein, Prof. Eytan Domany, Prof. Sarel-Jacob Fleishman מארגן מרכז לפיזיקה ביולוגית עש קלורצרו קשר תקציר Show full text abstract about Physiology or Medicine Victor Ambros and Gary Ruvkun discov...» Physiology or Medicine
Victor Ambros and Gary Ruvkun discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation. Their groundbreaking discovery in the small worm C. elegans revealed a completely new principle of gene regulation. This turned out to be essential for multicellular organisms, including humans. MicroRNAs are proving to be fundamentally important for how organisms develop and function.
Physics
John Hopfield introduced a spin model that can store and reconstruct information. Geoffrey Hinton built on Hopfield’s idea to invent the Boltzmann Machine, that is able to learn from examples to reconstruct a set of desired patterns. He also popularized and improved Backpropagation of Errors, a method actually used in today’s advanced AI technology (e.g. Deep Learning).
Chemistry
The Nobel Prize in Chemistry 2024 is about proteins, life’s ingenious chemical tools. David Baker has succeeded with the almost impossible feat of building entirely new kinds of proteins. Demis Hassabis and John Jumper have developed an AI model to solve a 50-year-old problem: predicting proteins’ complex structures. These discoveries hold enormous potential.
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Date:28חמישינובמבר 2024סימפוזיונים
Physics - Colloquium
More information שעה 11:15 - 12:30כותרת Erasure detection with superconducting qubitsמיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Prof. Alex Retzker
Hebrew University of Jerusalemמארגן המחלקה לפיזיקה של מערכות מורכבותצרו קשר -
Date:28חמישינובמבר 2024הרצאה
Vision and AI
More information שעה 12:15 - 13:15כותרת Real-to-Sim: Towards interpretable and controllable digital twinsמיקום בניין יעקב זיסקינדמרצה Or Litany
Technionמארגן המחלקה למדעי המחשב ומתמטיקה שימושיתצרו קשר תקציר Show full text abstract about Do we live in a simulation? Perhaps we should consider the p...» Do we live in a simulation? Perhaps we should consider the possibility. Replicating real-world observations into a digital twin offers numerous potential benefits. For instance, in autonomous navigation, one could recreate safety-critical scenarios to test an agent's behavior more efficiently and without risking human lives. True-to-life simulations can enable counterfactual analysis, aiding in the interpretability of AI decision-making. Furthermore, they allow us to relive captured experiences for immersive entertainment.
In my research, I develop tools that enable these capabilities through the reconstruction of scene properties, such as geometry and color, and through perception methods like 3D scene segmentation and 3D object detection. This also includes the controllable generation and manipulation of content. To ensure scalability, my focus is particularly on representations that respect the symmetries in the data, such as rotation equivariance, and that can leverage large datasets at scale by minimizing the need for supervision.
Among these topics, in this talk, I will specifically highlight several of my recent papers. These include studies on 3D object detection from single images [1], neural fields for dynamic outdoor scene reconstruction [2], and piecewise equivariant representations [3].
[1] 3DiffTection: 3D Object Detection with Geometry-Aware Diffusion Features. Chenfeng Xu, Huan Ling, Sanja Fidler, Or Litany. CVPR 2024
[2] Zero-to-Hero: Enhancing Zero-Shot Novel View Synthesis via Attention Map Filtering, Ido Sobol, Chenfeng Xu, Or Litany. NeurIPS 2024
[3] EmerNeRF: Emergent Spatial-Temporal Scene Decomposition via Self-Supervision. Jiawei Yang, Boris Ivanovic, Or Litany, Xinshuo Weng, Seung Wook Kim, Boyi Li, Tong Che, Danfei Xu, Sanja Fidler, Marco Pavone, Yue Wang. ICLR 2024
Bio: Or Litany is a Senior Research Scientist at the NVIDIA Toronto AI research team, and an Assistant Professor at the Technion where he leads the LIT-Lab specializing in 3D computer vision and generative AI. He is an Azrieli Faculty Fellow and a Taub Fellow. Previously, he conducted postdoctoral research at Stanford University under the guidance of Prof. Leonidas Guibas, and at Meta AI Research (FAIR), where he was hosted by Prof. Jitendra Malik.
