DNA Manipulation Publications

  1. Peleg Y., Vincentelli R., Collins B. M., Chen K., Livingstone E. K., Weeratunga S., Leneva N., Guo Q., Remans K., Perez K., Bjerga G. E., Larsen Ø., Vaněk O., Skořepa O., Jacquemin S., Poterszman A., Kjaer S., Christodoulou E., Albeck S., Dym O., Ainbinder E., Unger T., Schuetz A., Matthes S., Bader M., de Marco A., Storici P., Semrau M. S., Stolt-Bergner P., Aigner C., Suppmann S., Goldenzweig A. & Fleishman S. J. (2021). Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.  Journal of Molecular Biology. 2021 Jun , 433 (13):166964-166964.
  2. Adams E. M., Pezzotti S., Ahlers J., Rüttermann M., Levin M., Goldenzweig A., Peleg Y., Fleishman S. J., Sagi I. & Havenith M. (2021). Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction.  JACS Au. 2021 Jun , 1 (7):1076-1085.
  3. Peleg Y., Vincentelli R., Collins B. M., Chen K., Livingstone E. K., Weeratunga S., Leneva N., Guo Q., Remans K., Perez K., Bjerga G. E., Larsen Ø., Vaněk O., Skořepa O., Jacquemin S., Poterszman A., Kjaer S., Christodoulou E., Albeck S., Dym O., Ainbinder E., Unger T., Schuetz A., Matthes S., Bader M., de Marco A., Storici P., Semrau M. S., Stolt-Bergner P., Aigner C., Suppmann S., Goldenzweig A. & Fleishman S. J. (2021). Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.  Journal of Molecular Biology. 2021 Jun , 433 (13):166964-166964.
  4. Kolářová L., Zahradník J., Huličiak M., Mikulecký P., Peleg Y., Shemesh M., Schreiber G. & Schneider B. (2021). De novo developed protein binders mimicking Interferon lambda signaling.  The FEBS journal. 2021 Nov , .
  5. Israeli H., Degtjarik O., Fierro F., Chunilal V., Gill A. K., Roth N. J., Botta J., Prabahar V., Peleg Y., Chan L. F., Ben-Zvi D., McCormick P. J., Niv M. Y. & Shalev-Benami M. (2021). Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.  Science (American Association for the Advancement of Science). 2021 Apr , .
  6. Giannoulis A., Feintuch A., Unger T., Amir S. & Goldfarb D. (2021). Monitoring the Conformation of the Sba1/Hsp90 Complex in the Presence of Nucleotides with Mn(II)-Based Double Electron–Electron Resonance.  The journal of physical chemistry letters. 2021 Dec , :12235-12241.
  7. Tarayrah-Ibraheim L., Maurice E. C., Hadary G., Ben-Hur S., Kolpakova A., Braun T., Peleg Y., Yacobi-Sharon K. & Arama E. (2021). DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.  Nature Communications. 2021 Apr , 12 (1).
  8. Ofir-Birin Y., Ben Ami Pilo H., Camacho A. C., Rudik A., Rivkin A., Revach O., Nir N., Tamin T. B., Karam P. A., Kiper E., Peleg Y., Nevo R., Solomon A., Havkin-Solomon T., Rojas A., Rotkopf R., Porat Z., Avni D., Schwartz E., Zillinger T., Hartmann G., Di Pizio A., Ben Quashie N., Dikstein R., Gerlic M., Torrecilhas A. C., Levy C., Hoen E. N. M. N., Bowie A. G. & Regev-Rudzki N. (2021). Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.  Nature Communications. 2021 Aug , 12 .
  9. Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M. (2021). Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes.  Journal of the American Chemical Society. 2021 Oct , 143 (41):17261-17275.
  10. Singh A., Erijman A., Noronha A., Kumar H., Peleg Y., Yarden Y. & Shifman J. M. (2021). Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma.  The journal of Biological chemistry. 2021 Dec , 297 (6).
  11. Hatai J., Prasad P. K., Lahav-Mankovski N., Oppenheimer-Low N., Unger T., Sirkis Y. F., Dadosh T., Motiei L. & Margulies D. (2021). Assessing changes in the expression levels of cell surface proteins with a turn-on fluorescent molecular probe.  Chemical Communications. 2021 Feb , 57 (15):1875-1878.
  12. Seal M., Jash C., Jacob R., Feintuch A., Harel Y., Albeck S., Unger T. & Goldfarb D. (2021). Evolution of CPEB4 Dynamics Across its Liquid–Liquid Phase Separation Transition.  The Journal of Physical Chemistry B. 2021 Dec , 125 (47):12947-12957.
  13. Rosenthal M., Metzl-Raz E., Buergi J., Yifrach E., Drwesh L., Fadel A., Peleg Y., Rapaport D., Wilmanns M., Barkai N., Schuldiner M. & Zalckvar E. (2020). Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.  Proceedings of the National Academy of Sciences of the United States of America. 2020 Sept , 117 (35):21432-21440.
  14. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul , 142 (27):11734-11742.
  15. Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D. (2020). Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.  Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan , 117 (1):395-404.
  16. Davidi D., Shamshoum M., Guo Z., Bar‐On Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., Mueller‐Cajar O. & Milo R. (2020). Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.  The EMBO Journal. 2020 Sept , 39 (18).
  17. Lahav-Mankovski N., Prasad P. K., Oppenheimer-Low N., Raviv G., Dadosh T., Unger T., Salame T. M., Motiei L. & Margulies D. (2020). Decorating bacteria with self-assembled synthetic receptors.  Nature Communications. 2020 Mar , 11 (1).
  18. Prabahar V., Afriat-Jurnou L., Paluy I., Peleg Y. & Noy D. (2020). New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.  FEBS Journal. 2020 Mar , 287 (5):991-1004.
  19. Meltzer H., Marom E., Alyagor I., Mayseless O., Berkun V., Segal-Gilboa N., Unger T., Luginbuhl D. & Schuldiner O. (2019). Tissue-specific (ts) CRISPR as an efficient strategy for in vivo screening in Drosophila.  Nature Communications. 2019 May , 10 .
  20. Cardenas P. D., Sonawane P. D., Heinig U., Jozwiak A., Panda S., Abebie B., Kazachkova Y., Pliner M., Unger T., Wolf D., Ofner I., Vilaprinyo E., Meir S., Davydov O., Gal-On A., Burdman S., Giri A., Zamir D., Scherf T., Szymanski J., Rogachev I. & Aharoni A. (2019). Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases.  Nature Communications. 2019 Nov , 10 .