Crystallization, Structural Determination and Structure Modeling Publications

  1. Graslund S., Peleg Y., Albeck S., Unger T., Dym O., Prilusky J. & Sussman J. L. (2008). Protein production and purification.  Nature Methods. 2008 Feb , 5 (2):135-146.
  2. Goihberg E., Dym O., Tel-Or S., Shimon L., Frolow F., Peretz M. & Burstein Y. (2008). Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.  Proteins-Structure Function And Bioinformatics. 2008 Aug 1 , 72 (2):711-719.
  3. Röthlisberger D., Khersonsky O., Wollacott A. M., Jiang L., DeChancie J., Betker J., Gallaher J. L., Althoff E. A., Zanghellini A., Dym O., Albeck S., Houk K. N., Tawfik D. S. & Baker D. (2008). Kemp elimination catalysts by computational enzyme design.  Nature. 2008 May 8 , 453 (7192):190-195.
  4. Reichmann D., Cohen M., Abramovich R., Dym O., Lim D., Strynadka N. C. J. & Schreiber G. (2007). Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.  Journal of Molecular Biology. 2007 Jan 19 , 365 (3):663-679.
  5. Shaaltiel Y., Bartfeld D., Hashmueli S., Baum G., Brill-Almon E., Galili G., Dym O., Boldin-Adamsky S. A., Silman I., Sussman J. L., Futerman A. H. & Aviezer D. (2007). Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.  Plant Biotechnology Journal. 2007 Sept , 5 (5):579-590.
  6. Goihberg E., Dym O., Tel-Or S., Levin I., Peretz M. & Burstein Y. (2007). A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase.  Proteins-Structure Function And Bioinformatics. 2007 Jan 1 , 66 (1):196-204.
  7. Berry I. M., Dym O., Esnouf R. M., Harlos K., Meged R., Perrakis A., Sussman J., Walter T. S., Wilson J. & Messerschmidt A. (2006). SPINE high-throughput crystallization, crystal imaging and recognition techniques: Current state, performance analysis, new technologies and future aspects.  Acta Crystallographica Section D: Biological Crystallography. 2006 Oct , 62 (10):1137-1149.
  8. Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N. (2006). Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.  Acta Crystallographica Section D: Biological Crystallography. 2006 Oct , 62 (10):1196-1207.
  9. Asher G., Dym O., Tsvetkov P., Adler J. & Shaul Y. (2006). The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.  Biochemistry. 2006 May 23 , 45 (20):6372-6378.
  10. Albeck S., Alzari P., Andreini C., Banci L., Berry I. M., Bertini I., Cambillau C., Canard B., Carter L., Cohen S. X., Diprose J. M., Dym O., Esnouf R. M., Felder C., Ferron F., Guillemot F., Hamer R., Ben Jelloul J. M., Laskowski R. A., Laurent T., Longhi S., Lopez R., Luchinat C., Malet H., Mochel T., Morris R. J., Moulinier L., Oinn T., Pajon A., Peleg Y., Perrakis A., Poch O., Prilusky J., Rachedi A., Ripp R., Rosato A., Silman I., Stuart D. I., Sussman J., Thierry J. -., Thompson J. D., Thornton J. M., Unger T., Vaughan B., Vranken W., Watson J. D., Whamond G. & Henrick K. (2006). SPINE bioinformatics and data-management aspects of high-throughput structural biology.  ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY. 2006 Oct , 62 (10):1184-1195.
  11. Albeck S., Burstein Y., Dym O., Jacobovitch Y., Levi N., Meged R., Michael Y., Peleg Y., Prilusky J., Schreiber G., Silman I., Unger T. & Sussman J. (2005). Three-dimensional structure determination of proteins related to human health in their functional context at the Israel Structural Proteomics Center (ISPC).  Acta Crystallographica Section D: Biological Crystallography. 2005 Oct , 61 (10):1364-1372.
  12. Reichmann D., Rahat O., Albeck S., Meged R., Dym O. & Schreiber G. (2005). The modular architecture of protein-protein binding interfaces.  Proceedings of the National Academy of Sciences of the United States of America. 2005 Jan , 102 (1):57-62.
  13. Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A. (2002). Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.  Journal of Biological Chemistry. 2002 Nov 29 , 277 (48):46304-46309.
  14. Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U. (1996). Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.  Thrombosis and Haemostasis. 1996, 76 (3):283-291.
  15. Dym O., Mevarech M. & Sussman J. L. (1995). Structural features that stabilize halophilic malate dehydrogenase from an archaebacterium.  Science. 1995 Mar 3 , 267 (5202):1344-1346.