DNA Manipulation Publications

  1. Sen S., Bhowmik P., Tiwari S., Peleg Y. & Bandyopadhyay B. (2024). Versatility of reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) from diagnosis of early pathological infection to mutation detection in organisms.  Molecular Biology Reports. 2024 Jan 25 , 51 .
  2. Khersonsky O., Goldsmith M., Zaretsky I., Hamer-Rogotner S., Dym O., Unger T., Yona M., Fridmann-Sirkis Y. & Fleishman S. J. (2023). Stable Mammalian Serum Albumins Designed for Bacterial Expression.  Journal of Molecular Biology. 2023 Sept 1 , 435 (17).
  3. Franz F., Tapia-Rojo R., Winograd-Katz S., Boujemaa-Paterski R., Li W., Unger T., Albeck S., Aponte-Santamaria C., Garcia-Manyes S., Medalia O., Geiger B. & Gräter F. (2023). Allosteric activation of vinculin by talin.  Nature Communications. 2023 Jul 18 , 14 (1).
  4. Gould N. L., Scherer G. R., Carvalho S., Shurrush K., Kayyal H., Edry E., Elkobi A., David O., Foqara M., Thakar D., Pavesi T., Sharma V., Walker M., Maitland M., Dym O., Albeck S., Peleg Y., Germain N., Babaev I., Sharir H., Lalzar M., Shklyar B., Hazut N., Khamaisy M., Lévesque M., Lajoie G., Avoli M., Amitai G., Lefker B., Subramanyam C., Shilton B., Barr H. & Rosenblum K. (2023). Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer’s disease phenotype in mice.  Journal of Clinical Investigation. 2023 Oct 2 , 133 (19).
  5. Pokorna S., Khersonsky O., Lipsh-Sokolik R., Goldenzweig A., Nielsen R., Ashani Y., Peleg Y., Unger T., Albeck S., Dym O., Tirosh A., Tarayra R., Hocquemiller M., Laufer R., Ben-Dor S., Silman I., Sussman J. L., Fleishman S. J. & Futerman A. H. (2023). Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.  The FEBS journal. 2023 Jul , 290 (13):3383-3399.
  6. Dym O., Aggarwal N., Ashani Y., Leader H., Albeck S., Unger T., Hamer-Rogotner S., Silman I., Tawfik D. S. & Sussman J. L. (2023). The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.  Acta Crystallographica Section D: Structural Biology. 2023 Nov , 79 (Pt 11):992-1009.
  7. Pokorna S., Khersonsky O., Lipsh-Sokolik R., Goldenzweig A., Nielsen R., Ashani Y., Peleg Y., Unger T., Albeck S., Dym O., Tirosh A., Tarayra R., Hocquemiller M., Laufer R., Ben-Dor S., Silman I., Sussman J. L., Fleishman S. J. & Futerman A. H. (2023). Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.  The FEBS journal. 2023 Jul , 290 (13):3383-3399.
  8. Schütz A., Bernhard F., Berrow N., Buyel J. F., Ferreira-da-Silva F., Haustraete J., van den Heuvel J., Hoffmann J. E., de Marco A., Peleg Y., Suppmann S., Unger T., Vanhoucke M., Witt S. & Remans K. (2023). A concise guide to choosing suitable gene expression systems for recombinant protein production.  STAR Protocols. 2023 Dec 15 , 4 (4).
  9. Schütz A., Bernhard F., Berrow N., Buyel J. F., Ferreira-da-Silva F., Haustraete J., van den Heuvel J., Hoffmann J. E., de Marco A., Peleg Y., Suppmann S., Unger T., Vanhoucke M., Witt S. & Remans K. (2023). A concise guide to choosing suitable gene expression systems for recombinant protein production.  STAR Protocols. 2023 Dec 15 , 4 (4).
  10. Oranges M., Giannoulis A., Vanyushkina A., Sirkis Y. F., Dalaloyan A., Unger T., Su X. C., Sharon M. & Goldfarb D. (2023). C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains.  Biophysical Journal. 2023 Dec 10 , .
  11. Allouche-Arnon H., Khersonsky O., Tirukoti N. D., Peleg Y., Dym O., Albeck S., Brandis A., Mehlman T., Avram L., Harris T., Yadav N. N., Fleishman S. J. & Bar-Shir A. (2022). Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.  Nature biotechnology. 2022 Jul , 40 (7):1143-1149.
  12. Bose T., Fridkin G., Davidovich C., Krupkin M., Dinger N., Falkovich A. H., Peleg Y., Agmon I., Bashan A. & Yonath A. (2022). Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds.  Nucleic Acids Research. 2022 Feb 7 , 50 (4):1815-1828.
  13. Bandyopadhyay B. & Peleg Y. (2022). Application of Restriction Free (RF) Cloning in Circular Permutation.  . 2022 Jun 22 , :149-163.
  14. Rozenberg A., Kaczmarczyk I., Matzov D., Vierock J., Nagata T., Sugiura M., Katayama K., Kawasaki Y., Konno M., Nagasaka Y., Aoyama M., Das I., Pahima E., Church J., Adam S., Borin V. A., Chazan A., Augustin S., Wietek J., Dine J., Peleg Y., Kawanabe A., Fujiwara Y., Yizhar O., Sheves M., Schapiro I., Furutani Y., Kandori H., Inoue K., Hegemann P., Beja O. & Shalev-Benami M. (2022). Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.  Nature Structural & Molecular Biology. 2022 Jun 1 , 29 (6):592-603.
  15. Sonawane P. D., Jozwiak A., Barbole R., Panda S., Abebie B., Kazachkova Y., Gharat S. A., Ramot O., Unger T., Wizler G., Meir S., Rogachev I., Doron-Faigenboim A., Petreikov M., Schaffer A., Giri A. P., Scherf T. & Aharoni A. (2022). 2-Oxoglutarate-Dependent Dioxygenases Drive Expansion of Steroidal Alkaloid Structural Diversity in the Genus Solanum.  The New Phytologist. 2022 May , 234 (4):1394-1410.
  16. Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z. (2022). Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.  The journal of Biological chemistry. 2022 May 1 , 298 (5).
  17. Yifrach E., Holbrook‐Smith D., Bürgi J., Othman A., Eisenstein M., Roermund C. W., Visser W., Tirosh A., Rudowitz M., Bibi C., Galor S., Weill U., Fadel A., Peleg Y., Erdmann R., Waterham H. R., Wanders R. J. A., Wilmanns M., Zamboni N., Schuldiner M. & Zalckvar E. (2022). Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions.  Molecular Systems Biology. 2022 Sept , 18 (9).
  18. Yifrach E., Rudowitz M., Cruz-Zaragoza L. D., Tirosh A., Gazi Z., Peleg Y., Kunze M., Eisenstein M., Schliebs W., Schuldiner M., Erdmann R. & Zalckvar E. (2022). Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.  Biological Chemistry. 2022 Oct 24 , 404 (2-3):121-133.
  19. Goldsmith M., Barad S., Peleg Y., Albeck S., Dym O., Brandis A., Mehlman T. & Reich Z. (2022). The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.).  RSC Chemical Biology. 2022 Mar 9 , 3 (3):320-333.
  20. Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M. (2021). Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes.  Journal of the American Chemical Society. 2021 Oct 20 , 143 (41):17261-17275.