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Abstract: A key issue in the use of nanomaterials is controlling how they interact with themselves and with the outer world. Our research program focuses on the tailoring of nanoparticles of surfaces for a variety of applications, coupling the atomic-level control provided by organic synthesis with the fundamental principles of supramolecular chemistry. Using these engineered nanoparticles, we are developing particles for biological applications, in particular delivery and sensing. This talk will focus on the interfacing of nanoparticles with biosystems, and will discuss our use of nanoparticles for delivery applications including our studies of small molecule, nucleic acid, and protein delivery. This presentation will also feature the use of nanoparticles for diagnostic applications, including the use of array-based sensing paradigms for the detection and identification of cancer.

The notion of a quantum jump is almost synonymous, in the public mind, with all things quantum mechanical. It comes to us as an echo from the very earliest days of the “old quantum theory”. My talk will trace the quantum jump from these early beginnings to its use as a building block of stochastic Shroedinger equations in modern quantum optics. Experi-ments with trapped ions and microwave photons in a box provide simple illustrations of the ideas.