Bioinformatics: LSCF Publications

  1. Vardi A., Pri-Or A., Wigoda N., Grishchuk Y. & Futerman A. H. (2021). Proteomics analysis of a human brain sample from a mucolipidosis type IV patient reveals pathophysiological pathways.  Orphanet Journal of Rare Diseases. 2021 Jan 21 , 16 (1).
  2. Zaidman D., Prilusky J., Cohen G., Resnick E., Barr H. & London N. (2021). An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor.  Cell Chemical Biology. 2021 Dec 16 , 28 (12):1795-1806.e5.
  3. Castro C., Johnson R. J., Kieffer B., Means J. A., Taylor A., Telford J., Thompson L. K., Sussman J. L., Prilusky J. & Theis K. (2021). A practical guide to teaching with Proteopedia.  Biochemistry and Molecular Biology Education. 2021 Sept 1 , 49 (5):707-719.
  4. Dekel E., Yaffe D., Rosenhek-Goldian I., Ben-Nissan G., Ofir-Birin Y., Morandi M. I., Ziv T., Sisquella X., Pimentel M. A., Nebl T., Kapp E., Ohana Daniel Y., Karam P. A., Alfandari D., Rotkopf R., Malihi S., Temin T. B., Mullick D., Revach O. Y., Rudik A., Gov N. S., Azuri I., Porat Z., Bergamaschi G., Sorkin R., Wuite G. J., Avinoam O., Carvalho T. G., Cohen S. R., Sharon M. & Regev-Rudzki N. (2021). 20S proteasomes secreted by the malaria parasite promote its growth.  Nature Communications. 2021 Dec 1 , 12 (1).
  5. Dekel E., Yaffe D., Rosenhek-Goldian I., Ben-Nissan G., Ofir-Birin Y., Morandi M. I., Ziv T., Sisquella X., Pimentel M. A., Nebl T., Kapp E., Ohana Daniel Y., Karam P. A., Alfandari D., Rotkopf R., Malihi S., Temin T. B., Mullick D., Revach O. Y., Rudik A., Gov N. S., Azuri I., Porat Z., Bergamaschi G., Sorkin R., Wuite G. J., Avinoam O., Carvalho T. G., Cohen S. R., Sharon M. & Regev-Rudzki N. (2021). 20S proteasomes secreted by the malaria parasite promote its growth.  Nature Communications. 2021 Dec 1 , 12 (1).
  6. Heinemann-Yerushalmi L., Bentovim L., Felsenthal N., Vinestock R. C., Michaeli N., Krief S., Silberman A., Cohen M., Ben-Dor S., Brenner O., Haffner-Krausz R., Itkin M., Malitsky S., Erez A. & Zelzer E. (2021). BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development.  Developmental Cell. 2021 Apr 19 , 56 (8):1182-1194.e6.
  7. Kult S., Olender T., Osterwalder M., Markman S., Leshkowitz D., Krief S., Blecher-Gonen R., Ben-Moshe S., Farack L., Keren-Shaul H., Salame T. M., Capellini T. D., Itzkovitz S., Amit I., Visel A. & Zelzer E. (2021). Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors.  eLife. 2021 Jan 15 , 10 :1-29.
  8. Benjamin A., Kuperman Y., Eren N., Rotkopf R., Amitai M., Rossman H., Shilo S., Meir T., Keshet A., Nuttman-Shwartz O., Segal E. & Chen A. (2021). Stress-related emotional and behavioural impact following the first COVID-19 outbreak peak.  Molecular Psychiatry. 2021 Nov , 26 (11):6149-6158.
  9. Tsamir-Rimon M., Ben-Dor S., Feldmesser E., Oppenhimer-Shaanan Y., David-Schwartz R., Samach A. & Klein T. (2021). Rapid starch degradation in the wood of olive trees under heat and drought is permitted by three stress-specific beta amylases.  New Phytologist. 2021 Feb , 229 (3):1398-1414.
  10. Soll M., Goldshtein H., Rotkopf R., Russek-Blum N. & Gross Z. (2021). A synthetic sod/catalase mimic compound for the treatment of als.  Antioxidants. 2021 Jun , 10 (6).