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Date:28חמישינובמבר 2024הרצאה
Cellular senescence: roles in regulation of pancreatic function and tumorigenesis
More information שעה 14:00 - 15:00מיקום בניין ע"ש מקס ולילאן קנדיוטימרצה Prof. Ittai Ben Porath
Dept of Developmental Biology and Cancer Research Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalemמארגן מרכז הבינתחומי לחקר סרטן עש מורוסצרו קשר -
Date:28חמישינובמבר 2024הרצאה
From Electrically-Powered Lab-On-a-Chip to Micro-Robot Platforms for Biomedical Applications
More information שעה 15:00 - 16:00מיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Prof. Gilad Yossifon
School of Mechanical Engineering, Dept. of Biomedical Engineering, University of Tel-Avivמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Micromotors/robots extend the reach of robotic operations to...» Micromotors/robots extend the reach of robotic operations to submillimeter dimensions and are becoming increasingly powerful for various tasks, such as the manipulation of micro/nanoscale cargo and single-cell analysis. These microrobots have the potential to significantly advance diagnostic testing and sample analysis, offering the benefits of traditional lab-on-a-chip devices (e.g., portability, efficiency) while overcoming current challenges (e.g., complexity, predetermined design, fluid control). Our recent findings have highlighted the unique advantage of using an electric field to enable unified, label-free, and selective micromotor-based cargo manipulation and transport [1]. Additionally, we have demonstrated the capability of electrically powered micromotors to (a) carry organelles or cells, (b) electro-deform cells as a novel means of biomechanical testing, and (c) electroporate cells for the transfection of drugs/genes [2]. Recently, the addition of magnetic field actuation has been shown to enable the operation of such hybrid-powered microrobots under near-physiological media conditions required for single-cell analysis [3]. Furthermore, optoelectronic control has been shown [4] to enable trajectory reconfiguration, directed self-assembly, and the parallelized operation of many such microrobots.
[1]Y. Wu, A. Fu & G. Yossifon, Small 1906682, 1-12 (2020).
[2]Y. Wu, A. Fu & G. Yossifon, PNAS 118, 38, e2106353118 (2021).
[3]Y. Wu, S. Yakov, A. Fu & G. Yossifon, Advanced Science 2204931 (2022).
[4]S. S. Das & G. Yossifon, Advanced Science 10, 2206183 (2023).
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Date:01ראשוןדצמבר 2024הרצאה
Fundamentals of Remote Sensing and Machine Learning for Earth Science
More information שעה 11:00 - 11:00מיקום בניין משפחת זוסמןמרצה Anna Brook
University of Haifaמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about Our Laboratory focuses on research that drives technological...» Our Laboratory focuses on research that drives technological,
environmental and social change. It includes advanced technologies
in the social aspect of environment management, embracing the
complexity of the human-environment relationship, and physical
model development for complex and non-trivial real-world problems in
the era of climate change. Our ultimate goal is to bridge the gap
between machine learning and geoscience for sustainability and
environmental management at the national and international (mainly
in the Mediterranean) scales. We understand that machine learning, in
general, and deep learning, in particular, offer promising tools to build
new data-driven models for Earth system components and thus build
our understanding of ecosystems. Yet, accepting that data-driven
machine learning approaches in geoscientific research cannot replace
physical modelling but strongly complement and enrich it. Our primary
scientific interests are developing hybrid approaches, coupling
physical processes (physical laws and physics-domain-specific
knowledge) with the versatility of data-driven machine learning, also
known as physics-aware machine learning, to better understand the
ecosystems, biodiversity, dynamic processes and environmental
responses to stressors, and emphasizing sustainability and decision
support system development aligned with the UN Sustainable
