Department of Biomolecular Sciences
Postdoc position
We are looking for a postdoctoral fellow to work on a new and exciting project on lipid complexity. There are many more lipids in cells and in cell membranes than once thought and this complexity has significant ramifications for understanding both the roles of lipids in the origin of life and also in modern cell function. A position is available for an enthusiastic candidate to work on lipids in the origin of life, lipid fine-tuning, and functional studies of lipid complexity. For publications and details see the lab web page at
https://www.weizmann.ac.il/Biomolecular_Sciences/Futerman/
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Department of Molecular Cell Biology
Postdoc position
We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing"
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We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing" at Weizmann Institute. The project is a collaboration of laboratories of Uri Alon, Tali Kimchi and Valery Krizhanovsky. It will combine cutting edge methods in molecular and cellular biology, behavioral neuroscience and system biology in mouse models. An expertise in behavioral neuroscience, molecular biology and mouse models is a plus.
Department of Immunology and Regenerative Biology
Postdoc position
Emergence of resistance to anti-cancer drugs currently limits the application of relatively specific new drugs. We are interested in resolving the underlying mechanisms and, accordingly, offer novel combinations of drugs.
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Adaptive changes enable cancer cells to evade the apoptosis-inducing effects of anti-cancer drugs. We are interested in kinase inhibitors and monoclonal anti-tumor antibodies, which are often highly effective initially, but frequently loose activity due to adaptations and emergence of new mutations. Once the underlying mechanisms of drug resistance are resolved a new drug combination might be offered. The emergence of new mutations is driven by mutators that interfere with the normal function of the DNA replication fork, which is the focus of our studies. Similarly, we are interested in checkpoint inhibitors, such as PD-L1, the underlying oncogenic effects and ways to enhance responses to checkpoint inhibitors.
Department of Molecular Genetics
Postdoc position
The Laufman lab studies the ways human RNA viruses interact with their host cells and transform them into viral manufactories using cutting-edge microscopy, molecular and cell biology, genetic and biochemistry approaches. We tackle questions at the forefront of the exciting field of virology. We are looking for talented and highly motivated postdocs to join our team. If you possess a strong background in molecular biology and the passion to execute a groundbreaking research – your place is with us! We are located in the heart of the vibrant campus of the Weizmann Institute of Science, with state-of-the-art research facilities and a variety of supportive services such as recreation center, infants’ daycare, lawns and sport fields and much more.
Department of Immunology and Regenerative Biology
Postdoc position
The objective of this study is to better understand the state and severity of infection during pregnancy and its effect on fetal development and neonatal outcome.
Department of Molecular Genetics
Postdoc position
Intracellular and intercellular RNA trafficking
Department of Molecular Cell Biology
Postdoc position
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Ferroptosis is a newly discovered cell death pathway driven by iron-dependent lipid peroxidation. We recently discovered new inducers of ferroptosis, and specific metabolic states that increase vulnerability to ferroptosis, and thus can be used for cancer therapy. We have multidisciplinary projects related to ferroptosis in TNBC, and we are currently looking for two talented and enthusiastic postdocs to join us.
Department of Molecular Cell Biology
Postdoc position
Combination therapies for TNBC
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Triple negative breast cancer (TNBC) is a highly aggressive disease that affects young women and currently has no effective treatment. The goal of our studies is to identify new therapeutic strategies for this particular subtype of breast cancer. Synthetic lethality is a powerful approach to selectively eliminate vulnerable cancer cells, and thus can be exploited for cancer therapy. Many studies including our own indicate that synthetic lethality screens could be a promising approach to identify novel drug targets for TNBC. A postdoctoral position is available to establish a genome-wide synthetic lethal screen to identify potent combination therapies for TNBC subtypes.
Department of Biomolecular Sciences
Postdoc position
Molecular signaling in control of immune defense: regulation of programmed cell death and signaling for gene activation.
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Motivated and creative students with background in molecular biology are invited to join our studies of the mechanisms by which signaling by the TNF family contributes to immune defense, to chronic inflammatory and autoimmune diseases and to cancer, and our attempts to derive from this knowledge new ways of therapy. See our website and list of publications for the range of research subjects that we are exploring and for the range of experimental approaches that we are applying. (https://www.weizmann.ac.il/Biomolecular_Sciences/Wallach/home)
Department of Chemical and Biological Physics
Postdoc position
Positions are for development of lower bounds to energies which compete with the Ritz variational method in accuracy. They are for one year with option of renewal for another year. For more information visit my website: http://www.weizmann.ac.il/chemphys/pollak/positions
Department of Biomolecular Sciences
Postdoc position
Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous.
