Targeted Metabolomics Publications

  1. Allouche-Arnon H., Khersonsky O., Tirukoti N. D., Peleg Y., Dym O., Albeck S., Brandis A., Mehlman T., Avram L., Harris T., Yadav N. N., Fleishman S. J. & Bar-Shir A. (2022). Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.  Nature biotechnology. 2022 Jul , 40 (7):1143-1149.
  2. Koh E., Brandis A. & Fluhr R. (2022). Plastid and cytoplasmic origins of 1O2-mediated transcriptomic responses.  Frontiers in Plant Science. 2022 Nov 7 , 13 .
  3. Serger E., Luengo-Gutierrez L., Chadwick J. S., Kong G., Zhou L., Crawford G., Danzi M. C., Myridakis A., Brandis A., Bello A. T., Müller F., Sanchez-Vassopoulos A., De Virgiliis F., Liddell P., Dumas M. E., Strid J., Mani S., Dodd D. & Di Giovanni S. (2022). The gut metabolite indole-3 propionate promotes nerve regeneration and repair.  Nature (London). 2022 Jun 22 , 607 :585-592.
  4. Lerner S., Eilam R., Adler L., Tsoory M., Brandis A. & Erez A. (2021). ASL expression in ALDH1A1 + neurons in the substantia nigra metabolically contributes to neurodegenerative phenotype.  Human Genetics. 2021 Oct , 140 (10):1471-1485.
  5. Koh E., Cohen D., Brandis A. & Fluhr R. (2021). Attenuation of cytosolic translation by RNA oxidation is involved in singlet oxygen-mediated transcriptomic responses.  Plant, Cell and Environment. 2021 Nov , 44 (11):3597-3615.
  6. Tal N., Morehouse B. R., Millman A., Stokar-Avihail A., Avraham C., Fedorenko T., Yirmiya E., Herbst E., Brandis A., Mehlman T., Oppenheimer-Shaanan Y., Keszei A. F., Shao S., Amitai G., Kranzusch P. J. & Sorek R. (2021). Cyclic CMP and cyclic UMP mediate bacterial immunity against phages.  Cell. 2021 Nov 11 , 184 (23):5728-5739.e16.
  7. Fluhr L., Mor U., Kolodziejczyk A. A., Dori-Bachash M., Leshem A., Itav S., Cohen Y., Suez J., Zmora N., Moresi C., Ayalon N., Valdés-Mas R., Molina S., Hornstein S., Karbi H., Kviatcovsky D., Livne A., Bukimer A., Eliyahu-Miller S., Metz A., Brandis A., Mehlman T., Kuperman Y., Tsoory M., Stettner N., Harmelin A., Shapiro H. & Elinav E. (2021). Gut microbiota modulates weight gain in mice after discontinued smoke exposure.  Nature (London). 2021 Dec 23 , 600 (7890):713-719.
  8. Dierks D., Garcia-Campos M. A., Uzonyi A., Safra M., Edelheit S., Rossi A., Sideri T., Varier R. A., Brandis A., Stelzer Y., van Werven F., Scherz-Shouval R. & Schwartz S. (2021). Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution.  Nature Methods. 2021 Sept 3 , 18 (9):1060-1067.
  9. Gnainsky Y., Zfanya N., Elgart M., Omri E., Brandis A., Mehlman T., Itkin M., Malitsky S., Adamski J. & Soen Y. (2021). Systemic Regulation of Host Energy and Oogenesis by Microbiome-Derived Mitochondrial Coenzymes.  Cell Reports. 2021 Jan 5 , 34 (1).
  10. Panayotis N., Freund P. A., Marvaldi L., Shalit T., Brandis A., Mehlman T., Tsoory M. M. & Fainzilber M. (2021). β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice.  Cell Reports Medicine. 2021 May 18 , 2 (5).
  11. Fortus D., Ofek-Geva E., Vinker-Shuster M., Mehlman T., Malitsky S., Brandis A. & Yeshayahu Y. (2021). The Onset of Puberty and Adolescents’ Motivation to Learn Science.  Adolescent Health. 2021, .