Development Goals (SDGs). -
Date:01ראשוןדצמבר 2024הרצאה
Memory in Capillary Networks
More information שעה 13:15 - 14:30כותרת The Clore Center for Biological Physics Seminarמיקום Physics Library
Libraryמרצה Dr. Bat-El Pinchasik תקציר Show full text abstract about Capillary networks are prevalent in nature and biology, play...» Capillary networks are prevalent in nature and biology, playing a crucial role in systems like animal vasculature and plant capillaries, with broad applications in medicine and science. However, many aspects of how these networks regulate and control flow remain unresolved. While the basic principles of capillary networks and their functions are well understood, ongoing research seeks to uncover how these systems dynamically respond to environmental changes, adapt to varying conditions, and whether they retain a memory of past states. Developing a model system for capillary networks allows us to pose exciting new questions, such as: "Can capillary networks store memory?"Building such a model presents two key challenges. First, the need to dynamically modify the nature of bonds within the networks and understand its impact on transport. Second, designing networks capable of evolving in response to external stimuli. Successfully addressing these challenges could transform our ability to actively control macroscale flow by manipulating local bonds within the networks.Here, a novel experimental model of capillary networks is proposed, consisting of hundreds of interconnected liquid diodes. Like electrical diodes, these microscale surface structures direct liquid flow in specific directions while preventing reverse flow. However, under certain conditions, liquid diodes may fail, permitting bidirectional flow and introducing bonds of varying properties within the capillary network.This system will allow us to investigate whether the wetting state of liquids in the network depends on its actuation history—essentially exploring whether capillary networks can exhibit memory. This question opens up new possibilities, including the potential to encode information within these networks, analyze how transport responds to external stimuli, study the interplay between global actuation and local fluid dynamics, explore the coupling between mechanics and flow, and better understand how information propagates through capillary systems. -
Date:02שנידצמבר 2024הרצאה
Midrasha on Groups Seminar
More information שעה 11:15 - 13:00כותרת Borel equivalence relation and hyperfinitnessמיקום גולדסמית-מתמטיקה
Room 108 - חדר 108מרצה Aranka Hrušková
Weizmann Instituteמארגן המחלקה למתמטיקהצרו קשר תקציר Show full text abstract about I will discuss Borel equivalence relation and hyperfinitness...» I will discuss Borel equivalence relation and hyperfinitness following [Kerr-Li] Section 4.8, [Loh1] Sections 3.1.1, 3.2.1, and [Fur1] Section 4.
For more details and the exact reference, click here. -
Date:02שנידצמבר 2024הרצאה
Midrasha on Groups Seminar
More information שעה 14:15 - 16:00כותרת Approximations of groups, cohomology and (semi-)stabilityמיקום בניין יעקב זיסקינד
Lecture Hall - Room 1 - אולם הרצאות חדר 1מרצה Benjamin Bachner
Weizmann Instituteמארגן המחלקה למתמטיקהצרו קשר תקציר Show full text abstract about Some of the most important open problems in group theory con...» Some of the most important open problems in group theory concern whether all groups can be metrically approximated by certain classes of groups. In particular, it is currently unknown whether there exist groups that are not (linear) sofic, hyperlinear, or MF.
We introduce the general problem of approximation of groups, as well as the related problem of stability, which asks whether almost homomorphisms from a group are close to actual homomorphisms. We recall a cohomological tool for stability introduced by De-Chiffre, Glebsky, Lubotzky, and Thom, which was used to prove the existence of groups that are not Frobenius-norm approximated. Moreover, we propose a weaker notion of semi-stability, which relates the different classes of approximated groups, and discuss how this cohomological tool can be adapted for this purpose.
For more details, check out our website.
