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אפריל 29, 2015

  • Date:01שלישידצמבר 2015

    Sponges - ancient organisms innovative research

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    שעה
    11:15 - 11:15
    מיקום
    בניין אולמן למדעי החיים
    מרצהDr. Ray Keren
    Department of Zoology, Tel Aviv University
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:01שלישידצמבר 2015

    Systematic dissection of the role of dendritic cells in driving immune responses: from pathogen sensing to tumor elimination

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    שעה
    11:30 - 11:30
    מיקום
    בניין וולפסון למחקר ביולוגי
    מרצהDr. Oren Parnas
    Broad Institute
    מארגן
    המחלקה לאימונולוגיה מערכתית
    צרו קשר
    הרצאה
  • Date:01שלישידצמבר 2015

    Blood sweat and tears: Social chemosignaling in human health and disease

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    שעה
    12:30 - 12:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Noam Sobel
    Department of Neurobiology, WIS
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about Most animals communicate using social chemosignals, namely c...»
    Most animals communicate using social chemosignals, namely chemicals emitted by one member of the species, which then produce chemical and behavioral changes in other members of the species. Such communication is prevalent in insects and terrestrial mammals, and mounting evidence implies that it is also common in human behavior, albeit primarily at a subliminal level. Human social chemosignals are responsible for a host of effects ranging from driving menstrual synchrony in women to conveying fear across individuals. Here I will describe our findings on mechanisms of human chemosignaling in both health and disease. Based on these findings I will argue that in contrast to common notions, humans are highly olfactory animals.
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  • Date:02רביעידצמבר 2015

    Sphingosine-1-phosphate: a key regulator of the link between inflammation and cancer

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    שעה
    11:00 - 11:00
    מיקום
    בניין וולפסון למחקר ביולוגי
    מרצהProf. Sarah Spiegel
    Professor and Chair, Department of Biochemistry and Molecular Biology Virginia Commonwealth University School of Medicine, USA
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:02רביעידצמבר 2015

    Do rare decays point to physics beyond the Standard Model

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    שעה
    11:00 - 11:00
    מיקום
    Technion, Lidow 502
    מרצהSebastian Jaeger
    University of Sussex
    מארגן
    המחלקה לפיזיקה של חלקיקים ואסטרופיזיקה
    דף בית
    צרו קשר
    הרצאה
  • Date:02רביעידצמבר 2015

    The Emergence of Pattern in Random Processes

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    שעה
    11:15 - 12:30
    מיקום
    בניין לפיזיקה על-שם נלה וליאון בנוזיו
    מרצהWill Newman
    מארגן
    מרכז לאסטרופיסיקה עש נלה וליאון בנוזיו
    צרו קשר
    תקצירShow full text abstract about We consider both time series as well as spatial distribution...»
    We consider both time series as well as spatial distributions (in 1-4 dimensions).
    In the first, we observe that time series for individual and independently deviating random variables can manifest pattern through the emergence of peak-to-peak sequences that are visible to the eye yet fail all Fourier analysis schemes and reveal a seeming periodicity of 3-events per cycle. We note that this can explain observations of apparent cycles in mammalian animal populations. We consider models, as well, based on the Langevin equation of kinetic theory and the Smolouchowski relation that present circumstances where the apparent period can vary from 3-4 and, for a special subclass of problems, to periods between 2 and 3. We explore how cataloged observational data from global earthquake catalogues, magnetospheric AL index observations, Old Faithful Geyser eruption data, and the performance of the Standard & Poor's 500 index (percent daily variation) manifest different degrees of statistical agreement with the theory we derived. We present a simple model for many mammalian population cycles whose underlying phenomenological basis has strong biological implications.
    We then employ directed graphs to explore nearest-neighbor relationships and isolate the character of spatial clustering in 1-4 dimension. We observe that the one-dimensional problem is formally equivalent to that presented by peak-to-peak sequences in time series and also demonstrates a mean number of points per cluster of 3 in one dimension. We then take the first moment of each of the clusters formed, and observed that they too form clusters.
    We observe the emergence of a hierarchy of clusters and the emergence of universal cluster numbers, analogous to branching ratios and, possibly, Feigenbaum numbers. These, in turn, are related to fractals as well as succularity and lacunarity, although the exact nature of this connection has not been identified. Finally, we show how hierarchical clustering emerging from random distributions may help provide an explanation for observations of hierarchical clustering in cosmology via the virial theorem and simulation results relating to the gravitational stabilization in a self-similar way of very large self-gravitating ensembles.
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  • Date:02רביעידצמבר 2015

