Antibody Engineering Publications

  1. Miller S., Eizenberg-Magar I., Reich-Zeliger S., Rimer J., Zaretsky I., Reshef D., Kopitman E., Friedman N. & Antebi Y. E. (2025). Independent and temporally separated dynamics for RORγt and Foxp3 during Th17 differentiation.  Frontiers in Immunology. 2025 Apr 28 , 16 .
  2. Miller S., Eizenberg-Magar I., Reich-Zeliger S., Rimer J., Zaretsky I., Reshef D., Kopitman E., Friedman N. & Antebi Y. E. (2025). Independent and temporally separated dynamics for RORγt and Foxp3 during Th17 differentiation.  Frontiers in Immunology. 2025 Apr 28 , 16 .
  3. Tennenhouse A., Khmelnitsky L., Khalaila R., Yeshaya N., Noronha A., Lindzen M., Makowski E. K., Zaretsky I., Sirkis Y. F., Galon-Wolfenson Y., Tessier P. M., Abramson J., Yarden Y., Fass D. & Fleishman S. J. (2024). Computational optimization of antibody humanness and stability by systematic energy-based ranking.  Nature Biomedical Engineering. 2024 Jan , 8 (1):30-44.
  4. Khersonsky O., Goldsmith M., Zaretsky I., Hamer-Rogotner S., Dym O., Unger T., Yona M., Fridmann-Sirkis Y. & Fleishman S. J. (2023). Stable Mammalian Serum Albumins Designed for Bacterial Expression.  Journal of Molecular Biology. 2023 Sept 1 , 435 (17).
  5. Griess-Fishheimer S., Zaretsky J., Travinsky-Shmul T., Zaretsky I., Penn S., Shahar R. & Monsonego-Ornan E. (2022). Nutritional Approaches as a Treatment for Impaired Bone Growth and Quality Following the Consumption of Ultra-Processed Food.  International Journal of Molecular Sciences. 2022 Jan 1 , 23 (2).
  6. Mazor R. D., Nathan N., Gilboa A., Stoler-Barak L., Moss L., Solomonov I., Hanuna A., Divinsky Y., Shmueli M. D., Hezroni H., Zaretsky I., Mor M., Golani O., Sabah G., Jakobson-Setton A., Yanichkin N., Feinmesser M., Tsoref D., Salman L., Yeoshoua E., Peretz E., Erlich I., Mendelson Cohen N., Gershoni J. M., Freund N., Merbl Y., Yaari G., Eitan R., Sagi I. & Shulman Z. (2022). Tumor-reactive antibodies evolve from non-binding and autoreactive precursors.  Cell. 2022 Mar 31 , 185 (7):1208-1222.
  7. Biram A., Winter E., Denton A. E., Zaretsky I., Dassa B., Bemark M., Linterman M. A., Yaari G. & Shulman Z. (2020). B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.  Cell Reports. 2020 Feb 11 , 30 (6):1910-1922.
  8. McBride R. D., Stygar W. A., Cuneo M. E., Sinars D. B., Mazarakis M. G., Leckbee J. J., Savage M. E., Hutsel B. T., Douglass J. D., Kiefer M. L., Oliver B. V., Laity G. R., Gomez M. R., Yager-Elorriaga D. A., Patel S. G., Kovalchuk B. M., Kim A. A., Gourdain P. -., Bland S. N., Portillo S., Bott-Suzuki S. C., Beg F. N., Maron Y., Spielman R. B., Rose D. V., Welch D. R., Zier J. C., Schumer J. W., Greenly J. B., Covington A. M., Steiner A. M., Campbell P. C., Miller S. M., Woolstrum J. M., Ramey N. B., Shah A. P., Sporer B. J., Jordan N. M., Lau Y. Y. & Gilgenbach R. M. (2018). A Primer on Pulsed Power and Linear Transformer Drivers for High Energy Density Physics Applications.  IEEE Transactions on Plasma Science. 2018 Nov 7 , 46 (11):3928-3967.