This is a full-time position available from June 2022 for a period of three years with a possibility of a further extension subject to funding availability.
Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki.
For any informal inquiries please contact us by email at
neta.regev-rudzki@weizmann.ac.il
Department of Condensed Matter Physics
Postdoc position
Our lab investigates quantum phenomena which focus on the interplay between correlations and topology. This intriguing interplay allows to develop unique realizations of non-abelian quasi-particles (qps) which are neither Boson nor Fermion-like. Among the phases which host these qps are the well-known fractional quantum Hall effect, topological superconductivity, and the recently emerging field of moire-superlattcies (twistronics). We are developing experiments in these arrowheads to unravel this intriguing physics.
This line of research often utilizes quantum materials whose reduced dimensionality enhances quantum effects. We profit from the use of various van der Waals (vdW) materials (graphene, hBN, TMDs, etc.) as well as high-mobility two-dimensional GaAs electron gas, which are both grown in our department. Fabrication is performed in a state-of-the-art clean room facility, specially designed for vdW materials nanofabrication.
These devices will be measured with transport techniques including quantum Hall interferometry, Josephson interferometry, capacitance measurements, thermal transport, and shot noise measurements. These measurements require high magnetic fields and low electron temperatures. Our lab will be equipped with an 8mK wet dilution refrigerator with a 20T magnet, a 7mK dry dilution with a 3D vector magnet, as well as a variable temperature cryostat.
Funding is available for three years. Advantage for prior experience with: vdW materials, fabrication techniques, transport measurements and cryogenic systems.
Interested candidates should send CV and list of publications to yuval.ronen@weizmann.ac.il
Department of Chemical and Biological Physics
Postdoc position
Postdoc in theoretical biological physics of cells - including mesoscale structure and dynamics of the cytoplasm and of the nucleus. Most projects are in collaboration with experimental partners. Strong background in statistical physics and soft matter physics is very useful. For examples of our research and publications see: https://www.weizmann.ac.il/chembiophys/SafranGroup/
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The Safran group focuses on theoretical studies of the structure, phase behavior and dynamics of biological cells and their relation to the soft matter, physical properties of membranes, macromolecules, and colloids, using the approaches of coarse-grained, statistical thermodynamics and dynamics. Through our interactions with experimental groups, the theory is applied to problems such as: cell volume determination, phase separation and chromatin organization at the nuclear scale, and spontaneous oscillations of cardiomyocytes.
Department of Biomolecular Sciences
Postdoc position
Membrane protein folding and quality control
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Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. For more details, visit http://www.weizmann.ac.il/Biomolecular_Sciences/Fluman
Department of Physics of Complex Systems
Postdoc position
Study of dynamics of viscoelastic straight channel flow, the role of inertial effect on its properties, and possible relation between elastic and elasto-inertial turbulence.
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Funding is available for three years. Contract is for one year, and will be renewed with good progress. The candidate should have a demonstrated potential for excellence in research. Advantage for background in experimental hydrodynamics, experience in particle image velocimetry (PIV), programming and computationally intensive data analysis. Knowledge and experience to characterize polymer solution is desirable. Interested candidates should send CV and list of publications to victor.steinberg@weizmann.ac.il
Department of Particle Physics and Astrophysics
Postdoc position
We live in fortunate times, where there are still many fundamental unsolved problems in astrophysics, while technological progress allows new observations, which may make some of them solvable. Now is the time to attack the most puzzling challenges posed to us by the Universe.
Join Doron Kushnir's group to study explosions and extreme stars of the Universe. We use theoretical and computational tools to interpret state-of-the-art observations, aiming at resolving fundamental problems in astrophysics.
Department of Systems Immunology
Postdoc position
a brand-new lab at the Systems Immunology department looking to recruit the first generation of lab members!
Our focus is on understanding the cellular networks that control both inflammatory and peaceful immune responses. We develop cutting-edge technologies and combine them with classical immunology techniques, along with mouse genetics, to investigate communication between T cells and various types of antigen-presenting cells.
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As living creatures, we are continually interacting with our surroundings and our immune system is required to distinguish non-harmful entities from dangerous intruders and react accordingly. CD4 T cells are activated by different antigen presenting cell (APC) and acquire alternative cell fates to mediate distinct immune responses. Antigen presentation also allows activated T cells to act and instruct specific antigen presenters. Thus, antigen presentation is the beating heart of adaptive immunity, allowing ongoing cross-talk between multiple cell types to achieve immunity and tissue adaptation.
