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Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression. Nature biotechnology. 2022 Jan , 40 (7).(2022).
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Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea. The journal of Biological chemistry. 2022 Mar , 298 (5).(2022).
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The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.). RSC Chemical Biology. 2022 Mar , 3 (3):320-333.(2022).
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Community-Wide Experimental Evaluation of the PROSS Stability-Design Method. Journal of Molecular Biology. 2021 Jun , 433 (13):166964-166964.(2021).
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Evolution of CPEB4 Dynamics Across its Liquid–Liquid Phase Separation Transition. The Journal of Physical Chemistry B. 2021 Dec , 125 (47):12947-12957.(2021).
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Highly active rubiscos discovered by systematic interrogation of natural sequence diversity. The EMBO Journal. 2020 Sept , 39 (18).(2020).
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Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques. Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan , 117 (1):395-404.(2020).
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Efficient targeted degradation via reversible and irreversible covalent PROTACs. Journal of the American Chemical Society. 2020 Jul , 142 (27):11734-11742.(2020).
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Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements. ChemPhysChem. 2019 Jul , 20 (14):1860-1868.(2019).
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Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces. PLoS Computational Biology. 2019 Aug , 15 (8).(2019).
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Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor. Cell Chemical Biology. 2019 Jan , 26 (1):98 - 108.(2019).
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Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution. Nature Communications. 2018 Sept , 9 .(2018).
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Highly active enzymes by automated combinatorial backbone assembly and sequence design. Nature Communications. 2018 Jul , 9 .(2018).
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Ultrahigh specificity in a network of computationally designed protein-interaction pairs. Nature Communications. 2018 Dec , 9 (1).(2018).
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Manipulating the Folding Landscape of a Multi-Domain Protein. Journal of Physical Chemistry B. 2018 Dec , 122 (49):11030-11038.(2018).
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Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli. PLoS ONE. 2018 Sept , (9).(2018).
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Principles for computational design of binding antibodies. Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct , 114 (41):10900-10905.(2017).
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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Molecular Cell. 2016 Jul , 63 (2):337-346.(2016).
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AcpM, the Meromycolate Extension Acyl Carrier Protein of Mycobacterium tuberculosis, Is Activated by the 4 '-Phosphopantetheinyl Transferase PptT, a Potential Target of the Multistep Mycolic Acid Biosynthesis. Biochemistry. 2015 Apr , 54 (14):2360-2371.(2015).
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