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ינואר 01, 2015
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Date:06שלישייולי 2021הרצאה
Halite deposition in the Dead Sea: Direct observations and lessons for thick halite sequences in the geological record
More information שעה 10:00 - 11:00מיקום https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09מרצה Ido Sirota
Institute of Earth Sciences The Hebrew University of Jerusalemמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about Layered halite sequences were deposited in deep hypersaline ...» Layered halite sequences were deposited in deep hypersaline basins throughout the geological record. These sequences are of research interest for hydrocarbon extraction, mineral exploration, tectonics and structural geology and paleoclimate research. Modern analogs and the processes leading to deposition of thick halite sequences were studied only through analyses of the common modern, shallow environments, which are fundamentally different in their nature from halite-depositing, deep waterbodies. Thus, the spatiotemporal evolution of halite sequences remained ambiguous. I will present, first, a study of the active precipitation of halite layers from the only modern analog in the world for deep, halite-precipitating basin; the hypersaline Dead Sea. Then the implications of these results to the geological record will be emphasized. Novel in situ observations in the Dead Sea link seasonal hydroclimatic conditions, thermohaline stratification, halite saturation, and the characteristics of the actively forming halite layers. The main findings of this study are: (a) Halite deposition dynamics is directly related to the development of the thermohaline stratification and it is primarily temperature controlled; it is counter-intuitive to the common approach that focus on the role of the hydrological budget in the study of hypersaline environments. (b) A pronounced depth dependency of the degree of halite saturation and halite deposition. (c) A well-defined seasonality of halite deposition on the deep lakefloor. (d) Preferential halite accumulation at the deep, hypolimnetic lake floor (>25m depth) due to intensive halite dissolution at the shallow epilimnetic lakefloor, and its re-deposition at depth, in a process termed “halite focusing”. (e) Halite accumulates at high rates in the deep lakefloor, doubling (or even more) the expected thickness without halite focusing. (f) Freshwater inflows further amplify halite thickness at the drier parts of the lake. These findings provide insights and quantify the processes required for reconstructing past hypersaline environments from halite sequences, in the Dead Sea and worldwide. -
Date:06שלישייולי 2021הרצאה
Intermolecular Interactions: Surfaces, Molecules and Molecular Solids
More information שעה 11:00 - 12:00כותרת HYBRID departmental seminarמיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Dr. A. Daniel Boese
University of Graz, Graz, Austriaמארגן המחלקה לכימיה מולקולרית ולמדע חומריםצרו קשר -
Date:06שלישייולי 2021הרצאה
Conservation of TIR immune signaling in bacteria and plants
More information שעה 11:30 - 12:30כותרת Guest Seminar via Zoomמיקום https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190מרצה Gal Ofir
Prof. Rotem Sorek's Lab., Department of Molecular Genetics, WISמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:07רביעייולי 2021הרצאה
SAERI - Sustainability and Energy Research Initiative seminar series
More information שעה 13:00 - 14:00מיקום via zoomמרצה Prof. Alice Larkin
Head of the School of Engineering and a researcher in the Tyndall Centre for Climate Change Research, University of Manchester, UKמארגן בית הספר למחקר - מכון ויצמן למדעצרו קשר -
Date:08חמישייולי 2021הרצאה
Love the neighbor – Unraveling the tumor microenvironment using multiplexed imaging
More information שעה 14:00 - 15:00מיקום בניין ע"ש מקס ולילאן קנדיוטימרצה Dr. Leeat Keren
Department of Molecular Cell Biology, Weizmann Institute of Scienceמארגן המכון לחקר הטיפול בסרטן עש דואקצרו קשר -
Date:12שנייולי 2021הרצאה
Special Guest Seminar
More information שעה 11:00 - 12:00כותרת The ribosome supracomplex: a new therapeutic target in viral infection and neurodegenerationמיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Dr. Ranen Aviner
Stanford Universityמארגן המחלקה למדעים ביומולקולרייםצרו קשר -
Date:12שנייולי 2021הרצאה
Special Guest Seminar
More information שעה 15:00 - 16:30כותרת Beyond Darwin: understanding cancer persister cellsמרצה Dr. Yaara Oren צרו קשר -
Date:19שנייולי 2021סימפוזיונים
