Bioinformatics: LSCF Publications

  1. Cohen E., Fiterman M., Itkowitz B., Elaobda A., Rotkopf R., Eldada M. & Benkovich V. (2026). Surgical alternatives for treatment of developmental dysplasia of the hip in children aged 14 years: does open reduction improve the outcomes?.  European Journal of Orthopaedic Surgery and Traumatology. 2026 Dec , 36 .
  2. Landi E., van Beusekom E., Ben-Dor S., Albert S., Dickman M. M., LaPointe V. L. & van Bokhoven H. (2026). Biallelic rescue of CTG18.1 in two Fuchs endothelial corneal dystrophyderived iPSC lines (SCTCi047-A-2, SCTCi046-A-2) following a two-step gene editing strategy.  Stem Cell Research. 2026 Sept , 95 .
  3. Lebow M., Rotkopf R., Malik E., Amitai M., Weizman A., Krieger O., Geyshin A., Israel A., Merzon E., Magen E., Vinker S., Nuttman-Shwartz O. & Chen A. (2026). Intensity and exposure proximity as determinants of differential stress-related health outcomes.  Molecular Psychiatry. 2026 Mar 6 , 31 (7):3955-3964.
  4. Tishler H., Ziman S., Cheng K., Wang K., Sanghvi N., Adler L., Stelzer G., Maniriho H., Dassa B., Bab-Dinitz E., Levi M., Galai S., Goldman O., Ariav Y., Darzi N., Ezagouri S., Nimni N., Rosenfeld N., Rotkopf R., Brandis A., Mehlman T., Oren R., Zerbib M., Kuznetsov Y., Donzelli S., Blandino G., Seger R., Ruppin E. & Erez A. (2026). Inhibition of Tumor Microenvironment-Driven JAK-STAT Signaling Enhances Response to Arginine Deprivation Therapy in Triple-Negative Breast Cancer.  Cells. 2026 Jan , 15 (1).
  5. Tishler H., Ziman S., Cheng K., Wang K., Sanghvi N., Adler L., Stelzer G., Maniriho H., Dassa B., Bab-Dinitz E., Levi M., Galai S., Goldman O., Ariav Y., Darzi N., Ezagouri S., Nimni N., Rosenfeld N., Rotkopf R., Brandis A., Mehlman T., Oren R., Zerbib M., Kuznetsov Y., Donzelli S., Blandino G., Seger R., Ruppin E. & Erez A. (2026). Inhibition of Tumor Microenvironment-Driven JAK-STAT Signaling Enhances Response to Arginine Deprivation Therapy in Triple-Negative Breast Cancer.  Cells. 2026 Jan , 15 (1).
  6. Tishler H., Ziman S., Cheng K., Wang K., Sanghvi N., Adler L., Stelzer G., Maniriho H., Dassa B., Bab-Dinitz E., Levi M., Galai S., Goldman O., Ariav Y., Darzi N., Ezagouri S., Nimni N., Rosenfeld N., Rotkopf R., Brandis A., Mehlman T., Oren R., Zerbib M., Kuznetsov Y., Donzelli S., Blandino G., Seger R., Ruppin E. & Erez A. (2026). Inhibition of Tumor Microenvironment-Driven JAK-STAT Signaling Enhances Response to Arginine Deprivation Therapy in Triple-Negative Breast Cancer.  Cells. 2026 Jan , 15 (1).
  7. Gallardo-Navarro O., Arbel-Goren R., Dassa B., August E. & Stavans J. (2026). Oxygen Field Dynamics in Bioconvection and the Spatial Organization of Multispecies Aerobic Bacteria.  PRX Life. 2026 Aug , 4 (3).
  8. Abou Karam P., Kiper E., Ziv T., Yadid S., Kozela E., Zharoni N., Nevo R., Alfandari D., Otesh H., Cruz Camacho A., Lubelsky Y., Rotkopf R., Weizman E., Cossin M., Rosenhek-Goldian I., Petrovich-Kopitman E., Porat Z., Shoshani O., Ulitsky I., Levy C., Melamed Z. & Regev-Rudzki N. (2026). Nuclear import of malaria RNA rewires splicing in host immune cells.  Cell Reports. 2026 Feb 24 , 45 (2).
  9. Lebon S., Habshush Menachem A., Davidzohn N., Katz A., Wigoda N., Braun T., Yahalomi D., Rotkopf R., Holiar V., Dadosh T., Levin-Zaidman S., Dezorella N., Goliand I., Kupervaser M., Leebhoff S., Blumberger N., Hoffman D., Grunewald M., Levin Y., Haberman Y., Hofree M. & Biton M. (2026). An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection.  Nature Immunology. 2026 Jul , 27 (7):1404-1417.
