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January 01, 2013
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Date:16SundayJune 2024Lecture
Plan A+ - How geoengineering using stratospheric aerosols could play a role in climate policy
More information Time 13:00 - 14:00Location https://weizmann.zoom.us/j/98884644964?pwd=SUF0cnVEZndYWmw1azFPQlhrTStuQT09Lecturer Dr. Peter Irvine
Assistant Professor, University College London, Earth SciencesOrganizer Sustainability and Energy Research Initiative (SAERI)Contact -
Date:17MondayJune 2024Lecture
Midrasha on Groups Seminar
More information Time 11:15 - 13:00Title Density of growth-rates of subgroups of a free groupLocation Jacob Ziskind BuildingLecturer Gal Yehuda
YaleOrganizer Department of MathematicsContact Abstract Show full text abstract about We prove the set of growth-rates of subgroups of a rank~r fr...» We prove the set of growth-rates of subgroups of a rank~r free group is dense in [1,2r−1]. Our main technical contribution is a concentration result for the leading eigenvalue of the non-backtracking matrix in the configuration model.
Based on a joint work with Michali Louvaris and Dani Wise.
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Date:17MondayJune 2024Lecture
Foundations of Computer Science Seminar
More information Time 11:15 - 12:15Title Coding Theory in Almost-Linear Time and Sub-Linear SpaceLocation Jacob Ziskind BuildingLecturer Dana Moshkovitz
UT AustinOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about Typical time-efficient encoding and decoding algorithms for ...» Typical time-efficient encoding and decoding algorithms for error correcting codes use linear space. We construct asymptotically good codes that can be deterministically encoded in almost linear time and sub-linear space, as well as asymptotically good codes that can be deterministically decoded in this complexity. The encodable codes are based on condenser graphs. The decodable codes are based on locally correctable codes and a new efficient derandomization method. We believe that the new derandomization method is of independent interest.
The talk is based on joint works with Joshua Cook (University of Texas at Austin).
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Date:17MondayJune 2024Lecture
Employing Phage Display Technology for Developing Potential Human Therapeutic Antibodies
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Ahuva Nissim
WHRI, Queen Mary University of LondonOrganizer Department of Life Sciences Core FacilitiesContact -
Date:17MondayJune 2024Lecture
Midrasha on Groups Seminar
More information Time 14:15 - 16:00Title Cosystolic expandersLocation Jacob Ziskind BuildingLecturer Shai Evra
HUJIOrganizer Department of MathematicsContact Abstract Show full text abstract about In this talk we will introduce a notion slightly weaker than...» In this talk we will introduce a notion slightly weaker than the coboundary expansion notion of Linial–Meshulam called the cosystolic expansion, which is strong enough to implies Gromov’s topological property for high dimensional complexes. We will then give a criterion for proving this notion assuming our complex has good enough local structure. Examples of complexes with such good local structure are quotient of affine buildings (e.g. the LSV complexes). This allow us to present a family of bounded degree complexes with the topological overlapping property.
This is based in a joint work with Tali Kaufman.
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Date:18TuesdayJune 2024Lecture
From the lab to the clinic: A toolbox for single-molecule epigenetic analysis of DNA
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Yuval Ebenstein
Department of Physical Chemistry Tel-Aviv UniversityOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Short-read DNA sequencing (NGS) is revolutionizing all field...» Short-read DNA sequencing (NGS) is revolutionizing all fields of biological research. Still, it fails to extract the full range of information associated with genetic material and cannot resolve many variations between genomes. The information content of the genome extends beyond the base sequence in the form of chemical modifications such as DNA methylation, damage lesions, or chromosomal association with DNA-binding proteins (chromatin). For the last decade, our lab has been developing tools for genomic analysis at the single-cell and single-molecule levels. I’ll present a biochemical and physical toolbox for mapping epigenetic modifications in the genome and demonstrate its application in clinical cancer research. -
Date:19WednesdayJune 2024Lecture
Machine Learning and Statistics Seminar
More information Time 11:15 - 12:15Title Making SGD as Parameter-Free as PossibleLocation Jacob Ziskind BuildingLecturer Yair Carmon
TAUOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about While stochastic optimization methods drive continual improv...» While stochastic optimization methods drive continual improvements in machine learning, choosing the optimization parameters—particularly the learning rate (LR)—remains challenging. In this talk, I will describe our work on eliminating LR tuning from stochastic gradient descent (SGD) under convexity assumptions. Our starting point is a novel post-hoc empirical certificate for the SGD step size choice, which yields strong parameter-free guarantees via a bisection procedure. This certificate also inspires a tuning-free dynamic SGD step size formula, which we call Distance over Gradients (DoG). For smooth stochastic objectives, we combine DoG with UniXGrad (Kavis et al., 2019) to obtain the first accelerated parameter-free method. Finally, we develop a “price of adaptivity” framework that allows us to evaluate the inherent cost of not knowing problem parameters in advance. In several settings, our lower bounds nearly match existing upper bounds, establishing there is no parameter-free lunch.
