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ינואר 01, 2013

  • Date:04שנינובמבר 2024

    Midrasha on Groups Seminar

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    שעה
    14:15 - 16:00
    כותרת
    Dynamical tilings, mean dimension, and shift embeddability for actions of amenable groups
    מיקום
    בניין יעקב זיסקינד
    מרצהPetr Naryshkin
    Alfréd Rényi Institute of Mathematics
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about We start by introducing the problem of shift embeddability a...»
    We start by introducing the problem of shift embeddability and recalling the theorem of Gutman, Qiao, and Tsukamoto, which gives a satisfying answer for actions of Z^d. For actions of arbitrary amenable groups, we define property URPC (which asks for the existence of certain tilings) and show how it is useful for the question at hand. We then describe how it can often be obtained from an a priori much weaker condition. Throughout the talk, we highlight the new ideas that were required to go beyond the case of Z^d.
    הרצאה
  • Date:05שלישינובמבר 2024

    Seminar for PhD thesis defense

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    שעה
    11:30 - 11:30
    כותרת
    Epithelial Tissue Regeneration by Compensatory Proliferation After Ionizing Radiation is Controlled by the Apical Caspase 9 Ortholog Dronc
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהTslil Braun
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:06רביעינובמבר 2024

    Machine Learning and Statistics Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Spectral Transformers
    מיקום
    בניין יעקב זיסקינד
    מרצהElad Hazan
    Princeton
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    צרו קשר
    תקצירShow full text abstract about We'll discuss a new technique for sequence modeling for...»
    We'll discuss a new technique for sequence modeling for prediction tasks with long range dependencies and fast inference/generation. At the heart of the method is a new formulation for state space models (SSMs) based on learning linear dynamical systems with the spectral filtering algorithm. 
    This gives rise to a novel sequence prediction architecture we call a spectral state space model.  
    Spectral state space models have two primary advantages. First, they have provable robustness properties as their performance depends on neither the spectrum of the underlying dynamics nor the dimensionality of the problem. Second, these models are constructed with fixed convolutional filters that do not require learning while still outperforming SSMs in both theory and practice.The resulting models are evaluated on synthetic dynamical systems and long-range prediction tasks of various modalities. These evaluations support the theoretical benefits of spectral filtering for tasks requiring very long range memory.

    The talk will be self-contained, but here is a link to more information about spectral filtering. 
    הרצאה
  • Date:06רביעינובמבר 2024

    LS Luncheon

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    שעה
    12:00 - 14:00
    כותרת
    From blind spots to insights: uncovering mechanisms of epiProteome regulation
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהProf. Yifat Merbl
    צרו קשר
    הרצאה
  • Date:07חמישינובמבר 2024

    Stromal and Immune Plasticity Shape The Metastatic Microenvironment

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    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהProf. Neta Erez
    Faculty of Medical & Health Sciences, Tel Aviv University.
    מארגן
    מרכז הבינתחומי לחקר סרטן עש מורוס
    צרו קשר
    הרצאה
  • Date:10ראשוןנובמבר 202413רביעינובמבר 2024

    the 76th Annual General meeting of the International Board 2024

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    שעה
    כל היום
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    צרו קשר
    מועצת המנהלים הבינלאומית
  • Date:10ראשוןנובמבר 2024

    Special Guest Seminar

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    שעה
    11:00 - 12:00
    כותרת
    Central simple representations and superelliptic jacobians
    מיקום
    בניין יעקב זיסקינד
    מרצהYuri Zarkhin
    Pennsylvania State University
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about Let p be an odd prime and f(x)  a polynomial of degree at le...»
    Let p be an odd prime and f(x)  a polynomial of degree at least 5 with complex coefficients and without repeated roots. Suppose that all the coefficients of f(x) lie in a subfield K such that: 

    1)      K contains a primitive p-th root of unity
    הרצאה
  • Date:10ראשוןנובמבר 2024

