Metabolic Profiling Publications

  1. Yirmiya E., Hobbs S. J., Leavitt A., Osterman I., Avraham C., Hochhauser D., Madhala B., Skovorodka M., Tan J. M., Toyoda H. C., Chebotar I., Itkin M., Malitsky S., Amitai G., Kranzusch P. J. & Sorek R. (2025). Structure-guided discovery of viral proteins that inhibit host immunity.  Cell. 2025 Mar 20 , 188 (6):1681-1692.e17.
  2. Yirmiya E., Hobbs S. J., Leavitt A., Osterman I., Avraham C., Hochhauser D., Madhala B., Skovorodka M., Tan J. M., Toyoda H. C., Chebotar I., Itkin M., Malitsky S., Amitai G., Kranzusch P. J. & Sorek R. (2025). Structure-guided discovery of viral proteins that inhibit host immunity.  Cell. 2025 Mar 20 , 188 (6):1681-1692.e17.
  3. Yossef Y. T. A., Peremen L. S., Telerman A., Goldinger G., Malitsky S., Itkin M., Halperin R., Yaloz N. P. & Tirosh A. (2025). Single-cell transcriptomics and metabolomic analysis reveal adenosine-derived metabolites over-representation in pseudohypoxic neuroendocrine tumours.  Clinical and Translational Medicine. 2025 Feb , 15 (2).
  4. Yossef Y. T. A., Peremen L. S., Telerman A., Goldinger G., Malitsky S., Itkin M., Halperin R., Yaloz N. P. & Tirosh A. (2025). Single-cell transcriptomics and metabolomic analysis reveal adenosine-derived metabolites over-representation in pseudohypoxic neuroendocrine tumours.  Clinical and Translational Medicine. 2025 Feb , 15 (2).
  5. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  6. Osterman I., Samra H., Rousset F., Loseva E., Itkin M., Malitsky S., Yirmiya E., Millman A. & Sorek R. (2024). Phages reconstitute NAD+ to counter bacterial immunity.  Nature. 2024 Oct 31 , 634 (8036):1160-1167.
  7. Osterman I., Samra H., Rousset F., Loseva E., Itkin M., Malitsky S., Yirmiya E., Millman A. & Sorek R. (2024). Phages reconstitute NAD+ to counter bacterial immunity.  Nature. 2024 Oct 31 , 634 (8036):1160-1167.
  8. Dong Y. & Malitsky S. (2024). MetaboReport: from metabolomics data analysis to comprehensive reporting.  Bioinformatics. 2024 Jun 1 , 40 (6).
  9. Sperfeld M., Narváez-Barragán D. A., Malitsky S., Frydman V., Yuda L., Rocha J. & Segev E. (2024). Algal methylated compounds shorten the lag phase of Phaeobacter inhibens bacteria.  Nature Microbiology. 2024 Aug , 9 (8):2006-2021.
  10. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  11. Eliason O., Malitsky S., Panizel I., Feldmesser E., Porat Z., Sperfeld M. & Segev E. (2024). The photo-protective role of vitamin D in the microalga Emiliania huxleyi.  iScience. 2024 Jun 21 , 27 (6).
  12. Eliason O., Malitsky S., Panizel I., Feldmesser E., Porat Z., Sperfeld M. & Segev E. (2024). The photo-protective role of vitamin D in the microalga Emiliania huxleyi.  iScience. 2024 Jun 21 , 27 (6).
  13. Vinik Y., Maimon A., Dubey V., Raj H., Abramovitch I., Malitsky S., Itkin M., Ma'ayan A., Westermann F., Gottlieb E., Ruppin E. & Lev S. (2024). Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy.  Advanced Science. 2024 Mar 5 , 11 (17).
  14. Vinik Y., Maimon A., Dubey V., Raj H., Abramovitch I., Malitsky S., Itkin M., Ma'ayan A., Westermann F., Gottlieb E., Ruppin E. & Lev S. (2024). Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy.  Advanced Science. 2024 Mar 5 , 11 (17).
  15. Bigelman E., Pasmanik-Chor M., Dassa B., Itkin M., Malitsky S., Dorot O., Pichinuk E., Kleinberg Y., Keren G. & Entin-Meer M. (2023). Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage.  PLoS ONE. 2023 Aug 24 , 18 (8).
  16. Kogan N. M., Begmatova D., Vinnikova L., Malitsky S., Itkin M., Sharon E., Klinov A., Gorelick J., Koman I., Vogel Z., Mechoulam R. & Pinhasov A. (2023). Endocannabinoid basis of personalityInsights from animal model of social behavior.  Frontiers in Pharmacology. 2023 Aug 16 , 14 .
  17. Cohen S., Itkin M., Faigenboim A., Davidovich-Rikanati R., Bar E., Hasson D., Shalev N., Koltai H., Sagee O., Lewinsohn E., Spitzer-Rimon B. & Schaffer A. A. (2023). Non-Aqueous Isolation and Enrichment of Glandular Capitate Stalked and Sessile Trichomes from Cannabis sativa.  Journal of Visualized Experiments. 2023 May , 2023 (195).
  18. Reddi R. N., Rogel A., Gabizon R., Rawale D. G., Harish B., Marom S., Tivon B., Arbel Y. S., Gurwicz N., Oren R., David K., Liu J., Duberstein S., Itkin M., Malitsky S., Barr H., Katz B., Herishanu Y., Shachar I., Shulman Z. & London N. (2023). Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.  Journal of the American Chemical Society. 2023 Feb 15 , 145 (6):3346-3360.
  19. Kshirsagar A., Doroshev S. M., Gorelik A., Olender T., Sapir T., Tsuboi D., Rosenhek-Goldian I., Malitsky S., Itkin M., Argoetti A., Mandel-Gutfreund Y., Cohen S. R., Hanna J. H., Ulitsky I., Kaibuchi K. & Reiner O. (2023). LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways.  Nature Communications. 2023 Jun , 14 (1).
  20. Kogan N. M., Begmatova D., Vinnikova L., Malitsky S., Itkin M., Sharon E., Klinov A., Gorelick J., Koman I., Vogel Z., Mechoulam R. & Pinhasov A. (2023). Endocannabinoid basis of personalityInsights from animal model of social behavior.  Frontiers in Pharmacology. 2023 Aug 16 , 14 .