Targeted Metabolomics Publications

  1. Gnainsky Y., Zfanya N., Elgart M., Omri E., Brandis A., Mehlman T., Itkin M., Malitsky S., Adamski J. & Soen Y. (2021). Systemic Regulation of Host Energy and Oogenesis by Microbiome-Derived Mitochondrial Coenzymes.  Cell Reports. 2021 Jan , 34 (1).
  2. Bartok O., Pataskar A., Nagel R., Laos M., Goldfarb E., Hayoun D., Levy R., Körner P. R., Kreuger I. Z., Champagne J., Zaal E. A., Bleijerveld O. B., Huang X., Kenski J., Wargo J., Brandis A., Levin Y., Mizrahi O., Alon M., Lebon S., Yang W., Nielsen M. M., Stern-Ginossar N., Altelaar M., Berkers C. R., Geiger T., Peeper D. S., Olweus J., Samuels Y. & Agami R. (2020). Anti-tumour immunity induces aberrant peptide presentation in melanoma.  Nature. 2020 Dec , .
  3. Sela I., Meir A. Y., Brandis A., Krajmalnik-Brown R., Zeibich L., Chang D., Dirks B., Tsaban G., Kaplan A., Rinott E., Zelicha H., Arinos S., Ceglarek U., Isermann B., Lapidot M., Green R. & Shai I. (2020). Wolffia globosa–mankai plant-based protein contains bioactive vitamin b12 and is well absorbed in humans.  Nutrients. 2020 Oct , 12 (10).
  4. Keshet R., Lee J. S., Adler L., Iraqi M., Ariav Y., Lim L. Q. J., Lerner S., Rabinovich S., Oren R., Katzir R., Tishler H. W., Stettner N., Goldman O., Landesman H., Galai S., Kuperman Y., Kuznetsov Y., Brandis A., Mehlman T., Malitsky S., Itkin M., Koehler S. E., Zhao Y., Talsania K., Shen T., Peled N., Ulitsky I., Porgador A., Ruppin E. & Erez A. (2020). Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.  Nature Cancer. 2020 Sept , 1 (9):894-908.
  5. Brekelmans J., Veugen J., Rieff K., Dickman M. M., Goz A., Wolffs P., Brandis A., Berendschot T. T., Nuijts R. M., Scherz A. & Marcovich A. L. (2020). Enzymatic digestion of porcine corneas cross-linked by hypo-and hyperosmolar formulations of riboflavin/ultraviolet A or WST11/near-infrared light.  Translational Vision Science and Technology. 2020 Sept , 9 (10).
  6. Marcovich A. L., Brekelmans J., Brandis A., Samish I., Pinkas I., Preise D., Sasson K., Feine I., Goz A., Dickman M. M., Nuijts R. M. & Scherz A. (2020). Decreased riboflavin impregnation time does not increase the risk for endothelial phototoxicity during corneal cross-linking.  Translational Vision Science and Technology. 2020 May , 9 (6).
  7. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul , 142 (27):11734-11742.
  8. Blacher E., Bashiardes S., Shapiro H., Rothschild D., Mor U., Dori-Bachash M., Kleimeyer C., Moresi C., Harnik Y., Zur M., Zabari M., Brik R. B., Kviatcovsky D., Zmora N., Cohen Y., Bar N., Levi I., Amar N., Mehlman T., Brandis A., Biton I., Kuperman Y., Tsoory M., Alfahel L., Harmelin A., Schwartz M., Israelson A., Arike L., Johansson M. E. V., Hansson G. C., Gotkine M., Segal E. & Elinav E. (2019). Potential roles of gut microbiome and metabolites in modulating ALS in mice.  Nature. 2019 Aug , 572 (7770):474-480.
  9. , Lerner S., Eilam R., Kuperman Y., Tsoory M., Brandis A., Segal M., Chen A. & Erez A. (2019). ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus.  Cell Reports. 2019 Nov , 29 (8):2144-2153.e7.
  10. Garcia-Campos M. A., Edelheit S., Toth U., Safra M., Shachar R., Viukov S., Winkler R., Nir R., Lasman L., Brandis A., Hanna J. H., Rossmanith W. & Schwartz S. (2019). Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling.  Cell. 2019 Jul , 178 (3):731-747.