Developing first-principles methods to study force- and stress-enabled mechanochemistry
More information שעה 11:00 - 12:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Andrew M. Rappe
University of Pennsylvaniaמארגן הפקולטה לכימיהצרו קשר תקציר Show full text abstract about A wide variety of chemical transformations can be induced by...» A wide variety of chemical transformations can be induced by the application of force or stress to reactive systems. In some cases, these reactions are undesired, including some tribochemical (friction-induced) reactions and bond-breaking in polymers under stress. A large and growing set of examples shows that mechanochemistry can be harnessed for useful chemical transformations, making the case for mechanochemistry as a general-purpose tool to advance chemical innovation. In order to realize this vision, we require greater understanding of how force and stress can be focused on particular bonds and reaction coordinates, and how this enhances chemical reactivity and selectivity. In this talk, I will outline strategies for applying stress to quantum-mechanical models of reactive chemical systems and for understanding the resulting mechanochemical reaction pathways. I will also describe the development of interatomic potential models that can enable larger-scale models of mechanochemical and piezoelectric effects in molecules, 2D materials, and polar solids. -
Date:20שלישייולי 2021הרצאה
Defense metabolites: from eco systems to growth
More information שעה 10:00 - 11:00כותרת Guest Seminar via Zoomמיקום https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190מרצה Ella Katz
Lab of Prof. Dan Kliebenstein, Department of Plant Sciences, UC Davis, USAמארגן המחלקה למדעי הצמח והסביבהצרו קשר -
Date:20שלישייולי 2021הרצאה
Special guest seminar with Dr. Inna Ricardo-Lax
More information שעה 12:00 - 13:00כותרת Efficient replication and single cycle delivery of SARS-CoV2 repliconsמיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Dr. Inna Ricardo-Lax מארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:22חמישייולי 2021הרצאה
Imm Guest Seminar: Dr. Yael David will lecture on " Uncovering Cancer-Associated Epigenetic Events Using Novel Chemical Tools."
More information שעה 11:00 - 12:00מיקום בניין וולפסון למחקר ביולוגימרצה Dr. Yael David
Assistant Member Chemical Biology Program Memorial Sloan Kettering Cancer Center New York, NYמארגן המחלקה לאימונולוגיה מערכתיתצרו קשר -
Date:23שישייולי 2021אירועי תרבות
החברים של נתן
More information שעה 20:00 - 22:45כותרת מסיבת קיץ ישראליתמיקום אודיטוריום מיכאל סלעצרו קשר -
Date:25ראשוןיולי 2021הרצאה
A few lessons that nanoparticles can teach us about non-equilibrium properties of crystallization
More information שעה 10:00 - 11:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Dr. Assaf Ben Moshe, Ana Naamat
Dept Molecular Chemistry and Materials Science, WISמארגן המחלקה לכימיה מולקולרית ולמדע חומריםצרו קשר תקציר Show full text abstract about The fact that many crystals are not in equilibrium is quite ...» The fact that many crystals are not in equilibrium is quite obvious and not very surprising. Yet, this often complicates our attempts to understand some of their most fundamental properties, such as for instance, their overall morphology. To further add to this complexity, non-equilibrium properties are nowadays studied in crystals made out of building blocks that consume energy and actively propel (i.e., active matter).
Despite some complications that exist when trying to make analogies between the behavior of bulk crystals and their nanoscale analogs, the latter offer many advantages when studying kinetic aspects of crystal formation, in both “conventional” as well as “active” crystals. In my talk I will present two different cases where nanocrystals are used in order to shed light on some of these aspects. The first story dates all the way back to the 19th century and the seminal work by Louis Pasteur on crystals that exhibit chiral macroscopic shapes when made out of chiral building blocks. Using a model system of tellurium nanocrystals, I was able to show that the reason for chiral shape formation in crystals composed of chiral building blocks might not always be as trivial as expected. In the second part of the talk, I will present the first steps I took on an ongoing journey to understand the diffusion of extremely small (sub 10 nm) chemically propelled nanocrystals. This is meant to pave the way to ultimately use them as building blocks for non-equilibrium active crystalline matter.
