Protein Purification Publications

  1. Baran D., Pszolla M. G., Lapidoth G. D., Norn C., Dym O., Unger T., Albeck S., Tyka M. D. & Fleishman S. J. (2017). Principles for computational design of binding antibodies.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct 10 , 114 (41):10900-10905.
  2. Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R. (2017). Communication between viruses guides lysis-lysogeny decisions.  Nature. 2017 Jan 26 , 541 (7638):488-493.
  3. Goldenzweig A., Goldsmith M., Hill S. E., Gertman O., Laurino P., Ashani Y., Dym O., Unger T., Albeck S., Prilusky J., Lieberman R. L., Aharoni A., Silman I., Sussman J., Tawfik D. & Fleishman S. J. (2016). Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.  Molecular Cell. 2016 Jul 21 , 63 (2):337-346.
  4. Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A. (2015). A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.  ChemBioChem. 2015 Jul 6 , 16 (10):1415-1419.
  5. Zimhony O., Schwarz A., Raitses-Gurevich M., Peleg Y., Dym O., Albeck S., Burstein Y. & Shakked Z. (2015). AcpM, the meromycolate extension Acyl carrier protein of mycobacterium tuberculosis, is activated by the 4′-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.  Biochemistry. 2015 Apr 14 , 54 (14):2360-2371.
  6. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). [Cover Profile] Sensing Protein Surfaces with Targeted Fluorescent Receptors..  Chemistry (Weinheim an der Bergstrasse, Germany). 2015 Nov , 21 (45):15873-15873.
  7. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). Sensing Protein Surfaces with Targeted Fluorescent Receptors.  Chemistry (Weinheim an der Bergstrasse, Germany). 2015 Nov 1 , 21 (45):15981-15987.
  8. Sobolev V., Edelman M., Dym O., Unger T., Albeck S., Kirma M. & Galili G. (2013). Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.  Acta Crystallographica Section F-Structural Biology And Crystallization Communications. 2013 Feb , 69 (2):84-89.
  9. Bharat T. A. M., Zbaida D., Eisenstein M., Frankenstein Z., Mehlman T., Weiner L., Sorzano C. O. S., Barak Y., Albeck S., Briggs J. A. G., Wolf S. G. & Elbaum M. (2013). Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA.  Structure. 2013 Jul 2 , 21 (7):1158-1167.
  10. Krieg E., Albeck S., Weissman H., Shimoni E. & Rybtchinski B. (2013). Separation, Immobilization, and Biocatalytic Utilization of Proteins by a Supramolecular Membrane.  PLoS ONE. 2013 May 10 , 8 (5).
  11. Khersonsky O., Kiss G., Röthlisberger D., Dym O., Albeck S., Houk K. N., Baker D. & Tawfik D. S. (2012). Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.  Proceedings of the National Academy of Sciences of the United States of America. 2012 Jun 26 , 109 (26):10358-10363.
  12. Hama S., Soran H., Albeck S., Charlton-Menys V., Yadav R., Liu Y., France M., Tawfiq D. & Durrington P. (2012). HIGH PARAOXONASE-1 HDL IS MORE EFFECTIVE THAN LOW PARAOXONASE-1 HDL IN IMPEDING LDL OXIDATION IN VITRO.  Atherosclerosis. 2012 Aug , 223 (2):529-529.
  13. Khersonsky O., Roethlisberger D., Wollacott A. M., Murphy P., Dym O., Albeck S., Kiss G., Houk K. N., Baker D. & Tawfik D. (2011). Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution.  Journal of Molecular Biology. 2011 Apr , 407 (3):391-412.
  14. Li M., Greenblatt H. M., Dym O., Albeck S., Pais A., Gunanathan C., Milstein D., Degani H. & Sussman J. (2011). Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators.  Journal of Medicinal Chemistry. 2011 May 26 , 54 (10):3575-3580.
  15. Cohen S., Albeck S., Ben-Dov E., Cahan R., Firer M., Zaritsky A. & Dym O. (2011). Cyt1Aa toxin: Crystal structure reveals implications for its membrane-perforating function.  Journal of Molecular Biology. 2011 Nov 4 , 413 (4):804-814.
  16. Karanicolas J., Com J. E., Chen I., Joachimiak L. A., Dym O., Peck S. H., Albeck S., Unger T., Hu W., Liu G., Delbecq S., Montelione G. T., Spiegel C. P., Liu D. R. & Baker D. (2011). A De Novo Protein Binding Pair By Computational Design and Directed Evolution.  Molecular Cell. 2011 Apr 22 , 42 (2):250-260.
  17. Siton O., Ideses Y., Albeck S., Unger T., Bershadsky A. D., Gov N. S. & Bernheim-Groswasser A. (2011). Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.  Current Biology. 2011 Dec 20 , 21 (24):2092-2097.
  18. Carlessi R., Levin-Salomon V., Ciprut S., Bialik S., Berissi H., Albeck S., Peleg Y. & Kimchi A. (2011). GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.  EMBO Reports. 2011 Sept , 12 (9):917-923.
  19. Unger T., Dym O., Albeck S., Jacobovitch Y., Bernehim R., Marom D., Pisanty O. & Breiman A. (2010). Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain.  Journal of Structural and Functional Genomics. 2010 Jun , 11 (2):113-23.
  20. Khersonsky O., Röthlisberger D., Dym O., Albeck S., Jackson C. J., Baker D. & Tawfik D. S. (2010). Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the ke07 series.  Journal of Molecular Biology. 2010, 396 (4):1025-1042.