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ינואר 01, 2015

  • Date:06שלישייולי 2021

    Halite deposition in the Dead Sea: Direct observations and lessons for thick halite sequences in the geological record

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    שעה
    10:00 - 11:00
    מיקום
    https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09
    מרצהIdo Sirota
    Institute of Earth Sciences The Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    תקצירShow full text abstract about Layered halite sequences were deposited in deep hypersaline ...»
    Layered halite sequences were deposited in deep hypersaline basins throughout the geological record. These sequences are of research interest for hydrocarbon extraction, mineral exploration, tectonics and structural geology and paleoclimate research. Modern analogs and the processes leading to deposition of thick halite sequences were studied only through analyses of the common modern, shallow environments, which are fundamentally different in their nature from halite-depositing, deep waterbodies. Thus, the spatiotemporal evolution of halite sequences remained ambiguous. I will present, first, a study of the active precipitation of halite layers from the only modern analog in the world for deep, halite-precipitating basin; the hypersaline Dead Sea. Then the implications of these results to the geological record will be emphasized. Novel in situ observations in the Dead Sea link seasonal hydroclimatic conditions, thermohaline stratification, halite saturation, and the characteristics of the actively forming halite layers. The main findings of this study are: (a) Halite deposition dynamics is directly related to the development of the thermohaline stratification and it is primarily temperature controlled; it is counter-intuitive to the common approach that focus on the role of the hydrological budget in the study of hypersaline environments. (b) A pronounced depth dependency of the degree of halite saturation and halite deposition. (c) A well-defined seasonality of halite deposition on the deep lakefloor. (d) Preferential halite accumulation at the deep, hypolimnetic lake floor (>25m depth) due to intensive halite dissolution at the shallow epilimnetic lakefloor, and its re-deposition at depth, in a process termed “halite focusing”. (e) Halite accumulates at high rates in the deep lakefloor, doubling (or even more) the expected thickness without halite focusing. (f) Freshwater inflows further amplify halite thickness at the drier parts of the lake. These findings provide insights and quantify the processes required for reconstructing past hypersaline environments from halite sequences, in the Dead Sea and worldwide.
    הרצאה
  • Date:06שלישייולי 2021

    Intermolecular Interactions: Surfaces, Molecules and Molecular Solids

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    שעה
    11:00 - 12:00
    כותרת
    HYBRID departmental seminar
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Dr. A. Daniel Boese
    University of Graz, Graz, Austria
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    צרו קשר
    הרצאה
  • Date:06שלישייולי 2021

    Conservation of TIR immune signaling in bacteria and plants

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    שעה
    11:30 - 12:30
    כותרת
    Guest Seminar via Zoom
    מיקום
    https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190
    מרצהGal Ofir
    Prof. Rotem Sorek's Lab., Department of Molecular Genetics, WIS
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:07רביעייולי 2021

    SAERI - Sustainability and Energy Research Initiative seminar series

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    שעה
    13:00 - 14:00
    מיקום
    via zoom
    מרצהProf. Alice Larkin
    Head of the School of Engineering and a researcher in the Tyndall Centre for Climate Change Research, University of Manchester, UK
    מארגן
    בית הספר למחקר - מכון ויצמן למדע
    צרו קשר
    הרצאה
  • Date:08חמישייולי 2021

    Love the neighbor – Unraveling the tumor microenvironment using multiplexed imaging

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    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהDr. Leeat Keren
    Department of Molecular Cell Biology, Weizmann Institute of Science
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    צרו קשר
    הרצאה
  • Date:12שנייולי 2021

    Special Guest Seminar

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    שעה
    11:00 - 12:00
    כותרת
    The ribosome supracomplex: a new therapeutic target in viral infection and neurodegeneration
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהDr. Ranen Aviner
    Stanford University
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    הרצאה
  • Date:12שנייולי 2021

    Special Guest Seminar

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    שעה
    15:00 - 16:30
    כותרת
    Beyond Darwin: understanding cancer persister cells
    מרצהDr. Yaara Oren
    צרו קשר
    הרצאה
  • Date:19שנייולי 2021

    Developing first-principles methods to study force- and stress-enabled mechanochemistry

