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January 01, 2013

  • Date:16SundayJune 2024

    Plan A+ - How geoengineering using stratospheric aerosols could play a role in climate policy

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    Time
    13:00 - 14:00
    Location
    https://weizmann.zoom.us/j/98884644964?pwd=SUF0cnVEZndYWmw1azFPQlhrTStuQT09
    LecturerDr. Peter Irvine
    Assistant Professor, University College London, Earth Sciences
    Organizer
    Sustainability and Energy Research Initiative (SAERI)
    Contact
    Lecture
  • Date:17MondayJune 2024

    Midrasha on Groups Seminar

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    Time
    11:15 - 13:00
    Title
    Density of growth-rates of subgroups of a free group
    Location
    Jacob Ziskind Building
    LecturerGal Yehuda
    Yale
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about We prove the set of growth-rates of subgroups of a rank~r fr...»
    We prove the set of growth-rates of subgroups of a rank~r free group is dense in [1,2r−1]. Our main technical contribution is a concentration result for the leading eigenvalue of the non-backtracking matrix in the configuration model.

     

    Based on a joint work with Michali Louvaris and Dani Wise.
    Lecture
  • Date:17MondayJune 2024

    Foundations of Computer Science Seminar

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    Time
    11:15 - 12:15
    Title
    Coding Theory in Almost-Linear Time and Sub-Linear Space
    Location
    Jacob Ziskind Building
    LecturerDana Moshkovitz
    UT Austin
    Organizer
    Department of Computer Science and Applied Mathematics
    Contact
    AbstractShow full text abstract about Typical time-efficient encoding and decoding algorithms for ...»
    Typical time-efficient encoding and decoding algorithms for error correcting codes use linear space. We construct asymptotically good codes that can be deterministically encoded in almost linear time and sub-linear space, as well as asymptotically good codes that can be deterministically decoded in this complexity. The encodable codes are based on condenser graphs. The decodable codes are based on locally correctable codes and a new efficient derandomization method. We believe that the new derandomization method is of independent interest.

    The talk is based on joint works with Joshua Cook (University of Texas at Austin).
    Lecture
  • Date:17MondayJune 2024

    Employing Phage Display Technology for Developing Potential Human Therapeutic Antibodies

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    Time
    14:00 - 15:00
    Location
    Max and Lillian Candiotty Building
    LecturerProf. Ahuva Nissim
    WHRI, Queen Mary University of London
    Organizer
    Department of Life Sciences Core Facilities
    Contact
    Lecture
  • Date:17MondayJune 2024

    Midrasha on Groups Seminar

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    Time
    14:15 - 16:00
    Title
    Cosystolic expanders
    Location
    Jacob Ziskind Building
    LecturerShai Evra
    HUJI
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about In this talk we will introduce a notion slightly weaker than...»
    In this talk we will introduce a notion slightly weaker than the coboundary expansion notion of Linial–Meshulam called the cosystolic expansion,  which is strong enough to implies Gromov’s topological property for high dimensional complexes. We will then give a criterion for proving this notion assuming our complex has good enough local structure. Examples of complexes with such good local structure are quotient of affine buildings (e.g. the LSV complexes). This allow us to present a family of bounded degree complexes with the topological overlapping property.

    This is based in a joint work with Tali Kaufman.
    Lecture
  • Date:18TuesdayJune 2024

    From the lab to the clinic: A toolbox for single-molecule epigenetic analysis of DNA

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Yuval Ebenstein
    Department of Physical Chemistry Tel-Aviv University
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Short-read DNA sequencing (NGS) is revolutionizing all field...»
    Short-read DNA sequencing (NGS) is revolutionizing all fields of biological research. Still, it fails to extract the full range of information associated with genetic material and cannot resolve many variations between genomes. The information content of the genome extends beyond the base sequence in the form of chemical modifications such as DNA methylation, damage lesions, or chromosomal association with DNA-binding proteins (chromatin). For the last decade, our lab has been developing tools for genomic analysis at the single-cell and single-molecule levels. I’ll present a biochemical and physical toolbox for mapping epigenetic modifications in the genome and demonstrate its application in clinical cancer research.
    Lecture
  • Date:19WednesdayJune 2024