Joint work with Maor Ivgi, Itai Kreisler, and Oliver Hinder.
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Date:19WednesdayJune 2024Lecture
LS Luncheon
More information Time 12:00 - 14:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Yifat Merbl
Department of Systems ImmunologyContact -
Date:20ThursdayJune 2024Colloquia
Physics colloquium
More information Time 11:15 - 12:30Title Stochastic resonance in polymer solution channel flowLocation Edna and K.B. Weissman Building of Physical SciencesLecturer Prof. Victor Steinberg
Weizmann Institute of ScienceOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about A cooperative resonance effect in a stochastic nonlinear dyn...» A cooperative resonance effect in a stochastic nonlinear dynamical system subjected to external weak periodic forcing, called stochastic resonance (SR), has been extensively studied for the past forty years. Here I discuss the experimentally unexpected observation of SR above an elastic non-modal instability of an inertia-less channel flow of polymer solution (much more complicated than stochastic dynamical flow) due to finite-size white noise perturbations. This flow is shown to be linearly stable similar to Newtonian parallel shear flow. First, I briefly describe viscoelastic flow with curved streamlines, where linear elastic normal mode instability at the critical Weissenberg number, Wic, has been observed and characterized, and the elastic instability mechanism has been explained and experimentally validated. Furthermore, at Wi>>Wic, “elastic turbulence” (ET), a chaotic flow arising via secondary instability, is experimentally discovered, characterized and theoretically explained, while elastic instability in straight channel flow is found from the direct transition from laminar to chaotic flow in the transition flow regime is found. At the secondary instability, ET is observed, and further on the next transition to the unexpected drag reduction flow regime takes place, accompanied by elastic waves previously discovered and characterized earlier. Moreover, we propose and experimentally validate a mechanism of amplification of the wall normal fluctuating vortices by the elastic waves. The elastic waves play the key role in the energy transfer from the main flow to the wall-normal fluctuating vortices. Finally, we report on recently discovered SRs only in a limited subrange of weak elastic waves just above Wic, their characterization, and their role in the transition to a chaotic flow. -
Date:20ThursdayJune 2024Lecture
Spotlight on Science
More information Time 13:00 - 14:00Title TBALocation Gerhard M.J. Schmidt Lecture HallOrganizer Science for All UnitContact -
Date:20ThursdayJune 2024Lecture
Geometric Functional Analysis and Probability Seminar
More information Time 13:30 - 14:30Title Expander with respect to random regular graphsLocation Jacob Ziskind BuildingLecturer Manor Mendel
OpenUOrganizer Department of MathematicsContact Abstract Show full text abstract about Expander is a family of constant degree graphs with spectral...» Expander is a family of constant degree graphs with spectral gaps larger than some positive constant. From a Metric Geometry perspective, the spectral gap implies their non-embeddability in Hilbert space in any meaningful way. It is therefore customary in Metric Geometry to generalize them to expanders that do not embed well in a given metric space X, called X-expanders. Non-Hilbertian Expanders were first studied by Linial-London-Rabinovich, Matousek, and Gromov. In a breakthrough result, V. Lafforgue proved the existence of a super(-reflexive)-expander. It is an open question whether every (classical) expander is also a super-expander.
In this talk I will discuss the existence of expanders with respect to random regular graphs. It gives the first example of a metric space X for which some expanders are X-expanders and some are not X-expanders. The construction is based on the zigzag expanders of Reingold-Vadhan-Wigderson and uses concepts and techniques from expander graph theory, random graph theory, probability, local theory of Banach spaces, and Alexandrov spaces.
The talk is based on joint papers with A. Naor and a forthcoming joint paper with A. Eskenazis and A. Naor.
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Date:20ThursdayJune 2024Lecture
Glioma cellular heterogeneity in time and space
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Itay Tirosh
The Dr. Celia Zwillenberg-Fridman and Dr. Lutz Zwillenberg Career Development Chair Department of Molecular Cell Biology Faculty of BiologyOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:23SundayJune 2024Lecture
The Clore Center for Biological Physics
More information Time 12:45 - 14:30Title The role of sign indefinite invariants in shaping turbulent cascades.Location Gerhard M.J. Schmidt Lecture HallLecturer Michal Shavit, Postdoctoral fellow
Courant NYUOrganizer Clore Center for Biological PhysicsContact Abstract Show full text abstract about Our work answers a nearly 60-year quest to derive the turbul...» Our work answers a nearly 60-year quest to derive the turbulent spectrum of weakly interacting internal gravity waves from first principles. The classical wave-turbulence approach didn’t work, as the underlying equation, both in 2D and 3D, is an anisotropic, non-canonical Hamiltonian equation.