?Which APCs instruct T cells? Which APCs are instructed by T cells?
?While tools to allow monitoring of specific T cell responses were invented 20 years ago and revolutionized our understanding of adaptive immunity, identifying which APC presents specific peptides, at the single cell level is still out of reach.
We will combine an engineering approach and biochemistry with single-cell RNA sequencing technologies, to develop a method for detecting specific antigen presenters. We believe that this technology along with classical immunology, will enable us to address fundamental questions in the field of antigen presentation.
Department of Brain Sciences
Postdoc position
We study the genetic and cellular mechanisms through which sensory and emotional experiences alter information processing in neural circuits. Our research is highly interdisciplinary and combines genomic, molecular, histological, electrophysiological, in vivo imaging and behavioral techniques into an integrative Molecular Systems Neuroscience approach.
We seek to recruit Ph.D. students for the following projects:
- Molecular properties of functionally defined neurons in the cortex - the project combines in vivo GCaMP imaging & photo-labelling, advanced sequences methods and spatial transcriptomics.
- Genetic and cellular mechanisms through which schizophrenia-associated interneurons regulate the plasticity of cortical circuits.
- The genetic basis of representational stability in the cortex.
- Genes & transcriptional mechanisms in GABAergic interneurons that restrict plasticity in cortical circuits.
- Subcellular genetic mechanisms that integrate sensory and contextual/emotional information in neurons.
Department of Immunology and Regenerative Biology
Postdoc position
Experimental and computational approaches for studying the biology of long RNAs.
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We are interested in understanding what kind of activities can long RNAs, including both long noncoding RNAs (lncRNAs) and mRNAs, or fragments thereof, carry out in mammalian cells. We particularly interested in the question of how these activities are encoded in the genomic sequences of these genes, how they are related to the secondary structures they adopt in cells, how mutations in lncRNA genes or in noncoding regions in mRNA UTRs affect their function, and how to exploit all this knowledge to design better therapeutic approaches for both rare and common diseases. We are addressing these questions using a combination of both experimental biology (including molecular biology, cell biology, stem cell biology, and neurobiology) and computational biology/bioinformatics. Postdoctoral positions focused on specific projects related to these questions are available.
Department of Biomolecular Sciences
Postdoc position
Size and growth control in neurons and other large cells - do cells sense their own size and how can they do that?
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Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Department of Plant and Environmental Sciences
Postdoc position
We are looking for extremely talented candidates to use and develop state-of-the-art cryo electron microscopy techniques for the study of cellular mineralization.
Department of Biomolecular Sciences
Postdoc position
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Circadian clock resetting and Chrono-medicine
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How the clock integrates different resetting cues? Are there differences in resetting capacity between different cell types? How different pharmaceutics influence the clock? Can it be harnessed to improve therapy?
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- Clocks resetting | Recently, we have developed a new method to study resetting agents in vitro in an efficient and high-throughput manner, dubbed Circa-SCOPE (Manella et al., Nature Communication 2021). This methodology opens the door to a wide range of applications, in both basic and translational research. For example, it allows screening multiple drugs (in-use or newly developed) in parallel to identify which affects the clock and how – with high relevance to chrono-medicine. It also allows the experimental testing of different models of clock resetting quantitatively. Hence, it opens the door to a wide range of basic and translational research opportunities.
Department of Biomolecular Sciences
Postdoc position
- Circadian exercise
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In the past 7 years, we studied the cross-talk between metabolism and circadian rhythms, leading us to venture into other fields, like exercise biology. Some exciting questions, both related to physiology and molecular mechanism, that stem from our recent publications (Adamovich et al., Proc. Natl. Acad. Sci. USA, 2021; Ezagouri et al., Cell Metabolism, 2019) are now under investigation.
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The relevant projects address the influence of circadian clocks on exercise performance, and training efficiency, as well as the effect of chronotype, feeding, and hypoxia on exercise capacity.
Circadian clocks are key regulators of daily physiology and metabolism in mammals. Our understanding of the role of the circadian clock and specific clock proteins in controlling exercise capacity is rudimentary. Consequently, there is growing interest in exercise biology in general, specifically in its interaction with other processes that govern whole-body physiology and metabolism. We have reported that mice show a day-time variance in exercise capacity, and it is affected by exercise intensity and clock proteins and elicits a distinct muscle transcriptomic and metabolic signature. Specifically, we demonstrated that ZMP, an AMPK activator, is induced by exercise in a daytime-dependent manner. We continue to study various aspects of exercise physiology through the lens of circadian biology (Ezagouri et al., Cell Metabolism, 2019; Adamovich et al., Proc. Natl. Acad. Sci., 2021.).
