Protein Expression Publications

  1. Miodownik I., Solozabal R., OHagan M. P., Albeck S., Peleg Y., Takac M. & Afek A. (2025). DNA methylation shapes transcription factor binding beyond canonical CpG contexts.  Proceedings of the National Academy of Sciences - PNAS. 2025 Dec 23 , 122 (51).
  2. Yado S., Zoabi R., Brezinger-Dayan K., Albeck S., Unger T., Meiron M., Eisenberg G., Nahmad A. D., Gilat A. T., Besser M. J. & Geiger B. (2025). Differential effects of immobilized CCL21 and ICAM1 on TILs with distinct expansion properties.  Frontiers in Immunology. 2025 Oct 3 , 16 .
  3. Razi S. G., Withanage T. J., Krichevsky O., Wachtel E., Peleg Y., Albeck S. & Patchornik G. (2025). Fluorescent supramolecular fibers and sheets built from doubly hexa-His tagged mCherry proteins conjugated by divalent metal cations.  International Journal of Biological Macromolecules. 2025 Oct , 327 .
  4. Feigelson S. W., Dadosh T., Levi N., Sapoznikov A., Weinstein-Marom H., Blokon-Kogan D., Avraham Y., Unger T., Gross G., Dahan R. & Alon R. (2025). CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens.  Frontiers in Immunology. 2025 Feb 10 , 16 .
  5. Weinreb E., McBride J. M., Siek M., Rougemont J., Renault R., Peleg Y., Unger T., Albeck S., Fridmann-Sirkis Y., Lushchekina S., Sussman J. L., Grzybowski B. A., Zocchi G., Eckmann J. P., Moses E. & Tlusty T. (2025). Enzymes as viscoelastic catalytic machines.  Nature Physics. 2025 Mar 28 , 21 (5):787-798.
  6. Weinreb E., McBride J. M., Siek M., Rougemont J., Renault R., Peleg Y., Unger T., Albeck S., Fridmann-Sirkis Y., Lushchekina S., Sussman J. L., Grzybowski B. A., Zocchi G., Eckmann J. P., Moses E. & Tlusty T. (2025). Enzymes as viscoelastic catalytic machines.  Nature Physics. 2025 Mar 28 , 21 (5):787-798.
  7. Prasad P. K., Toraskar S., Khan S., Granot T., Sirkis Y. F., Yardeni E. H., Albeck S., Unger T., Petrovich-Kopitman E., Addadi Y., Raigawali R., Anand S., Vishweshwara S. S., Shanthamurthy C. D., Oppenheimer-Low N., Kikkeri R., Avinoam O., Motiei L. & Margulies D. (2025). Low-Background His-Tag-Targeting Probes for Turn-On Fluorescence Detection of Cell Surface Proteins and Their Binding Interactions.  Small. 2025 Jul 4 , 21 (33).
  8. Peer L., Dym O., Elad N., Tirosh A., Jacobovitch J., Sivan E., Angel M., Albeck S., Schuldiner M., Peleg Y. & Zalckvar E. (2025). A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.  Journal of Cell Science. 2025 Jun , 138 (12).
  9. Berman P., de Haro L. A., Cavaco A. R., Panda S., Dong Y., Kuzmich N., Lichtenstein G., Peleg Y., Harat H., Jozwiak A., Cai J., Heinig U., Meir S., Rogachev I. & Aharoni A. (2024). The biosynthetic pathway of the hallucinogen mescaline and its heterologous reconstruction.  Molecular Plant. 2024 Jul 1 , 17 (7):1129-1150.
  10. Quinn S., Zhang N., Fenton T. A., Brusel M., Muruganandam P., Peleg Y., Giladi M., Haitin Y., Lerche H., Bassan H., Liu Y., Ben-Shalom R. & Rubinstein M. (2024). Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.  Biochimica et Biophysica Acta - Molecular Basis of Disease. 2024 Jun , 1870 (5).
  11. Halfin O., Avram L., Albeck S., Unger T., Motiei L. & Margulies D. (2024). Unnatural Enzyme Activation by a Metal-Responsive Regulatory Protein.  Chemical Science. 2024 Sept 21 , 15 (35):14209-14217.
  12. Osher E., Anis Y., Singer-Shapiro R., Urshanski N., Unger T., Albeck S., Bogin O., Weisinger G., Kohen F., Valevski A., Fattal-Valevski A., Sagi L., Weitman M., Shenberger Y., Sagiv N., Navon R., Wilchek M. & Stern N. (2024). Treating late-onset Tay Sachs disease: Brain delivery with a dual trojan horse protein.  Molecular Therapy Methods and Clinical Development. 2024 Sept 12 , 32 (3).
  13. Sen S., Bhowmik P., Tiwari S., Peleg Y. & Bandyopadhyay B. (2024). Versatility of reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) from diagnosis of early pathological infection to mutation detection in organisms.  Molecular Biology Reports. 2024 Jan 25 , 51 (1).
  14. Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D. (2024). C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.  Biophysical Journal. 2024 Jan 16 , 123 (2):172-183.
  15. Lal M., Kesselman E., Wachtel E., Kleinerman O., Peleg Y., Albeck S., Majhi K., Sheves M. & Patchornik G. (2024). His-tag based supramolecular biopolymerization.  Scientific Reports. 2024 Nov 16 , 14 .
  16. Peri L., Matzov D., Huxley D. R., Rainish A., Fierro F., Sapir L., Pfeiffer T., Waterloo L., Hübner H., Peleg Y., Gmeiner P., McCormick P. J., Weikert D., Niv M. Y. & Shalev-Benami M. (2024). A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR.  Nature Communications. 2024 Nov 18 , 15 .
  17. Herynek Š., Svoboda J., Huličiak M., Peleg Y., Škultétyová Ľ., Mikulecký P. & Schneider B. (2024). Increasing recombinant protein production in E. coli via FACS-based selection of N-terminal coding DNA libraries.  FEBS Journal. 2024 Dec 26 , 292 (5):1070-1085.
  18. Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z. (2024). LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.  Nature Communications. 2024 Aug 8 , 15 .
  19. Pokorna S., Khersonsky O., Lipsh-Sokolik R., Goldenzweig A., Nielsen R., Ashani Y., Peleg Y., Unger T., Albeck S., Dym O., Tirosh A., Tarayra R., Hocquemiller M., Laufer R., Ben-Dor S., Silman I., Sussman J. L., Fleishman S. J. & Futerman A. H. (2023). Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.  FEBS Journal. 2023 Jul , 290 (13):3383-3399.
  20. Gould N. L., Scherer G. R., Carvalho S., Shurrush K., Kayyal H., Edry E., Elkobi A., David O., Foqara M., Thakar D., Pavesi T., Sharma V., Walker M., Maitland M., Dym O., Albeck S., Peleg Y., Germain N., Babaev I., Sharir H., Lalzar M., Shklyar B., Hazut N., Khamaisy M., Lévesque M., Lajoie G., Avoli M., Amitai G., Lefker B., Subramanyam C., Shilton B., Barr H. & Rosenblum K. (2023). Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimers disease phenotype in mice.  Journal of Clinical Investigation. 2023 Oct 2 , 133 (19).