  9. Polonsky M., Rimer J., Kern-Perets A., Zaretsky I., Miller S., Bornstein C., David E., Kopelman N. M., Stelzer G., Porat Z., Chain B. & Friedman N. (2018). Induction of CD4 T cell memory by local cellular collectivity.  Science. 2018 Jun 15 , 360 (6394).
  10. Polonsky M., Rimer J., Kern-Perets A., Zaretsky I., Miller S., Bornstein C., David E., Kopelman N. M., Stelzer G., Porat Z., Chain B. & Friedman N. (2018). Induction of CD4 T cell memory by local cellular collectivity.  Science. 2018 Jun 15 , 360 (6394).
  11. Adutler-Lieber S., Zaretsky I., Sabany H., Kartvelishvily E., Golani O., Geiger B. & Friedman N. (2017). Substrate-bound CCL21 and ICAM1 combined with soluble IL-6 collectively augment the expansion of antigen-specific murine CD41 T cells.  Blood advances. 2017 Jun 27 , 1 (15):1016-1030.
  12. Madi A., Poran A., Shifrut E., Reich-Zeliger S., Greenstein E., Zaretsky I., Arnon T., Van Laethem L. F., Singer A., Lu J., Sun P. D., Cohen I. R. & Friedman N. (2017). T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences.  eLife. 2017 Jul 21 , 6 .
  13. Zaretsky I., Atrakchi O., Mazor R. D., Stoler-Barak L., Biram A., Feigelson S. W., Gitlin A. D., Engelhardt B. & Shulman Z. (2017). ICAMs support B cell interactions with T follicular helper cells and promote clonal selection.  Journal of Experimental Medicine. 2017 Nov 1 , 214 (11):3435-3448.
  14. Eizenberg-Magar I., Rimer J., Zaretsky I., Lara-Astiaso D., Reich-Zeliger S. & Friedman N. (2017). Diverse continuum of CD4+ T-cell states is determined by hierarchical additive integration of cytokine signals.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug 1 , 114 (31):E6447-E6456.
  15. Yosef R., Pilpel N., Papismadov N., Gal H., Ovadya Y., Vadai E., Miller S., Porat Z., Ben-Dor S. & Krizhanovsky V. (2017). p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling.  EMBO Journal. 2017 Aug 1 , 36 (15):2280-2295.
  16. Adutler-Lieber S., Zaretsky I., Platzman I., Deeg J., Friedman N., Spatz J. P. & Geiger B. (2014). Engineering of synthetic cellular microenvironments: Implications for immunity.  Journal of Autoimmunity. 2014 Nov 1 , 54 :100-111.
  17. Hart Y., Reich-Zeliger S., Antebi Y. E., Zaretsky I., Mayo A. E., Alon U. & Friedman N. (2014). Paradoxical signaling by a secreted molecule leads to homeostasis of cell levels.  Cell. 2014 Aug 28 , 158 (5):1022-1032.
  18. Jaitin D. A., Kenigsberg E., Keren-Shaul H., Elefant N., Paul F., Zaretsky I., Mildner A., Cohen N., Jung S., Tanay A. & Amit I. (2014). Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types.  Science. 2014, 343 (6172):776-779.
  19. Lara Astiaso A. D., Weiner A., Lorenzo Vivas V. E., Zaretsky I., Jaitin D. A., David E., Keren-Shaul H., Mildner A., Winter D., Jung S., Friedman N. & Amit I. (2014). Chromatin state dynamics during blood formation.  Science. 2014 Aug 22 , 345 (6199):943-949.
  20. Polonsky M., Zaretsky I. & Friedman N. (2013). Dynamic single-cellmeasurements of gene expression in primary lymphocytes: Challenges, tools and prospects.  Briefings in Functional Genomics. 2013 Mar , 12 (2):99-108.