We employ various clock mutant mouse models with different light regimens to characterize the interaction between clocks and exercise. Further, we have designed and built fully automated time-controlled Running Wheels that can be programmed in advance to be in locked or unlocked positions for designated times to enable scheduled training of animals without manual interventions. This experimental setup is optimized for addressing questions regarding the involvement of daytime and circadian clocks in regulating exercise capacity (Adamovich et al., STAR Protocols, 2021).
We are also studying the molecular clock and skeletal muscle metabolism in health and disease.
Department of Chemical and Biological Physics
Postdoc position
Studies of transition times in quantum and classical mechanics. We want to answer the question how long does it take to make a quantum transition. We are also interested in classical transition times for protein folding and the information they give. For further details see our recent publications and visit my website.
Department of Physics of Complex Systems
Postdoc position
Our lab tries to bring molecules into the forefront of quantum technologies. We have open postdoc positions for leading and developing state-of-the-art quantum systems based on molecules.
For more information on our lab, visit: https://www.weizmann.ac.il/complex/meir/
Candidates should send their CV, list of publications, and a brief summary of their relevant scientific skills and achievements so far to ziv.meir@weizmann.ac.il
Department of Condensed Matter Physics
Postdoc position
Scanning probe microscopy of quantum and topological states of matter
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Study of quantum and topological states of matter using novel scanning probe microscopy tools. We have recently developed a nano-SQUID (Superconducting Quantum Interference Device) that resides on a very sharp tip and allows imaging of local magnetic fields with single electron spin sensitivity and of current flow patterns. This device provides also a unique tool for cryogenic thermal imaging with 1 ֲµK sensitivity and scanning gate microscopy allowing imaging electron scattering and dissipation mechanisms on the nanoscale. The project will focus on utilizing these novel techniques for microscopic investigation of topological and quantum states of matter including investigation of local topology, superconductivity, magnetism, strongly correlated electronic states, and dissipation in graphene, moiré superlattices, and van der Waals heterostructures.
Department of Physics of Complex Systems
Postdoc position
Experimental/Theory on application of laser plasma accelerator to radiotherapy
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The use of very high energy electron (250 MeV) as the one we currently produce at WIS, has been shown to improve cancer treatment. The aims of the work is to scale down the apparatus by optimising all the process in order to deliver such VHEE beam with a machine that has to be competitive with conventional RT machine and with a compact size.
Department of Physics of Complex Systems
Postdoc position
Our research centers on the theory of complex systems and biophysics, applied to a broad spectrum of problems, mainly in the context of the physics of living systems. Our research is often done in collaboration with experimental groups. Key themes of our lab include mathematical modeling of cell growth and mechanics, both at the single-cell level and the population level, stochastic processes, disordered systems, and coarse-grained modeling of complex processes.
For more information and recent publications see: https://amir.seas.harvard.edu/
Department of Condensed Matter Physics
Postdoc position
Synthesis, fabrication, and study of van der Waals single crystals and heterostructures
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There are two classes of quantum materials that take the condensed matter community by storm, topological materials, and van der Waals heterostructures. In these systems specific electronic band structures, magnetic properties, and confinement of electrons to two dimensions lead to new states of matter with huge potential for future applications. Our group specializes in the synthesis and in-depth study of these materials, using the facilities of our recently established quantum materials laboratory. The project focuses on transition metal dichalcogenides, which are a rich playground for new types of topology protected surface states in bulk crystals, as well as important building blocks for van der Waals heterostructures when exfoliated down to few-layer or monolayer crystal sheets. The candidate will engage in synthesis and detailed experimental study of high purity single crystals, develop advanced synthesis methods, and closely collaborate with our ab-initio materials simulation group, as well as our nano-probe microscopy groups. Our infrastructure offers a wide range of facilities for chemical, structural and physical property analysis, and state-of-the-art tools for device fabrication. Synchrotron x-ray scattering at international facilities, high pressure experiments, and involvement in nano-probe microscopy experiments are further options, depending on background and inclination. The candidate should have extensive experience in materials synthesis and characterization, device fabrication, and the physics of topological materials or van der Waals heterostructures. The initial contract is for one year with possibility of extension up to three years pending on progress. Interested candidates should send a CV and list of publications to markus.huecker@weizmann.ac.il.
Department of Condensed Matter Physics
Postdoc position
Development of novel types of superconducting qubits and their use in quantum computation and simulation.