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    שעה
    11:00 - 12:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Andrew M. Rappe
    University of Pennsylvania
    מארגן
    הפקולטה לכימיה
    צרו קשר
    תקצירShow full text abstract about A wide variety of chemical transformations can be induced by...»
    A wide variety of chemical transformations can be induced by the application of force or stress to reactive systems. In some cases, these reactions are undesired, including some tribochemical (friction-induced) reactions and bond-breaking in polymers under stress. A large and growing set of examples shows that mechanochemistry can be harnessed for useful chemical transformations, making the case for mechanochemistry as a general-purpose tool to advance chemical innovation. In order to realize this vision, we require greater understanding of how force and stress can be focused on particular bonds and reaction coordinates, and how this enhances chemical reactivity and selectivity. In this talk, I will outline strategies for applying stress to quantum-mechanical models of reactive chemical systems and for understanding the resulting mechanochemical reaction pathways. I will also describe the development of interatomic potential models that can enable larger-scale models of mechanochemical and piezoelectric effects in molecules, 2D materials, and polar solids.
    סימפוזיונים
  • Date:20שלישייולי 2021

    Defense metabolites: from eco systems to growth

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    שעה
    10:00 - 11:00
    כותרת
    Guest Seminar via Zoom
    מיקום
    https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190
    מרצהElla Katz
    Lab of Prof. Dan Kliebenstein, Department of Plant Sciences, UC Davis, USA
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:20שלישייולי 2021

    Special guest seminar with Dr. Inna Ricardo-Lax

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    שעה
    12:00 - 13:00
    כותרת
    Efficient replication and single cycle delivery of SARS-CoV2 replicons
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהDr. Inna Ricardo-Lax
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:22חמישייולי 2021

    Imm Guest Seminar: Dr. Yael David will lecture on " Uncovering Cancer-Associated Epigenetic Events Using Novel Chemical Tools."

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    שעה
    11:00 - 12:00
    מיקום
    בניין וולפסון למחקר ביולוגי
    מרצהDr. Yael David
    Assistant Member Chemical Biology Program Memorial Sloan Kettering Cancer Center New York, NY
    מארגן
    המחלקה לאימונולוגיה מערכתית
    צרו קשר
    הרצאה
  • Date:23שישייולי 2021

    החברים של נתן

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    שעה
    20:00 - 22:45
    כותרת
    מסיבת קיץ ישראלית
    מיקום
    אודיטוריום מיכאל סלע
    צרו קשר
    אירועי תרבות
  • Date:25ראשוןיולי 2021

    A few lessons that nanoparticles can teach us about non-equilibrium properties of crystallization

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    שעה
    10:00 - 11:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהDr. Assaf Ben Moshe, Ana Naamat
    Dept Molecular Chemistry and Materials Science, WIS
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    צרו קשר
    תקצירShow full text abstract about The fact that many crystals are not in equilibrium is quite ...»
    The fact that many crystals are not in equilibrium is quite obvious and not very surprising. Yet, this often complicates our attempts to understand some of their most fundamental properties, such as for instance, their overall morphology. To further add to this complexity, non-equilibrium properties are nowadays studied in crystals made out of building blocks that consume energy and actively propel (i.e., active matter).
    Despite some complications that exist when trying to make analogies between the behavior of bulk crystals and their nanoscale analogs, the latter offer many advantages when studying kinetic aspects of crystal formation, in both “conventional” as well as “active” crystals. In my talk I will present two different cases where nanocrystals are used in order to shed light on some of these aspects. The first story dates all the way back to the 19th century and the seminal work by Louis Pasteur on crystals that exhibit chiral macroscopic shapes when made out of chiral building blocks. Using a model system of tellurium nanocrystals, I was able to show that the reason for chiral shape formation in crystals composed of chiral building blocks might not always be as trivial as expected. In the second part of the talk, I will present the first steps I took on an ongoing journey to understand the diffusion of extremely small (sub 10 nm) chemically propelled nanocrystals. This is meant to pave the way to ultimately use them as building blocks for non-equilibrium active crystalline matter.
    הרצאה
  • Date:26שנייולי 2021

    Our Changing Atmosphere: Carbon, Consequences, and Capture

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    שעה
    18:00 - 19:00
    כותרת
    SAERI - Sustainability and Energy Research Initiative seminar series
    מיקום
    via zoom
    מרצהProf. Jeffrey A. Reimer
    Department of Chemical and Biomolecular Engineering University of California Berkeley, California, USA
    מארגן
    בית הספר למחקר - מכון ויצמן למדע
    צרו קשר
    הרצאה
  • Date:27שלישייולי 2021

