Targeted Metabolomics Publications

  1. Garrett A., Darzi N., Deshmukh A., Rosenfeld N., Goldman O., Adler L., Bab-Dinitz E., Singer O., Hassani Najafabadi A., Wong C. W., Bose S., Randon P. M., Bustamante F., Larios R., Brandis A., Mehlman T., Smaglo B., Chang P., Oliva J., Haymaker C., Nagawekar L., Wu S. R., Huang Y., Shen A., Vora A., Padilla J. F., Pfeffer A., Sutherland G., Starr M., Zimmers T., Zhu Y., Morizio J., Erez A. & Shen X. (2025). Vagal blockade of the brain-liver axis deters cancer-associated cachexia.  Cell. 2025 Oct 16 , 188 (21):6044-6063.e24.
  2. Vogels D. H., Brekelmans J., Mohren R., Vos N. R., Brandis A., Marcovich A. L., Cillero-Pastor B., Scherz A., LaPointe V. L. & Dickman M. M. (2025). Proteomics Reveals Mechanisms of Delayed Keratoconus Progression: A Study of Corneas Following Two Light-Activated Crosslinking Treatments.  Investigative Ophthalmology and Visual Science. 2025 Jan , 66 (1).
  3. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  4. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  5. Bahat A., Itzhaki E., Weiss B., Tolmasov M., Tsoory M., Kuperman Y., Brandis A., Shurrush K. A. & Dikstein R. (2024). Lowering mutant huntingtin by small molecules relieves Huntingtons disease symptoms and progression.  EMBO Molecular Medicine. 2024 Mar 14 , 16 (3):523-546.
  6. Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z. (2024). LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.  Nature Communications. 2024 Aug 8 , 15 .
  7. Moraïs S., Mazor M., Tovar-Herrera O., Zehavi T., Zorea A., Ifrach M., Bogumil D., Brandis A., Walter J., Elia N., Gur E. & Mizrahi I. (2024). Plasmid-encoded toxin defence mediates mutualistic microbial interactions.  Nature Microbiology. 2024 Jan , 9 (1):108-119.
  8. Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z. (2024). LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.  Nature Communications. 2024 Aug 8 , 15 .
  9. Schlichter Kadosh Y., Muthuraman S., Nisaa K., Ben-Zvi A., Karsagi Byron D. L., Shagan M., Brandis A., Mehlman T., Gopas J., Saravana Kumar R. & Kushmaro A. (2024). Pseudomonas aeruginosa quorum sensing and biofilm attenuation by a di-hydroxy derivative of piperlongumine (PL-18).  Biofilm. 2024 Dec , 8 .
  10. Garb J., Amitai G., Lu A., Ofir G., Brandis A., Mehlman T., Kranzusch P. J. & Sorek R. (2024). The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products.  PLOS ONE. 2024 Apr 18 , 19 (4 ).
  11. Zung N., Aravindan N., Boshnakovska A., Valenti R., Preminger N., Jonas F., Yaakov G., Willoughby M. M., Homberg B., Keller J., Kupervaser M., Dezorella N., Dadosh T., Wolf S. G., Itkin M., Malitsky S., Brandis A., Barkai N., Fernández-Busnadiego R., Reddi A. R., Rehling P., Rapaport D. & Schuldiner M. (2024). The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites.  BioRxiv. 2024 May 12 , .
  12. Garb J., Amitai G., Lu A., Ofir G., Brandis A., Mehlman T., Kranzusch P. J. & Sorek R. (2024). The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products.  PLOS ONE. 2024 Apr 18 , 19 (4 ).
  13. Schlichter Kadosh Y., Muthuraman S., Nisaa K., Ben-Zvi A., Karsagi Byron D. L., Shagan M., Brandis A., Mehlman T., Gopas J., Saravana Kumar R. & Kushmaro A. (2024). Pseudomonas aeruginosa quorum sensing and biofilm attenuation by a di-hydroxy derivative of piperlongumine (PL-18).  Biofilm. 2024 Dec , 8 .
  14. Allouche-Arnon H., Montrazi E. T., Subramani B., Fisler M., Spigel I., Frydman L., Mehlman T., Brandis A., Harris T. & Bar-Shir A. (2024). A Genetically Engineered Reporter System Designed for 2H-MRI Allows Quantitative In Vivo Mapping of Transgene Expression.  Journal of the American Chemical Society. 2024 Nov 20 , 146 (46):31624-31632.
  15. Brandis A., Roy D., Das I., Sheves M. & Eisenbach M. (2024). Uncommon opsin's retinal isomer is involved in mammalian sperm thermotaxis.  Scientific Reports. 2024 May 10 , 14 .
  16. Marcovich A. L. & Brandis A. (2024). Riboflavin, Ultraviolet Light, and the Photochemical Reaction.  . 2024 Jan 1 , :27-32.
  17. Stroganov S., Harris T., Alyagor L., Ben Moyal L., Plitman Mayo R., Golani O., Hirsch D., Ben-Dor S., Brandis A., Mehlman T., Kovo M., Biron-Shental T., Dekel N. & Neeman M. (2024). The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.  eLife. 2024 Feb 5 , 13 .
  18. Allouche-Arnon H., Montrazi E. T., Subramani B., Fisler M., Spigel I., Frydman L., Mehlman T., Brandis A., Harris T. & Bar-Shir A. (2024). A Genetically Engineered Reporter System Designed for 2H-MRI Allows Quantitative In Vivo Mapping of Transgene Expression.  Journal of the American Chemical Society. 2024 Nov 20 , 146 (46):31624-31632.
  19. Stroganov S., Harris T., Alyagor L., Ben Moyal L., Plitman Mayo R., Golani O., Hirsch D., Ben-Dor S., Brandis A., Mehlman T., Kovo M., Biron-Shental T., Dekel N. & Neeman M. (2024). The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.  eLife. 2024 Feb 5 , 13 .
  20. Suzzi S., Croese T., Ravid A., Gold O., Clark A. R., Medina S., Kitsberg D., Adam M., Vernon K. A., Kohnert E., Shapira I., Malitsky S., Itkin M., Brandis A., Mehlman T., Salame T. M., Colaiuta S. P., Cahalon L., Slyper M., Greka A., Habib N. & Schwartz M. (2023). N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimers disease mouse model.  Nature Communications. 2023 Mar 9 , 14 (1).