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אפריל 28, 2015
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Date:02שלישייוני 2015הרצאה
Recent advances in Imaging Flow Cytometry – The 3rd Israeli ImagestreamX user meeting
More information שעה 09:00 - 12:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימארגן המחלקה לתשתיות מחקר מדעי החייםצרו קשר תקציר Show full text abstract about Imaging Flow Cytometry combines speed, sensitivity, and phen...» Imaging Flow Cytometry combines speed, sensitivity, and phenotyping abilities found in flow cytometry with the detailed imagery and functional insight of microscopy, for an extensive range of novel applications. It allows quantitating cellular morphology and the intensity and location of fluorescent probes on, in, or between cells, even in rare sub-populations and highly heterogeneous samples. The wide range of applications used include studying intracellular localization, shape changes and morphology, co-localization, nuclear translocation, cell signaling, T cell – APC interactions, DNA damage and repair, cell death and apoptosis, phagocytosis and internalization, FISH, vesicle trafficking, and many others. -
Date:02שלישייוני 2015הרצאה
A fully functional Calvin cycle in a heterotrophic host : getting E.coli
More information שעה 11:15 - 11:15כותרת to join the Dept. of Plant and Environmental Sciencesמיקום בניין אולמן למדעי החייםמרצה Niv Antonovsky
Lab. of Prof. Ron Milo, Dept. of Plant and Environmental Sciencesמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:02שלישייוני 2015הרצאה
Goal-directed navigation with 3D neural compasses
More information שעה 12:30 - 12:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Arseny Finkelstein
Dept of Neurobiology, WISמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Although animals and humans move daily through complex three...» Although animals and humans move daily through complex three-dimensional (3D) environments, practically nothing is known about the encoding of 3D head direction in the brain. Moreover, very little is known about how neural circuits represent the location or direction of spatial goals – which is essential for goal-directed navigation.
In the first part of the talk, I will present the first neural recordings of 3D head-direction cells from the hippocampal formation of flying and crawling bats, and will describe the functional organization and the surprising properties of these neurons. By using the head-direction system as an example, I will also discuss several theoretical considerations for the existence of both pure and conjunctive population codes in the brain.
In the second part, I will present our new findings that suggest the existence of goal-direction and goal-proximity signals in the bat hippocampus – a vectorial representation that could support goal-directed navigation.
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Date:02שלישייוני 2015הרצאה
Crystal structure of phoshotransmitter AHP2 and modelling of its interaction with the receiver domain of sensor histidine kinase CKI1 – towards specificity in the multistep phosphorelay signaling in plants
More information שעה 14:00 - 15:00מיקום בניין הלן ומילטון קימלמןמרצה Dr. Oksana Degtjarik מארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:03רביעייוני 2015כנסים
RNA-Protein Macromolecular Assemblies at the Crossroads of Cellular Stress and Neurodegeneration
More information שעה כל היוםמיקום מרכז כנסים על-שם דויד לופאטייושב ראש Eran Hornsteinדף בית צרו קשר -
Date:03רביעייוני 2015הרצאה
Forum on Mathematical Principles in Biolog
More information שעה 10:00 - 11:00כותרת “Public T cell networks – the immune system’s selfie?”מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Nir Friedman מארגן המחלקה לביולוגיה מולקולרית של התאצרו קשר -
Date:03רביעייוני 2015הרצאה
From pH-gating to toxin inhibition: structure-function studies of the KcsA potassium channel
More information שעה 10:00 - 11:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Jordan Cill
Dept.of Chemistry Bar Ilan Univ.מארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about KcsA has been extensively studied as a paradigm of structure...» KcsA has been extensively studied as a paradigm of structure-function relations in potassium channels. Structure determination of KcsA and several other related channels has revealed many of the molecular features of these membrane-embedded proteins. In this seminar I hope to illuminate certain unexplored aspects of potassium channel behavior using biomolecular NMR. Membrane proteins are notoriously challenging for structural study due to the need to stabilize them in a membrane-mimicking detergent- or lipid-based environment. Thus, the first necessary breakthrough was establishing that NMR is capable of addressing this large molecular assembly estimated at 120-170 kDa depending on choice of detergent. This achievement has laid the foundation for further investigations of KcsA activity, of which I will present two, (i) an under-appreciated pH-dependent oligomerization domain, and (ii) toxin inhibition of channel conduction. Together these examples demonstrate the versatility of solution NMR in uncovering the molecular mechanisms behind biological function involving protein structure and flexibility.
