MICC Cell Observatory Publications

  1. Mardamshina M., Karagach S., Mohan V., Arad G., Necula D., Golani O., Fellus-Alyagor L., Shenoy A., Krol K., Pirak D., Itzhacky N., Marin I., Shalmon B., Addadi Y., Sharan R., Gal-Yam E., Barshack I. & Geiger T. (2025). Integrated spatial proteomic analysis of breast cancer heterogeneity unravels cancer cell phenotypic plasticity.  Nature Communications. 2025 Dec , 16 (1).
  2. Passini F. S., Bornstein B., Rubin S., Kuperman Y., Krief S., Masschelein E., Mehlman T., Brandis A., Addadi Y., Shalom S. H. O., Richter E. A., Yardeni T., Tirosh A., De Bock K. & Zelzer E. (2025). Piezo2 in sensory neurons regulates systemic and adipose tissue metabolism.  Cell Metabolism. 2025 Apr 1 , 37 (4):987-1000.e6.
  3. Shvefel S. C., Pai J. A., Cao Y., Pal L. R., Bartok O., Levy R., Zemanek M. J., Weller C., Herzog E., Yao W., Hiam-Galvez K. J., Cheng K., Yin Y., Du P. P., Raposo C. J., Gumpert N., Welti M., Martínez Gómez J. M., Sella F., Yakubovich E., Orr I., Ben-Dor S., Oren R., Fellus-Alyagor L., Golani O., Brenner O. J., Salame T. M., Zerbib M., Goliand I., Ranmar D., Savchenko I., Ketrarou N., Schäffer A. A., Dahan R., Levesque M. P., Ruppin E., Satpathy A. T. & Samuels Y. (2025). Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma.  Cancer Discovery. 2025 Mar 1 , 15 (3):553-577.
  4. Gigi E., Gavert N., Raijman-Nagar L., Zwang Y., Zemach H., Livyatan I., Levy-Barda A., Laviv Y., Kanner A. A., Amiel A., Siegal T., Leibovici A., Selezen I., Badran O., Zohar Y., Safadi E., Prather L. L., Helfer C. R., Castro P., Barshack I., Dadosh T., Levin-Zaidman S., Goliand I., Golani O., Horn S., Mandel J. J., Shental N., Shai A., Yust-Katz S. & Straussman R. (2025). Characterization of the tumor microbiome of brain metastases and glioblastoma reveals tumor-type-specific and location-specific microbial signatures.  Nature Reviews Cancer. 2025 Nov 14 , 6 (11):1761-1776.
  5. Gigi E., Gavert N., Raijman-Nagar L., Zwang Y., Zemach H., Livyatan I., Levy-Barda A., Laviv Y., Kanner A. A., Amiel A., Siegal T., Leibovici A., Selezen I., Badran O., Zohar Y., Safadi E., Prather L. L., Helfer C. R., Castro P., Barshack I., Dadosh T., Levin-Zaidman S., Goliand I., Golani O., Horn S., Mandel J. J., Shental N., Shai A., Yust-Katz S. & Straussman R. (2025). Characterization of the tumor microbiome of brain metastases and glioblastoma reveals tumor-type-specific and location-specific microbial signatures.  Nature Reviews Cancer. 2025 Nov 14 , 6 (11):1761-1776.
  6. Chourasia S., Petucci C., Shoffler C., Abbasian D., Wang H., Han X., Sivan E., Brandis A., Mehlman T., Malitsky S., Itkin M., Sharp A., Rotkopf R., Dassa B., Regev L., Zaltsman Y. & Gross A. (2025). MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis.  EMBO Journal. 2025 Feb 17 , 44 (4):1007-1038.
  7. Shoshani-Haye K., Friedlander G., Golani O., Almeida-Correa S., Shemesh Y. & Chen A. (2025). Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities.  Neurobiology of Stress. 2025 Sept , 38 .
  8. Abutbul R. E., Jardon-Alvarez D., Houben L., Golani O., Sivan E., Carmieli R., Kaminker I. & Leskes M. (2025). Metal Ion Dynamic Nuclear Polarization in Mn(II)-Doped CdS Nanocrystals: Atomic-Scale Investigation of the Dopant and Its Host.  ACS Nano. 2025 May 13 , 19 (18):17640-17652.
  9. Yilmaz A., Gurhan G., Comar M. Y., Viukov S., Serfaty I., Gayretli M., Golenchenko S., Lokshtanov D., Ashouokhi S., Polanco A., Berlad I., Ha T. W., Aguilera-Castrejon A., Tarazi S., Cohen M., Livnat N., Kumar K., Cholakkal H., Levy N., Yosef N., Khatib N., Kakun R. R., Kedmi M., Nachman I. B., Keren-Shaul H., Addadi Y., Orenbuch A. H., Korovin K., Molchadsky A., Hochedlinger K., Gafni O., Maza I., Novershtern N., Oldak B. & Hanna J. H. (2025). Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs.  Cell Stem Cell. 2025 Aug 7 , 32 (10):1545-1562.e12.
  10. Peer L., Dym O., Elad N., Tirosh A., Jacobovitch J., Sivan E., Angel M., Albeck S., Schuldiner M., Peleg Y. & Zalckvar E. (2025). A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.  Journal of Cell Science. 2025 Jun , 138 (12).