    Late Oxygenation of Marine Environments Revealed by Dolomite U-Pb Dating

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    שעה
    11:00 - 11:00
    מיקום
    בניין משפחת זוסמן
    מרצהUri Ryb
    Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    תקצירShow full text abstract about causal relationships between evolution and oxygenation of th...»
    causal relationships between evolution and oxygenation of the ocean are
    vigorously debated. At the heart of these uncertainties are inconsistencies
    among reconstructed timelines for the rise of O2 in marine habitats. Attempts to
    reconstruct the timing of marine oxygenation are often based on redox-sensitive
    geochemical proxies that are prone to post-depositional alteration. Thus,
    developing new proxies, more resistant to such alteration, is an important
    direction forward for constraining major changes in atmospheric and marine
    oxygen levels. Here, we utilize U–Pb dating in dolomite to reconstruct their
    (re)crystallization ages and initial 207Pb/206Pb ratios; we find that they are
    systematically younger and lower than expected, respectively. These
    observations are explained by the resetting of the U–Pb system long after
    deposition, followed by further evolution in a closed system. Initial 207Pb/206Pb
    ratios have decreased from expected terrestrial values in the interval between
    deposition and (re)crystallization, consistent with U decay, and can therefore be
    used to reconstruct the initial 238U/206Pb ratios during deposition. Within our
    dataset initial 238U/206Pb ratios remained low in Proterozoic to mid-Paleozoic
    samples and increased dramatically in samples from the late-Paleozoic–early-
    Mesozoic Eras. This rise is attributed to a higher ratio of U to Pb in seawater that
    in turn influenced the fluid composition of carbonate crystallization sites.
    Accordingly, we interpret the temporal shift in initial 238U/206Pb ratios to reflect
    a late-Paleozoic increase in oxygenation of marine environments, corroborating
    previously documented shifts in some redox-sensitive proxies. This timeline is
    consistent with evolution-driven mechanisms for the oxygenation of late
    Paleozoic marine environments and with suggestions that Neoproterozoic and
    early Paleozoic animals thrived in oceans that overall and on long time scales
    were oxygen-limited compared to the modern ocean.
    הרצאה
  • Date:10ראשוןנובמבר 2024

    The Clore Center for Biological Physics

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    שעה
    13:15 - 14:30
    כותרת
    Two-Part Seminar: Predicting antibiotic resistance & AI-driven science
    מיקום
    ספרית הפיסיקה על שם נלה וליאון בנוזיו
    מרצהProf. Roy Kishony
    Technion -Faculty of Biology, Department of Bioinformatics and Systems Biology
    מארגן
    מרכז לפיזיקה ביולוגית עש קלור
    צרו קשר
    תקצירShow full text abstract about In this two-part talk, I will try to cover two separate line...»
    In this two-part talk, I will try to cover two separate lines of research: Machine learning of antibiotic resistance and AI-driven Science. In the first half, I will describe our efforts to understand and predict antibiotic resistance at the single patient level. I will describe a series of experimental-computational methodologies for following and identifying recurrent patterns in the evolution of antibiotic resistance in the lab and in the clinic. Combined with machine-learning approaches applied to electronic patient records, these tools lead to predictive diagnostics of antibiotic resistance and algorithms for personalized treatments of microbial infections. In the second part of the talk, we will shift gear and talk about AI-driven science. I will describe and demo “data-to-paper”: a platform that autonomously guides LLMs (like ChatGPT) to perform entire research cycles. Provided with data alone, data-to-paper can raise hypotheses, design research plans, write and debug analysis codes, generate and interpret results, and write complete research papers. Automatic information-tracing through the process creates manuscripts in which results, methods and data are programmatically chained. Our work thereby demonstrates a potential for AI-driven acceleration of scientific discovery while enhancing, rather than jeopardizing, traceability, transparency and verifiability. I will describe the strengths of the approach as well as limitations and challenges.

    Prof. Kishony would be available to discuss with students and
    postdocs after his seminar (2:15 pm - 3 pm).
    So we encourage interested students and postdocs to stay after his talk!

    FOR THE LATEST UPDATES AND CONTENT ON SOFT MATTER AND BIOLOGICAL PHYSICS AT THE WEIZMANN, VISIT OUR WEBSITE: https://www.biosoftweizmann.com/
    הרצאה
  • Date:11שנינובמבר 2024

    Midrasha on Groups Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Reading Alan Turing
    מיקום
    בניין יעקב זיסקינד
    מרצהAvi Wigderson
    IAS Princeton
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about I will discuss some well-known and less-known papers of Turi...»
    I will discuss some well-known and less-known papers of Turing, exemplify the scope of deep, prescient ideas he put forth, and mention follow-up work on these by the Theoretical CS community.

    No special background will be assumed.
    הרצאה
  • Date:11שנינובמבר 2024

    Foundations of Computer Science Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Reading Alan Turing
    מיקום
    בניין יעקב זיסקינד
    מרצהAvi Wigderson
    IAS
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    צרו קשר
    תקצירShow full text abstract about I will discuss some well-known and less-known papers of Turi...»
    I will discuss some well-known and less-known papers of Turing, exemplify the scope of deep, prescient ideas he put forth, and mention follow-up work on these by the Theoretical CS community.

    No special background will be assumed.
    הרצאה
  • Date:11שנינובמבר 2024

    PhD thesis defense- Avia Mizrachi

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    שעה
    14:00 - 15:00
    כותרת
    Phenotypic variability and cell fate determination in marine diatoms in response to environmental stress
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו למדעי הצמח
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:11שנינובמבר 2024

    Midrasha on Groups Seminar

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    שעה
    14:15 - 16:00
    כותרת
    High-dimensional expansion and soficity of groups
    מיקום
    בניין יעקב זיסקינד
    מרצהAndreas Thom
    TU Dresden
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about For d≥4 and p a sufficiently large prime, we construct a lat...»
    For d≥4 and p a sufficiently large prime, we construct a lattice Γ≤PSp2d(ℚp), such that its universal central extension cannot be sofic if Γ satisfies some weak form of stability in permutations. In the proof, we make use of high-dimensional expansion phenomena and, extending results of Lubotzky, we construct new examples of cosystolic expanders over arbitrary finite abelian groups. This is joint with with Lukas Gohla.
    הרצאה
  • Date:12שלישינובמבר 2024

