Targeted Metabolomics Publications

  1. Stroganov S., Harris T., Alyagor L., Ben Moyal L., Plitman Mayo R., Golani O., Hirsch D., Ben-Dor S., Brandis A., Mehlman T., Kovo M., Biron-Shental T., Dekel N. & Neeman M. (2024). The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.  eLife. 2024 Feb 5 , 13 .
  2. Bahat A., Itzhaki E., Weiss B., Tolmasov M., Tsoory M., Kuperman Y., Brandis A., Shurrush K. A. & Dikstein R. (2024). Lowering mutant huntingtin by small molecules relieves Huntington’s disease symptoms and progression.  EMBO Molecular Medicine. 2024 Feb 19 , 16 (3):523-546.
  3. Garb J., Amitai G., Lu A., Ofir G., Brandis A., Mehlman T., Kranzusch P. J. & Sorek R. (2024). The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products.  PLoS ONE. 2024 Apr 18 , 19 (4 ).
  4. Brandis A., Roy D., Das I., Sheves M. & Eisenbach M. (2024). Uncommon opsin’s retinal isomer is involved in mammalian sperm thermotaxis.  Scientific Reports. 2024 May 10 , 14 .
  5. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jun 10 , .
  6. Moraïs S., Mazor M., Tovar-Herrera O., Zehavi T., Zorea A., Ifrach M., Bogumil D., Brandis A., Walter J., Elia N., Gur E. & Mizrahi I. (2024). Plasmid-encoded toxin defence mediates mutualistic microbial interactions.  Nature Microbiology. 2024 Jan , 9 :108-119.
  7. Uzonyi A., Dierks D., Nir R., Kwon O. S., Toth U., Barbosa I., Burel C., Brandis A., Rossmanith W., Le Hir H., Slobodin B. & Schwartz S. (2023). Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability.  Molecular Cell. 2023 Jan 19 , 83 (2):237-251.e7.
  8. Koh E., Chaturvedi A. K., Javitt G., Brandis A. & Fluhr R. (2023). Multiple paths of plant host toxicity are associated with the fungal toxin cercosporin.  Plant Cell And Environment. 2023 Aug , 46 (8):2542-2557.
  9. Barak-Gavish N., Dassa B., Kuhlisch C., Nussbaum I., Brandis A., Rosenberg G., Avraham R. & Vardi A. (2023). Bacterial lifestyle switch in response to algal metabolites.  eLife. 2023 Jan 24 , 12 .
  10. Rousset F., Yirmiya E., Nesher S., Brandis A., Mehlman T., Itkin M., Malitsky S., Millman A., Melamed S. & Sorek R. (2023). A conserved family of immune effectors cleaves cellular ATP upon viral infection.  Cell. 2023 Aug 17 , 186 (17):3619-3631.e13.
  11. Suzzi S., Croese T., Ravid A., Gold O., Clark A. R., Medina S., Kitsberg D., Adam M., Vernon K. A., Kohnert E., Shapira I., Malitsky S., Itkin M., Brandis A., Mehlman T., Salame T. M., Colaiuta S. P., Cahalon L., Slyper M., Greka A., Habib N. & Schwartz M. (2023). N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer’s disease mouse model.  Nature Communications. 2023 Dec , 14 (1).
  12. Nobs S. P., Kolodziejczyk A. A., Adler L., Horesh N., Botscharnikow C., Herzog E., Mohapatra G., Hejndorf S., Hodgetts R. J., Spivak I., Schorr L., Fluhr L., Kviatcovsky D., Zacharia A., Njuki S., Barasch D., Stettner N., Dori-Bachash M., Harmelin A., Brandis A., Mehlman T., Erez A., He Y., Ferrini S., Puschhof J., Shapiro H., Kopf M., Moussaieff A., Abdeen S. K. & Elinav E. (2023). Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.  Nature. 2023 Dec 21 , 624 (7992):645-652.
  13. Chourasia S., Petucci C., Wang H., Han X., Sivan E., Brandis A., Mehlman T., Malitsky S., Itkin M., Rotkopf R., Regev L., Zaltsman Y. & Gross A. (2023). High-energy demand and nutrient exhaustion in MTCH2 knockout cells.  BioRxiv. 2023 Dec 16 , .
  14. Duncan-Lowey B., Tal N., Johnson A. G., Rawson S., Mayer M. L., Doron S., Millman A., Melamed S., Fedorenko T., Kacen A., Brandis A., Mehlman T., Amitai G., Sorek R. & Kranzusch P. J. (2023). Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.  Cell. 2023 Mar 2 , 186 (5):987-998.
  15. Serger E., Luengo-Gutierrez L., Chadwick J. S., Kong G., Zhou L., Crawford G., Danzi M. C., Myridakis A., Brandis A., Bello A. T., Müller F., Sanchez-Vassopoulos A., De Virgiliis F., Liddell P., Dumas M. E., Strid J., Mani S., Dodd D. & Di Giovanni S. (2022). The gut metabolite indole-3 propionate promotes nerve regeneration and repair.  Nature (London). 2022 Jun 22 , 607 :585-592.
  16. Noronha A., Belugali Nataraj N., Sang Lee J., Zhitomirsky B., Oren Y., Oster S., Lindzen M., Mukherjee S., Will R., Ghosh S., Simoni-Nieves A., Verma A., Chatterjee R., Borgoni S., Robinson W., Sinha S., Brandis A., Kerr D. L., Wu W., Sekar A., Giri S., Chung Y., Drago-Garcia D., Danysh B. P., Lauriola M., Fiorentino M., Ardizzoni A., Oren M., Blakely C. M., Ezike J., Wiemann S., Parida L., Bivona T. G., Aqeilan R. I., Brugge J. S., Regev A., Getz G., Ruppin E. & Yarden Y. (2022). AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.  Cancer Discovery. 2022 Nov 1 , 12 (11):2666-2683.
  17. Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z. (2022). Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.  The journal of Biological chemistry. 2022 May 1 , 298 (5).
  18. Millman A., Melamed S., Leavitt A., Doron S., Bernheim A., Hör J., Garb J., Bechon N., Brandis A., Lopatina A., Ofir G., Hochhauser D., Stokar-Avihail A., Tal N., Sharir S., Voichek M., Erez Z., Ferrer J. L. M., Dar D., Kacen A., Amitai G. & Sorek R. (2022). An expanded arsenal of immune systems that protect bacteria from phages.  Cell Host and Microbe. 2022 Nov 9 , 30 (11):1556-1569e5.
  19. Brekelmans J., Dickman M. M., Verma S., Arba-Mosquera S., Goldschmidt R., Goz A., Brandis A., Berendschot T. T., Saelens I. E., Marcovich A. L., Scherz A. & Nuijts R. M. (2022). Excimer laser-assisted corneal epithelial pattern ablation for corneal cross-linking.  Acta Ophthalmologica. 2022 Jun , 100 (4):422-430.
  20. Goldsmith M., Barad S., Peleg Y., Albeck S., Dym O., Brandis A., Mehlman T. & Reich Z. (2022). The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.).  RSC Chemical Biology. 2022 Mar 9 , 3 (3):320-333.