  11. Prasad P. K., Toraskar S., Khan S., Granot T., Sirkis Y. F., Yardeni E. H., Albeck S., Unger T., Petrovich-Kopitman E., Addadi Y., Raigawali R., Anand S., Vishweshwara S. S., Shanthamurthy C. D., Oppenheimer-Low N., Kikkeri R., Avinoam O., Motiei L. & Margulies D. (2025). Low-Background His-Tag-Targeting Probes for Turn-On Fluorescence Detection of Cell Surface Proteins and Their Binding Interactions.  Small. 2025 Jul 4 , 21 (33).
  12. Abutbul R. E., Jardon-Alvarez D., Houben L., Golani O., Sivan E., Carmieli R., Kaminker I. & Leskes M. (2025). Metal Ion Dynamic Nuclear Polarization in Mn(II)-Doped CdS Nanocrystals: Atomic-Scale Investigation of the Dopant and Its Host.  ACS Nano. 2025 May 13 , 19 (18):17640-17652.
  13. Kim J. S., Trzebanski S., Shin S. H., Schori L., Frumer Friedman G. R., Ilani N. C., Kadam A., Vicario R., Aust O., Bugaeva P., Piatek S., Ismajli L. K., Hoffmann C. J., Boura-Halfon S., Kaushansky N., Golani O., Solomon A., Avraham R., Shlush L. & Jung S. (2025). Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice.  Cell Reports. 2025 May 27 , 44 (5).
  14. Shvefel S. C., Pai J. A., Cao Y., Pal L. R., Bartok O., Levy R., Zemanek M. J., Weller C., Herzog E., Yao W., Hiam-Galvez K. J., Cheng K., Yin Y., Du P. P., Raposo C. J., Gumpert N., Welti M., Martínez Gómez J. M., Sella F., Yakubovich E., Orr I., Ben-Dor S., Oren R., Fellus-Alyagor L., Golani O., Brenner O. J., Salame T. M., Zerbib M., Goliand I., Ranmar D., Savchenko I., Ketrarou N., Schäffer A. A., Dahan R., Levesque M. P., Ruppin E., Satpathy A. T. & Samuels Y. (2025). Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma.  Cancer Discovery. 2025 Mar 1 , 15 (3):553-577.
  15. Miyara S., Adler M., Umansky K. B., Häußler D., Bassat E., Divinsky Y., Elkahal J., Kain D., Lendengolts D., Ramirez Flores R. O., Bueno-Levy H., Golani O., Shalit T., Gershovits M., Weizman E., Genzelinakh A., Kimchi D. M., Shakked A., Zhang L., Wang J., Baehr A., Petrover Z., Sarig R., Dorn T., Moretti A., Saez-Rodriguez J., Kupatt C., Tanaka E. M., Medzhitov R., Krüger A., Mayo A., Alon U. & Tzahor E. (2025). Cold and hot fibrosis define clinically distinct cardiac pathologies.  Cell Systems. 2025 Mar 19 , 16 (3).
  16. Kagan Ben Tikva S., Gurwitz N., Sivan E., Hirsch D., Hezroni-Barvyi H., Biram A., Moss L., Wigoda N., Egozi A., Monziani A., Golani O., Gross M., Tenenbaum A. & Shulman Z. (2024). T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection.  Science immunology. 2024 Mar 29 , 9 (93).
  17. Harnik Y., Yakubovsky O., Hoefflin R., Novoselsky R., Bahar Halpern K., Barkai T., Korem Kohanim Y., Egozi A., Golani O., Addadi Y., Kedmi M., Keidar Haran T., Levin Y., Savidor A., Keren-Shaul H., Mayer C., Pencovich N., Pery R., Shouval D. S., Tirosh I., Nachmany I. & Itzkovitz S. (2024). A spatial expression atlas of the adult human proximal small intestine.  Nature. 2024 Aug 29 , 632 (8027):1101-1109.
  18. Harnik Y., Yakubovsky O., Hoefflin R., Novoselsky R., Bahar Halpern K., Barkai T., Korem Kohanim Y., Egozi A., Golani O., Addadi Y., Kedmi M., Keidar Haran T., Levin Y., Savidor A., Keren-Shaul H., Mayer C., Pencovich N., Pery R., Shouval D. S., Tirosh I., Nachmany I. & Itzkovitz S. (2024). A spatial expression atlas of the adult human proximal small intestine.  Nature. 2024 Aug 29 , 632 (8027):1101-1109.
  19. Barnea-Zohar M., Stein M., Reuven N., Winograd-Katz S., Lee S., Addadi Y., Arman E., Tuckermann J., Geiger B. & Elson A. (2024). SNX10 regulates osteoclastogenic cell fusion and osteoclast size in mice.  Journal of Bone and Mineral Research. 2024 Oct , 39 (10):1503-1517.
  20. Trzebanski S., Kim J., Larossi N., Raanan A., Kancheva D., Bastos J., Haddad M., Solomon A., Sivan E., Aizik D., Kralova J. S., Gross-Vered M., Boura-Halfon S., Lapidot T., Alon R., Movahedi K. & Jung S. (2024). Classical monocyte ontogeny dictates their functions and fates as tissue macrophages.  Immunity. 2024 Jun 11 , 57 (6):1225-1242.e6.