Department of Physics of Complex Systems
Postdoc position
Experimental study of the ecology of bacterial communities from a 700 million year old site
Department of Immunology and Regenerative Biology
Postdoc position
Genetically encoded metal transporters in pregnancy
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Development of novel genetically encoded metal binding proteins for targeted imaging and therapy.
This study will extend our research on ferritin as a reporter gene for MRI:
https://www.weizmann.ac.il/dept/irb/neeman/research-activities/protocols-reporter-genes-and-probes-molecular-imaging
Department of Molecular Cell Biology
Postdoc position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
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Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Chemical and Structural Biology
Postdoc position
Talented and motivated individual who wishes to study the mechanism of GroEL-assisted folding using molecular biology and biophysical approaches
Department of Biomolecular Sciences
Postdoc position
We are inviting students interested in evolution, microbial communities, gene-phenotype relations and their interaction with past and current environments to join us.
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Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model.
Department of Condensed Matter Physics
Postdoc position
Development of novel types of superconducting qubits and their use in quantum computation and simulation.
Department of Biomolecular Sciences
Postdoc position
We are looking for skilled and motivated postdocs to lead a project on gene amplification evolution in cancer. This project requires knowledge in experimental biology, microscopy and image analysis, and a variety of sequencing methodologies.
The candidate should have experience in cell culture work, molecular biology, and microscopy.
Expertise in bioinformatic analyses of DNA and RNA sequencing is a big advantage.
Our lab studies how catastrophic numerical and structural chromosome aberrations are formed in cancer. Such chromosome defects are found in the majority of human tumors and are strong drivers of cancer initiation, growth, metastasis, and therapy resistance. By understanding the underlying mechanisms of chromosome alterations, we aim to identify targetable vulnerabilities to be used for novel therapy design.
For more details, please contact Ofer: ofer.shoshani@weizmann.ac.il
Department of Condensed Matter Physics
Postdoc position
Post doc position opening in the semiconductor nanowires, molecular beam epitaxy growth laboratory of the Department of Condensed Matter Physics. The research focuses on advanced nanowire materials and structures for quantum research studies. The studies include growth and characterization by SEM, TEM and EDAX in close collaboration with the STM group of Prof Haim Beidenkopf.
Dr. Hadas Shtrikman
Department of Condensed matter Physics
Hadas.shtrikman@Weizmann.ac.il
Department of Chemical and Biological Physics
Postdoc position
Scientists with interest in working with magnetic resonance are sought for the development of new metabolic imaging experiments. The student will work on understanding the physics and performing an array of new MRI experiments on high end scanners, and apply these in the detection of small tumors, and in the evaluation of chemotherapeutic and biological treatments. The student will be advised by physicists, chemists and biologists/clinicians in this project
Department of Chemical and Biological Physics
Postdoc position
Scientists are being sought for developing new experiments in the area of electron-enhanced nuclear magnetic resonance. This so-called dynamic nuclear polarization (DNP) NMR experiment subjects electrons in the sample to microwave irradiation, and then uses the ensuing nuclear polarization enhancement to open new analytical and metabolic frontiers in NMR. Topics involved in this research will include developing new forms of quantum control between spins to enable a more efficient electron-->nuclear polarization transfer, automation, cryogenics, and the design and construction of radiofrequency and microwave components. Programming experience also required. Applications of this project to solve both analytical and biophysical problems are also envisioned.
Department of Biomolecular Sciences
Postdoc position
We have open positions for Ph.D. candidates interested in mechanisms of channel regulation by GPCRs using, but not limited to, computational (molecular dynamics), electrophysiological, molecular and/or optical methodologies.
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G protein-coupled receptors (GPCRs) are the largest gene family in the human genome. Their role is to translate chemical information into cellular responses, like olfactory processing, neuronal activity modulation, and hormone actions or regulating blood pressure among many. Their cellular effectors can range from various enzymes to ion channels. Interestingly, nature has designed the GPCR as a major target for many natural compounds and the pharmaceutical industry has focused its attention on designing various agonists and antagonists to treat various illnesses. In the lab, we focus on the regulation of ion channels by GPCRs with the main focus on the regulation of potassium channels. This form of regulation comprises one of the major mechanisms in controlling slow synaptic inhibition in the brain, a process when compromised leads to seizures ataxia, and many other neuronal abnormalities.
The lab's interests span from a molecular understanding of channel regulating mechanisms at the single molecule level to animal behavior using various electrophysiological, molecular, imaging, and computational tools.
We seek highly motivated students to join us in this very exciting scientific journey.