    Towards a No-Lose Theorem for Naturalness

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    שעה
    13:00 - 13:00
    מיקום
    Technion, Lidow 502
    מרצהGabriel Lee
    Technion
    מארגן
    המחלקה לפיזיקה של חלקיקים ואסטרופיזיקה
    צרו קשר
    תקצירShow full text abstract about http://arxiv.org/abs/1509.04284 ...»
    http://arxiv.org/abs/1509.04284
    הרצאה
  • Date:02רביעידצמבר 2015

    הקאמרטה הישראלית ירושלים -גברת הביטי

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    שעה
    20:00 - 22:00
    מיקום
    אודיטוריום מיכאל סלע
    צרו קשר
    אירועי תרבות
  • Date:03חמישידצמבר 2015

    Single cell analysis of HSV-1 infection (Virology Club meeting)

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    שעה
    10:00 - 11:00
    כותרת
    Oren Kobiler from TAU will talk about "Single cell analysis of HSV-1 infection"
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהDr. Oren Kobiler
    Single cell analysis of HSV-1 infection
    צרו קשר
    הרצאה
  • Date:03חמישידצמבר 2015

    Perturbations to worm sleep, weak and strong

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    שעה
    11:15 - 12:30
    מיקום
    בניין הפיזיקה ע"ש עדנה וק.ב. וייסמן
    מרצהDavid Biron
    Chicago University
    מארגן
    הפקולטה לפיזיקה
    צרו קשר
    תקצירShow full text abstract about Sleep may be universal in the animal kingdom. Yet, the roles...»
    Sleep may be universal in the animal kingdom. Yet, the roles of sleep in organizing living mat-ter and the underlying reason for this universality remain controversial. Fundamental ques-tions under debate include the boundaries of this universality (do all animals sleep?), natural history (when did sleep evolve?), and core function (what for, originally?). The roundworm C. elegans is the simplest model system in which these questions can be addressed.

    A key feature distinguishing sleep from other states of decreased activity is its intricate home-ostatic regulation: following disruptions, ‘restoring forces’ extend or modify sleep to compen-sate for the loss. This talk will describe measurements of three regimes of perturbations to worm sleep. We have shown that weak and intermediate perturbations reveal distinct man-ners in which small losses of worm sleep are compensated for. In addition, we have shown that stronger perturbations, causing substantial but nonlethal loss to worms sleep, inflicts long-term deficits. These deficits and the protective mechanisms that mitigate them are ex-pected to be directly linked to functions of sleep in this (phylogenetically) ancient model.

    These findings add to the list of similarities between worm and vertebrate sleep and open the door to a better understanding of sleep’s core functions.
    סימפוזיונים
  • Date:03חמישידצמבר 2015

    Long Range Gene Regulation during Vertebrate Development and Evolution

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    שעה
    12:00 - 12:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Denis Duboule
    School of Life Sciences, Federal Institute of Technology, Lausanne, Switzerland
    צרו קשר
    הרצאה
  • Date:03חמישידצמבר 2015

    הרצאה שנתית במדעי הרוח על שם חיים ויצמן

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    שעה
    19:30 - 21:00
    כותרת
    הגאופוליטיקה המשתנה של המזרח התיכון
    מיקום
    אודיטוריום מיכאל סלע
    מרצהProf. Uzi Rabi
    Head of The Moshe Dayan Center for Middle Eastern and African studies, Tel Aviv University
    מארגן
    יד חיים וייצמן
    צרו קשר
    הרצאה
  • Date:05שבתדצמבר 2015

    בן בן ברוך - סטנד אפ

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    שעה
    21:00 - 22:30
    מיקום
    אודיטוריום מיכאל סלע
    דף בית
    צרו קשר
    אירועי תרבות
  • Date:06ראשוןדצמבר 2015

    Depositional controls on preserved sulfur isotope signals in modern and ancient marine sediments

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    שעה
    11:00 - 11:00
    מיקום
    בניין משפחת זוסמן
    מרצהDavid Fike
    Washington University
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    הרצאה
  • Date:06ראשוןדצמבר 2015