    Machine Learning and Statistics Seminar

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    Time
    11:15 - 12:15
    Title
    Making SGD as Parameter-Free as Possible
    Location
    Jacob Ziskind Building
    LecturerYair Carmon
    TAU
    Organizer
    Department of Computer Science and Applied Mathematics
    Contact
    AbstractShow full text abstract about While stochastic optimization methods drive continual improv...»
    While stochastic optimization methods drive continual improvements in machine learning, choosing the optimization parameters—particularly the learning rate (LR)—remains challenging. In this talk, I will describe our work on eliminating LR tuning from stochastic gradient descent (SGD) under convexity assumptions. Our starting point is a novel post-hoc empirical certificate for the SGD step size choice, which yields strong parameter-free guarantees via a bisection procedure. This certificate also inspires a tuning-free dynamic SGD step size formula, which we call Distance over Gradients (DoG). For smooth stochastic objectives, we combine DoG with UniXGrad (Kavis et al., 2019) to obtain the first accelerated parameter-free method. Finally, we develop a “price of adaptivity” framework that allows us to evaluate the inherent cost of not knowing problem parameters in advance. In several settings, our lower bounds nearly match existing upper bounds, establishing there is no parameter-free lunch. 

    Joint work with Maor Ivgi, Itai Kreisler, and Oliver Hinder.
    Lecture
  • Date:19WednesdayJune 2024

    LS Luncheon

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    Time
    12:00 - 14:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Yifat Merbl
    Department of Systems Immunology
    Contact
    Lecture
  • Date:20ThursdayJune 2024

    Physics colloquium

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    Time
    11:15 - 12:30
    Title
    Stochastic resonance in polymer solution channel flow
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerProf. Victor Steinberg
    Weizmann Institute of Science
    Organizer
    Department of Physics of Complex Systems
    Contact
    AbstractShow full text abstract about A cooperative resonance effect in a stochastic nonlinear dyn...»
    A cooperative resonance effect in a stochastic nonlinear dynamical system subjected to external weak periodic forcing, called stochastic resonance (SR), has been extensively studied for the past forty years. Here I discuss the experimentally unexpected observation of SR above an elastic non-modal instability of an inertia-less channel flow of polymer solution (much more complicated than stochastic dynamical flow) due to finite-size white noise perturbations. This flow is shown to be linearly stable similar to Newtonian parallel shear flow. First, I briefly describe viscoelastic flow with curved streamlines, where linear elastic normal mode instability at the critical Weissenberg number, Wic, has been observed and characterized, and the elastic instability mechanism has been explained and experimentally validated. Furthermore, at Wi>>Wic, “elastic turbulence” (ET), a chaotic flow arising via secondary instability, is experimentally discovered, characterized and theoretically explained, while elastic instability in straight channel flow is found from the direct transition from laminar to chaotic flow in the transition flow regime is found. At the secondary instability, ET is observed, and further on the next transition to the unexpected drag reduction flow regime takes place, accompanied by elastic waves previously discovered and characterized earlier. Moreover, we propose and experimentally validate a mechanism of amplification of the wall normal fluctuating vortices by the elastic waves. The elastic waves play the key role in the energy transfer from the main flow to the wall-normal fluctuating vortices. Finally, we report on recently discovered SRs only in a limited subrange of weak elastic waves just above Wic, their characterization, and their role in the transition to a chaotic flow.
    Colloquia
  • Date:20ThursdayJune 2024

    Spotlight on Science

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    Time
    13:00 - 14:00
    Title
    TBA
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Organizer
    Science for All Unit
    Contact
    Lecture
  • Date:20ThursdayJune 2024