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Date:26שנייולי 2021הרצאה
Our Changing Atmosphere: Carbon, Consequences, and Capture
More information שעה 18:00 - 19:00כותרת SAERI - Sustainability and Energy Research Initiative seminar seriesמיקום via zoomמרצה Prof. Jeffrey A. Reimer
Department of Chemical and Biomolecular Engineering University of California Berkeley, California, USAמארגן בית הספר למחקר - מכון ויצמן למדעצרו קשר -
Date:27שלישייולי 2021הרצאה
"IDP-membrane interactions in neurodegeneration and neuronal function”
More information שעה 14:00 - 15:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. David Eliezer
Weill Cornell Medicine Graduate School of Medical Sciences, NY, USAמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:04רביעיאוגוסט 2021הרצאה
Principles of functional circuit connectivity: Insights from the zebrafish optic tectum
More information שעה 10:30 - 10:30מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. German Sumbre
École Normale Supérieure, Franceמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Spontaneous neuronal activity in sensory brain regions is sp...» Spontaneous neuronal activity in sensory brain regions is spatiotemporally structured, suggesting that this ongoing activity may have a functional role. Nevertheless, the neuronal interactions underlying these spontaneous activity patterns, and their biological relevance, remain elusive. We addressed these questions using two-photon and light-sheet Ca2+ imaging of intact zebrafish larvae to monitor the fine structure of the spontaneous activity in the zebrafish optic tectum (the fish's main visual center. We observed that the spontaneous activity was organized in topographically compact assemblies, grouping functionally similar neurons rather than merely neighboring ones, reflecting the tectal retinotopic map. Assemblies represent all-or-none-like sub-networks shaped by competitive dynamics, mechanisms advantageous for visual detection in noisy natural environments. Furthermore, the spontaneous activity structure also emerged in “naive” tecta (tecta of enucleated larvae before the retina connected to the tectum). We thus suggest that the formation of the tectal network circuitry is genetically prone for its functional role. This capability is an advantageous developmental strategy for the prompt execution of vital behaviors, such as escaping predators or catching prey, without requiring prior visual experience.
Mutant zebrafish larvae for the mecp2 gene display an abnormal spontaneous tectal activity, thus representing an ideal control to shed light on the biological relevance of the tectal functional connectivity. We found that the tectal assemblies limit the span of the visual responses, probably improving visual spatial resolution.
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Date:05חמישיאוגוסט 2021הרצאה
A tale of four tales and more
More information שעה 14:00 - 15:00מרצה Prof. Eytan Ruppin
Chief, Cancer Data Science Lab, NCI, NIHמארגן המכון לחקר הטיפול בסרטן עש דואקצרו קשר -
Date:16שניאוגוסט 2021הרצאה
Special seminar with Dr. Yaara Oren
More information שעה 15:00 - 16:00כותרת Beyond Darwin: understanding cancer persister cellsמרצה Dr. Yaara Oren
The Broad Institute and Harvard Medical Schoolמארגן המחלקה לגנטיקה מולקולריתצרו קשר תקציר Show full text abstract about Despite favorable initial response to therapy, a third of ca...» Despite favorable initial response to therapy, a third of cancer patients will develop recurrent disease and succumb to it within five years of diagnosis. While there has been much progress in characterizing the pathways that contribute to stable genetic drug resistance, the mechanisms underlying early reversible resistance, also known as persisters-driven resistance, remain largely unknown. It has long been believed that persisters represent a subset of cells that happen to be non-proliferating at the time of treatment, and therefore can survive drugs that preferentially kill rapidly proliferating cells. However, in my talk I will describe a rare persister population which, despite not harboring any resistance-conferring mutation, can maintain proliferative capacity in the presence of drug. To study this rare, transiently-resistant, cycling persister population, we developed Watermelon, a high-complexity expressed barcode lentiviral library for simultaneous tracing of each cell’s clonal origin and proliferative and transcriptional states. We combine single cell transcriptomics with imaging and metabolomics to show that cycling and non-cycling persisters arise from different cell lineages with distinct transcriptional and metabolic programs. Finally, I will describe how by studying persister cells we can gain critical insights on cellular memory, fate, and evolution, which can guide the development of better anti-cancer treatments. -
Date:02חמישיספטמבר 2021כנסים
The Israeli Society for Developmental Biology %u2013IsSDB meeting ECM, cytoskeleton and migration
More information שעה 08:00 - 08:00יושב ראש Oren Schuldiner -
Date:12ראשוןספטמבר 2021אירועים אקדמיים
Scientific Council meeting
More information שעה 14:00 - 16:00מיקום מרכז כנסים על-שם דויד לופאטיצרו קשר