A key consequence of the non-canonical Hamiltonian is the conservation of a sign-indefinite quadratic invariant alongside the sign-definite quadratic energy. In 2D, this allows us to derive a much simpler kinetic equation. We leverage this simplification into the derivation of solutions of the kinetic equation, one of which is the turbulent spectrum of weakly interacting 2D internal gravity waves. Our spectrum exactly matches the phenomenological oceanic Garrett-Munk spectrum in the limit of large vertical wave numbers and zero rotation.
This talk is based on recent joint works with Oliver Bühler and Jalal Shatah
arXiv:2311.04183 (to appear soon in PRL).
arXiv:2406.06010.
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Date:23SundayJune 2024Lecture
Pre-SAAC Symposium on Developmental Biology and Regenerative Medicine
More information Time 14:00 - 16:30Location The David Lopatie Conference CentreContact -
Date:23SundayJune 2024Lecture
Memory and Obliviscence:From Random to Structured Material
More information Time 14:15 - 15:30Location Nella and Leon Benoziyo Building for Brain ResearchLecturer Antonis Georgiou-Student Seminar-PhD Thesis Defense
Advisor: Prof. Misha Tsodyks Dept of Brain Sciences, WISOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The study of human memory is a rich field with a history tha...» The study of human memory is a rich field with a history that spans over a century, traditionally investigated through the prism of psychology. Drawing inspiration from this vast pool of findings, we approached the subject with a more physics-oriented mindset based on first principles. For this reason, we combined mathematical modelling of established ideas from the literature of psychology with large-scale experimentation. In particular, we created a model based on the concept of retroactive interference that states that newly encoded items hinder the retention of older ones in memory. We show that this simple mechanism is sufficient to describe a variety of experimental data of recognition memory with different categories of verbal and pictorial stimuli. The model has a single free parameter and can be solved analytically. We then focus on recall and recognition memory of stories. This transition from discrete random lists to coherent continuous stimuli such as stories introduces a new challenge when it comes to the quantification and the analysis of the results. To address this, we have developed a pipeline that employs large language models and showed that it performs comparably to human evaluators. Using this tool we were able to show that recall scales linearly with recognition and story size for the range we examined. Finally, we discovered that when stories are presented in a scrambled manner, even though recall performance drops, subjects seem to reconstruct the material in their recall in alignment to the unscrambled version.
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Date:24MondayJune 2024Lecture
Foundations of Computer Science Seminar
More information Time 11:15 - 12:15Title Differentially Private Space-Efficient Algorithms for Frequency Moment Estimation in the Turnstile ModelLocation Jacob Ziskind BuildingLecturer Rachel Cummings
Columbia UniversityOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about The turnstile continual release model of differential priva...» The turnstile continual release model of differential privacy captures scenarios where a privacy-preserving real-time analysis is sought for a dataset evolving through additions and deletions. In typical applications of real-time data analysis, both the length of the stream T and the size of the universe |U| from which data come can be extremely large. This motivates the study of private algorithms in the turnstile setting using space sublinear in both T and |U|. In this paper, we give the first sublinear space differentially private algorithms for the fundamental problems of counting distinct elements and $ell_p$-frequency moment estimation in the turnstile streaming model. For counting distinct elements, our algorithm achieves O(T^{1/3}) space and additive error, and a (1 eta)-relative approximation for all eta in (0,1). Our result significantly improves upon the space requirements of the state-of-the-art for this problem in this model, which has a linear dependency in both T and |U|, while still achieving an additive error that is close to the known Omega(T^{1/4}) lower bound for arbitrary streams. This addresses an open question posed in prior work about designing low-memory mechanisms for this problem. For the more general problem of L_p-frequency moment estimation, our algorithm achieves an additive error and space of O(T^{1/3}), and a (1 eta)-relative approximation for all eta in (0,1). We also give a space lower bound for this problem, which shows that any algorithm that uses our techniques must use space Omega}(T^{1/3}). Joint work with Alessandro Epasto, Jieming Mao, Tamalika Mukherjee, Tingting Ou, and Peilin Zhong.