    Geometric Functional Analysis and Probability Seminar

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    Time
    13:30 - 14:30
    Title
    Expander with respect to random regular graphs
    Location
    Jacob Ziskind Building
    LecturerManor Mendel
    OpenU
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about Expander is a family of constant degree graphs with spectral...»
    Expander is a family of constant degree graphs with spectral gaps larger than some positive constant. From a Metric Geometry perspective, the spectral gap implies their non-embeddability in Hilbert space in any meaningful way. It is therefore customary in Metric Geometry to generalize them to expanders that do not embed well in a given metric space X, called X-expanders. Non-Hilbertian Expanders were first studied by Linial-London-Rabinovich, Matousek, and Gromov. In a breakthrough result, V. Lafforgue proved the existence of a super(-reflexive)-expander. It is an open question whether every (classical) expander is also a super-expander.

    In this talk I will discuss the existence of expanders with respect to random regular graphs. It gives the first example of a metric space X for which some expanders are X-expanders and some are not X-expanders. The construction is based on the zigzag expanders of Reingold-Vadhan-Wigderson and uses concepts and techniques from expander graph theory, random graph theory, probability, local theory of Banach spaces, and Alexandrov spaces.

    The talk is based on joint papers with A. Naor and a forthcoming joint paper with A. Eskenazis and A. Naor.
    Lecture
  • Date:20ThursdayJune 2024

    Glioma cellular heterogeneity in time and space

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    Time
    14:00 - 15:00
    Location
    Max and Lillian Candiotty Building
    LecturerProf. Itay Tirosh
    The Dr. Celia Zwillenberg-Fridman and Dr. Lutz Zwillenberg Career Development Chair Department of Molecular Cell Biology Faculty of Biology
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:23SundayJune 2024

    The Clore Center for Biological Physics

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    Time
    12:45 - 14:30
    Title
    The role of sign indefinite invariants in shaping turbulent cascades.
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerMichal Shavit, Postdoctoral fellow
    Courant NYU
    Organizer
    Clore Center for Biological Physics
    Contact
    AbstractShow full text abstract about Our work answers a nearly 60-year quest to derive the turbul...»
    Our work answers a nearly 60-year quest to derive the turbulent spectrum of weakly interacting internal gravity waves from first principles. The classical wave-turbulence approach didn’t work, as the underlying equation, both in 2D and 3D, is an anisotropic, non-canonical Hamiltonian equation.
    A key consequence of the non-canonical Hamiltonian is the conservation of a sign-indefinite quadratic invariant alongside the sign-definite quadratic energy. In 2D, this allows us to derive a much simpler kinetic equation. We leverage this simplification into the derivation of solutions of the kinetic equation, one of which is the turbulent spectrum of weakly interacting 2D internal gravity waves. Our spectrum exactly matches the phenomenological oceanic Garrett-Munk spectrum in the limit of large vertical wave numbers and zero rotation.
    This talk is based on recent joint works with Oliver Bühler and Jalal Shatah
    arXiv:2311.04183 (to appear soon in PRL).
    arXiv:2406.06010.
    FOR THE LATEST UPDATES AND CONTENT ON SOFT MATTER AND BIOLOGICAL PHYSICS AT THE WEIZMANN, VISIT OUR WEBSITE: https://www.biosoftweizmann.com/
    Lecture
  • Date:23SundayJune 2024

    Pre-SAAC Symposium on Developmental Biology and Regenerative Medicine

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    Time
    14:00 - 16:30
    Location
    The David Lopatie Conference Centre
    Contact
    Lecture
  • Date:23SundayJune 2024