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Date:03רביעייוני 2015הרצאה
Some Exact Results on Quenched Disorder
More information שעה 13:15 - 14:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Zohar Komargodski
Weizmann Instituteמארגן המחלקה לפיזיקה של חומר מעובהצרו קשר תקציר Show full text abstract about We investigate several questions that concern with disorder ...» We investigate several questions that concern with disorder using three main methods:
A. A controlled expansion in the heat capacity critical exponent.
B. Large N models.
C. AdS/CFT
In the talk I will probably not get to say much about method C., but I will explain methods A. and B.
Method A. can be used to derive concrete results about the disordered 3d Ising model. Method B. can be used to derive a certain generalization of the Imry-Ma result and also it leads to some predictions that can be cross-checked using method C. Using method B. one can also obtain closed form RG flows between pure and disordered fixed points.
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Date:03רביעייוני 2015הרצאה
Integration of Coagulation Signaling in Innate Immunity and Inflammation
More information שעה 14:00 - 15:00כותרת Special Guest Seminarמיקום בניין וולפסון למחקר ביולוגימרצה Wolfram Ruf, M.D.
Professor, Department of Immunology and Microbial Science The Scripps Research Institute La Jolla, CAמארגן המחלקה לאימונולוגיה מערכתיתצרו קשר -
Date:03רביעייוני 2015הרצאה
Theoretical Principles of Virus-Microbe Dynamics
More information שעה 14:15 - 14:15מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Prof Joshua Weitz
Georgia Institute of Technologyמארגן המחלקה לפיזיקה של מערכות מורכבותצרו קשר -
Date:04חמישייוני 2015הרצאה
Options Beyond Academia in Scientific Editing
More information שעה 09:00 - 09:00מיקום בניין וולפסון למחקר ביולוגימרצה Prof. Laura M. Zahn
Senior Editor of SCIENCEמארגן המחלקה לאימונולוגיה מערכתיתצרו קשר -
Date:04חמישייוני 2015סימפוזיונים
Dirac Electrons — Living on the Edge
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Pablo Jarillo-Herrero
MITמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about Over the past decade, the physics of low dimensional electro...» Over the past decade, the physics of low dimensional electronic systems has been revolutionized by the discovery of materials with very unusual electronic properties where the behavior of the electrons is governed by the Dirac equation. Among these, graphene has taken center stage due to its ultrarelativistic-like electron dynamics and its potential applications in nanotechnology. Moreover, recent advances in the design and nanofabrication of heterostructures based on van der Waals materials have enabled a new generation of quantum electronic transport experiments in graphene. In this talk I will describe our recent experiments exploring electron-electron interaction driven quantum phenomena in ultra-high quality graphene-based van der Waals heterostructures. In particular I will show two novel realizations of a symmetry-protected topological insulator state, specifically a quantum spin Hall state, characterized by an insulating bulk and conducting counterpropagating spin-polarized states at the system edges. Our experiments establish graphene-based heterostructures as highly tunable systems to study topological properties of condensed matter systems in the regime of strong e-e interactions and I will end my talk with an outlook of some of the exciting directions in the field. -
Date:04חמישייוני 2015הרצאה
Virology club 4th meeting
More information שעה 12:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Yossi Shaul
The evolution toolkit in viral genome miniaturizationצרו קשר -
Date:04חמישייוני 2015הרצאה
Explanations for inter-individual variations in the human immune response to tumors and pathogens
More information שעה 12:30 - 12:30מיקום בניין וולפסון למחקר ביולוגימרצה Dr. Nir Hacohen
Massachusetts General Hospital Ctr. for Immunology and Inflammatory Diseasesמארגן המחלקה לאימונולוגיה מערכתיתצרו קשר -
Date:07ראשוןיוני 201511חמישייוני 2015כנסים
ICSG2015 - Deep Sequencing Meets Structural Biology
More information שעה כל היוםמיקום מרכז כנסים על-שם דויד לופאטייושב ראש Joel Sussmanדף בית צרו קשר -
Date:07ראשוןיוני 2015הרצאה
From yeast mating to Hutchinson-Gilford Progeria Syndrome (HGPS), a premature aging disorder
More information שעה 10:00 - 10:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Prof. Susan Michaelis
Dept. of Cell Biology, John Hopkins School of Medicine, Baltimore, USAמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:07ראשוןיוני 2015הרצאה
TBA
More information שעה 11:00 - 11:00מיקום בניין משפחת זוסמןמרצה Debbie Lindell
The Faculty of Biology Technionמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר -
