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אפריל 27, 2017

  • Date:15שנימאי 2023

    Systems Biology Seminar 2022-2023

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    שעה
    10:00 - 11:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מארגן
    מכון עזריאלי למערכות ביולוגיות
    צרו קשר
    הרצאה
  • Date:15שנימאי 2023

    Features and Objects as Perceptual Attractors: Theory, Paradigm, and Results from The Rat’s Whisker System

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    שעה
    11:00 - 12:15
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהGuy Nelinger, Student Seminar - PhD Thesis Defense
    Prof. Ehud Ahissar Lab
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about Perceivers experience the world around them as organized, wi...»
    Perceivers experience the world around them as organized, with sensory impressions clearly separated into entities. What makes a perceptual object, and what framework relates it to its composing features? A key insight is that under natural conditions, feature and object information is acquired actively, via sensor movements. Motor and sensory variables affect one another reciprocally, forming a closed-loop system. I therefore hypothesize that percepts signifying an object emerge when the motor-sensory loop’s dynamics converge towards a stable attractor. Using snout and whisker tracking data from freely-moving behaving rats, I outline such an attractor for object detection. I demonstrate that whisker-object contact elicits robust signals on a motor-sensory phase-plane, comprised of the derivatives of whisker base-angle and base-curvature. Over consecutive contact epochs, trajectories on the phase-plane converge to a specific area. The area is characterized by a basin of attraction during contact, more so than in free-air whisking. Differences in head-movement behavior are associated with proximity to the attractor, suggesting that the animal makes use of this proposed coding-scheme. Finally, to build upon these insights, I present a novel paradigm for the study of volitional perceptual exploration, in both rewarded and unrewarded contexts. It supports high-resolution study of motor-sensory development starting at birth, throughout task-learning and until mastery. Taken together, these results highlight a novel framework for the study of the perception of features and objects as motor-sensory attractors.
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  • Date:15שנימאי 2023

    KENDREW LECTURE: Computational Structural Biology in the Era of Deep Learning

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    שעה
    11:00 - 12:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. John Moult
    Institute of Bioscience and Biotechnology Research Department of Cell Biology and Molecular Genetics University of Maryland
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    צרו קשר
    הרצאה
  • Date:15שנימאי 2023

    Foundations of Computer Science Seminar

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    שעה
    11:15 - 12:30
    כותרת
    Bounded Weighted Edit Distance
    מיקום
    בניין יעקב זיסקינד
    מרצהTomasz Kociumaka
    Max Planck Institute for Informatics, Germany
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    צרו קשר
    הרצאה
  • Date:16שלישימאי 2023

    The application of ecological multilayer networks to microbial systems

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    שעה
    כל היום
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהDr. Shai Pilosof
    Department of Life Sciences, Ben Gurion University of the Negev
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:16שלישימאי 2023

    “ Spatiotemporal considerations of DNA damage and repair in the biogenesis of gene amplification in cancer”

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    שעה
    10:00 - 11:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהYifat Bar Or Snarski
    Dept. of Biomolecular Sciences - WIS
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    הרצאה
  • Date:16שלישימאי 2023

    Special Guest Seminar

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    שעה
    15:00 - 16:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Alexander Meissner & Prof. Paul Tesar
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:16שלישימאי 2023

    Special Guest Seminar

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    שעה
    15:00 - 15:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Alexander Meissner & Prof. Paul Tesar
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:17רביעימאי 2023

    Factors determining the early steps in the disease initiation of myeloproliferative neoplasms by the JAK2-mutated hematopoietic stem cell

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    שעה
    10:00 - 11:00
    מיקום
    בניין אולמן למדעי החיים
    מרצהProf. Dr. Radek C. Skoda
    Department of Biomedicine, University of Basel, Switzerland
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:17רביעימאי 2023

    CALR mutated myeloproliferative neoplasms: pathogenesis and targeted therapies

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    שעה
    11:00 - 12:00
    מיקום
    בניין אולמן למדעי החיים
    מרצהAssistant-Prof Robert Kralovics, Ph.D
    Department of Laboratory Medicine, Medical University of Vienna, Austria
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:18חמישימאי 2023

    Non-invasive Methods for Extracting Microstructural Information from Human Tissues: Implementation in a Clinical MRI Scanner