  10. Gumpert N., Sagie S., Arnedo-Pac C., Babu T., Weller C., Gonzalez-Perez A., Wang Y., Todó L. M., Levy R., Chen X., Greenberg P., Dayan-Rubinov M., Yakubovich E., Wasserman-Bartov T., Zerbib M., Gong J., Rebernick R. J., Tercero A. O., Muriel L. A., Benedek G., Kedmi M., Oren R., Ben-Dor S., Levin Y., Troyanskaya O. G., Munzur A. D., Wyatt A. W., Cieslik M. P., Quigley D. A., Van Allen E. M., Anandasabapathy N., Mateo J., Yang X., Martínez-Jiménez F., Lopez-Bigas N. & Samuels Y. (2026). Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer.  Cancer Discovery. 2026 Feb 6 , 16 (2):OF1-OF20.
  11. Rachmian-Cooper N., Shmulevich R., Akiva H., Pokorna S., Dassa B., Cherqui U., Malitsky S., Itkin M., Kliger B. A., Goliand I., Salame T. M. & Krizhanovsky V. (2026). Senescent cells accumulate lipid droplets.  Aging. 2026, 18 :768-786.
  12. Cabillon N. A. R., Koch L., Mizrahi N., Ben-Dor S., Segev-Hadar A., Meiri Ashkenazi I., Alupo G., Bitan A. & Biran J. (2026). Cocaine- and amphetamine-regulated transcripts in two percomorphs: evolutionary conservation and energy-status dependent responses.  Frontiers in Endocrinology. 2026 Jun 30 , 17 .
  13. Zoler E., Miodownik I., Ben-Dor S., Harari D., Zahradnik J., Afek A. & Schreiber G. (2026). IRF1 is a context-dependent homeostatic gatekeeper of basal immunity and antiviral readiness.  Journal of Biological Chemistry. 2026 Feb , 302 (2).
  14. Sadeh M., Schatz D., Ben-Dor S., Mizrachi A., Graff van Creveld S., Zafrin A. & Vardi A. (2026). Metacaspases contribute to the cellular response to heat stress in a marine diatom.  New Phytologist. 2026 May , 250 (4):2357-2367.
  15. Eyal Z., Deis R., Gorelick-Ashkenazi A., Barzilay Y., Broder Y., Kellum A. P., Varsano N., Hartstein M., Sorrentino A., Rotkopf R., Kaplan-Ashiri I., Rechav K., Metzler R., Houben L., Kronik L., Rez P. & Gur D. (2026). pH variations enable guanine crystal formation within iridosomes.  Nature Chemical Biology. 2026 Jan , 22 (1):19-27.
  16. Alon T., Ross M., Spirer J., Silva P. D. S., Rosov A., Lifshitz L., Kra G., Gershoni M., Malitsky S., Itkin M., Rotkopf R. & Moallem U. (2026). Lipidomics of allantoic fluid collected by allantocentesis indicates a possible mechanism underlying partial litter loss in multifetal pregnancies of ewes.  Scientific Reports. 2026 Dec , 16 .
  17. Shvefel S. C., Pai J. A., Cao Y., Pal L. R., Bartok O., Levy R., Zemanek M. J., Weller C., Herzog E., Yao W., Hiam-Galvez K. J., Cheng K., Yin Y., Du P. P., Raposo C. J., Gumpert N., Welti M., Martínez Gómez J. M., Sella F., Yakubovich E., Orr I., Ben-Dor S., Oren R., Fellus-Alyagor L., Golani O., Brenner O. J., Salame T. M., Zerbib M., Goliand I., Ranmar D., Savchenko I., Ketrarou N., Schäffer A. A., Dahan R., Levesque M. P., Ruppin E., Satpathy A. T. & Samuels Y. (2025). Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma.  Cancer Discovery. 2025 Mar 1 , 15 (3):553-577.
  18. Shpitzen S., Rosen H., Ben-Zvi A., Meir K., Levin G., Gudgold A., Ben Dor S., Haffner R., Zwas D. R., Leibowitz D., Slaugenhaupt S. A., Banin E., Mizrachi R., Obolensky A., Levine R. A., Gilon D., Leitersdorf E., Tessler I., Reshef N. & Durst R. (2025). Characterization of LTBP2 mutation causing mitral valve prolapse.  European Heart Journal Open. 2025 Jan 1 , 5 (1).
  19. Mizrachi A., Sadeh M., Ben-Dor S., Dym O., Ku C., Feldmesser E., Zarfin A., Brunson J. K., Allen A. E., Jinkerson R. E., Schatz D. & Vardi A. (2025). Cathepsin X is a conserved cell death protein involved in algal response to environmental stress.  Current Biology. 2025 May 19 , 35 (10):2240-2255.
  20. Kiper E., Ben Hur D., Alfandari D., Camacho A. C., Wani N. A., Efrat G. D., Morandi M. I., Goldsmith M., Rotkopf R., Kamyshinsky R., Deshmukh A., Binte Zulkifli N. E., Asmari N., Penedo M., Fantner G., Porat Z., Azuri I., Rosenhek-Goldian I., Chitnis C. E., Shai Y. & Regev-Rudzki N. (2025). Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism.  Journal of Biological Chemistry. 2025 Apr , 301 (4).