    Memory and Obliviscence:From Random to Structured Material 

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    Time
    14:15 - 15:30
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerAntonis Georgiou-Student Seminar-PhD Thesis Defense
    Advisor: Prof. Misha Tsodyks Dept of Brain Sciences, WIS
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about The study of human memory is a rich field with a history tha...»
    The study of human memory is a rich field with a history that spans over a century, traditionally investigated through the prism of psychology. Drawing inspiration from this vast pool of findings, we approached the subject with a more physics-oriented mindset based on first principles. For this reason, we combined mathematical modelling of established ideas from the literature of psychology with large-scale experimentation. In particular, we created a model based on the concept of retroactive interference that states that newly encoded items hinder the retention of older ones in memory. We show that this simple mechanism is sufficient to describe a variety of experimental data of recognition memory with different categories of verbal and pictorial stimuli. The model has a single free parameter and can be solved analytically. We then focus on recall and recognition memory of stories. This transition from discrete random lists to coherent continuous stimuli such as stories introduces a new challenge when it comes to the quantification and the analysis of the results. To address this, we have developed a pipeline that employs large language models and showed that it performs comparably to human evaluators. Using this tool we were able to show that recall scales linearly with recognition and story size for the range we examined. Finally, we discovered that when stories are presented in a scrambled manner, even though recall performance drops, subjects seem to reconstruct the material in their recall in alignment to the unscrambled version.
    Lecture
  • Date:24MondayJune 2024

    Foundations of Computer Science Seminar

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    Time
    11:15 - 12:15
    Title
    Differentially Private Space-Efficient Algorithms for Frequency Moment Estimation in the Turnstile Model
    Location
    Jacob Ziskind Building
    LecturerRachel Cummings
    Columbia University
    Organizer
    Department of Computer Science and Applied Mathematics
    Contact
    AbstractShow full text abstract about The  turnstile continual release model of differential priva...»
    The  turnstile continual release model of differential privacy captures scenarios where a privacy-preserving real-time analysis  is sought for a dataset evolving  through additions and deletions.  In typical applications of real-time data analysis, both the length of the stream T and the size of the universe |U| from which data come can be extremely large. This motivates the study of private algorithms in the turnstile setting using space sublinear in both T and |U|. In this paper, we give the first sublinear space differentially private algorithms for the fundamental problems of counting distinct elements and $ell_p$-frequency moment estimation in the turnstile streaming model. For counting distinct elements, our algorithm achieves O(T^{1/3}) space and additive error, and a (1 eta)-relative approximation for all eta in (0,1). Our result significantly improves upon the space requirements of the state-of-the-art for this problem in this model, which has a linear dependency in both T and |U|, while still achieving an additive error that is close to the known Omega(T^{1/4}) lower bound for arbitrary streams. This addresses an open question posed in prior work about designing low-memory mechanisms for this problem. For the more general problem of L_p-frequency moment estimation, our algorithm achieves an additive error and space of O(T^{1/3}), and a (1 eta)-relative approximation for all eta in (0,1). We also give a space lower bound for this problem, which shows that any algorithm that uses our techniques must use space Omega}(T^{1/3}). Joint work with Alessandro Epasto, Jieming Mao, Tamalika Mukherjee, Tingting Ou, and Peilin Zhong.
    Lecture
  • Date:24MondayJune 2024

    Midrasha on Groups Seminar

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    Time
    11:15 - 13:00
    Title
    Spectral gap absorption principle for simple groups
    Location
    Jacob Ziskind Building
    LecturerYuval Grofine
    Weizmann
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about The aim of the talk is to show that simple groups over local...»
    The aim of the talk is to show that simple groups over local fields have a spectral gap absorption principle. That is, that if a representation that doesn't have almost invariant vectors is tensored with another representation, then the tensored representation still doesn't have almost invariant vectors. This property was conjectured by Uri Bader and Roman Sauer in their paper about unitary cohomology, and was proved there in some of the cases. We prove the general result. Such tensor products appear naturally when one works with restriction and induction of representations, and it is useful to know that the spectral gap is preserved.