Date:07ראשוןיוני 2015הרצאה
Experimental Investiagation of radiative rayleigh-taylor instability In 1 A Ma Gas-Puff Z-Pinch
More information שעה 11:15 - 11:15מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה P. de Grouchy מארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהצרו קשר תקציר Show full text abstract about A gas-puff z-pinch begins with the injection of a column of ...» A gas-puff z-pinch begins with the injection of a column of gas between the electrodes of a pulsed-power driver using a fast valve. This gas is preionized and then cylindrically compressed by discharge of a high current through the column. Using Argon gas, these current-driven implosions are a well-developed, high-intensity source of ~3keV, radiation [1]. Optimization of gas-puff sources depends on manipulation of the radial mass-density and gas-species profiles injected by the puff valve, achieved using multiple concentric nozzles backed by independently pressurized gas plena [2]. In particular, the Rayleigh-Taylor unstable boundary between the lower density current sheath and higher density shell of entrained gas, must be carefully controlled. We present experimental results of the response of this instability to radiative losses during the implosion phase using both Argon (Ar) and Krypton (Kr) gas puffs. Experiments are performed using a 7cm outer diameter, triple-annular nozzle designed, developed and characterized at the Weizmann Institute and fielded on the 200 ns, 1 MA COBRA generator at Cornell University. Time-gated density measurements are recorded by 532 nm small-shift shearing interferometers, acceleration of the boundary by streaked and time-gated x-ray cameras, and plasma temperatures are inferred from 527 nm Thomson scattering across the implosion region. RT amplitude e-folding times of 20 ns are recorded in Kr, 20% faster than in Ar under otherwise identical conditions. Ion temperatures of 100 eV are recorded in Kr shells, ~40% lower than in Ar, and it appears this cooling is responsible for the observed increase in RT growth rate.
* This work was supported by students and staff of the COBRA facility at Cornell University, and sponsored by the NNSA Stewardship Sciences Academic Programs.
[1] B. Jones et al. IEEE Trans. Plasma Sci. 42 1145-1152 (2014)
[2] A. Velikovich et al. Phys. Rev. Lett. 77 853-856 (1996)
[3] C. Jennings et al. Phys. Plasmas accepted (2015)
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Date:07ראשוןיוני 2015הרצאה
Cell to cell transfer of mRNA
More information שעה 13:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Dr. Gal Haimovich
Jeffrey Gerst's group, Dept. of Molecular Genetics, WISצרו קשר -
Date:08שנייוני 2015סימפוזיונים
"Rydberg states of atoms and molecules"
More information שעה 11:00 - 12:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Frederic Merkt
Laboratory of Physical Chemistry, ETH Zurich, Switzerlandמארגן הפקולטה לכימיהצרו קשר תקציר Show full text abstract about Rydberg states are electronically excited states, the spectr...» Rydberg states are electronically excited states, the spectral position of which can be described by Rydberg’s well-known formula. The physical properties of these states become very unusual at high values of the principal quantum number n: Their polarizability scales as n7, the van der Waals interaction between two Rydberg atoms or molecules as n11, the maximal electric dipole that can be induced by an electric field as n2, the threshold field for field ionization as n-4, the spacing between adjacent states of a given Rydberg series as n-3, the absorption cross section from the ground state as n-3, the transition moment between neighboring Rydberg states as n2, their lifetime as n3, etc. These physical properties and their rapid variation with n form the basis of a growing number of applications of Rydberg states in chemistry and physics.
The talk will begin with an overview of the properties of Rydberg states and their applications in physics and chemistry. I shall then present specific applications of Rydberg states my group is interested in. In the first, we use Rydberg states to carry out precision measurements of dissociation and ionization energies of molecules to test quantum electrodynamics calculations in small molecular systems such as H2 and He2. In the second, we exploit the large dipole moments of Rydberg states to control the translational motion of atoms and molecules, and develop methods to accelerate, focus, deviate and reflect beams of cold atoms and molecules, the latest experiments being carried out near the surface of chips. In the third, we study ion-molecule reactions at low temperatures within the Rydberg-electron orbit.