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Date:24MondayJune 2024Lecture
Midrasha on Groups Seminar
More information Time 11:15 - 13:00Title Spectral gap absorption principle for simple groupsLocation Jacob Ziskind BuildingLecturer Yuval Grofine
WeizmannOrganizer Department of MathematicsContact Abstract Show full text abstract about The aim of the talk is to show that simple groups over local...» The aim of the talk is to show that simple groups over local fields have a spectral gap absorption principle. That is, that if a representation that doesn't have almost invariant vectors is tensored with another representation, then the tensored representation still doesn't have almost invariant vectors. This property was conjectured by Uri Bader and Roman Sauer in their paper about unitary cohomology, and was proved there in some of the cases. We prove the general result. Such tensor products appear naturally when one works with restriction and induction of representations, and it is useful to know that the spectral gap is preserved.
I will (try to) give a survey of the rich and beautiful theory of representations of semisimple groups, and show how to use the celebrated Langlands classification theorem, as well as some more modern results, in order to prove the theorem.
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Date:24MondayJune 2024Lecture
Midrasha on Groups Seminar
More information Time 14:15 - 16:00Title Good locally testable codesLocation Jacob Ziskind BuildingLecturer Alex Lubotzky
WeizmannOrganizer Department of MathematicsContact Abstract Show full text abstract about An error-correcting code is locally testable (LTC) if there ...» An error-correcting code is locally testable (LTC) if there is a random tester that reads only a small number of bits of a given word and decides whether the word is in the code, or at least close to it. A long-standing problem asks if there exists such a code that also satisfies the golden standards of coding theory: constant rate and constant distance. Unlike the classical situation in coding theory, random codes are not LTC, so this problem is a challenge of a new kind.
We construct such codes based on what we call (Ramanujan) Left/Right Cayley square complexes. These objects seem to be of independent group-theoretic interest. The codes built on them are 2-dimensional versions of the expander codes constructed by Sipser and Spielman (1996).
The main result and lecture will be self-contained. But we hope also to explain how the seminal work of Howard Garland (1972) on the cohomology of quotients of the Bruhat–Tits buildings of p-adic Lie group has led to this construction (even though it is not used at the end).
Based on joint work with I. Dinur, S. Evra, R. Livne, and S. Mozes.
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Date:25TuesdayJune 2024Lecture
Mechano-regulation of gene expression in striated muscle
More information Time 10:00 - 11:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Daria Amiad-Pavlov
Perelman School of Medicine, University of PennsylvaniaOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about In recent years the cell nucleus emerged as a dynamic mechan...» In recent years the cell nucleus emerged as a dynamic mechanosensor capable of sensing and transducing mechanical signals into cellular responses to facilitate homeostasis and adaptation to changing environmental conditions. The constantly beating heart has a remarkable ability to adapt its structure and contractility in response to changes in mechanical load. I am introducing unique, live, and dynamic imaging approaches to investigate how nuclei in the mature heart can provide such mechano-protection and mechano-regulation of the genome. I will present a novel assay to couple cytoskeletal to nuclear strain transfer in the beating cardiomyocyte, and its further application to decipher mechanisms of nuclear damage in dilated cardiomyopathy caused by mutations in the LMNA gene (LMNA-DCM). This work pinpoints localized microtubule-dependent forces, but surprisingly not actomyosin contractility, as drivers of nuclear damage in LMNA-DCM, highlighting new therapeutic avenues. I will further discuss the role of mechanical signaling in spatial organization of the genome within the nucleus, to regulate transcriptionally active and repressed hubs, and downstream gene expression. -
Date:25TuesdayJune 2024Lecture
Molecular Manipulation of Heterogeneous Electrocatalysis Using Metal-Organic Frameworks
More information Time 11:00 - 12:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Idan Hod
Department of Chemistry at Ben-Gurion University of the Negev, BGUOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Electrocatalytically driven reactions that produce alternati...» Electrocatalytically driven reactions that produce alternative fuels and chemicals are considered as a useful means to store renewable
energy in the form of chemical bonds. in recent years there has been a significant increase in research efforts aiming to develop highly
efficient electrocatalysts that are able to drive those reactions. Yet, despite having made significant progress in this field, there is still a
need for developing new materials that could function both as active and selective electrocatalysts.
In that respect, Metal–Organic Frameworks (MOFs), are an emerging class of hybrid materials with immense potential in electrochemical
catalysis. Yet, to reach a further leap in our understanding of electrocatalytic MOF-based systems, one also needs to consider the welldefined
structure and chemical modularity of MOFs as another important virtue for efficient electrocatalysis, as it can be used to fine-tune
the immediate chemical environment of the active site, and thus affect its overall catalytic performance. Our group utilizes Metal-Organic
Frameworks (MOFs) based materials as a platform for imposing molecular approaches to control and manipulate heterogenous
electrocatalytic systems. In this talk, I will present our recent study on electrocatalytic schemes involving MOFs, acting as: a) electroactive
unit that incorporates molecular electrocatalysts, or b) non-electroactive MOF-based membranes coated on solid heterogenous catalysts.