  11. Grunwald Y., Wigoda N., Sade N., Yaaran A., Torne T., Gosa S. C., Moran N. & Moshelion M. (2021). Arabidopsis leaf hydraulic conductance is regulated by xylem sap pH, controlled, in turn, by a P-type H+-ATPase of vascular bundle sheath cells.  The Plant journal : for cell and molecular biology. 2021 Apr , 106 (2):301-313.
  12. Pewzner-Jung Y., Joseph T., Blumenreich S., Vardi A., Ferreira N. S., Cho S. M., Eilam R., Tsoory M., Biton I. E., Brumfeld V., Haffner-Krausz R., Brenner O., Sharabi N., Addadi Y., Salame T. M., Rotkopf R., Wigoda N., Yayon N., Merrill A. H., Schiffmann R. & Futerman A. H. (2021). Brain pathology and cerebellar purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease.  Progress in Neurobiology. 2021 Feb , 197 .
  13. Pewzner-Jung Y., Joseph T., Blumenreich S., Vardi A., Ferreira N. S., Cho S. M., Eilam R., Tsoory M., Biton I. E., Brumfeld V., Haffner-Krausz R., Brenner O., Sharabi N., Addadi Y., Salame T. M., Rotkopf R., Wigoda N., Yayon N., Merrill A. H., Schiffmann R. & Futerman A. H. (2021). Brain pathology and cerebellar purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease.  Progress in Neurobiology. 2021 Feb , 197 .
  14. Graff van Creveld S., Ben-Dor S., Mizrachi A., Alcolombri U., Hopes A., Mock T., Rosenwasser S. & Vardi A. (2021). Biochemical Characterization of a Novel Redox-Regulated Metacaspase in a Marine Diatom.  Frontiers in Microbiology. 2021 Sept 8 , 12 .
  15. Camargo S., Leshkowitz D., Dassa B., Mariscal V., Flores E., Stavans J. & Arbel-Goren R. (2021). Impaired cell-cell communication in the multicellular cyanobacterium Anabaena affects carbon uptake, photosynthesis, and the cell wall.  iScience. 2021 Jan 22 , 24 (1).
  16. Mevorach T., Taler M., Dar S., Lebow M., Sapir I. S., Rotkopf R., Apter A., Fennig S., Chen A., Weizman A. & Amitai M. (2021). The relationship between the plasma proinflammatory cytokine levels of depressed/anxious children and their parents.  Scientific Reports. 2021 Dec , 11 (1).
  17. Maddalena M., Mallel G., Nataraj N. B., Shreberk-Shaked M., Hassin O., Mukherjee S., Arandkar S., Rotkopf R., Kapsack A., Lambiase G., Pellegrino B., Ben-Isaac E., Golani O., Addadi Y., Hajaj E., Eilam R., Straussman R., Yarden Y., Lotem M. & Oren M. (2021). TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.  Proceedings of the National Academy of Sciences. 2021 Jun 4 , 118 (23).
  18. Camargo S., Leshkowitz D., Dassa B., Mariscal V., Flores E., Stavans J. & Arbel-Goren R. (2021). Impaired cell-cell communication in the multicellular cyanobacterium Anabaena affects carbon uptake, photosynthesis, and the cell wall.  iScience. 2021 Jan 22 , 24 (1).
  19. Doron E., Koppel I., Abraham O., Rishal I., Smith T. P., Buchanan C. N., Sahoo P. K., Kadlec J., Oses-Prieto J. A., Kawaguchi R., Alber S., Zahavi E. E., Di Matteo P., Di Pizio A., Song D. A., Okladnikova N., Gordon D., Ben-Dor S., Haffner-Krausz R., Coppola G., Burlingame A. L., Jungwirth P., Twiss J. L. & Fainzilber M. (2021). The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization.  EMBO Journal. 2021 Oct 18 , 40 (20).
  20. Kazachkova Y., Zemach I., Panda S., Bocobza S., Vainer A., Rogachev I., Dong Y., Ben-Dor S., Veres D., Kanstrup C., Lambertz S. K., Crocoll C., Hu Y., Shani E., Michaeli S., Nour-Eldin H. H., Zamir D. & Aharoni A. (2021). The GORKY glycoalkaloid transporter is indispensable for preventing tomato bitterness.  Nature Plants. 2021 Apr , 7 (4):468-480.