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    שעה
    09:30 - 10:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהAna Naamat
    Medical Physics Department, Bariloche Atomic Center
    מארגן
    מכון קלור לדימות וספקטרוסקופיה של תהודה מגנטית בעוצמות גבוהות
    צרו קשר
    תקצירShow full text abstract about Extracting quantitative information about tissue microstruct...»
    Extracting quantitative information about tissue microstructure using non-invasive methods is an exceptional challenge in understanding disease mechanisms and enabling early diagnosis of pathologies. Magnetic Resonance Imaging (MRI) is a promising and widely used technique to achieve this goal, but it still provides low resolution to reveal details of the microstructure. Recently, we have developed methods to produce images with quantitative information about the microstructure based on selective probing of spin dephasing induced by molecular diffusion restriction in cavities of the tissue microstructure [1-3]. The feasibility of the theoretical method has been demonstrated so far by first-principles experiments and simulations on typical size distributions of white matter in the mouse brain [3]. As a next step towards practical implementation, we have implemented this method in clinical scanners [4]. In this work, I present the challenges and preliminary results of this implementation in both phantoms and human volunteers. These results open up a new avenue for MRI to advance in extracting quantitative, and fast microstructural information from images.
    [1] A. Zwick, D. Sueter, G. Kurizki, G. A. Álvarez, Phys. Rev. Applied 14, 024088, (2020).
    [2] M. Capiglioni, A. Zwick, P. Jiménez, G. A. Álvarez. Proc. Intl. Soc. Mag. Reson. Med. 29, 2036 (2021)
    [3] M. Capiglioni, A. Zwick, P. Jiménez and G. A. Álvarez, Phys. Rev. Applied 15, 014045 (2021).
    [4] E. Saidman, A. Zwick, S. Tambalo, T. Feiweier, J. Jovicich, G. A. Álvarez. Proc. Intl. Soc. Mag. Reson. Med. (2023)

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  • Date:18חמישימאי 2023

    Physics Colloquium

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    שעה
    11:15 - 12:30
    כותרת
    TBA...
    מיקום
    בניין הפיזיקה ע"ש עדנה וק.ב. וייסמן
    מרצהProf. Eva Andre
    מארגן
    הפקולטה לפיזיקה
    צרו קשר
    תקצירShow full text abstract about TBA... ...»
    TBA...
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  • Date:18חמישימאי 2023

    Stromal and immune plasticity shape the metastatic microenvironment

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    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהProf. Neta Erez
    The Department of Pathology, Faculty of Medicine, Tel Aviv University
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    צרו קשר
    הרצאה
  • Date:20שבתמאי 202324רביעימאי 2023

    New Frontiers in Cardiac and Vascular Biology

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    שעה
    08:00 - 08:00
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    יושב ראש
    Karina Yaniv
    מארגן
    המחלקה לפיזיקה של מערכות מורכבות
    דף בית
    כנסים
  • Date:21ראשוןמאי 2023

    “ Programmatic and Deep Learning Analysis Pipelines for 4D-STEM Materials Science Experiments”

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    שעה
    11:00 - 12:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהDr. Colin Ophus
    Lawrence Berkeley National Laboratory, Berkeley
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    צרו קשר
    תקצירShow full text abstract about Scanning transmission electron microscopy (STEM) is one of t...»
    Scanning transmission electron microscopy (STEM) is one of the most popular materials science methods to characterize the structure and chemistry of nanoscale samples, owing to its high resolution and many flexible operating modes. In a conventional STEM experiment, we focus the electron beam down to a probe from nanometer to sub-angstrom scale, and scan it over the sample surface while recording diffracted signals which are transmitted through the specimen. STEM can also record analytic signals such as x-rays generated by the electron beam to measure composition, or energy loss of the transmitted electrons to probe the electronic structure of samples. Conventional STEM imaging detectors experiments produce only a few intensity values at each probe position, but modern high-speed detectors allow us to measure a full 2D diffraction pattern, over a grid of 2D probe positions, forming a four dimensional (4D)-STEM dataset. These 4D-STEM datasets record information about the local phase, orientation, deformation, and other parameters, for both crystalline and amorphous materials. 4D-STEM datasets can contain millions of images and therefore require highly automated and robust software codes to extract the target properties. In this talk, I will introduce our open source py4DSTEM analysis toolkit, and show how we use these codes to perform data-intensive studies of material properties over functional length scales. I will also demonstrate some applications of modern machine learning tools, to perform measurements on electron diffraction patterns where property signals have been scrambled by multiple scattering of the electron beam.
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  • Date:21ראשוןמאי 2023