Department of Biomolecular Sciences
Postdoc position
The goal of our research is to understand how pancreatic beta cells perform their unique functions. Beta cells are the only cell in the body capable of significant production of insulin. They store insulin intracellularly, releasing it to the bloodstream in response to a variety of physiological stimuli including nutrients such as glucose and fatty acids, hormones and neurotransmitters.
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In our research, we focus on the following aspects of beta cell function:
- The transcriptional mechanisms underlying the normal embryonic development of beta cells and the functioning of mature beta cells
- Manipulating pancreatic cellular identity: molecular mechanisms controlling exocrine to endocrine cell reprogramming
- Dissecting the signaling mechanism that permit beta cells to respond to modulators of insulin secretion, in particular long chain and short chain fatty acids
See:
https://www.weizmann.ac.il/Biomolecular_Sciences/Walker/
Department of Molecular Cell Biology
Postdoc position
Dissecting metabolic changes that accompany carcinogenesis at the tumor, microenvironment and host levels for improving cancer diagnosis and therapy.
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Starting from a clinically relevant question we follow the metabolic changes that occur along cancer disease course. Identifying such changes enables us to optimize early cancer diagnosis and to intervene therapeutically.
Department of Plant and Environmental Sciences
Postdoc position
The Vardi lab is seeking highly skilled and motivated candidates with expertise in metabolomics to join a new and exciting project funded by the ERC in the field of chemical ecology, focusing on chemical communication during tripartite symbiotic and pathogenic interactions in the ocean. We aim to unravel the metabolic crosstalk between algae, viruses, and the associated microbiome, which has major ecological consequences on cell fate of algal blooms in the ocean.
Our laboratory employs state-of-the-art mass spectrometry, including high resolution LC-MS and GC-MS to investigate the metabolic dynamics of microbial interactions at sea.
The project will involve diverse analytical chemistry tools, such as:
- Targeted metabolomics and lipidomics
- Non-targeted metabolic profiling and fingerprinting
- de novo identification of novel metabolites
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of neutral atom quantum simulators
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In collaboration with Ofer Firstenberg recently started a new joint project on efficient coupling of neutral-atom tweezer arrays to light. On the theoretical side we are collaborating with Efi Shahmoon. We plan to extend Efi’s original ideas for strong coupling in atomic arrays in sub-wavelength optical lattices (recently verified experimentally by Immanuel Bloch) to the emerging and promising field of quantum simulators with Rydberg atoms in tweezer arrays, where the spacing between the atoms is larger than the wavelength. The challenge to achieved strong coupling to light in such large-spacing arrays emerges from the existence of many diffraction orders that cannot be controlled.
Our proposed scheme to overcome this challenge is based on two supplementary efforts: first we will reduce the spacing between neighboring atoms in the array to <1.5 microns, by suppressing the mutual interferences that limit this distance to >3 microns in most state of the art demonstrations. Such spacing reduction will reduce the non-vanishing diffraction orders from the periodic array from many tens to only few. Next we will incorporate the tweezer array inside a medium finesse optical cavity that will enhance the zero diffraction order as compared to the others so as to ensure strong coupling to it.
We plan to achieve strong coupling to light, show efficient transfer of coherence and quantum states from the array onto a single radiation mode and then use it to demonstrate and study novel schemes for quantum simulators within the atomic tweezer array as well as quantum coupling between tweezer arrays for “scalable” quantum computer based on Rydberg induced gates.
Department of Particle Physics and Astrophysics
Postdoc position
Postdoctoral work on data from SoXS, a new spectrograph with novel capabilities
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I am looking for a postdoc interested in leading the work here at Weizmann on data from the new SoXS instrument, a very efficient, broad-band and high resolution spectrograph to be commissioned on the 3.6m NTT telescope in Chile in the coming year. The unique capabilities of this instrument open up new windows for discovery, and Weizmann is a leading institution in the consortium building and operating this instrument.
Department of Earth and Planetary Sciences
Postdoc position
Investigation the biological and toxicological effects of SOA from on-road car emissions funded by the EU
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Description and lab research areas:
Our lab studies the health impacts of air pollution, the number one environmental cause of the global disease burden. This newly funded EU project ( ASVOLEE, Effects on Air quality of Semi-VOLatile Engine Emissions) involves studying cytotoxicity imposed by exposure to SOA particles formed from on-road cars under real driving conditions.
