Metabolic Profiling Publications

  1. Lee J. S., Adler L., Karathia H., Carmel N., Rabinovich S., Auslander N., Keshet R., Stettner N., Silberman A., Agemy L., Helbling D., Eilam R., Sun Q., Brandis A., Malitsky S., Itkin M., Weiss H., Pinto S., Kalaora S., Levy R., Barnea E., Admon A., Dimmock D., Stern-Ginossar N., Scherz A., Nagamani S. C. S., Unda M., Wilson D. M., Elhasid R., Carracedo A., Samuels Y., Hannenhalli S., Ruppin E. & Erez A. (2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.  Cell. 2018 Sept , 174 (6):1559-1570.e22.
  2. Cohen H., Hacham Y., Panizel I., Rogachev I., Aharoni A. & Amir R. (2017). Repression of CYSTATHIONINE gamma-SYNTHASE in Seeds Recruits the S-Methylmethionine Cycle.  Plant Physiology. 2017 Jul , 174 (3):1322-1333.
  3. Nir I., Shohat H., Panizel I., Olszewski N., Aharoni A. & Weiss D. (2017). The Tomato DELLA Protein PROCERA Acts in Guard Cells to Promote Stomatal Closure.  Plant Cell. 2017 Dec , 29 (12):3186-3197.
  4. Shahaf N., Rogachev I., Heinig U., Meir S., Malitsky S., Battat M., Wyner H., Zheng S., Wehrens R. & Aharoni A. (2016). The WEIZMASS spectral library for high-confidence metabolite identification..  Nature Communications. 2016, 7 :12423.
  5. Itkin M., Davidovich-Rikanati R., Cohen S., Portnoy V., Doron-Faigenboim A., Oren E., Freilich S., Tzuri G., Baranes N., Shen S., Petreikov M., Sertchook R., Ben-Dor S., Gottlieb H., Hernandez A., Nelson D., Paris H., Tadmor Y., Burger Y., Lewinsohn E., Katzir N. & Schaffer A. (2016). The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.  Proceedings of the National Academy of Sciences of the United States of America. 2016 Nov , 113 (47):E7619-E7628.
  6. Malitsky S., Ziv C., Rosenwasser S., Zheng S., Schatz D., Porat Z., Ben-Dor S., Aharoni A. & Vardi A. (2016). Viral infection of the marine alga Emiliania huxleyi triggers lipidome remodeling and induces the production of highly saturated triacylglycerol.  New Phytologist. 2016 Apr , 210 (1):88-96.
  7. Lashbrooke J., Cohen H., Levy-Samocha D., Tzfadia O., Panizel I., Zeisler V., Massalha H., Stern A., Trainotti L., Schreiber L., Costa F. & Aharoni A. (2016). MYB107 and MYB9 Homologs Regulate Suberin Deposition in Angiosperms.  Plant Cell. 2016 Sept , 28 (9):2097-2116.
  8. Ziv C., Malitsky S., Othman A., Ben-Dor S., Wei Y., Zheng S., Aharoni A., Hornemann T. & Vardi A. (2016). Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga..  Proceedings of the National Academy of Sciences of the United States of America. 2016 Mar , 113 (13):E1907-16.
  9. Breitel D. A., Chappell-Maor L., Meir S., Panizel I., Puig C. P., Hao Y., Yifhar T., Yasuor H., Zouine M., Bouzayen M., Richart A. G., Rogachev I. & Aharoni A. (2016). AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.  PLoS Genetics. 2016 Mar , 12 (3).
  10. Cohen S., Itkin M., Yeselson Y., Tzuri G., Portnoy V., Harel-Baja R., Lev S., Sa'ar U., Davidovitz-Rikanati R., Baranes N., Bar E., Wolf D., Petreikov M., Shen S., Ben-Dor S., Rogachev I., Aharoni A., Ast T., Schuldiner M., Belausov E., Eshed R., Ophir R., Sherman A., Frei B., Neuhaus H. E., Xu Y., Fei Z., Giovannoni J., Lewinsohn E., Tadmor Y., Paris H. S., Katzir N., Burger Y. & Schaffer A. A. (2014). The PH gene determines fruit acidity and contributes to the evolution of sweet melons.  Nature Communications. 2014 Jun , 5 .
  11. Itkin M., Heinig U., Tzfadia O., Bhide A. J., Shinde B. A., Cardenas P. D., Bocobza S. E., Unger T., Malitsky S., Finkers R., Tikunov Y., Bovy A., Chikate Y. R., Singh P., Rogachev I., Beekwilder J., Giri A. P. & Aharoni A. (2013). Biosynthesis of Antinutritional Alkaloids in Solanaceous Crops Is Mediated by Clustered Genes.  Science. 2013 Jul , 341 (6142):175-179.
  12. Cohen S., Tzuri G., Harel-Beja R., Itkin M., Portnoy V., Sa'ar U., Lev S., Yeselson L., Petrikov M., Rogachev I., Aharoni A., Ophir R., Tadmor Y., Lewinsohn E., Burger Y., Katzir N. & Schaffer A. A. (2012). Co-mapping studies of QTLs for fruit acidity and candidate genes of organic acid metabolism and proton transport in sweet melon (Cucumis melo L.).  Theoretical And Applied Genetics. 2012 Jul , 125 (2):343-353.
  13. Itkin M., Rogachev I., Alkan N., Rosenberg T., Malitsky S., Masini L., Meir S., Iijima Y., Aoki K., de Vos V. R., Prusky D., Burdman S., Beekwilder J. & Aharoni A. (2011). GLYCOALKALOID METABOLISM1 Is Required for Steroidal Alkaloid Glycosylation and Prevention of Phytotoxicity in Tomato.  Plant Cell. 2011 Dec , 23 (12):4507-4525.
  14. Nashilevitz S., Melamed-Bessudo C., Izkovich Y., Rogachev I., Osorio S., Itkin M., Adato A., Pankratov I., Hirschberg J., Fernie A. R., Wolf S., Usadel B., Levy A., Rumeau D. & Aharoni A. (2010). An Orange Ripening Mutant Links Plastid NAD(P)H Dehydrogenase Complex Activity to Central and Specialized Metabolism during Tomato Fruit Maturation.  Plant Cell. 2010 Jun , 22 (6):1977-1997.
  15. Itkin M., Seybold H., Breitel D., Rogachev I., Meir S. & Aharoni A. (2009). TOMATO AGAMOUS-LIKE 1 is a component of the fruit ripening regulatory network.  Plant Journal. 2009 Dec , 60 (6):1081-1095.
  16. Itkin M. & Aharoni A. (2009). Bioengineering.  . 2009, :435-473.
  17. Amitay-Sadovsky E., Zheng S., Smith J. & Wagner D. H. (1998). Directional indentation of transcrystalline polypropylene.  Acta Polymerica. 1998 Nov , 49 (11-Oct):588-593.