Protein Analysis Publications

  1. Tennenhouse A., Khmelnitsky L., Khalaila R., Yeshaya N., Noronha A., Lindzen M., Makowski E. K., Zaretsky I., Sirkis Y. F., Galon-Wolfenson Y., Tessier P. M., Abramson J., Yarden Y., Fass D. & Fleishman S. J. (2024). Computational optimization of antibody humanness and stability by systematic energy-based ranking.  Nature Biomedical Engineering. 2024 Jan , 8 (1):30-44.
  2. Khersonsky O., Goldsmith M., Zaretsky I., Hamer-Rogotner S., Dym O., Unger T., Yona M., Fridmann-Sirkis Y. & Fleishman S. J. (2023). Stable Mammalian Serum Albumins Designed for Bacterial Expression.  Journal of Molecular Biology. 2023 Sept 1 , 435 (17).
  3. Bakavayev S., Stavsky A., Argueti-Ostrovsky S., Yehezkel G., Fridmann-Sirkis Y., Barak Z., Gitler D., Israelson A. & Engel S. (2023). Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis.  Brain. 2023 Nov 1 , 146 (11):4594-4607.
  4. Suss O., Halfin O., Porat Z., Fridmann Sirkis Y., Motiei L. & Margulies D. (2023). Artificial Protein Crosstalk with a Molecule that Exchanges Binding Partners.  Angewandte Chemie - International Edition. 2023 Nov 27 , .
  5. Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D. (2023). C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.  Biophysical Journal. 2023 Dec 10 , .
  6. Nuta G. C., Gilad Y., Goldberg N., Meril S., Bahlsen M., Carvalho S., Kozer N., Barr H., Fridmann Sirkis Y., Hercík K., Břehová P., Nencka R., Bialik S., Eisenstein M. & Kimchi A. (2023). Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction.  Autophagy. 2023 Feb 22 , 19 (8):2372-2385.
  7. Füzesi-Levi M. G., Ben-Nissan G., Listov D., Fridmann Sirkis Y., Hayouka Z., Fleishman S. & Sharon M. (2023). The C-terminal tail of CSNAP attenuates the CSN complex.  Life Science Alliance. 2023 Oct 1 , 6 (10).
  8. Reznik N., Gallo A. D., Rush K. W., Javitt G., Fridmann-Sirkis Y., Ilani T., Nairner N. A., Fishilevich S., Gokhman D., Chacón K. N., Franz K. J. & Fass D. (2022). Intestinal mucin is a chaperone of multivalent copper.  Cell. 2022 Oct 27 , 185 (22):4206-4215.
  9. Hatai J., Prasad P. K., Lahav-Mankovski N., Oppenheimer-Low N., Unger T., Sirkis Y. F., Dadosh T., Motiei L. & Margulies D. (2021). Assessing changes in the expression levels of cell surface proteins with a turn-on fluorescent molecular probe.  Chemical Communications. 2021 Feb 21 , 57 (15):1875-1878.
  10. Dopico-López A., Pérez-Mato M., da Silva-Candal A., Iglesias-Rey R., Rabinkov A., Bugallo-Casal A., Sobrino T., Mirelman D., Castillo J. & Campos F. (2021). Inhibition of endogenous blood glutamate oxaloacetate transaminase enhances the ischemic damage.  Translational research : the journal of laboratory and clinical medicine. 2021 Apr , 230 :68-81.
  11. Longo L. M., Despotovic D., Weil-Ktorza O., Walker M. J., Jablonska J., Fridmann-Sirkis Y., Varani G., Metanis N. & Tawfik D. S. (2020). Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion.  Proceedings of the National Academy of Sciences of the United States of America. 2020 Jul 7 , 117 (27):15731-15739.
  12. Peri-Naor R., Pode Z., Lahav-Mankovski N., Rabinkov A., Motiei L. & Margulies D. (2020). Glycoform Differentiation by a Targeted, Self-Assembled, Pattern-Generating Protein Surface Sensor.  Journal of the American Chemical Society. 2020 Sept 16 , 142 (37):15790-15798.
  13. Sapir T., Levy T., Kozer N., Shin I., Zamor V., Haffner-Krausz R., McGlade J. C. & Reiner O. (2018). Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases.  Cerebral Cortex. 2018 Sept , 28 (9):3115-3128.
  14. Rotem O., Nesper J., Borovok I., Gorovits R., Kolot M., Pasternak Z., Shin I., Glatter T., Pietrokovski S., Jenal U. & Jurkevitch E. (2016). An extended cyclic di-GMP network in the predatory bacterium Bdellovibrio bacteriovorus.  Journal of Bacteriology. 2016, 198 (1):127-137.
  15. Fridmann-Sirkis Y., Milrot E., Mutsafi Y., Ben-Dor S., Levin Y., Savidor A., Kartvelishvily E. & Minsky A. (2016). Efficiency in complexity: Composition and dynamic nature of mimivirus replication factories.  Journal of Virology. 2016, 90 (21):10039-10047.
  16. Milrot E., Mutsafi Y., Fridmann Sirkis S. Y., Shimoni E., Rechav K., Gurnon J. R., Van Etten E. J. L. & Minsky A. (2016). Virus-host interactions: Insights from the replication cycle of the large Paramecium bursaria chlorella virus.  Cellular Microbiology. 2016 Jan 1 , 18 (1):3-16.
  17. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). Sensing Protein Surfaces with Targeted Fluorescent Receptors.  Chemistry (Weinheim an der Bergstrasse, Germany). 2015 Nov 1 , 21 (45):15981-15987.
  18. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). [Cover Profile] Sensing Protein Surfaces with Targeted Fluorescent Receptors..  Chemistry (Weinheim an der Bergstrasse, Germany). 2015 Nov , 21 (45):15873-15873.
  19. Fridmann-Sirkis Y., Stern S., Elgart M., Galili M., Zeisel A., Shental N. & Soen Y. (2014). Delayed development induced by toxicity to the host can be inherited by a bacterial-dependent, transgenerational effect.  Frontiers in Genetics. 2014 Feb 25 , 5 (FEB).
  20. Mutsafi Y., Fridmann-Sirkis Y., Milrot E., Hevroni L. & Minsky A. (2014). Infection cycles of large DNA viruses: Emerging themes and underlying questions.  Virology. 2014 Oct 1 , 466-467 :3-14.