We look forward to seeing you in one or both sessions next Monday. -
Date:02שנידצמבר 2024הרצאה
Special Guest Seminar
More information שעה 15:51 - 16:51מיקום בניין ע"ש מקס ולילאן קנדיוטי
Auditoriumמרצה Prof. Anat Herskovits -
Date:03שלישידצמבר 2024כנסים
TBA
More information שעה 08:00 - 08:00מיקום אולם הרצאות ע"ש גרהרד שמידטיושב ראש Shifra Lanskyמארגן המחלקה לביולוגיה מבנית וכימית -
Date:03שלישידצמבר 2024הרצאה
The Evolution of 7T (and Beyond) MRI in Basic Research and Clinical Practice
More information שעה 12:30 - 13:30מיקום אולם הרצאות ע"ש גרהרד שמידטמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about The Center for Magnetic Resonance Research (CMRR) has been a...» The Center for Magnetic Resonance Research (CMRR) has been at the forefront of magnetic resonance imaging (MRI) innovation, pioneering ultra-high field (7 Tesla and above) technologies that are revolutionizing brain research and clinical care. This presentation will explore CMRR's groundbreaking journey, from the first functional MRI study to development of high-resolution fMRI capabilities revealing cortical columns within the human cortex. The presentation will also explore the translation of these technologies into clinical practice, with a focus on the unique visualization capabilities of 7T MRI, particularly for enhancing the precision of Deep Brain Stimulation (DBS) procedures. By exploring the progression from the 7T system to the world’s first 10.5T human MRI, this presentation will illustrate how these transformative technologies have pushed the limits of imaging science, uncovering new insights into brain function and advancing personalized clinical care at the intersection of technology, research, and medicine.
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Date:03שלישידצמבר 2024הרצאה
TBA
More information שעה 14:00 - 15:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Natalie Elia
Dept. of Life Sciences Ben-Gurion Universityמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:04רביעידצמבר 2024כנסים
Milestones in Chemistry, Milestones in Life: A Symposium in Honour of Prof. Gershom (Jan M. L.) Martin
More information שעה 08:00 - 08:00מיקום מרכז כנסים על-שם דויד לופאטייושב ראש Mark Iron -
Date:04רביעידצמבר 2024הרצאה
students seminar series- Azrieli
More information שעה 10:30 - 12:30מיקום בניין קמיליה בוטנארצרו קשר -
Date:05חמישידצמבר 2024כנסים
Spatial Analysis of Development and Cancer
More information שעה 08:00 - 08:00יושב ראש Yosef Yardenמארגן המכון לחקר הטיפול בסרטן עש דואק -
Date:05חמישידצמבר 2024סימפוזיונים
Physics Colloquium
More information שעה 11:15 - 12:30כותרת IS EARTH EXCEPTIONAL?מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Prof. Livio Mario
Light refreshments at 11:00מארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהדף בית תקציר Show full text abstract about The questions “How did life on Earth begin?” and “Are we alo...» The questions “How did life on Earth begin?” and “Are we alone in the universe?” are arguably two of the most intriguing in science. While until recently these questions tended to be relegated to the “too difficult” box, the attempts to answer them have now become extraordinarily vibrant and dynamic frontiers of science. I will describe how the quest for cosmic life follows two parallel, independent lines of research: cutting-edge laboratory studies aimed at determining whether life can emerge from pure chemistry, and advanced astronomical observations searching for signs of life on other planets and moons in the solar system and around stars other than the Sun. I will examine how using knowledge acquired through ingenious chemical experimentation, geological studies, advanced astronomical observations, and imaginative theorizing researchers have managed to delineate a plausible pathway leading from the formation of the Earth to the appearance of the early biological cells. -
Date:05חמישידצמבר 2024הרצאה
Vision and AI
More information שעה 12:15 - 13:15כותרת Semantic Vector Representations in the Service of Computer Visionמיקום בניין יעקב זיסקינדמרצה Or Hirschorn
TAUמארגן המחלקה למדעי המחשב ומתמטיקה שימושיתצרו קשר תקציר Show full text abstract about In this talk, we examine the benefits of semantic vector rep...» In this talk, we examine the benefits of semantic vector representations for computer vision, highlighting their advantages over pixel-space representations in various applications. We first consider the problem of human motion anomaly detection and demonstrate the advantage of doing that over human poses. Then, we introduce a novel category-agnostic approach, termed GraphCape, that enables pose estimation across any category. Finally, we will explore further improvements for structure-based CAPE networks, dynamically predicting useful connections.