     

    I will (try to) give a survey of the rich and beautiful theory of representations of semisimple groups, and show how to use the celebrated Langlands classification theorem, as well as some more modern results, in order to prove the theorem.
    Lecture
  • Date:24MondayJune 2024

    Midrasha on Groups Seminar

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    Time
    14:15 - 16:00
    Title
    Good locally testable codes
    Location
    Jacob Ziskind Building
    LecturerAlex Lubotzky
    Weizmann
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about An error-correcting code is locally testable (LTC) if there ...»
    An error-correcting code is locally testable (LTC) if there is a random tester that reads only a small number of bits of a given word and decides whether the word is in the code, or at least close to it. A long-standing problem asks if there exists such a code that also satisfies the golden standards of coding theory: constant rate and constant distance. Unlike the classical situation in coding theory, random codes are not LTC, so this problem is a challenge of a new kind. 

     

    We construct such codes based on what we call (Ramanujan) Left/Right Cayley square complexes.  These objects seem to be of independent group-theoretic interest. The codes built on them are 2-dimensional versions of the expander codes constructed by Sipser and Spielman (1996). 

     

    The main result and lecture will be self-contained. But we hope also to explain how the seminal work of Howard Garland (1972) on the cohomology of quotients of the Bruhat–Tits buildings of p-adic Lie group has led to this construction (even though it is not used at the end). 

     

    Based on joint work with I. Dinur, S. Evra, R. Livne, and S. Mozes.
    Lecture
  • Date:25TuesdayJune 2024

    Mechano-regulation of gene expression in striated muscle

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    Time
    10:00 - 11:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerDr. Daria Amiad-Pavlov
    Perelman School of Medicine, University of Pennsylvania
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about In recent years the cell nucleus emerged as a dynamic mechan...»
    In recent years the cell nucleus emerged as a dynamic mechanosensor capable of sensing and transducing mechanical signals into cellular responses to facilitate homeostasis and adaptation to changing environmental conditions. The constantly beating heart has a remarkable ability to adapt its structure and contractility in response to changes in mechanical load. I am introducing unique, live, and dynamic imaging approaches to investigate how nuclei in the mature heart can provide such mechano-protection and mechano-regulation of the genome. I will present a novel assay to couple cytoskeletal to nuclear strain transfer in the beating cardiomyocyte, and its further application to decipher mechanisms of nuclear damage in dilated cardiomyopathy caused by mutations in the LMNA gene (LMNA-DCM). This work pinpoints localized microtubule-dependent forces, but surprisingly not actomyosin contractility, as drivers of nuclear damage in LMNA-DCM, highlighting new therapeutic avenues. I will further discuss the role of mechanical signaling in spatial organization of the genome within the nucleus, to regulate transcriptionally active and repressed hubs, and downstream gene expression.
    Lecture
  • Date:25TuesdayJune 2024

    Molecular Manipulation of Heterogeneous Electrocatalysis Using Metal-Organic Frameworks

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    Time
    11:00 - 12:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Idan Hod
    Department of Chemistry at Ben-Gurion University of the Negev, BGU
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    AbstractShow full text abstract about Electrocatalytically driven reactions that produce alternati...»
    Electrocatalytically driven reactions that produce alternative fuels and chemicals are considered as a useful means to store renewable
    energy in the form of chemical bonds. in recent years there has been a significant increase in research efforts aiming to develop highly
    efficient electrocatalysts that are able to drive those reactions. Yet, despite having made significant progress in this field, there is still a
    need for developing new materials that could function both as active and selective electrocatalysts.
    In that respect, Metal–Organic Frameworks (MOFs), are an emerging class of hybrid materials with immense potential in electrochemical
    catalysis. Yet, to reach a further leap in our understanding of electrocatalytic MOF-based systems, one also needs to consider the welldefined
    structure and chemical modularity of MOFs as another important virtue for efficient electrocatalysis, as it can be used to fine-tune
    the immediate chemical environment of the active site, and thus affect its overall catalytic performance. Our group utilizes Metal-Organic
    Frameworks (MOFs) based materials as a platform for imposing molecular approaches to control and manipulate heterogenous
    electrocatalytic systems. In this talk, I will present our recent study on electrocatalytic schemes involving MOFs, acting as: a) electroactive
    unit that incorporates molecular electrocatalysts, or b) non-electroactive MOF-based membranes coated on solid heterogenous catalysts.
    Lecture

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