  11. Golan K., Kumari A., Kollet O., Khatib-Massalha E., Subramaniam M. D., Ferreira Z. S., Avemaria F., Rzeszotek S., Garcia-Garcia A., Xie S., Flores-Figueroa E., Gur-Cohen S., Itkin T., Ludin-Tal A., Massalha H., Bernshtein B., Ciechanowicz A. K., Brandis A., Mehlman T., Bhattacharya S., Bertagna M., Cheng H., Petrovich-Kopitman E., Janus T., Kaushansky N., Cheng T., Sagi I., Ratajczak M. Z., Mendez-Ferrer S., Dick J. E., Markus R. P. & Lapidot T. (2018). Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance.  Cell Stem Cell. 2018 Oct , 23 (4):572-585.
  12. Lee J. S., Adler L., Karathia H., Carmel N., Rabinovich S., Auslander N., Keshet R., Stettner N., Silberman A., Agemy L., Helbling D., Eilam R., Sun Q., Brandis A., Malitsky S., Itkin M., Weiss H., Pinto S., Kalaora S., Levy R., Barnea E., Admon A., Dimmock D., Stern-Ginossar N., Scherz A., Nagamani S. C. S., Unda M., Wilson D. M., Elhasid R., Carracedo A., Samuels Y., Hannenhalli S., Ruppin E. & Erez A. (2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.  Cell. 2018 Sept , 174 (6):1559-1570.
  13. Markovic S., Fages A., Roussel T., Hadas R., Brandis A., Neeman M. & Frydman L. (2018). Placental physiology monitored by hyperpolarized dynamic 13C magnetic resonance.  Proceedings of the National Academy of Sciences of the United States of America. 2018 Mar , 115 (10):E2429-E2436.
  14. Stettner N., Rosen C., Bernshtein B., Gur-Cohen S., Frug J., Silberman A., Sarver A., Carmel-Neiderman N. N., Eilam R., Biton I., Pevsner-Fischer M., Zmora N., Brandis A., Halpern K. B., Mazkereth R., di Bernardo D., Brunetti-Pierri N., Premkumar M. H., Dank G., Nagamani S. C. S., Jung S., Harmelin A. & Erez A. (2018). Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer.  Cell Reports. 2018 May , 23 (7):1962-1976.
  15. Wolf Y., Boura-Halfon S., Cortese N., Haimon Z., Shalom H. S., Kuperman Y., Kalchenko V., Brandis A., David E., Segal-Hayoun Y., Chappell-Maor L., Yaron A. & Jung S. (2017). Brown-adipose-tissue macrophages control tissue innervation and homeostatic energy expenditure.  Nature Immunology. 2017 Jun , 18 (6):665-674.
  16. Despotovic D., Brandis A., Savidor A., Levin Y., Fumagalli L. & Tawfik D. (2017). Diadenosine tetraphosphate (Ap4A) - an E-coli alarmone or a damage metabolite?.  FEBS Journal. 2017 Jul , 284 (14):2194-2215.
  17. Marcovich A. L. & Brandis A. (2017). Riboflavin, Ultraviolet Light, and the Photochemical Reaction.  . 2017, :27-32.
  18. Geller L. T., Barzily-Rokni M., Danino T., Jonas O. H., Shental N., Nejman D., Gavert N., Zwang Y., Cooper Z. A., Shee K., Thaiss C. A., Reuben A., Livny J., Avraham R., Frederick D. T., Ligorio M., Chatman K., Johnston S. E., Mosher C. M., Brandis A., Fuks G., Gurbatri C., Gopalakrishnan V., Kim M., Hurd M. W., Katz M., Fleming J., Maitra A., Smith D. A., Skalak M., Bu J., Michaud M., Trauger S. A., Barshack I., Golan T., Sandbank J., Flaherty K. T., Mandinova A., Garrett W. S., Thayer S. P., Ferrone C. R., Huttenhower C., Bhatia S. N., Gevers D., Wargo J. A., Golub T. R. & Straussman R. (2017). Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.  Science. 2017 Sept , 357 (6356):1156-1160.
  19. Brekelmans J., Goz A., Dickman M. M., Brandis A., Sui X., Wagner H. D., Nuijts R. M. M. A., Scherz A. & Marcovich A. L. (2017). Corneal Stiffening by a Bacteriochlorophyll Derivative With Dextran and Near-Infrared Light: Effect of Shortening Irradiation Time up to 1 Minute.  Cornea. 2017 Nov , 36 (11):1395-1401.
  20. Halpern K. B., Shenhav R., Matcovitch-Natan O., Toth B., Lemze D., Golan M., Massasa E. E., Baydatch S., Landen S., Moor A. E., Brandis A., Giladi A., Stokar-Avihail A., David E., Amit I. & Itzkovitz S. (2017). Single-cell spatial reconstruction reveals global division of labour in the mammalian liver.  Nature. 2017 Feb , 542 (7641):352-+.