    "IDP-membrane interactions in neurodegeneration and neuronal function”

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    שעה
    14:00 - 15:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. David Eliezer
    Weill Cornell Medicine Graduate School of Medical Sciences, NY, USA
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    צרו קשר
    הרצאה
  • Date:04רביעיאוגוסט 2021

    Principles of functional circuit connectivity: Insights from the zebrafish optic tectum

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    שעה
    10:30 - 10:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. German Sumbre
    École Normale Supérieure, France
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about Spontaneous neuronal activity in sensory brain regions is sp...»
    Spontaneous neuronal activity in sensory brain regions is spatiotemporally structured, suggesting that this ongoing activity may have a functional role. Nevertheless, the neuronal interactions underlying these spontaneous activity patterns, and their biological relevance, remain elusive. We addressed these questions using two-photon and light-sheet Ca2+ imaging of intact zebrafish larvae to monitor the fine structure of the spontaneous activity in the zebrafish optic tectum (the fish's main visual center. We observed that the spontaneous activity was organized in topographically compact assemblies, grouping functionally similar neurons rather than merely neighboring ones, reflecting the tectal retinotopic map. Assemblies represent all-or-none-like sub-networks shaped by competitive dynamics, mechanisms advantageous for visual detection in noisy natural environments. Furthermore, the spontaneous activity structure also emerged in “naive” tecta (tecta of enucleated larvae before the retina connected to the tectum). We thus suggest that the formation of the tectal network circuitry is genetically prone for its functional role. This capability is an advantageous developmental strategy for the prompt execution of vital behaviors, such as escaping predators or catching prey, without requiring prior visual experience.
    Mutant zebrafish larvae for the mecp2 gene display an abnormal spontaneous tectal activity, thus representing an ideal control to shed light on the biological relevance of the tectal functional connectivity. We found that the tectal assemblies limit the span of the visual responses, probably improving visual spatial resolution.
    הרצאה
  • Date:05חמישיאוגוסט 2021

    A tale of four tales and more

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    שעה
    14:00 - 15:00
    מרצהProf. Eytan Ruppin
    Chief, Cancer Data Science Lab, NCI, NIH
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    צרו קשר
    הרצאה
  • Date:16שניאוגוסט 2021

    Special seminar with Dr. Yaara Oren

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    שעה
    15:00 - 16:00
    כותרת
    Beyond Darwin: understanding cancer persister cells
    מרצהDr. Yaara Oren
    The Broad Institute and Harvard Medical School
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    תקצירShow full text abstract about Despite favorable initial response to therapy, a third of ca...»
    Despite favorable initial response to therapy, a third of cancer patients will develop recurrent disease and succumb to it within five years of diagnosis. While there has been much progress in characterizing the pathways that contribute to stable genetic drug resistance, the mechanisms underlying early reversible resistance, also known as persisters-driven resistance, remain largely unknown. It has long been believed that persisters represent a subset of cells that happen to be non-proliferating at the time of treatment, and therefore can survive drugs that preferentially kill rapidly proliferating cells. However, in my talk I will describe a rare persister population which, despite not harboring any resistance-conferring mutation, can maintain proliferative capacity in the presence of drug. To study this rare, transiently-resistant, cycling persister population, we developed Watermelon, a high-complexity expressed barcode lentiviral library for simultaneous tracing of each cell’s clonal origin and proliferative and transcriptional states. We combine single cell transcriptomics with imaging and metabolomics to show that cycling and non-cycling persisters arise from different cell lineages with distinct transcriptional and metabolic programs. Finally, I will describe how by studying persister cells we can gain critical insights on cellular memory, fate, and evolution, which can guide the development of better anti-cancer treatments.
    הרצאה
  • Date:02חמישיספטמבר 2021

    The Israeli Society for Developmental Biology %u2013IsSDB meeting ECM, cytoskeleton and migration

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    שעה
    08:00 - 08:00
    יושב ראש
    Oren Schuldiner
    כנסים
  • Date:12ראשוןספטמבר 2021

    Scientific Council meeting

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    שעה
    14:00 - 16:00
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    צרו קשר
    אירועים אקדמיים

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