The project will use cultured cell models, together with big data analysis such as toxicology, RNA sequencing, and metabolomics analyses. Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. Through this new EU project, we will offer a dynamic and international collaboration between the Weizmann Institute of Science and other key laboratories in Europe. The work involves active collaborations between the participating groups and taking active roles in joint experimental campaigns, data analyses, paper writing, and weekly joint seminars, among other activities.
The target of this PhD/Post Doc research focuses on investigating the mechanisms (biological and toxicological effects) induced by collected SOA in field campaigns with advanced exposure models. In vitro exposure will focus on optimizing exposure of human epithelial lung cells and other tissue (liver, fat) cultures and developing differentiated 3D cell cultures and disease-oriented tissue models.
Required elements for research-based postdoc applications: Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. PhD in Chemistry, Biology, Biochemistry, Atmospheric sciences, or related fields.
Please send applications to Prof. Yinon Rudich, Department of Earth and Planetary Sciences, Weizmann Institute, Rehovot 76100, Israel
e-mail: yinon.rudich@weizmann.ac.il, Tel: 972 8 934 4237
Lab website: https://www.weizmann.ac.il/EPS/Rudich/
Department of Particle Physics and Astrophysics
Postdoc position
Plasma Physics, Spectroscopy, Plasma Diagnostics, Atomic Physics
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We study processes in plasmas subjected to high-energy deposition: conversion of electric energy to heat and radiation, turbulence, fast penetration of magnetic fields into plasmas, and plasma rotation. For diagnosing the plasma we develop fast, high-resolution spectroscopy of radiation in the visible, U.V., vacuum UV, and x-ray regions. We have close collaboration with major universities and institutions in the US and Europe.
Department of Earth and Planetary Sciences
Postdoc position
Investigating the atmospheric chemistry of organic aerosol aging, physical properties, and potential health effects
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Aerosols participate in many environmental processes affecting the climate, human health and ecosystems. The qualified candidate will work on topics related to organic aerosol aging, physical properties, and potential health effects. Our research efforts focus on: a) understanding the origin, molecular composition, atmospheric transformations, and optical properties of light-absorbing organic aerosols (anthropogenic, biogenic, urban, and biomass burning SOA), and b) connecting aerosol composition, its changes, and the resulting health effects. Some relevant papers:
Required elements for research-based postdoc applications
Ph.D. in chemistry, chemical or environmental engineering, with a solid background in atmospheric and analytical chemistry and technology. Strong publication record. Prior hands-on experience with aerosol analytical and physical chemistry. Expertise with some of the advanced analytical techniques for aerosol technology, such as HR- ToF - AMS, oxidation flow reactors (PAM), aerosol characterization and handling (such as SMPS, APS, CPC, flow control). Experience with analytical chemistry is advantageous (FTIR, Raman and UV-Vis spectroscopy). Additional requirements include practice with handling and interpretation of multi-modal data sets; complex data analysis, computer programming skills, experience in working in a research team environment, good oral and written communication skills, interpersonal skills, initiative, creative and innovative thinking.
Lab website: https://www.weizmann.ac.il/EPS/Rudich/
Contact information: Prof. Yinon Rudich, Department of Earth and Planetary Sciences, Weizmann Institute, Rehovot 76100, Israel
e-mail: yinon.rudich@weizmann.ac.il
Tel: 972 8 934 4237
Department of Earth and Planetary Sciences
Postdoc position
Studying the Microbiome of the atmosphere.
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The atmospheric transport of microorganisms can affect the biodiversity and health of global ecosystems. However, the processes influencing airborne bacterial communities' abundance, composition, and dispersal are still not well understood. We study the aerial microbiome to better understand the structure, function, and ecological drivers of airborne communities transported by dust-plumes in the Eastern Mediterranean. We use state-of-the-art aerosol sampling techniques, Next-generation sequencing (NGS), molecular biology and bioinformatics tools.
We are looking for highly motivated and curious PhD students and PostDocs to join our team.
Required qualifications:
- MSc. or PhD. degree in microbial ecology, environmental genomics or related fields.
- Experience in DNA/RNA extraction techniques.
- Experience in bioinformatic/biostatistical pipelines using R or Python.
- Knowledge on the analysis and interpretation of microbial community genomics data.
The following additional qualifications will be advantageous:
- Background in bioaerosol research or related fields.
- Knowledge on molecular biology and microbiology techniques (i.e., genomic sequencing, qPCR, flow cytometry, cell culturing).
- The generation of NGS sequencing libraries.
Please contact:
Prof. Yinon Rudich
yinon.rudich@weizmann.ac.il
Department of Earth and Planetary Sciences
Weizmann Institute of Science
Department of Earth and Planetary Sciences
Postdoc position
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
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Responsibilities:
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
Explore explainable AI approaches to gain a scientific understanding of the weather events' precursor processes and their physical patterns.