    Determining past lake temperatures in saline lake systems using fluid inclusions: an example from the Dead Sea

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    שעה
    11:00 - 12:00
    מיקום
    בניין משפחת זוסמן
    מרצהNiels Brall
    The Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    תקצירShow full text abstract about In recent decades, various temperature proxies have been dev...»
    In recent decades, various temperature proxies have been developed and further established in the scientific community, at both low and high accuracy, however, not every method can be applied without restriction to all minerals or rocks. Evaporitic rocks, for example, are abundant chemical sediments at the Earth's surface that are deposited from supersaturated brines in marine, terrestrial, and lacustrine environments. Halite is the most abundant rock-forming mineral in this group, which during crystal formation entraps tiny water droplets (fluid inclusions, FIs) that store the chemical composition of the parent brine at a specific pressure-temperature dependent density. Such FIs are therefore excellent records of the original physicochemical conditions of the source brine.
    Brillouin spectroscopy (BS) is a novel laser-based technique that uses density fluctuations in FIs to directly measure entrapment temperatures and thus the initial brine temperature during crystal growth. In this seminar, the BS method will be introduced and two application cases will be presented using salt layers from the Dead Sea which were deposited during two interglacial periods. In addition to the basic principles, both the recommended sampling strategy and pitfalls along with associated limitations will be presented.
    The conclusion will be that the salt layers commonly deposited in the Dead Sea basin consist of two types that formed preferentially in summer (coarse-grained crystals) and winter (fine-grained crystals), which is mainly controlled by the degree of salt saturation of the lake water. Furthermore, it will be shown how (1) lake bottom temperatures have fluctuated seasonally (summer/winter), and that (2) paleo temperature trends can be reconstructed for an entire halite layer that was deposited during holomictic periods in the Dead Sea basin. This method is particularly promising for evaporites that formed near the surface if the material has not been affected by external processes such as tectonic burial/uplift, erosion, or mineral replacement.
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  • Date:21ראשוןמאי 2023

    Illuminating neural computations with structured light and sound wavefronts

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    שעה
    12:30 - 12:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Shy Shoham
    Neural Interface Engineering lab, NYU
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    הרצאה
  • Date:21ראשוןמאי 2023

    PhD Thesis Defense by Omer Goldman (Ayelet Erez Lab)

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    שעה
    13:00 - 13:00
    כותרת
    Non-liver cancers rewire liver metabolism in the host
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהOmer Goldman (Ayelet Erez Lab)
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:21ראשוןמאי 2023

    Brown Fat: From Basic Cell Biology to Human Health and Disease

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    שעה
    15:00 - 16:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Paul Cohen
    The Rockefeller University, NY, USA
    צרו קשר
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  • Date:22שנימאי 2023

    Ultrafast processes and the challenge of decoherence

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    שעה
    11:00 - 12:15
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Eberhard K. U. Gross
    Fritz Haber Center for Molecular Dynamics, HUJI, Jerusalem
    מארגן
    הפקולטה לכימיה
    דף בית
    צרו קשר
    תקצירShow full text abstract about A prominent goal of present-day condensed-matter physics is ...»
    A prominent goal of present-day condensed-matter physics is the design of electronic devices with ever faster switching times. As an example I will present the optically induced spin transfer between magnetic sublattices, the so-called OISTR effect, which allows the switching of magnetic textures on the scale of a femto-second or less. This effect was first predicted with real-time TDDFT and later confirmed in many experiments. To create from this effect a real-world device on has to face the problem of decoherence, i.e. the phenomenon that quantum systems tend to lose their quantumness due to interactions with the environment. For electrons, the principal source of decoherence is the non-adiabatic interaction with nuclear degrees of freedom, i.e. with an “environment” that cannot be removed. In fact, the paradigm of electronic-structure theory where electrons move in the static Coulomb potential of clamped nuclei, while useful in the ground state, is an idealization hardly ever satisfied in dynamical processes. Non-adiabaticity, i.e. effects of the coupled motion of electrons and nuclei beyond the Born-Oppenheimer approximation are found everywhere. In this lecture, the exact factorization will be presented as a universal approach to understand and, ultimately, control non-adiabatic effects, in particular decoherence, from an ab-initio perspective.
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