Bio: Or Hirschorn is a PhD candidate at Tel Aviv University, advised by Prof. Shai Avidan. His research interests are in developing methods for learning semantic vector representations of images and their applications for a variety of vision tasks. His MSc work won him the Weinstein scholarship for outstanding signal processing research.
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Date:05חמישידצמבר 2024הרצאה
Neuroprotective and Anticonvulsant Effects of Cannabinoids with Neurotrauma
More information שעה 12:30 - 13:30מיקום Benoziyo Brain Research Building
113מרצה Prof.Linda Friedman מארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Traumatic brain (TBI) injuries result in profound local hypo...» Traumatic brain (TBI) injuries result in profound local hypoperfusion, ischemia, chronic inflammation and refractory seizures(post-traumatic epilepsy (PTE)), and restrict drug delivery to the site of impact so that peripheral treatment alone would have limited access to the site of injury during the most critical phases of neurotrauma. Cannabidiol (CBD), the major non-psychotropic cannabinoid, has anti-convulsant, anti-inflammatory, anti-nociceptive, antioxidant, and immuno-suppressive properties not fully understood. In pre-juvenile rats, microinjection of CBD attenuated kainate(KA)-induced seizures to a greater extent than intraperitoneal injection, indicating that local drug administration was more effective. In adult rats after experimental TBI, our modified CBD-infused implant applied extradural with oil injection supplementation restored vestibulomotorand cognitive functions compared to systemic treatment alone. We questioned whether the CBD or the low concentrations of THC in the extract was responsible for behavioral and cellular recovery.We hypothesized that an optimal ratio of cannabidiol (CBD) to tetrahydrocannabinol (THC) is required to protect against neuropathological consequences following TBI greater than either substance alone. Varied CBD:THC extract concentrations were compared with hempCBD lacking THC (CBD0). Neurons, glia, and parvalbumin interneurons (PV-INs) were evaluated. Weight loss was observed following high doses of THC dominant cannabis, THC100:1. Neuroscoresand vestibulomotorperformance were restored more with CBD:THC300:1-10:1. However, THC dominant treatments resulted in early onset to spontaneous seizures post-TBI. In a non-reward T-maze, the CBD10:1group had the highest alternation rates; TBI + vehicle, CBD0, CBD1:1, and THC100:1treatment groups had the lowest. The novel object recognition memory task showed CBD300:1treated animals had the best performance, while TBI or THC100:1treated groups had the worst. The forced swim test (FST) showed immobility time was highest after TBI and lowest after THC100:1treatment. The elevated plus maze (EPM) revealed the CBD0group spent the most time in closed arms. Both tests indicate that reduced anxiety was THC dependent. All combinations resulted in reduced injury but CBD10:1and THC20:1gave the most protection and THC100:1the least. Reduced anxiety level was THC dependent but higher doses were pro-convulsant cautioning THC dosing. Reduced GFAP labeling was highest with CBD dominant cannabis supporting its neuroprotective role against inflammation. Rescue of diminished bilateral PV-INs was observed within the hippocampus and medial prefrontal cortex (mPFC) with CBD dominant treatment (CBD300, CBD0) supporting their anticonvulsant effect. Loss of PV-INs with THC dominant treatment supports their proconvulsant effect. Thus, CBD and THC have different beneficial therapeutic effects indicating an optimal concentration ratio is critical for optimal neuropathological therapeutics.Light refreshments before the seminar