Protein Analysis Publications

  1. Lev N., Fridmann Sirkis S. Y., Blank L., Bitler A., Epand R. F., Epand R. M. & Shai Y. (2009). Conformational Stability and Membrane Interaction of the Full-Length Ectodomain of HIV-1 gp41: Implication for Mode of Action.  Biochemistry. 2009 Apr , 48 (14):3166-3175.
  2. Horev-Azaria L., Eliav S., Izigov N., Pri-Chen S., Mirelman D., Miron T., Rabinkov A., Wilchek M., Jacob-Hirsch J., Amariglio N. & Savion N. (2009). Allicin up-regulates cellular glutathione level in vascular endothelial cells.  European Journal of Nutrition. 2009 Mar , 48 (2):67-74.
  3. Weiner L., Shin I., Shimon L. J. W., Miron T., Wilchek M., Mirelman D., Frolow F. & Rabinkov A. (2009). Thiol-disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum).  Protein Science. 2009 Jan , 18 (1):196-205.
  4. Miron T., Arditti F., Konstantinovski L., Rabinkov A., Mirelman D., Berrebi A. & Wilchek M. (2009). Novel derivatives of 6-mercaptopurine: Synthesis, characterization and antiproliferative activities of S-allylthio-mercaptopurines.  European Journal of Medicinal Chemistry. 2009 Feb , 44 (2):541-550.
  5. Bendikov T. A., Rabinkov A., Karakouz T., Vaskevich A. & Rubinstein I. (2008). Biological sensing and interface design in gold island film based localized plasmon transducers.  Analytical Chemistry. 2008 Oct , 80 (19):7487-7498.
  6. Prager-Khoutorsky M., Goncharov I., Rabinkov A., Mirelman D., Geiger B. & Bershadsky A. D. (2007). Allicin inhibits cell polarization, migration and division via its direct effect on microtubules.  Cytoskeleton. 2007 May , 64 (5):321-337.
  7. Lorin A., Charloteaux B., Fridmann Sirkis S. Y., Thomas A., Shai Y. & Brasseur R. (2007). Mode of membrane interaction and fusogenic properties of a de Novo transmembrane model peptide depend on the length of the hydrophobic core.  Journal of Biological Chemistry. 2007 Jun , 282 (25):18388-18396.
  8. Shimon L. J. W., Rabinkov A., Shine I., Miron T., Mirelman D., Wilchek M. & Frolow F. (2007). Two structures of alliinase from Alliium sativum L.: Apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor.  Journal of Molecular Biology. 2007 Feb , 366 (2):611-625.
  9. Novick D., Rubinstein M., Azam T., Rabinkov A., Dinarello C. & Kim S. (2006). Proteinase 3 is an IL-32 binding protein.  Proceedings of the National Academy of Sciences of the United States of America. 2006 Feb , 103 (9):3316-3321.
  10. Miron T., SivaRaman H., Rabinkov A., Mirelman D. & Wilchek M. (2006). A method for continuous production of allicin using immobilized alliinase.  Analytical Biochemistry. 2006 Apr , 351 (1):152-154.
  11. Zik M., Fridmann Sirkis S. Y. & Fromm H. (2006). C-terminal residues of plant glutamate decarboxylase are required for oligomerization of a high-molecular weight complex and for activation by calcium/calmodulin.  Biochimica Et Biophysica Acta-Proteins And Proteomics. 2006 May , 1764 (5):872-876.
  12. Arditti F., Rabinkov A., Miron T., Reisner Y., Berrebi A., Wilchek M. & Mirelman D. (2005). Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.  Molecular Cancer Therapeutics. 2005 Feb , 4 (2):325-331.
  13. Oron-Herman M., Rosenthal T., Mirelman D., Miron T., Rabinkov A., Wilchek M. & Sela B. (2005). The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome.  Atherosclerosis. 2005 Dec , 183 (2):238-243.
  14. Gonen A., Harats D., Rabinkov A., Miron T., Mirelman D., Wilchek M., Weiner L., Ulman E., Levkovitz H., Ben-Shushan D. & Shaish A. (2005). The antiatherogenic effect of allicin: Possible mode of action.  Pathobiology. 2005, 72 (6):325-334.
  15. Patya M., Zahalka M., Vanichkin A., Rabinkov A., Miron T., Mirelman D., Wilchek M., Lander H. & Novogrodsky A. (2004). Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21(ras).  International Immunology. 2004 Feb , 16 (2):275-281.
  16. Sela U., Ganor S., Hecht I., Brill A., Miron T., Rabinkov A., Wilchek M., Mirelman D., Lider O. & Hershkoviz R. (2004). Allicin inhibits SDF-1 alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression.  Immunology. 2004 Apr , 111 (4):391-399.
  17. Miron T., Bercovici T., Rabinkov A., Wilchek M. & Mirelman D. (2004). [H-3]Allicin: preparation and applications.  Analytical Biochemistry. 2004 Aug , 331 (2):364-369.
  18. Miron T., Rabinkov A., Peleg E., Rosenthal T., Mirelman D. & Wilchek M. (2004). Allylmercaptocaptopril: A new antihypertensive drug.  American Journal of Hypertension. 2004 Jan , 17 (1):71-73.
  19. Shadkchan Y., Shemesh E., Mirelman D., Miron T., Rabinkov A., Wilchek M. & Osherov N. (2004). Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis.  Journal of Antimicrobial Chemotherapy. 2004 May , 53 (5):832-836.
  20. Miron T., Rabinkov A., Peleg E., Rosenthal T., Mirelman D. & Wilchek M. (2003). Allylmercapto-captopril, a new antihypertensive drug, its preparation and properties.  American Journal of Hypertension. 2003 May , 16 (5):128A-128A.