Identify and define unique challenges for AI in the field of remote sensing-driven extreme weather forecast models, and study novel solutions.
Explore the integration of fundamental physical and atmospherical theory (e.g., Navier–Stokes equations) within deep learning architectures.
Study unsupervised approaches for learning concise representations of large-scale spatio-temporal meteorological data sequences for various tasks, including memory compression, clustering, augmentation, and generative purposes.
The candidate is expected to advance the group's current AI capabilities and to be a source of knowledge for various machine learning and data science tasks carried out by other group members, including R&D projects of a drone-based system. Candidates should be passionate about Earth and planetary sciences, working in a small research team, and collaborating with researchers from other disciplines.
Minimum Qualifications:
- PhD in computer sciences/ physics/ environmental science/ engineering /statistics/ related fields
- Reach a theoretical understanding of deep learning and or statistical modeling.
- Proven experience in Python packages such as Scikit-learn, Pytorch, Tensorflow, etc.
- Proven independence, self-management, and self-learning skills
Preferred Background in:
- Experience in the analysis of spatio-temporal data/ remote sensing/ monitoring networks.
Department of Earth and Planetary Sciences
Postdoc position
Develop and explore AI and Machine Learning architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
More Information about Postdoc position
Responsibilities:
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
Explore explainable AI approaches to gain a scientific understanding of the weather events' precursor processes and their physical patterns.
Identify and define unique challenges for AI in the field of remote sensing-driven extreme weather forecast models, and study novel solutions.
Explore the integration of fundamental physical and atmospherical theory (e.g., Navier–Stokes equations) within deep learning architectures.
Study unsupervised approaches for learning concise representations of large-scale spatio-temporal meteorological data sequences for various tasks, including memory compression, clustering, augmentation, and generative purposes.
The candidate is expected to advance the group's current AI capabilities and to be a source of knowledge for various machine learning and data science tasks carried out by other group members, including R&D projects of a drone-based system. Candidates should be passionate about Earth and planetary sciences, working in a small research team, and collaborating with researchers from other disciplines.
Minimum Qualifications:
- PhD in computer sciences/ physics/ environmental science/ engineering /statistics/ related fields
- Reach a theoretical understanding of deep learning and or statistical modeling.
- Proven experience in Python packages such as Scikit-learn, Pytorch, Tensorflow, etc.
- Proven independence, self-management, and self-learning skills
Preferred Background in:
- Experience in the analysis of spatio-temporal data/ remote sensing/ monitoring networks.
Department of Biomolecular Sciences
Postdoc position
OPEN POSTDOC positions
We are seeking highly motivated, independent, committed and curious researchers to join our team as Post-Doc. The projects center on the cellular biology of the malaria parasite, immune response, parasite-host interaction and the field of cell-cell communication.
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Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous. This is a full-time position available from October 2023 for a period of two years with a possibility of a further extension subject to funding availability. Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki. For any informal inquiries please contact us by email at neta.regev-rudzki@weizmann.ac.il
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of laser spin simulators and solvers
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We investigate phase locking of large arrays of coupled lasers in a modified degenerate cavity. We show that the minimal loss lasing solution is mapped to the ground state of an XY spin Hamiltonian with the same coupling matrix provided the intensity of all the lasers is uniform. We study the probability to obtain this ground state for various coupling schemes, system parameters and topological constrains. We demonstrate the effect of crowd synchrony with a sharp transition into an ordered state above a critical number of coupled lasers. Finally, we present recent results demonstrating the ability of our system to solve related problems such as phase retrieval, imaging through scattering medium and more.
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of ultra-cold quantum degenerate Bose and Fermi gas
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In collaboration with Roee Ozeri we form Bose Einstein condensates of rubidium 87 atoms, quantum degenerated fermionic gas of potassium 40 atoms, and their mixtures using laser cooling and evaporative cooling in magnetic and far-detuned optical traps and study their properties. Such dilute quantum gases offer full control of external and internal degrees of freedom and variety of unique interrogation tools that enable precise studies of many body quantum systems.
By using magnetic Feshbach resonances we tune the system from weakly interacting where the it can be simply described by a macroscopic wave function to the strongly interacting where highly correlated many body states can be generated and studied. We study and characterize the coherence, dynamics and elementary excitations of these dilute quantum gases using laser and microwave probes and study new type of an opto-mechanical force when they are illuminated with far-detuned uniform laser beam.