    Chemical Physics Lunch Club Seminar

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    שעה
    12:30 - 12:30
    כותרת
    Understanding Isomerization - Insight from hybrid QM/MM molecular dynamics simulations
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהIgor Schapiro
    Hebrew University and Max Planck Institute for Chemical Energy Conversion, Mülheim an der Ruhr, Germany
    מארגן
    המחלקה לפיזיקה כימית וביולוגית
    צרו קשר
    תקצירShow full text abstract about The primary event of vision in the vertebrate eye is the hig...»
    The primary event of vision in the vertebrate eye is the highly selective and efficient photoisomerization of 11-cis-retinal protonated Schiff base (RPSB) bound to the visual protein rhodopsin (Rh). With a ~100% selectivity, ~65% quantum yield, and ~200 fs product appearance time, this isomerization is considered the archetype of a photochemical reaction optimized by nature to achieve a specific molecular response.
    Recently, we have used a combination of a quantum chemical and a classical force field method (QM/MM) to resolve the isomerization mechanism for the RPSB chromophore in Rh[1]. Important stereoelectronic factors were found that determine the outcome of the photoisomerization. The same protocol was also applied to investigate the photochemical mechanism of the newly discovered Anabaena Sensory Rhodopsin[2] and of a biomimetic molecular switch that works in solution[3].
    Using the same computational protocol we have also studied the ground state (thermal) isomerization.[4] The results of the simulations explain the molecular mechanism of thermal noise in rod photoreceptors and make a direct link to experimentally found correlations for night vision.
    References:
    [1] Schapiro I, Ryazantsev M N, Frutos L M, Ferré N, Lindh R, Olivucci M. J. Am. Chem. Soc. (2011), 133, 3354.
    [2] Schapiro I, Ruhman S. Biochim Biophys Acta. (2014), 1837, 589.
    [3] Léonard J, Schapiro I, Briand J, Fusi S, Paccani R R, Olivucci M, Haacke S. Chem. Eur. J. (2012), 18, 15296.
    [4] Gozem S, Schapiro I, Ferré N, Olivucci M. Science (2012), 33, 6099.
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  • Date:06ראשוןדצמבר 2015

    To be announced

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    שעה
    13:00 - 13:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:07שנידצמבר 2015

    The 4th Israeli Meeting on Zebrafish as a Model for Biomedical Research

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    שעה
    08:30 - 16:45
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    דף בית
    כנסים
  • Date:07שנידצמבר 2015

    Regulating Meiotic Recombination in Plants

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    שעה
    11:15 - 11:15
    מיקום
    בניין אולמן למדעי החיים
    מרצהProfessor Gregory P. Copenhaver
    Department of Biology, University of North Carolina at Chapel Hill, USA, Director of Graduate Studies, (Molecular Cellular and Developmental Biology), Editor-in-Chief, PLOS Genetics
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:07שנידצמבר 2015

    Cancer Club Seminar - Signaling & communication in breast cancer

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    שעה
    14:00 - 15:00
    מיקום
    בניין תשתיות ושירותי מחקר על-שם ראול וגרציאלה דה פיצ'וטו
    מרצהStefan Wiemann
    DKFZ Heidelberg, Germany
    מארגן
    המחלקה לאימונולוגיה ורגנרציה ביולוגית
    צרו קשר
    הרצאה
  • Date:07שנידצמבר 2015

    Model of antibiotic action on bacterial population growth

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    שעה
    14:15 - 14:15
    מיקום
    בניין הפיזיקה ע"ש עדנה וק.ב. וייסמן
    מרצהMartin Evans
    University of Edinburgh
    מארגן
    המחלקה לפיזיקה של מערכות מורכבות
    צרו קשר
    תקצירShow full text abstract about In this talk I will describe a simple model for the growth o...»
    In this talk I will describe a simple model for the growth of a bacterial population under the challenge of ribosome-targeting antibiotics. The model is statistical physics-like in that it makes a coarse-grained description of the growth process, reduced to three variables within the bacterial cell - the antibiotic concentration, the concentration of ribosomes bound to antibiotics and the concentration of unbound ribosomes. Furthermore, there is biological input from empirically established physiological constraints which relate the three variables. Remarkably the model can explain several observations concerning antibiotic action and bacterial growth rate. In particular the growth-dependent bacterial susceptibility is controlled by a single, `universal' parameter and the extreme behaviours correspond to the phenomenological classification into bactericidal and bacteriostatic antibiotics. If time allows I will describe how the predictions of the model are backed up by experimental studies.
    Reference:
    Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics Philip Greulich, Matthew Scott, Martin R. Evans, Rosalind J. Allen Molecular Systems Biology 11:796 (2015)

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