  12. Bartok O., Pataskar A., Nagel R., Laos M., Goldfarb E., Hayoun D., Levy R., Körner P., Kreuger I. Z. M., Champagne J., Zaal E. A., Bleijerveld O. B., Huang X., Kenski J., Wargo J., Brandis A., Levin Y., Mizrahi O., Alon M., Lebon S., Yang W., Nielsen M. M., Stern-Ginossar N., Altelaar M., Berkers C. R., Geiger T., Peeper D. S., Olweus J., Samuels Y. & Agami R. (2021). Anti-tumour immunity induces aberrant peptide presentation in melanoma.  Nature. 2021 Feb 11 , 590 (7845):332-337.
  13. Even A., Morelli G., Turchetto S., Shilian M., Bail R. L., Laguesse S., Krusy N., Brisker A., Brandis A., Inbar S., Chariot A., Saudou F., Dietrich P., Dragatsis I., Brone B., Broix L., Rigo J., Weil M. & Nguyen L. (2021). ATP-citrate lyase promotes axonal transport across species.  Nature Communications. 2021 Oct 7 , 12 (1).
  14. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul 8 , 142 (27):11734-11742.
  15. Marcovich A. L., Brekelmans J., Brandis A., Samish I., Pinkas I., Preise D., Sasson K., Feine I., Goz A., Dickman M. M., Nuijts R. M. & Scherz A. (2020). Decreased riboflavin impregnation time does not increase the risk for endothelial phototoxicity during corneal cross-linking.  Translational Vision Science and Technology. 2020 May , 9 (6).
  16. Brekelmans J., Veugen J., Rieff K., Dickman M. M., Goz A., Wolffs P., Brandis A., Berendschot T. T., Nuijts R. M., Scherz A. & Marcovich A. L. (2020). Enzymatic digestion of porcine corneas cross-linked by hypo-and hyperosmolar formulations of riboflavin/ultraviolet A or WST11/near-infrared light.  Translational Vision Science and Technology. 2020 Sept 3 , 9 (10).
  17. Sela I., Meir A. Y., Brandis A., Krajmalnik-Brown R., Zeibich L., Chang D., Dirks B., Tsaban G., Kaplan A., Rinott E., Zelicha H., Arinos S., Ceglarek U., Isermann B., Lapidot M., Green R. & Shai I. (2020). Wolffia globosa–mankai plant-based protein contains bioactive vitamin b12 and is well absorbed in humans.  Nutrients. 2020 Oct , 12 (10).
  18. Keshet R., Lee J. S., Adler L., Iraqi M., Ariav Y., Lim L. Q. J., Lerner S., Rabinovich S., Oren R., Katzir R., Tishler H. W., Stettner N., Goldman O., Landesman H., Galai S., Kuperman Y., Kuznetsov Y., Brandis A., Mehlman T., Malitsky S., Itkin M., Koehler S. E., Zhao Y., Talsania K., Shen T., Peled N., Ulitsky I., Porgador A., Ruppin E. & Erez A. (2020). Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.  Nature Cancer. 2020 Sept , 1 (9):894-908.
  19. Blacher E., Bashiardes S., Shapiro H., Rothschild D., Mor U., Dori-Bachash M., Kleimeyer C., Moresi C., Harnik Y., Zur M., Zabari M., Brik R. B., Kviatcovsky D., Zmora N., Cohen Y., Bar N., Levi I., Amar N., Mehlman T., Brandis A., Biton I., Kuperman Y., Tsoory M., Alfahel L., Harmelin A., Schwartz M., Israelson A., Arike L., Johansson M. E. V., Hansson G. C., Gotkine M., Segal E. & Elinav E. (2019). Potential roles of gut microbiome and metabolites in modulating ALS in mice.  Nature. 2019 Aug 22 , 572 (7770):474-480.
  20. Garcia-Campos M. A., Edelheit S., Toth U., Safra M., Shachar R., Viukov S., Winkler R., Nir R., Lasman L., Brandis A., Hanna J. H., Rossmanith W. & Schwartz S. (2019). Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling.  Cell. 2019 Jul 25 , 178 (3):731-747.