    Special Guest Seminar

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    שעה
    11:00 - 12:00
    כותרת
    EV-DNA Drives Anti-Tumor Immunity and Inhibits Metastasis
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהDr. Inbal Wortzel
    מארגן
    המחלקה לאימונולוגיה ורגנרציה ביולוגית
    צרו קשר
    הרצאה
  • Date:13רביעינובמבר 2024

    Piezo2 in sensory neurons controls systemic metabolism by inhibiting adipose thermogenesis

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    שעה
    10:00 - 11:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Eli Zelzer
    Department of Molecular Genetics
    צרו קשר
    הרצאה
  • Date:13רביעינובמבר 2024

    Machine Learning and Statistics Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Exact Phase Transitions for Sparse PCA in High Dimensions
    מיקום
    בניין יעקב זיסקינד
    מרצהMichael Feldman
    WIS
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    צרו קשר
    תקצירShow full text abstract about Sparse principal component analysis (PCA) is a powerful meth...»
    Sparse principal component analysis (PCA) is a powerful method for low-rank and sparse signal recovery, applicable to covariance estimation, dimension reduction, and feature selection. In this work, we study a generalization of the covariance-thresholding approach to sparse PCA, improving results of R. Krauthgamer, B. Nadler, D. Vilenchik (2015), and Y. Deshpande, A. Montanari (2016). Through random matrix theory, we identify novel phase transition phenomena in high dimensions, providing insight into the limits of signal and support recovery. Our results rely on new concentration bounds for quadratic forms of kernel matrices, which are of independent interest. This research is a collaboration with Theodor Misiakiewicz (Yale) and Elad Romanov (Stanford).

     
    הרצאה
  • Date:13רביעינובמבר 2024

    The Clore Center for Biological Physics

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    שעה
    13:15 - 14:30
    כותרת
    Enzymes as sequence-encoded, viscoelastic catalytic machines
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Tsvi Tlusty
    Center for Soft and Living Matter, Ulsan National Institute of Science and Technology.
    מארגן
    מרכז לפיזיקה ביולוגית עש קלור
    צרו קשר
    תקצירShow full text abstract about Protein function is the combined product of chemical and mec...»
    Protein function is the combined product of chemical and mechanical interactions encoded in the gene. Thus, the function of enzymes relies on finetuning the chemical groups at the active site, but also on large-scale mechanical motions, allowing enzymes to bind to substrates selectively, reach the transition state, and release products. We will discuss recent work aiming to probe directly the linkage between these collective internal motions and the functionality of enzymes, using nano-rheological measurements, AI-prediction of point mutation effects, and physical theory. This work proposes a physical view of enzymes as viscoelastic catalytic machines with sequence-encoded mechanical specifications, which are modulated via long-ranged force transduction.
    הרצאה
  • Date:14חמישינובמבר 2024

    PhD Thesis Defense - Hila Tishler (Prof. Ayelet Erez Lab)

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    שעה
    11:30 - 11:30
    כותרת
    Enhancing the Sensitivity of Triple Negative Breast Cancers to JAK-STAT Inhibitors by Targeting Arginine Availability
    מיקום
    בניין אולמן למדעי החיים
    מרצהDr. Hila Tishler
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:14חמישינובמבר 2024

    Revisiting the Neoantigen Approach to Cancer Immunotherapy

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    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהProf. Yardena Samuels
    Knell Family Professorial Chair Director, the EKARD Institute for Cancer Diagnosis Research President Elect, European Association for Cancer Research Department of Molecular Cell Biology The Weizmann Institute of Science
    מארגן
    מרכז הבינתחומי לחקר סרטן עש מורוס
    צרו קשר
    הרצאה
  • Date:14חמישינובמבר 2024

    An unconventional journey from, almost, obvious questions to new ideas in exocytosis

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    שעה
    15:00 - 16:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהProf. Ori Avinoam
    Dept. of Biomolecular Sciences-WIS
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    תקצירShow full text abstract about A wide range of vertebrate secretory glands, such as the exo...»
    A wide range of vertebrate secretory glands, such as the exocrine pancreas and lung goblet cells, package their cargoes in large vesicles (LSVs). The diameter of these vesicles ranges from 1 to 10 µm, roughly the size of a yeast cell. The membrane surface area and internal volume of these vesicles are orders of magnitude greater than those of conventional vesicles (30–500 nm in diameter), posing formidable challenges for vesicle biogenesis, trafficking, fusion, content release, and the maintenance of apical membrane homeostasis. By asking how cells compensate for the significant membrane load introduced by LSVs at the cell surface, our work uncovered an entirely overlooked mode of exocytosis and revealed key components of the intricate molecular mechanisms underlying LSV fusion and exocytosis in exocrine tissues.
    הרצאה

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