Protein Analysis Publications

  1. Miron T., Rabinkov A., Peleg E., Rosenthal T., Mirelman D. & Wilchek M. (2003). Allylmercapto-captopril, a new antihypertensive drug, its preparation and properties.  American Journal of Hypertension. 2003 May , 16 (5):128A-128A.
  2. Millard C., Shnyrov V., Newstead S., Shin I., Roth E., Silman I. & Weiner L. (2003). Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones.  Protein Science. 2003 Oct , 12 (10):2337-2347.
  3. Miron T., Mironchik M., Mirelman D., Wilchek M. & Rabinkov A. (2003). Inhibition of tumor growth by a novel approach: In situ allicin generation using targeted alliinase delivery.  Molecular Cancer Therapeutics. 2003 Dec , 2 (12):1295-1301.
  4. Shin I., Wachtel E., Roth E., Bon C., Silman I. & Weiner L. (2002). Thermal denaturation of Bungarus fasciatus acetylcholine sterase: Is aggregation a driving force in protein unfolding?.  Protein Science. 2002 Aug , 11 (8):2022-2032.
  5. Miron T., Shin I., Feigenblat G., Weiner L., Mirelman D., Wilchek M. & Rabinkov A. (2002). A spectrophotometric assay for allicin, alliin, and aliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates.  Analytical Biochemistry. 2002 Aug , 307 (1):76-83.
  6. Miron T., Shin I., Feigenblat G., Weiner L., Mirelman D., Wilchek M. & Rabinkov A. (2002). A spectrophotometric assay for allicin, alliin, and aliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates.  Analytical Biochemistry. 2002 Aug , 307 (1):76-83.
  7. Shimon L., Rabinkov A., Miron T., Mirelman D., Wilchek M. & Frolow F. (2002). Alliin lyase (alliinase) from garlic (Allium sativum): crystallization and preliminary X-ray characterization.  Acta Crystallographica Section D-Biological Crystallography. 2002 Aug , 58 :1335-1337.
  8. Elkayam A., Mirelman D., Peleg E., Wilchek M., Miron T., Rabinkov A., Sadetzki S. & Rosenthal T. (2001). The effects of allicin and enalapril in fructose-induced hyperinsulinemic hyperlipidemic hypertensive rats.  American Journal of Hypertension. 2001 Apr , 14 (4):377-381.
  9. De Ferrari F. G., Canales M., Shin I., Weiner L., Silman I. & Inestrosa N. (2001). A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation.  Biochemistry. 2001 Sept , 40 (35):10447-10457.
  10. Tchernychev B., Rabinkov A., Miron T. & Wilchek M. (2000). Natural antibodies against alliinase in human serum and polyclonal antibodies elicited in rabbit share the same immunogenic determinants.  Immunology Letters. 2000 Jan , 71 (1):43-47.
  11. Miron T., Rabinkov A., Mirelman D., Wilchek M. & Weiner L. (2000). The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity.  Biochimica Et Biophysica Acta-Biomembranes. 2000 Jan , 1463 (1):20-30.
  12. Rabinkov A., Miron T., Mirelman D., Wilchek M., Glozman S., Yavin E. & Weiner L. (2000). S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties.  Biochimica Et Biophysica Acta-Molecular Cell Research. 2000 Dec , 1499 (2-Jan):144-153.
  13. Hirsch K., Danilenko M., Giat J., Miron T., Rabinkov A., Wilchek M., Mirelman D., Levy J. & Sharoni Y. (2000). Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation.  Nutrition And Cancer-An International Journal. 2000, 38 (2):245-254.
  14. Abramovitz D., Gavri S., Harats D., Levkovitz H., Mirelman D., Miron T., Eilat-Adar S., Rabinkov A., Wilchek M., Eldar M. & Vered Z. (1999). Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet.  Coronary Artery Disease. 1999 Oct , 10 (7):515-519.
  15. Miron T., Rabinkov A., Mirelman D., Weiner L. & Wilchek M. (1998). A spectrophotometric assay for allicin and alliinase (alliin lyase) activity: Reaction of 2-nitro-5-thiobenzoate with thiosulfinates.  Analytical Biochemistry. 1998 Dec , 265 (2):317-325.
  16. Rabinkov A., Miron T., Konstantinovski L., Wilchek M., Mirelman D. & Weiner L. (1998). The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins.  Biochimica Et Biophysica Acta-General Subjects. 1998 Feb , 1379 (2):233-244.
  17. Shin I., Silman I., Bon C. & Weiner L. (1998). Liposome-catalyzed unfolding of acetylcholinesterase from Bungarus fasciatus.  Biochemistry. 1998 Mar , 37 (13):4310-4316.
  18. Ankri S., Miron T., Rabinkov A., Wilchek M. & Mirelman D. (1997). Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica.  Antimicrobial Agents and Chemotherapy. 1997 Oct , 41 (10):2286-2288.
  19. Shin I., Kreimer D., Silman I. & Weiner L. (1997). Membrane-promoted unfolding of acetylcholinesterase: A possible mechanism for insertion into the lipid bilayer.  Proceedings of the National Academy of Sciences of the United States of America. 1997 Apr , 94 (7):2848-2852.
  20. Shin I., Silman I. & Weiner L. (1996). Interaction of partially unfolded forms of Torpedo acetylcholinesterase with liposomes.  Protein Science. 1996 Jan , 5 (1):42-51.